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J. Drouin · SciRah

Researcher profile · Semantic Scholar

J. Drouin

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J. Drouin — researcher profile on SciRah

h-index: 68
Works: 182
Citations: 16K

Most-cited papers

Pitx3 is required for motor activity and for survival of a subset of midbrain dopaminergic neurons
P. van den Munckhof, Kelvin C. Luk, Line Ste-Marie, Jane A. Montgomery +3 more
2003Development312 citations Open access
Semantic Scholar
Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease.
S. Bilodeau, Sophie Vallette-Kasic, Y. Gauthier, D. Figarella-Branger +8 more
2006Genes & Development243 citations Open access
Semantic Scholar
Pioneer factors as master regulators of the epigenome and cell fate
A. Balsalobre, J. Drouin
2022Nature reviews. Molecular cell biology214 citations
Semantic Scholar
Pioneer transcription factors shape the epigenetic landscape
Alexandre Mayran, J. Drouin
2018Journal of Biological Chemistry202 citations Open access
Semantic Scholar
Pitx1 and Pitx2 are required for development of hindlimb buds
Alexandre Marcil, Émilie Dumontier, Michel Chamberland, S. Camper +1 more
2003Development188 citations
Semantic Scholar
The Stat3/GR interaction code: predictive value of direct/indirect DNA recruitment for transcription outcome.
D. Langlais, C. Couture, A. Balsalobre, J. Drouin
2012Molecules and Cells183 citations Open access
Semantic Scholar
Pioneer factor Pax7 deploys a stable enhancer repertoire for specification of cell fate
Alexandre Mayran, Konstantin Khetchoumian, F. Hariri, T. Pastinen +3 more
2018Nature Genetics151 citations
Semantic Scholar
The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling.
L. Budry, A. Balsalobre, Y. Gauthier, Konstantin Khetchoumian +6 more
2012Genes & Development145 citations Open access
Semantic Scholar
PITX genes are required for cell survival and Lhx3 activation.
Michael A. Charles, H. Suh, T. Hjalt, J. Drouin +2 more
2005Molecular Endocrinology136 citations
Semantic Scholar
Distinct Developmental Roles of Cell Cycle Inhibitors p57Kip2 and p27Kip1 Distinguish Pituitary Progenitor Cell Cycle Exit from Cell Cycle Reentry of Differentiated Cells
S. Bilodeau, A. Roussel-Gervais, J. Drouin
2009Molecular and Cellular Biology125 citations Open access
Semantic Scholar
Protein-protein interactions and transcriptional antagonism between the subfamily of NGFI-B/Nur77 orphan nuclear receptors and glucocorticoid receptor.
C. Martens, S. Bilodeau, M. Maira, Y. Gauthier +1 more
2005Molecular Endocrinology125 citations Open access
Semantic Scholar
Formation and Differentiation of Multiple Mesenchymal Lineages during Lung Development Is Regulated by β-catenin Signaling
S. D. De Langhe, G. Carraro, D. Tefft, Chang-Gong Li +7 more
2008PLoS ONE121 citations Open access
Semantic Scholar
A tridimensional view of pituitary development and function.
P. Mollard, D. Hodson, C. Lafont, K. Rizzoti +1 more
2012Trends in endocrinology and metabolism119 citations
Semantic Scholar
Congenital isolated adrenocorticotropin deficiency: an underestimated cause of neonatal death, explained by TPIT gene mutations.
Sophie Vallette-Kasic, T. Brue, Anne-Marie Pulichino, M. Gueydan +32 more
2005Journal of Clinical Endocrinology and Metabolism118 citations Open access
Semantic Scholar
Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening
Alexandre Mayran, K. Sochodolsky, Konstantin Khetchoumian, Juliette Harris +4 more
2019Nature Communications115 citations Open access
Semantic Scholar
Related pituitary cell lineages develop into interdigitated 3D cell networks
L. Budry, C. Lafont, Taoufik El Yandouzi, N. Chauvet +3 more
2011Proceedings of the National Academy of Sciences of the United States of America113 citations Open access
Semantic Scholar
