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K. Nagai · SciRah

Researcher profile · Semantic Scholar

K. Nagai

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K. Nagai — researcher profile on SciRah

h-index: 46
Works: 174
Citations: 9,827

Most-cited papers

RNA Splicing by the Spliceosome.
M. E. Wilkinson, C. Charenton, K. Nagai
2019Annual Review of Biochemistry617 citations
Semantic Scholar
Crystal structure of human spliceosomal U1 snRNP at 5.5 Å resolution
D. P. Pomeranz Krummel, C. Oubridge, A. Leung, Jade Li +1 more
2009Nature369 citations Open access
Semantic Scholar
Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5′ splice site recognition
Y. Kondo, C. Oubridge, A. V. van Roon, K. Nagai
2015eLife228 citations Open access
Semantic Scholar
The architecture of the spliceosomal U4/U6.U5 tri-snRNP
Thi Hoang Duong Nguyen, W. P. Galej, Xiao-Chen Bai, C. Savva +3 more
2015Nature225 citations Open access
Semantic Scholar
Structure of a pre-catalytic spliceosome
C. Plaschka, P. Lin, K. Nagai
2017Nature223 citations Open access
Semantic Scholar
Crystal structure of Prp8 reveals active site cavity of the spliceosome
W. P. Galej, C. Oubridge, A. J. Newman, K. Nagai
2013Nature216 citations Open access
Semantic Scholar
CryoEM structure of the spliceosome immediately after branching
W. P. Galej, M. E. Wilkinson, S. Fica, C. Oubridge +2 more
2016Nature215 citations Open access
Semantic Scholar
CryoEM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Å resolution
Thi Hoang Duong Nguyen, W. P. Galej, Xiao-Chen Bai, C. Oubridge +3 more
2016Nature212 citations Open access
Semantic Scholar
Recognition of a signal peptide by the signal recognition particle
C. Y. Janda, Jade Li, C. Oubridge, Helena Hernández +2 more
2010Nature208 citations Open access
Semantic Scholar
Cryo-EM snapshots of the spliceosome: structural insights into a dynamic ribonucleoprotein machine
S. Fica, K. Nagai
2017Nature Structural &Molecular Biology168 citations Open access
Semantic Scholar
Mechanism of 5′ splice site transfer for human spliceosome activation
C. Charenton, M. E. Wilkinson, K. Nagai
2019Science160 citations Open access
Semantic Scholar
Structure of a spliceosome remodelled for exon ligation
S. Fica, C. Oubridge, W. P. Galej, M. E. Wilkinson +3 more
2017Nature158 citations Open access
Semantic Scholar
Prespliceosome structure provides insights into spliceosome assembly and regulation
C. Plaschka, P. Lin, C. Charenton, K. Nagai
2018Nature147 citations Open access
Semantic Scholar
Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis
A. Leung, K. Nagai, Jade Li
2011Nature130 citations Open access
Semantic Scholar
Post-catalytic spliceosome structure reveals mechanism of 3'-splice site selection
M. E. Wilkinson, S. Fica, W. P. Galej, C. Norman +2 more
2017Science113 citations Open access
Semantic Scholar
A human post-catalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation
S. Fica, C. Oubridge, M. E. Wilkinson, A. J. Newman +1 more
2019Science110 citations Open access
Semantic Scholar
Induced structural changes of 7SL RNA during the assembly of human signal recognition particle
A. Kuglstatter, C. Oubridge, K. Nagai
2002Nature Structural Biology109 citations
Semantic Scholar
Structural Basis of Nuclear pre-mRNA Splicing: Lessons from Yeast.
C. Plaschka, A. J. Newman, K. Nagai
2019Cold Spring Harbor Perspectives in Biology94 citations Open access
Semantic Scholar
Pigment chemistry: The red sweat of the hippopotamus
Y. Saikawa, K. Hashimoto, M. Nakata, M. Yoshihara +3 more
2004Nature80 citations
Semantic Scholar
Crystal structure of SRP19 in complex with the S domain of SRP RNA and its implication for the assembly of the signal recognition particle.
C. Oubridge, A. Kuglstatter, L. Jovine, K. Nagai
2002Molecules and Cells79 citations Open access
Semantic Scholar
The structure and biochemical properties of the human spliceosomal protein U1C.
Y. Muto, D. P. Pomeranz Krummel, C. Oubridge, Helena Hernández +3 more
2004Journal of Molecular Biology66 citations
Semantic Scholar
Structural studies of the spliceosome: zooming into the heart of the machine
W. P. Galej, Thi Hoang Duong Nguyen, A. J. Newman, K. Nagai
2014Current Opinion in Structural Biology62 citations Open access
Semantic Scholar
Molecular Mechanism and Evolution of Nuclear Pre-mRNA and Group II Intron Splicing: Insights from Cryo-Electron Microscopy Structures.
W. P. Galej, N. Toor, A. J. Newman, K. Nagai
2018Chemical Reviews58 citations Open access
Semantic Scholar
Crystallization of RNA-protein complexes.
E. Obayashi, C. Oubridge, D. P. Pomeranz Krummel, K. Nagai
2007Methods in molecular biology57 citations
Semantic Scholar
Structural studies of the spliceosome: blind men and an elephant.
A. J. Newman, K. Nagai
2010Current Opinion in Structural Biology52 citations
Semantic Scholar
Structural basis for conformational equilibrium of the catalytic spliceosome
M. E. Wilkinson, S. Fica, W. P. Galej, K. Nagai
