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J. Shaughnessy · SciRah

Researcher profile · Semantic Scholar

J. Shaughnessy

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J. Shaughnessy — researcher profile on SciRah

h-index: 81
Works: 387
Citations: 25K

Most-cited papers

Consensus recommendations for risk stratification in multiple myeloma: report of the International Myeloma Workshop Consensus Panel 2.
N. Munshi, K. Anderson, P. Bergsagel, J. Shaughnessy +16 more
2011Blood340 citations Open access
Semantic Scholar
Superior results of Total Therapy 3 (2003-33) in gene expression profiling-defined low-risk multiple myeloma confirmed in subsequent trial 2006-66 with VRD maintenance.
B. Nair, F. van Rhee, J. Shaughnessy, E. Anaissie +6 more
2010Blood214 citations Open access
Semantic Scholar
Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma
D. Hose, T. Rème, T. Hielscher, J. Moreaux +14 more
2011Haematologica206 citations Open access
Semantic Scholar
Clinical, genomic, and imaging predictors of myeloma progression from asymptomatic monoclonal gammopathies (SWOG S0120).
M. Dhodapkar, R. Sexton, S. Waheed, S. Usmani +8 more
2014Blood188 citations Open access
Semantic Scholar
Pharmacogenomics of bortezomib test-dosing identifies hyperexpression of proteasome genes, especially PSMD4, as novel high-risk feature in myeloma treated with Total Therapy 3.
J. Shaughnessy, Ping-Ping Qu, S. Usmani, C. Heuck +14 more
2011Blood171 citations Open access
Semantic Scholar
Diagnostic Usefulness and Prognostic Impact of CD200 Expression in Lymphoid Malignancies and Plasma Cell Myeloma
Daisy V. Alapat, J. Coviello-malle, Rebecca B. Owens, Ping-Ping Qu +3 more
2012American Journal of Clinical Pathology138 citations Open access
Semantic Scholar
Risk of infections associated with the use of bispecific antibodies in multiple myeloma: a pooled analysis
F. Mazahreh, L. Mazahreh, C. Schinke, S. Thanendrarajan +5 more
2022Blood Advances136 citations Open access
Semantic Scholar
Total Therapy 3 for multiple myeloma: prognostic implications of cumulative dosing and premature discontinuation of VTD maintenance components, bortezomib, thalidomide, and dexamethasone, relevant to all phases of therapy.
F. van Rhee, J. Szymonifka, E. Anaissie, B. Nair +7 more
2010Blood116 citations Open access
Semantic Scholar
Highly activated and expanded natural killer cells for multiple myeloma immunotherapy
T. Garg, S. Szmania, Junaid A. Khan, A. Hoering +16 more
2012Haematologica106 citations Open access
Semantic Scholar
Primary plasma cell leukemia: clinical and laboratory presentation, gene-expression profiling, and clinical outcome with Total Therapy protocols
S. Usmani, B. Nair, Ping-Ping Qu, E. Hansen +15 more
2012Leukemia79 citations Open access
Semantic Scholar
An intermediate-risk multiple myeloma subgroup is defined by sIL-6r: levels synergistically increase with incidence of SNP rs2228145 and 1q21 amplification.
O. Stephens, Qing Zhang, Ping-Ping Qu, Yi-Ming Zhou +6 more
2012Blood68 citations Open access
Semantic Scholar
Role of Bruton’s tyrosine kinase in myeloma cell migration and induction of bone disease
Rakesh Bam, W. Ling, Sharmin Khan, A. Pennisi +8 more
2013American journal of hematology/oncology65 citations Open access
Semantic Scholar
Geographic and Racial Disparities in Access to Chimeric Antigen Receptor–T Cells and Bispecific Antibodies Trials for Multiple Myeloma
R. Al-Qazaqi, C. Schinke, S. Thanendrarajan, M. Zangari +5 more
2022JAMA Network Open60 citations Open access
Semantic Scholar
Interleukin-6 Receptor Polymorphism Is Prevalent in HIV-negative Castleman Disease and Is Associated with Increased Soluble Interleukin-6 Receptor Levels
Katie Stone, E. Woods, S. Szmania, O. Stephens +8 more
2013PLoS ONE55 citations Open access
Semantic Scholar
Developing and Validating Continuous Genomic Signatures in Randomized Clinical Trials for Predictive Medicine
S. Matsui, R. Simon, Ping-Ping Qu, J. Shaughnessy +2 more
2012Clinical Cancer Research52 citations Open access
Semantic Scholar
Prediction of cytogenetic abnormalities with gene expression profiles.
