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D. Flament · SciRah

Researcher profile · Semantic Scholar

D. Flament

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D. Flament — researcher profile on SciRah

h-index: 22
Works: 51
Citations: 1,703

Most-cited papers

Immune gene discovery by expressed sequence tags generated from hemocytes of the bacteria-challenged oyster, Crassostrea gigas.
Y. Guéguen, J. Cadoret, D. Flament, Catherine Barreau-Roumiguière +5 more
2003Gene237 citations
Semantic Scholar
An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi
G. Cohen, V. Barbe, D. Flament, M. Galperin +11 more
2003Molecular Microbiology185 citations Open access
Semantic Scholar
The endo-beta-agarases AgaA and AgaB from the marine bacterium Zobellia galactanivorans: two paralogue enzymes with different molecular organizations and catalytic behaviours.
M. Jam, D. Flament, J. Allouch, P. Potin +6 more
2005Biochemical Journal146 citations Open access
Semantic Scholar
The hyperthermophilic euryarchaeota Pyrococcus abyssi likely requires the two DNA polymerases D and B for DNA replication.
Ghislaine Henneke, D. Flament, U. Hübscher, J. Querellou +1 more
2005Journal of Molecular Biology101 citations Open access
Semantic Scholar
Characterization of a Highly Thermostable Alkaline Phosphatase from the Euryarchaeon Pyrococcus abyssi
S. Zappa, J. Rolland, D. Flament, Y. Guéguen +2 more
2001Applied and Environmental Microbiology101 citations Open access
Semantic Scholar
Characterization of two DNA polymerases from the hyperthermophilic euryarchaeon Pyrococcus abyssi.
Y. Guéguen, J. Rolland, O. Lecompte, Philippe Azam +4 more
2001European Journal of Biochemistry76 citations Open access
Semantic Scholar
Analysis of the First Genome of a Hyperthermophilic Marine Virus-Like Particle, PAV1, Isolated from Pyrococcus abyssi
C. Geslin, M. Gaillard, D. Flament, K. Rouault +3 more
2007Journal of Bacteriology69 citations Open access
Semantic Scholar
Alpha-Agarases Define a New Family of Glycoside Hydrolases, Distinct from Beta-Agarase Families
D. Flament, T. Barbeyron, M. Jam, P. Potin +3 more
2007Applied and Environmental Microbiology64 citations Open access
Semantic Scholar
MARINE-EXPRESS: taking advantage of high throughput cloning and expression strategies for the post-genomic analysis of marine organisms
A. Groisillier, Cécile Hervé, A. Jeudy, E. Rebuffet +11 more
2010Microbial Cell Factories63 citations Open access
Semantic Scholar
Structural insights into a new homodimeric self‐activated GTPase family
S. Gras, V. Chaumont, Bernard Fernandez, P. Carpentier +8 more
2007EMBO Reports56 citations Open access
Semantic Scholar
A novel proteomic approach identifies new interaction partners for proliferating cell nuclear antigen.
L. Meslet-Cladière, Cédric A. Norais, Joëlle Kuhn, Julien Briffotaux +5 more
2007Journal of Molecular Biology55 citations Open access
Semantic Scholar
The heterodimeric primase from the euryarchaeon Pyrococcus abyssi: a multifunctional enzyme for initiation and repair?
M. Le Breton, Ghislaine Henneke, Cédric A. Norais, D. Flament +3 more
2007Journal of Molecular Biology52 citations Open access
Semantic Scholar
An Extended Network of Genomic Maintenance in the Archaeon Pyrococcus abyssi Highlights Unexpected Associations between Eucaryotic Homologs
Pierre-François Pluchon, T. Fouqueau, C. Crezé, Sébastien Laurent +9 more
2013PLoS ONE47 citations Open access
Semantic Scholar
Genetic Manipulations of the Hyperthermophilic Piezophilic Archaeon Thermococcus barophilus
Axel Thiel, G. Michoud, Y. Moalic, D. Flament +1 more
2014Applied and Environmental Microbiology46 citations Open access
Semantic Scholar
DNA polymerase switching on homotrimeric PCNA at the replication fork of the euryarchaea Pyrococcus abyssi.
C. Rouillon, Ghislaine Henneke, D. Flament, J. Querellou +1 more
2007Journal of Molecular Biology36 citations Open access
Semantic Scholar
Structure and function of a novel endonuclease acting on branched DNA substrates