2020bioRxiv50 citations Open access
Semantic Scholar
CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast
Thi Hoang Duong Nguyen, W. P. Galej, S. Fica, P. Lin +2 more
2016Current Opinion in Structural Biology48 citations Open access
Semantic Scholar
Structure and assembly of the spliceosomal snRNPs. Novartis Medal Lecture.
K. Nagai, Y. Muto, D. P. Pomeranz Krummel, C. Kambach +3 more
2001Biochemical Society Transactions44 citations
Semantic Scholar
Assembly and dynamics of the U4/U6 di-snRNP by single-molecule FRET
J. Hardin, Chandani Warnasooriya, Y. Kondo, K. Nagai +1 more
2015Nucleic Acids Research41 citations Open access
Semantic Scholar
Protein-induced conformational changes of RNA during the assembly of human signal recognition particle.
E. Menichelli, C. Isel, C. Oubridge, K. Nagai
2007Journal of Molecular Biology39 citations
Semantic Scholar
Cryo-EM Studies of Pre-mRNA Splicing: From Sample Preparation to Model Visualization.
M. E. Wilkinson, P. Lin, C. Plaschka, K. Nagai
2018Annual Review of Biophysics25 citations
Semantic Scholar
Solution structure of the U2 snRNP protein Rds3p reveals a knotted zinc-finger motif
A. V. van Roon, N. Loening, E. Obayashi, Ji-Chun Yang +4 more
2008Proceedings of the National Academy of Sciences of the United States of America25 citations Open access
Semantic Scholar
CryoEM structures of spliceosomal complexes reveal the molecular mechanism of pre-mRNA splicing.
S. Scheres, K. Nagai
2017Current Opinion in Structural Biology20 citations
Semantic Scholar
Re-refinement of the spliceosomal U4 snRNP core-domain structure
Jade Li, A. Leung, Y. Kondo, C. Oubridge +1 more
2016Acta Crystallographica Section D: Structural Biology20 citations Open access
Semantic Scholar
psiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation
Lisa M. Strittmatter, Charlotte Capitanchik, A. J. Newman, Martina Hallegger +6 more
2020Nature Communications16 citations Open access
Semantic Scholar
Structural basis of the interaction between P-element somatic inhibitor and U1-70k essential for the alternative splicing of P-element transposase.
T. Ignjatovic, Ji-Chun Yang, J. Butler, D. Neuhaus +1 more
2005Journal of Molecular Biology16 citations
Semantic Scholar
Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain
A. V. van Roon, C. Oubridge, E. Obayashi, B. Sposito +3 more
2017RNA: A publication of the RNA Society15 citations Open access
Semantic Scholar
Use of RNA tertiary interaction modules for the crystallisation of the spliceosomal snRNP core domain.
A. Leung, C. Kambach, Y. Kondo, M. Kampmann +2 more
2010Journal of Molecular Biology14 citations
Semantic Scholar
Interpreting a Low Resolution Map of Human U1 snRNP Using Anomalous Scatterers
C. Oubridge, D. P. Pomeranz Krummel, A. Leung, Jade Li +1 more
2009Structure13 citations Open access
Semantic Scholar
Chemical Synthesis of U1 snRNA Derivatives
A. Ohkubo, Y. Kondo, Makoto Suzuki, Haruki Kobayashi +5 more
2013Organic Letters12 citations Open access
Semantic Scholar
Author response: Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5′ splice site recognition
Y. Kondo, C. Oubridge, A. V. van Roon, K. Nagai
201411 citations Open access
Semantic Scholar
Structure of spliceosomal ribonucleoproteins
D. Krummel, K. Nagai, C. Oubridge
2010F1000 Biology Reports9 citations Open access
Semantic Scholar
113Cd NMR Experiments Reveal an Unusual Metal Cluster in the Solution Structure of the Yeast Splicing Protein Bud31p
A. V. van Roon, Ji-Chun Yang, D. Mathieu, W. Bermel +2 more
2015Angewandte Chemie6 citations Open access
Semantic Scholar
113Cd NMR Experiments Reveal an Unusual Metal Cluster in the Solution Structure of the Yeast Splicing Protein Bud31p
A. V. van Roon, Ji-Chun Yang, D. Mathieu, W. Bermel +2 more
2015Angewandte Chemie5 citations Open access
Semantic Scholar
RNA–protein interactions in the U4 snRNP core domain
J. Li, A. Leung, K. Nagai
20085 citations Open access
Semantic Scholar
Diversity makes for a rich tapestry.
Song Tan, K. Nagai
2011Current Opinion in Structural Biology4 citations
Semantic Scholar
Crystal Structure of a Ten-Subunit Human Spliceosomal U1 snRNP at 5.5 Å Resolution
D. P. Pomeranz Krummel, C. Oubridge, A. Leung, Jade Li +1 more
20114 citations Open access
Semantic Scholar
Cryo-Em Snapshots of the Spliceosome
K. Nagai
20183 citations Open access
Semantic Scholar
Structure of the spliceosomal U4 snRNP core domain
A. Leung, K. Nagai, J. Li
20113 citations
Semantic Scholar
Mutagenic Studies on the Origins of the Root Effect
S. Unzai, K. Imai, Sam-Yong Park, K. Nagai +2 more
20083 citations
Semantic Scholar

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C. Oubridge×20
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A. J. Newman×15
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W. P. Galej×10
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A. Leung — researcher profile on SciRah

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