Yi-Ming Zhou, Qing Zhang, O. Stephens, C. Heuck +8 more
2012Blood44 citations Open access
Semantic Scholar
Clinical, Immunophenotypic, and Genetic Characterization of Small Lymphocyte–Like Plasma Cell Myeloma
Amy E Heerema-McKenney, J. Waldron, S. Hughes, F. Zhan +3 more
2010American Journal of Clinical Pathology43 citations Open access
Semantic Scholar
The use of molecular-based risk stratification and pharmacogenomics for outcome prediction and personalized therapeutic management of multiple myeloma
Sarah K. Johnson, C. Heuck, A. Albino, Ping-Ping Qu +3 more
2011International journal of hematology37 citations Open access
Semantic Scholar
TRIP13 modulates protein deubiquitination and accelerates tumor development and progression of B-cell malignancies.
Can Li, Ji-Liang Xia, Reinaldo Franqui Machin, Fang-Ping Chen +13 more
2021Journal of Clinical Investigation36 citations Open access
Semantic Scholar
NEK2 induces osteoclast differentiation and bone destruction via heparanase in multiple myeloma
M. Hao, R. Franqui-Machin, H. Xu, J. Shaughnessy +10 more
2017Leukemia30 citations Open access
Semantic Scholar
Proteasome inhibitors and bone disease
Ya-Wei Qiang, C. Heuck, J. Shaughnessy, B. Barlogie +1 more
2012Seminars in hematology (Print)30 citations Open access
Semantic Scholar
Prospective Evaluation of Operating Characteristics of Prostate Cancer Detection Biomarkers
Yuanyuan Liang, D. Ankerst, N. Ketchum, Barbara Ercole +4 more
2010Journal of Urology27 citations Open access
Semantic Scholar
CYR61/CCN1 overexpression in the myeloma microenvironment is associated with superior survival and reduced bone disease.
Sarah K. Johnson, J. Stewart, Rakesh Bam, Ping-Ping Qu +5 more
2014Blood26 citations Open access
Semantic Scholar
AKT supports the metabolic fitness of multiple myeloma cells by restricting FOXO activity
Timon A. Bloedjes, G. de Wilde, Gerarda H. Khan, T. Ashby +7 more
2022Blood Advances23 citations Open access
Semantic Scholar
Genetic Analysis of Multiple Myeloma Identifies Cytogenetic Alterations Implicated in Disease Complexity and Progression
Can Li, Erik B. Wendlandt, B. Darbro, Hong-Wei Xu +5 more
2021Cancers21 citations Open access
Semantic Scholar
Thalidomide in Total Therapy 2 Overcomes Inferior Prognosis of Myeloma with Low Expression of the Glucocorticoid Receptor Gene NR3C1
C. Heuck, J. Szymonifka, E. Hansen, J. Shaughnessy +12 more
2012Clinical Cancer Research21 citations Open access
Semantic Scholar
A Favorable BCL-2 Family Expression Profile May Explain the Increased Susceptibility of the t(11;14) Multiple Myeloma Subgroup to Single Agent Venetoclax
J. Wu, J. Ross, F. Peale, J. Shaughnessy +4 more
201610 citations Open access
Semantic Scholar
Bispecific CAR-T Cells Targeting Both BCMA and CD24: A Potentially Treatment Approach for Multiple Myeloma
Fumou Sun, Yan Cheng, B. Peng, Hong-Wei Xu +5 more
2021Blood8 citations Open access
Semantic Scholar
PHF19 inhibition as a therapeutic target in Multiple Myeloma
C. Schinke, Jordan T. Bird, Ping-Ping Qu, S. Yaccoby +16 more
2021Current Research in Translational Medicine8 citations Open access
Semantic Scholar
Gene Expression Profiling Reveals Aberrant T-cell Marker Expression on Tumor Cells of Waldenström’s Macroglobulinemia
M. Hao, B. Barlogie, G. Tricot, Lan-Ting Liu +3 more
2018Clinical Cancer Research8 citations Open access
Semantic Scholar
Ribosomal protein metallopanstimulin-1 impairs multiple myeloma CAG cells growth and inhibits fibroblast growth factor receptor 3
Yuemeng Dai, Spencer E. Pierson, Cross Dudney, Yuxin Zeng +3 more
2011Clinical Lymphoma, Myeloma & Leukemia8 citations Open access
Semantic Scholar
Under-representation of black patients with multiple myeloma in studies supporting International Myeloma Working Group guidelines.
Suhib Fahmawi, C. Schinke, S. Thanendrarajan, M. Zangari +4 more
2022Journal of Cancer Policy6 citations Open access
Semantic Scholar
SWOG S0120 Observational Trial for MGUS and Asymptomatic Multiple Myeloma (AMM): Imaging Predictors of Progression for Patients Treated At UAMS,
C. Heuck, R. Sexton, M. Dhodapkar, Qing Zhang +8 more
20115 citations
Semantic Scholar