Characterization of Pancreatic Transcription Factor Pdx-1 Binding Sites Using Promoter Microarray and Serial Analysis of Chromatin Occupancy*
D. M. Keller, S. McWeeney, Athanasios Arsenlis, J. Drouin +6 more
2007Journal of Biological Chemistry106 citations Open access
Semantic Scholar
Sequential expression and redundancy of Pitx2 and Pitx3 genes during muscle development.
Aurore L'honoré, Vincent Coulon, Alexandre Marcil, Mélanie Lebel +4 more
2007Developmental Biology92 citations Open access
Semantic Scholar
Mutations in NFKB2 and potential genetic heterogeneity in patients with DAVID syndrome, having variable endocrine and immune deficiencies
T. Brue, M. Quentien, Konstantin Khetchoumian, Marco Bensa +16 more
2014BMC Medical Genetics84 citations Open access
Semantic Scholar
60 YEARS OF POMC: Transcriptional and epigenetic regulation of POMC gene expression.
J. Drouin
2016Journal of Molecular Endocrinology79 citations Open access
Semantic Scholar
Cooperation between cyclin E and p27(Kip1) in pituitary tumorigenesis.
A. Roussel-Gervais, S. Bilodeau, S. Vallette, F. Berthelet +4 more
2010Molecular Endocrinology79 citations Open access
Semantic Scholar
Distal Limb Patterning Requires Modulation of cis-Regulatory Activities by HOX13
Rushikesh Sheth, I. Barozzi, D. Langlais, M. Osterwalder +6 more
2016Cell Reports76 citations Open access
Semantic Scholar
Phenotypic homogeneity and genotypic variability in a large series of congenital isolated ACTH-deficiency patients with TPIT gene mutations.
C. Couture, A. Saveanu, A. Barlier, J. Carel +9 more
2012Journal of Clinical Endocrinology and Metabolism75 citations
Semantic Scholar
Pitx2 defines alternate pathways acting through MyoD during limb and somitic myogenesis
Aurore L'honoré, Jean-François Ouimette, Marisol Lavertu-Jolin, J. Drouin
2010Development72 citations Open access
Semantic Scholar
Tpit-independent function of NeuroD1(BETA2) in pituitary corticotroph differentiation.
B. Lamolet, G. Poulin, K. Chu, F. Guillemot +2 more
2004Molecular Endocrinology72 citations Open access
Semantic Scholar
The role of Pitx2 and Pitx3 in muscle stem cells gives new insights into P38α MAP kinase and redox regulation of muscle regeneration
Aurore L'honoré, P. Commère, E. Negroni, G. Pallafacchina +4 more
2018eLife71 citations Open access
Semantic Scholar
Deletion of the Pitx1 genomic locus affects mandibular tooth morphogenesis and expression of the Barx1 and Tbx1 genes.
T. Mitsiadis, J. Drouin
2008Developmental Biology70 citations Open access
Semantic Scholar
The transcription factor Pitx3 is expressed selectively in midbrain dopaminergic neurons susceptible to neurodegenerative stress
Kelvin C. Luk, V. Rymar, P. van den Munckhof, Stefan Nicolau +4 more
2013Journal of Neurochemistry64 citations
Semantic Scholar
The Cables1 Gene in Glucocorticoid Regulation of Pituitary Corticotrope Growth and Cushing Disease.
A. Roussel-Gervais, C. Couture, D. Langlais, Shinobu Takayasu +6 more
2016Journal of Clinical Endocrinology and Metabolism62 citations
Semantic Scholar
TIF1β/KAP-1 Is a Coactivator of the Orphan Nuclear Receptor NGFI-B/Nur77*
Juliette Rambaud, J. Desroches, A. Balsalobre, J. Drouin
2009Journal of Biological Chemistry62 citations Open access
Semantic Scholar
Divergent transcriptional activities determine limb identity
Jean-François Ouimette, Marisol Lavertu Jolin, Aurore L'honoré, Anthony J. Gifuni +1 more
2010Nature Communications60 citations Open access
Semantic Scholar
Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors
Irene Delgado, G. Giovinazzo, Susana Temiño, Y. Gauthier +3 more
2021Nature Communications58 citations Open access
Semantic Scholar
Bone morphogenic protein (Smad)-mediated repression of proopiomelanocortin transcription by interference with Pitx/Tpit activity.
M. Nudi, Jean-François Ouimette, J. Drouin
2005Molecular Endocrinology56 citations Open access
Semantic Scholar
