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D. Pearson · SciRah

Researcher profile · Semantic Scholar

D. Pearson

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D. Pearson — researcher profile on SciRah

h-index: 22
Works: 30
Citations: 4,207

Most-cited papers

The DNA sequence of the human X chromosome
M. Ross, D. Grafham, A. Coffey, S. Scherer +278 more
2005Nature1,115 citations Open access
Semantic Scholar
Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas
David T. W. Jones, S. Kocialkowski, Lu Liu, D. Pearson +3 more
2008Cancer Research875 citations Open access
Semantic Scholar
IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas
K. Ichimura, D. Pearson, S. Kocialkowski, L. Bäcklund +3 more
2009Neuro-Oncology618 citations Open access
Semantic Scholar
Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma
David T. W. Jones, S. Kocialkowski, Lu Liu, D. Pearson +2 more
2009Oncogene322 citations Open access
Semantic Scholar
Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours
Louise Harewood, K. Kishore, Matthew Eldridge, S. Wingett +4 more
2017Genome Biology168 citations Open access
Semantic Scholar
A distinct region of the MGMT CpG island critical for transcriptional regulation is preferentially methylated in glioblastoma cells and xenografts
Deborah S. Malley, R. Hamoudi, S. Kocialkowski, D. Pearson +2 more
2011Acta Neuropathologica136 citations
Semantic Scholar
High resolution array-based comparative genomic hybridisation of medulloblastomas and supra-tentorial primitive neuroectodermal tumours
M. McCabe, K. Ichimura, Lu Liu, K. Plant +3 more
2006Journal of Neuropathology and Experimental Neurology94 citations Open access
Semantic Scholar
Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma
S. Lambert, H. Witt, V. Hovestadt, M. Zucknick +11 more
2013Acta Neuropathologica92 citations
Semantic Scholar
Genomic Analysis of Pilocytic Astrocytomas at 0.97 Mb Resolution Shows an Increasing Tendency Toward Chromosomal Copy Number Change With Age
David T. W. Jones, K. Ichimura, Lu Liu, D. Pearson +2 more
2006Journal of Neuropathology and Experimental Neurology86 citations Open access
Semantic Scholar
Application of Array CGH on Archival Formalin-Fixed Paraffin-Embedded Tissues including small numbers of microdissected cells
Nicola A. Johnson, R. Hamoudi, K. Ichimura, Lu Liu +3 more
2006Laboratory Investigation83 citations Open access
Semantic Scholar
MGMT CpG island is invariably methylated in adult astrocytic and oligodendroglial tumors with IDH1 or IDH2 mutations
S. Mulholland, D. Pearson, R. Hamoudi, Deborah S. Malley +7 more
2012International Journal of Cancer82 citations
Semantic Scholar
Distinct patterns of 1p and 19q alterations identify subtypes of human gliomas that have different prognoses.
Artemis P. Vogazianou, R. Chan, L. Bäcklund, D. Pearson +5 more
2010Neuro-Oncology78 citations Open access
Semantic Scholar
Small regions of overlapping deletions on 6q26 in human astrocytic tumours identified using chromosome 6 tile path array CGH
K. Ichimura, A. Mungall, H. Fiegler, D. Pearson +3 more
2006Oncogene66 citations Open access
Semantic Scholar
An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures
G. Collord, P. Tarpey, N. Kurbatova, I. Martincorena +35 more
2017Scientific Reports65 citations Open access
Semantic Scholar
Adult grade II diffuse astrocytomas are genetically distinct from and more aggressive than their paediatric counterparts
David T. W. Jones, S. Mulholland, D. Pearson, Deborah S. Malley +6 more
2011Acta Neuropathologica53 citations
Semantic Scholar
Complex chromosome 22 rearrangements in astrocytic tumors identified using microsatellite and chromosome 22 tile path array analysis
Tzer Jing Seng, K. Ichimura, Lu Liu, O. Tingby +2 more
2005Genes, Chromosomes and Cancer53 citations
Semantic Scholar
The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X
D. Bentley, P. Deloukas, A. Dunham, L. French +97 more
2001Nature52 citations Open access
Semantic Scholar
Neutropenia and anaemia associated with T‐cell large granular lymphocyte leukaemia responds to fludarabine with minimal toxicity
A. Sternberg, H. Eagleton, N. Pillai, K. Leyden +4 more
2003British Journal of Haematology35 citations
Semantic Scholar
Prognostic and predictive markers in recurrent high grade glioma; results from the BR12 randomised trial
V. Collins, K. Ichimura, Ying Di, D. Pearson +5 more
2014Acta Neuropathologica Communications32 citations Open access
Semantic Scholar
DNA sequence of the cut A, B and C genes, encoding the molybdenum containing hydroxylase carbon monoxide dehydrogenase, from Pseudomonas thermocarboxydovorans strain C2.
D. Pearson, Catherine O'Reilly, John Colby, G. Black
1994Biochimica et Biophysica Acta26 citations
Semantic Scholar
CpG island hypermethylation of the neurofibromatosis type 2 (NF2) gene is rare in sporadic vestibular schwannomas
P. Kullar, D. Pearson, D. S. Malley, V. Collins +1 more
2010Neuropathology and Applied Neurobiology24 citations
Semantic Scholar
Genome-Wide Analysis of Subependymomas Shows Underlying Chromosomal Copy Number Changes Involving Chromosomes 6, 7, 8 and 14 in a Proportion of Cases
K. Kurian, David T. W. Jones, Faye Marsden, Sam Openshaw +3 more
2008Brain Pathology22 citations Open access
Semantic Scholar
p53-independent mechanisms regulate the P2-MDM2 promoter in adult astrocytic tumours
Maria Dimitriadi, George Poulogiannis, Lu Liu, L. Bäcklund +3 more
2008British Journal of Cancer17 citations Open access
Semantic Scholar
Novel mechanisms of gene disruption at the medulloblastoma isodicentric 17p11 breakpoint
Martin G. McCabe, K. Ichimura, D. Pearson, Lu Liu +3 more
2009Genes, Chromosomes and Cancer9 citations
Semantic Scholar
Prognostic and predictive markers in recurrent high grade glioma ; results from the BR 12 randomised trial
V. Collins, K. Ichimura, Ying Di, D. Pearson +5 more
20143 citations
Semantic Scholar
Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours
L. Harewood, K. Kishore, Matthew Eldridge, S. Wingett +4 more
2017Genome Biology1 citations Open access
Semantic Scholar
Prognostic and predictive markers in recurrent high grade glioma; results from the BR12 randomised trial
V. Collins, K. Ichimura, Ying Di, D. Pearson +5 more
2014Acta Neuropathologica Communications1 citations Open access
Semantic Scholar
University of Birmingham An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures
Patrick, Natalja, Iñigo, Manuel +33 more
20180 citations
Semantic Scholar
Abstract 3807: Integrative genomic profiling of pilocytic astrocytomas reveals location specific differential methylation and expression of brain developmental genes.
S. Lambert, H. Witt, V. Hovestadt, M. Zucknick +6 more
20130 citations
Semantic Scholar
Abstract 2794: Mutation ofIDH1/2is strongly associated withMGMTmethylation in adult astrocytic and oligodendroglial tumors
S. Mulholland, Deborah S. Malley, R. Hamoudi, S. Kocialkowski +3 more
20110 citations
Semantic Scholar

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