B. Ren, Joëlle Kühn, L. Meslet-Cladière, Julien Briffotaux +5 more
2009EMBO Journal35 citations Open access
Semantic Scholar
Structure and function of a novel endonuclease acting on branched DNA substrates.
C. Crezé, Roxane Lestini, Joëlle Kühn, Alessio Ligabue +4 more
2011Biochemical Society Transactions34 citations Open access
Semantic Scholar
Binding to PCNA in Euryarchaeal DNA Replication requires two PIP motifs for DNA polymerase D and one PIP motif for DNA polymerase B.
Benoît Castrec, C. Rouillon, Ghislaine Henneke, D. Flament +2 more
2009Journal of Molecular Biology30 citations Open access
Semantic Scholar
Replication factor C from the hyperthermophilic archaeon Pyrococcus abyssi does not need ATP hydrolysis for clamp-loading and contains a functionally conserved RFC PCNA-binding domain.
Ghislaine Henneke, Y. Guéguen, D. Flament, Philippe Azam +4 more
2002Journal of Molecular Biology29 citations Open access
Semantic Scholar
Development of an Effective 6-Methylpurine Counterselection Marker for Genetic Manipulation in Thermococcus barophilus
Tiphaine Birien, Axel Thiel, Ghislaine Henneke, D. Flament +2 more
2018Genes28 citations Open access
Semantic Scholar
Expression, purification, crystallization and preliminary X-ray analysis of the iota-carrageenase from Alteromonas fortis.
G. Michel, D. Flament, T. Barbeyron, Thierry Vernet +2 more
2000Acta Crystallographica Section D: Biological Crystallography27 citations
Semantic Scholar
Genetic elements of Thermococcales.
D. Prieur, G. Erauso, C. Geslin, S. Lucas +7 more
2004Biochemical Society Transactions24 citations
Semantic Scholar
Modulation of the Pyrococcus abyssi NucS Endonuclease Activity by Replication Clamp at Functional and Structural Levels*
C. Crezé, Alessio Ligabue, Sébastien Laurent, Roxane Lestini +6 more
2012Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Expression, purification, crystallization and preliminary x-ray analysis of the kappa-carrageenase from Pseudoalteromonas carrageenovora.
G. Michel, T. Barbeyron, D. Flament, Thierry Vernet +2 more
1999Acta Crystallographica Section D: Biological Crystallography21 citations
Semantic Scholar
DNA-binding mechanism and evolution of replication protein A
C. Madru, M. Martínez-Carranza, Sébastien Laurent, A. Alberti +10 more
2022bioRxiv19 citations Open access
Semantic Scholar
RNA processing machineries in Archaea: the 5′-3′ exoribonuclease aRNase J of the β-CASP family is engaged specifically with the helicase ASH-Ski2 and the 3′-5′ exoribonucleolytic RNA exosome machinery
D. Phùng, Clarisse Etienne, Manon Batista, Petra Langendijk-Genevaux +9 more
2020Nucleic Acids Research19 citations Open access
Semantic Scholar
Role of RadA and DNA Polymerases in Recombination-Associated DNA Synthesis in Hyperthermophilic Archaea
G. Hogrel, Yang Lu, Nicolas Alexandre, Audrey Bossé +4 more
2020Biomolecules14 citations Open access
Semantic Scholar
Modelization of the regulation of protein synthesis following fertilization in sea urchin shows requirement of two processes: a destabilization of eIF4E:4E-BP complex and a great stimulation of the 4E-BP-degradation mechanism, both rapamycin-sensitive
Sébastien Laurent, A. Richard, O. Mulner-lorillon, J. Morales +7 more
2014Frontiers in Genetics13 citations Open access
Semantic Scholar
The glycine-rich motif of Pyrococcus abyssi DNA polymerase D is critical for protein stability.
Benoît Castrec, Sébastien Laurent, Ghislaine Henneke, D. Flament +1 more
2010Journal of Molecular Biology13 citations
Semantic Scholar
Physical and functional interplay between PCNA DNA clamp and Mre11–Rad50 complex from the archaeon Pyrococcus furiosus
G. Hogrel, Yang Lu, Sébastien Laurent, Etienne Henry +7 more
2018Nucleic Acids Research11 citations Open access
Semantic Scholar
The sulphated-galactan hydrolases, agarases and carrageenases : structural biology and molecular evolution
T. Barbeyron, D. Flament, G. Michel, P. Potin +1 more
20018 citations
Semantic Scholar