NEK2 Inhibition Enhances the Efficacy of PD-1/PD-L1 Blockade in Multiple Myeloma
Yan Cheng, Fumou Sun, Huo-Jun Cao, Dong-Zheng Gai +7 more
2021Blood3 citations Open access
Semantic Scholar
progression following tandem stem cell transplantation MGUS to relapsed myeloma and is related to prognosis and disease detected by fluorescence in situ hybridization: Incidence increases from Frequent gain of chromosome band 1q21 in plasma cell dyscrasias
G. Tricot, B. Barlogie, J. Shaughnessy, K. Hollmig +9 more
20133 citations
Semantic Scholar
Inducible Heme Oxygenase 1 (HMOX1) Promotes Osteoblastogenesis, and Inhibits Osteoclastogenesis and Myeloma-Induced Bone Disease
Xin Li, Sarah K. Johnson, W. Ling, Sharmin Khan +4 more
20113 citations
Semantic Scholar
Thrombin-Induced PARI Signaling Pathway Modulates ß-Catenin in the Transformation of Symptomatic Myeloma Cells Into the Quiescent Phenotype,
E. Tian, S. Usmani, Yi-Ming Zhou, B. Barlogie +1 more
20113 citations
Semantic Scholar
Improved Outcome with Total Therapy 3 (TT3) In Comparison with Total Therapy 2 (TT2) Can Be Traced to GEP70-Defined High-Risk Disease with Trisomy of 1q21 and Modest but Not Marked Hyper-Activation of the Proteasome Gene PSMD4
J. Shaughnessy, Ping-Ping Qu, E. Tian, B. Nair +5 more
20103 citations
Semantic Scholar
N-Cadherin Stabilizes β-Catenin and Promotes β-Catenin/TCF Transcriptional Activation and Cell Adhesion-Mediated Drug Resistance in Multiple Myeloma
Shi-Qiao Ye, Yu Chen, Bo Hu, Hua-Yu Huang +13 more
2021Blood2 citations
Semantic Scholar
Secreted Frizzled-Related Protein-3 (sFRP3) Is Produced by Myeloma Cells and Augments Wnt3a-Induced Differentiation of Mesenchymal Stem Cells and OPG Production in Osteoblasts
Ya-Wei Qiang, Yu Chen, Bo Hu, Wei Qiang +5 more
20112 citations
Semantic Scholar
Cell Surface CXCR4 and BTK Expression Are Associated in Myeloma Cells and Osteoclast Precursors and Mediate Myeloma Cell Homing and Clonogenicity, and Osteoclastogenesis
Rakesh Bam, W. Ling, Sharmin Khan, A. Pennisi +10 more
20112 citations
Semantic Scholar
Systemically Transplanted Human Bone Marrow Mesenchymal Stem Cells Primarily Traffic to Mesenteric Lymph Nodes
Xin Li, W. Ling, Sharmin Khan, Yuping Wang +4 more
20102 citations
Semantic Scholar
Cure fractions (CF) modeled from event-free survival and complete response duration plots in total therapy (TT) trials for newly diagnosed multiple myeloma (MM).
J. Crowley, J. Shaughnessy, V. Bolejack, E. Anaissie +2 more
20102 citations
Semantic Scholar
Conflicts of interest, authorship, and disclosures in industry-related scientific publications.
R. Fonseca, P. Richardson, S. Giralt, S. Lonial +62 more
2010Mayo Clinic proceedings2 citations Open access
Semantic Scholar
Loss of Chemokine Receptor Expression and Tetraspanins Is Correlated with Extramedullary Disease In Multiple Myeloma
Z. Singh, Rebecca B. Owens, B. Nair, J. Shaughnessy +1 more
20102 citations
Semantic Scholar
Racial Differences in Spinal Cord Compression Related Hospitalizations in Patients with Multiple Myeloma
Samer al Hadidi, Deepa Dongarwar, C. Schinke, S. Thanendrarajan +3 more
2023Clinical Hematology International1 citations Open access
Semantic Scholar
OA-42 Second primary malignancies after tandem autologous hematopoietic stem cell transplantation for patients with multiple myeloma treated on earlier total therapy protocols
Samer al Hadidi, O. Ababneh, C. Schinke, S. Thanendrarajan +8 more
2023Clinical Lymphoma, Myeloma & Leukemia1 citations
Semantic Scholar
The Use and Reporting of Cytogenetics in Phase III Multiple Myeloma Clinical Trials
O. Ababneh, F. Abu Za'nouneh, C. Schinke, S. Thanendrarajan +5 more
2022Blood1 citations Open access
Semantic Scholar
Variability of Definition of High-Risk Multiple Myeloma in Phase III Clinical Trials
F. Abu Za'nouneh, O. Ababneh, C. Schinke, S. Thanendrarajan +5 more
2022Blood1 citations Open access
Semantic Scholar
Iron Trafficking through Macrophages Regulates Signaling Pathways in Myeloma
Xuelian Tan, T. Ashby, Yu-Qi Zhu, Can Li +13 more
20201 citations Open access
Semantic Scholar

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