Regulatory Network Analyses Reveal Genome-Wide Potentiation of LIF Signaling by Glucocorticoids and Define an Innate Cell Defense Response
D. Langlais, C. Couture, A. Balsalobre, J. Drouin
2008PLoS Genetics55 citations Open access
Semantic Scholar
Pax factors in transcription and epigenetic remodelling.
Alexandre Mayran, Audrey Pelletier, J. Drouin
2015Seminars in Cell and Developmental Biology54 citations
Semantic Scholar
Rgs6 is Required for Adult Maintenance of Dopaminergic Neurons in the Ventral Substantia Nigra
P. Bifsha, Jian-Qi Yang, R. Fisher, J. Drouin
2014PLoS Genetics54 citations Open access
Semantic Scholar
Striatal neuroadaptation and rescue of locomotor deficit by l‐dopa in aphakia mice, a model of Parkinson's disease
P. van den Munckhof, F. Gilbert, Michel Chamberland, D. Lévesque +1 more
2006Journal of Neurochemistry52 citations
Semantic Scholar
Mesenchymal patterning by Hoxa2 requires blocking Fgf-dependent activation of Ptx1
N. Bobola, Marta Carapuço, Sabine Ohnemus, B. Kanzler +4 more
2003Development51 citations
Semantic Scholar
Minireview: pioneer transcription factors in cell fate specification.
J. Drouin
2014Molecular Endocrinology50 citations Open access
Semantic Scholar
HOX13-dependent chromatin accessibility underlies the transition towards the digit development program
Inès Desanlis, Yacine Kherdjemil, Alexandre Mayran, Yasser Bouklouch +5 more
2020Nature Communications48 citations Open access
Semantic Scholar
Redox regulation by Pitx2 and Pitx3 is critical for fetal myogenesis.
Aurore L'honoré, P. Commère, Jean-François Ouimette, D. Montarras +2 more
2014Developmental Cell48 citations Open access
Semantic Scholar
Adult pituitary cell maintenance: lineage-specific contribution of self-duplication.
D. Langlais, C. Couture, Marie Kmita, J. Drouin
2013Molecular Endocrinology47 citations Open access
Semantic Scholar
Rb Enhances p160/SRC Coactivator-dependent Activity of Nuclear Receptors and Hormone Responsiveness*
E. Batsché, J. Desroches, S. Bilodeau, Y. Gauthier +1 more
2005Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Redox Regulation by Pitx2 and Pitx3 Is Critical for Fetal Myogenesis.
Aurore L'honoré, P. Commère, Jean-François Ouimette, D. Montarras +2 more
2016Developmental Cell46 citations Open access
Semantic Scholar
A pituitary-specific enhancer of the POMC gene with preferential activity in corticotrope cells.
D. Langlais, C. Couture, Guillaume Sylvain-Drolet, J. Drouin
2011Molecular Endocrinology44 citations Open access
Semantic Scholar
Pituitary cell translation and secretory capacities are enhanced cell autonomously by the transcription factor Creb3l2
Konstantin Khetchoumian, A. Balsalobre, Alexandre Mayran, H. Christian +3 more
2019Nature Communications43 citations Open access
Semantic Scholar
Human iPSC-Derived Down Syndrome Astrocytes Display Genome-Wide Perturbations in Gene Expression, an Altered Adhesion Profile, and Increased Cellular Dynamics.
Blandine Ponroy Bally, W. T. Farmer, E. Jones, Selin Jessa +8 more
2020Human Molecular Genetics42 citations Open access
Semantic Scholar
Pituitary homeobox 2 regulates adrenal4 binding protein/steroidogenic factor-1 gene transcription in the pituitary gonadotrope through interaction with the intronic enhancer.
Y. Shima, M. Zubair, T. Komatsu, Sanae Oka +5 more
2008Molecular Endocrinology39 citations Open access
Semantic Scholar
Pitx1 directly modulates the core limb development program to implement hindlimb identity
S. Nemec, Maëva Luxey, Deepak Jain, Aurélie Huang Sung +2 more
2017Development36 citations
Semantic Scholar
A Muscle-specific Promoter Directs Pitx3 Gene Expression in Skeletal Muscle Cells*
Vincent Coulon, Aurore L'honoré, Jean-François Ouimette, Émilie Dumontier +2 more
2007Journal of Biological Chemistry36 citations Open access
Semantic Scholar

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