Comment on "The first description of an archaeal hemicellulase: the xylanase from Thermococcus zilligii strain AN1": evidence that the unique N-terminal sequence proposed comes from a maltodextrin phosphorylase
J. Rolland, Y. Guéguen, D. Flament, Y. Pouliquen +2 more
2002Extremophiles7 citations
Semantic Scholar
Phylogenetic Diversity of Lhr Proteins and Biochemical Activities of the Thermococcales aLhr2 DNA/RNA Helicase
Mirna Hajj, Petra Langendijk-Genevaux, Manon Batista, Y. Quentin +8 more
2021Biomolecules6 citations Open access
Semantic Scholar
11 Deep-sea Thermococcales and their Genetic Elements: Plasmids and Viruses
D. Prieur, G. Erauso, D. Flament, M. Gaillard +5 more
20066 citations
Semantic Scholar
DNA Polymerization in Icy Moon Abyssal Pressure Conditions
Lorenzo Carré, Ghislaine Henneke, Etienne Henry, D. Flament +2 more
2023Astrobiology2 citations Open access
Semantic Scholar
Phylogenetic Diversity of Lhr Proteins and Miochemical Activities of the Thermococcales aLhr2 DNA/RNA Helicase
Mirna Hajj, Petra Langendijk-Genevaux, Manon Batista, Y. Quentin +7 more
20211 citations Open access
Semantic Scholar
Crystal Structure of PAV1-137: A Protein from the Virus PAV1 That Infects Pyrococcus abyssi
N. Leulliot, S. Quevillon-Cheruel, M. Graille, C. Geslin +3 more
2013Archaea1 citations Open access
Semantic Scholar
Characterization of a small tRNA‐binding protein that interacts with the archaeal proteasome complex
G. Hogrel, Laura Mariño-Puertas, Sébastien Laurent, Ziad Ibrahim +9 more
2022Molecular Microbiology0 citations Open access
Semantic Scholar
Role of Ori in Thermococcus barophilus
Y. Moalic, R. Catchpole, Elodie C. Leroy, Logan Mc Teer +7 more
2021bioRxiv0 citations Open access
Semantic Scholar
RNA processing machineries in Archaea: the 5 -3 exoribonuclease aRNase J of the (cid:2) -CASP family is engaged speciﬁcally with the helicase ASH-Ski2 and the 3 (cid:2) -5 (cid:2) exoribonucleolytic RNA exosome machinery
D. Phùng, Clarisse Etienne, Manon Batista, Petra Langendijk-Genevaux +9 more
20200 citations
Semantic Scholar
RNA processing machineries in Archaea: the 5’-3’ exoribonuclease aRNase J of the β-CASP family is engaged specifically with the helicase ASH-Ski2 and the 3’-5’ exoribonucleolytic RNA exosome machinery
D. Phùng, Clarisse Etienne, Manon Batista, Petra Langendijk-Genevaux +8 more
2019bioRxiv0 citations Open access
Semantic Scholar
Real-Time Fluorescence Assays to Monitor DNA Polymerase Activities
Etienne Henry, Ghislaine Henneke, D. Flament
20170 citations Open access
Semantic Scholar
Interactions entre composants de la maintenance génomique chez Archaea hyperthermophiles : étude des associations entre PCNA et le complexe Mre11-Rad50 et entre les hélicases MCM et XPD
Gaëlle Hogrel, G. Legube, P. Forterre, Bruno Franzetti +7 more
20150 citations
Semantic Scholar
Archaeal DNA Repair Nucleases
Roxanne Lestini, C. Crezé, D. Flament, H. Myllykallio +1 more
20110 citations Open access
Semantic Scholar
Alpha-agarases define a new family of glycoside hydrolases , distinct from 3 beta-agarase families 4 5
D. Flament, T. Barbeyron, M. Jam, Mirjam Philippe Potin +2 more
20110 citations
Semantic Scholar
crystal structure of a repair endonuclease from Pyrococcus abyssi
B. Ren, Joëlle Kuhn, L. Meslet-Cladière, Julien Briffotaux +5 more
20090 citations
Semantic Scholar
Properties and roles of DNA polymerases of Pyrococcus abyssi
J. Querellou, Ghislaine Henneke, D. Flament, U. Hübscher +1 more
20070 citations
Semantic Scholar
How to degrade sulfated galactans: the structure of κ- and ι-carrageenases
G. Michel, L. Chantalat, E. Fanchon, D. Flament +5 more
20000 citations Open access
Semantic Scholar
Genes encoding β-agarases and their use in the production of enzymes for the biodegradation of agar
D. Flament, T. Barbeyron, J. Yvin, P. Potin +1 more
19990 citations
Semantic Scholar
Microbial degradation of sulfated galactans. Toward novel utilizations of red algae polysaccharides
B. Kloareg, T. Barbeyron, D. Flament, G. Michel +3 more
19980 citations
Semantic Scholar

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