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S. Pfeffer · SciRah

Researcher profile · Semantic Scholar

S. Pfeffer

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S. Pfeffer — researcher profile on SciRah

h-index: 32
Works: 59
Citations: 4,038

Most-cited papers

Visualizing the molecular sociology at the HeLa cell nuclear periphery
J. Mahamid, S. Pfeffer, M. Schaffer, E. Villa +6 more
2016Science565 citations
Semantic Scholar
PyTom: a python-based toolbox for localization of macromolecules in cryo-electron tomograms and subtomogram analysis.
Thomas Hrabe, Yu-Xiang Chen, S. Pfeffer, Luis Kuhn Cuellar +2 more
2012Journal of Structural Biology254 citations
Semantic Scholar
A cryo-FIB lift-out technique enables molecular-resolution cryo-ET within native Caenorhabditis elegans tissue
M. Schaffer, S. Pfeffer, J. Mahamid, S. Kleindiek +7 more
2019Nature Methods237 citations
Semantic Scholar
Structural basis for coupling of protein transport and N-glycosylation at the mammalian endoplasmic reticulum
K. Braunger, S. Pfeffer, Shiteshu Shrimal, R. Gilmore +5 more
2018Science217 citations Open access
Semantic Scholar
Structure of the native Sec61 protein-conducting channel
S. Pfeffer, L. Burbaum, Pia Unverdorben, Markus Pech +4 more
2015Nature Communications187 citations Open access
Semantic Scholar
Deep learning improves macromolecule identification in 3D cellular cryo-electron tomograms
E. Moebel, A. Martínez-Sánchez, L. Lamm, R. Righetto +10 more
2020Nature Methods175 citations Open access
Semantic Scholar
Ribosome-associated Quality Control (RQC) Mechanisms from Bacteria to Humans
S. Filbeck, Federico Cerullo, S. Pfeffer, C. Joazeiro
2022Molecules and Cells166 citations Open access
Semantic Scholar
Structure of the mammalian oligosaccharyl-transferase complex in the native ER protein translocon
S. Pfeffer, Johanna Dudek, M. Gogala, Stefan Schorr +6 more
2014Nature Communications156 citations Open access
Semantic Scholar
Dissecting the molecular organization of the translocon-associated protein complex
S. Pfeffer, Johanna Dudek, M. Schaffer, B. Ng +7 more
2017Nature Communications144 citations Open access
Semantic Scholar
An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases
Sven Lang, S. Pfeffer, Po-Hsien Lee, A. Cavalié +3 more
2017Frontiers in Physiology144 citations Open access
Semantic Scholar
Organization of the mitochondrial translation machinery studied in situ by cryoelectron tomography
S. Pfeffer, Michael W. Woellhaf, Johannes M. Herrmann, F. Förster
2015Nature Communications134 citations Open access
Semantic Scholar
Biogenic regions of cyanobacterial thylakoids form contact sites with the plasma membrane
Anna Rast, M. Schaffer, S. Albert, W. Wan +5 more
2019Nature Plants131 citations
Semantic Scholar
Insights into the assembly and activation of the microtubule nucleator γ-TuRC
Peng Liu, E. Zupa, A. Neuner, Anna Böhler +9 more
2019Nature120 citations
Semantic Scholar
Structure and 3D arrangement of endoplasmic reticulum membrane-associated ribosomes.
S. Pfeffer, Florian Brandt, Thomas Hrabe, Sven Lang +3 more
2012Structure98 citations Open access
Semantic Scholar
Structure of the Human Mitochondrial Ribosome Studied In Situ by Cryoelectron Tomography.
Robert Englmeier, S. Pfeffer, F. Förster
2017Structure90 citations Open access
Semantic Scholar
Structural Basis of Tail-Anchored Membrane Protein Biogenesis by the GET Insertase Complex.
M. A. McDowell, M. Heimes, F. Fiorentino, S. Mehmood +12 more
2020Molecules and Cells86 citations Open access
Semantic Scholar
Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
Duy Nguyen, Regine Stutz, Stefan Schorr, Sven Lang +6 more
2018Nature Communications83 citations Open access
Semantic Scholar
Protein transport into the human endoplasmic reticulum.
Johanna Dudek, S. Pfeffer, Po-Hsien Lee, M. Jung +4 more
2015Journal of Molecular Biology82 citations
Semantic Scholar
Fast and accurate reference-free alignment of subtomograms.
Yu-Xiang Chen, S. Pfeffer, Thomas Hrabe, J. Schuller +1 more
2013Journal of Structural Biology79 citations
Semantic Scholar
Template-free detection and classification of membrane-bound complexes in cryo-electron tomograms
A. Martínez-Sánchez, Zdravko Kochovski, Ulrike Laugks, Johannes Meyer zum Alten Borgloh +4 more
2020Nature Methods75 citations Open access
Semantic Scholar
Subtomogram analysis using the Volta phase plate.
M. Khoshouei, S. Pfeffer, W. Baumeister, F. Förster +1 more
2017Journal of Structural Biology71 citations Open access
Semantic Scholar
MetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments
K. Wild, M. Aleksić, K. Lapouge, K. D. Juaire +3 more
2020Nature Communications63 citations Open access
Semantic Scholar
Unravelling molecular complexity in structural cell biology.
S. Pfeffer, J. Mahamid
2018Current Opinion in Structural Biology59 citations
Semantic Scholar
Plasma cell deficiency in humans with heterozygous mutations in SEC61A1
D. Schubert, Marie-Christine Klein, Sarah Haßdenteufel, Andrés Caballero-Oteyza +24 more
2017Journal of Allergy and Clinical Immunology57 citations Open access
Semantic Scholar
How to build a ribosome from RNA fragments in Chlamydomonas mitochondria
F. Waltz, Thalia Salinas-Giegé, Robert Englmeier, Herrade Meichel +8 more
2021Nature Communications56 citations Open access
Semantic Scholar
Bacterial ribosome collision sensing by a MutS DNA repair ATPase paralog
Federico Cerullo, S. Filbeck, P. R. Patil, Hao-Chih Hung +9 more
2022Nature53 citations Open access
Semantic Scholar
Microtubule nucleation: The waltz between γ-tubulin ring complex and associated proteins.
Peng Liu, Martin Würtz, E. Zupa, S. Pfeffer +1 more
2020Current Opinion in Cell Biology53 citations
Semantic Scholar
Autofocused 3D classification of cryoelectron subtomograms.
Yu-Xiang Chen, S. Pfeffer, J. Fernández, C. O. Sorzano +1 more
2014Structure53 citations Open access
Semantic Scholar
Organization of the native ribosome-translocon complex at the mammalian endoplasmic reticulum membrane.
S. Pfeffer, Johanna Dudek, R. Zimmermann, F. Förster
2016Biochimica et Biophysica Acta44 citations
Semantic Scholar
Modular assembly of the principal microtubule nucleator γ-TuRC
Martin Würtz, E. Zupa, E. Atorino, A. Neuner +7 more
2022Nature Communications38 citations Open access
Semantic Scholar
Mimicry of canonical translation elongation underlies alanine tail synthesis in RQC
S. Filbeck, Federico Cerullo, Helge Paternoga, G. Tsaprailis +2 more
2020Molecules and Cells37 citations Open access
Semantic Scholar
The structure of the γ-TuRC: a 25-years-old molecular puzzle.
E. Zupa, Peng Liu, Martin Würtz, E. Schiebel +1 more
2020Current Opinion in Structural Biology36 citations
Semantic Scholar
Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress
Ye Zhou, P. Kastritis, Shannon E. Dougherty, J. Bouvette +11 more
2020Proceedings of the National Academy of Sciences of the United States of America30 citations Open access
Semantic Scholar
The augmin complex architecture reveals structural insights into microtubule branching
E. Zupa, Martin Würtz, A. Neuner, Thomas Hoffmann +6 more
2022Nature Communications25 citations Open access
Semantic Scholar
TRAM1 protein may support ER protein import by modulating the phospholipid bilayer near the lateral gate of the Sec61-channel
Marie-Christine Klein, Monika Lerner, Duy Nguyen, S. Pfeffer +5 more
2020Channels20 citations Open access
Semantic Scholar
Detection and identification of macromolecular complexes in cryo-electron tomograms using support vector machines
Yu-Xiang Chen, Thomas Hrabe, S. Pfeffer, Olivier Pauly +3 more
2012IEEE International Symposium on Biomedical Imaging20 citations
Semantic Scholar
Functions and Mechanisms of the Human Ribosome-Translocon Complex.
Sven Lang, Duy Nguyen, S. Pfeffer, F. Förster +2 more
2019Sub-cellular biochemistry18 citations Open access
Semantic Scholar
Mitochondrial dysfunction rapidly modulates the abundance and thermal stability of cellular proteins
C. Groh, P. Haberkant, F. Stein, S. Filbeck +4 more
2022Life Science Alliance15 citations Open access
Semantic Scholar
The gamma‐tubulin ring complex: Deciphering the molecular organization and assembly mechanism of a major vertebrate microtubule nucleator
Anna Böhler, Bram J. A. Vermeulen, Martin Würtz, E. Zupa +2 more
2021Bioessays14 citations Open access
Semantic Scholar
Reconstitution of the recombinant human γ-tubulin ring complex
Martin Würtz, Anna Böhler, A. Neuner, E. Zupa +6 more
2020Open Biology13 citations Open access
Semantic Scholar
Plasma cell deficiency in humans with heterozygous mutations in SEC61A1
D. Schubert, Marie-Christine Klein, Sarah Haßdenteufel, Andrés Caballero Oteyza +24 more
201713 citations
Semantic Scholar
The cryo-EM structure of a γ-TuSC elucidates architecture and regulation of minimal microtubule nucleation systems
E. Zupa, Anjun Zheng, A. Neuner, Martin Würtz +4 more
2020Nature Communications7 citations Open access
Semantic Scholar
Author Correction: Template-free detection and classification of membrane-bound complexes in cryo-electron tomograms
A. Martínez-Sánchez, Zdravko Kochovski, Ulrike Laugks, Johannes Meyer zum Alten Borgloh +4 more
2020Nature Methods6 citations Open access
Semantic Scholar
Sec61: A static framework for membrane-protein insertion
S. Pfeffer, F. Förster
2016Channels5 citations Open access
Semantic Scholar
Translational Activity Controls Ribophagic Flux and Turnover of Distinct Ribosome Pools
Jakob Trendel, M. Aleksić, M. Bertolini, Marco Jochem +4 more
2022bioRxiv4 citations Open access
Semantic Scholar
Structural Biology in Situ Using Cryo-Electron Subtomogram Analysis
S. Pfeffer, F. Förster
20184 citations
Semantic Scholar
Cryo-FIB Lamella Milling: A Comprehensive Technique to Prepare Samples of Both Plunge- and High-pressure Frozen-hydrated Specimens for in situ Studies.
M. Schaffer, S. Pfeffer, S. Kleindiek, J. Mahamid +7 more
2018Microscopy and Microanalysis3 citations Open access
Semantic Scholar
Template-free detection and classification of heterogeneous membrane-bound complexes in cryo-electron tomograms
A. Martínez-Sánchez, Zdravko Kochovski, Ulrike Laugks, Johannes Meyer zum Alten Borgloh +4 more
2018bioRxiv3 citations Open access
Semantic Scholar
Protocol for cryo-focused ion beam lift-out technique
M. Schaffer, S. Pfeffer, J. Mahamid, S. Kleindiek +7 more
20191 citations Open access
Semantic Scholar
Towards High Resolution in Cryo-Electron Tomography Subtomogram Analysis
S. Pfeffer, M. Khoshouei, R. Danev, F. Förster
2017Microscopy and Microanalysis1 citations Open access
Semantic Scholar

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