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N. Gruel · SciRah

Researcher profile · Semantic Scholar

N. Gruel

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N. Gruel — researcher profile on SciRah

h-index: 27
Works: 70
Citations: 2,532

Most-cited papers

JUN oncogene amplification and overexpression block adipocytic differentiation in highly aggressive sarcomas.
O. Mariani, Caroline Brennetot, J. Coindre, N. Gruel +4 more
2007Cancer Cell209 citations Open access
Semantic Scholar
Identification of typical medullary breast carcinoma as a genomic sub-group of basal-like carcinomas, a heterogeneous new molecular entity
A. Vincent-Salomon, N. Gruel, C. Lucchesi, G. MacGrogan +15 more
2007Breast Cancer Research184 citations Open access
Semantic Scholar
High frequency of TP53 mutation in BRCA1 and sporadic basal-like carcinomas but not in BRCA1 luminal breast tumors.
Elodie Manié, A. Vincent-Salomon, J. Lehmann-Che, G. Pierron +12 more
2009Cancer Research171 citations Open access
Semantic Scholar
Integrated Genomic and Transcriptomic Analysis of Ductal Carcinoma In situ of the Breast
A. Vincent-Salomon, C. Lucchesi, N. Gruel, V. Raynal +10 more
2008Clinical Cancer Research168 citations Open access
Semantic Scholar
VAMP: Visualization and analysis of array-CGH, transcriptome and other molecular profiles
P. La Rosa, E. Viara, P. Hupé, G. Pierron +18 more
2006Bioinform.116 citations Open access
Semantic Scholar
Characterization of the recurrent 8p11-12 amplicon identifies PPAPDC1B, a phosphatase protein, as a new therapeutic target in breast cancer.
I. Bernard-Pierrot, N. Gruel, N. Stransky, A. Vincent-Salomon +6 more
2008Cancer Research104 citations Open access
Semantic Scholar
CXCR6 expressing T cells: Functions and role in the control of tumors
Nesrine Mabrouk, Thi-Anh-Thuy Tran, I. Sam, I. Pourmir +7 more
2022Frontiers in Immunology96 citations Open access
Semantic Scholar
Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution.
M. Aynaud, O. Mirabeau, N. Gruel, S. Grossetête +18 more
2020Cell Reports94 citations Open access
Semantic Scholar
8p22 MTUS1 Gene Product ATIP3 Is a Novel Anti-Mitotic Protein Underexpressed in Invasive Breast Carcinoma of Poor Prognosis
S. Rodrigues-Ferreira, A. di Tommaso, Ariane Dimitrov, S. Cazaubon +13 more
2009PLoS ONE94 citations Open access
Semantic Scholar
A prognostic DNA signature for T1T2 node‐negative breast cancer patients
É. Gravier, G. Pierron, A. Vincent-Salomon, N. Gruel +12 more
2010Genes, Chromosomes and Cancer91 citations
Semantic Scholar
Restoration of transcriptional activity of p53 mutants in human tumour cells by intracellular expression of anti-p53 single chain Fv fragments
C. D. de Fromentel, N. Gruel, C. Venot, L. Debussche +5 more
1999Oncogene86 citations
Semantic Scholar
Impaired PRC2 activity promotes transcriptional instability and favors breast tumorigenesis
M. Wassef, Verónica Rodilla, Aurélie Teissandier, Bruno Zeitouni +19 more
2015Genes & Development83 citations Open access
Semantic Scholar
CXCR6 deficiency impairs cancer vaccine efficacy and CD8+ resident memory T-cell recruitment in head and neck and lung tumors
S. Karaki, C. Blanc, Thi Tran, I. Galy-Fauroux +18 more
2021Journal for ImmunoTherapy of Cancer75 citations Open access
Semantic Scholar
Reversible transitions between noradrenergic and mesenchymal tumor identities define cell plasticity in neuroblastoma
C. Thirant, A. Peltier, S. Durand, Amira Kramdi +28 more
2023Nature Communications73 citations Open access
Semantic Scholar
Lobular invasive carcinoma of the breast is a molecular entity distinct from luminal invasive ductal carcinoma.
N. Gruel, C. Lucchesi, V. Raynal, M. Rodrigues +8 more
2010European Journal of Cancer70 citations
Semantic Scholar
Gene expression profiling of 1p35–36 genes in neuroblastoma
I. Janoueix-Lerosey, E. Novikov, M. Monteiro, N. Gruel +4 more
2004Oncogene70 citations Open access
Semantic Scholar
ESR1 gene amplification in breast cancer: a common phenomenon?
A. Vincent-Salomon, V. Raynal, C. Lucchesi, N. Gruel +1 more
2008Nature Genetics67 citations
Semantic Scholar
ATIP3, a novel prognostic marker of breast cancer patient survival, limits cancer cell migration and slows metastatic progression by regulating microtubule dynamics.
Angie Molina, Lauriane Vélot, Lydia Ghouinem, M. Abdelkarim +18 more
2013Cancer Research59 citations Open access
Semantic Scholar
A siRNA screen identifies RAD21, EIF3H, CHRAC1 and TANC2 as driver genes within the 8q23, 8q24.3 and 17q23 amplicons in breast cancer with effects on cell growth, survival and transformation.
S. Mahmood, N. Gruel, Elodie Chapeaublanc, Aurianne Lescure +11 more
2014Carcinogenesis58 citations
Semantic Scholar
Single-cell transcriptomics reveals shared immunosuppressive landscapes of mouse and human neuroblastoma
Ana Costa, C. Thirant, Amira Kramdi, C. Pierre-Eugene +25 more
2022Journal for ImmunoTherapy of Cancer54 citations Open access
Semantic Scholar
Transcriptional programs define intratumoral heterogeneity of Ewing sarcoma at single cell resolution
M. Aynaud, O. Mirabeau, N. Gruel, S. Grossetête +17 more
2019bioRxiv52 citations Open access
Semantic Scholar
Polarity gene alterations in pure invasive micropapillary carcinomas of the breast
N. Gruel, Vanessa Benhamo, J. Bhalshankar, T. Popova +9 more
2014Breast Cancer Research49 citations Open access
Semantic Scholar
A New Set of Monoclonal Antibodies Against Human FcγRII (CD32) and FcγRIII (CD16): Characterization and Use in Various Assays
F. Vely, N. Gruel, J. Moncuit, O. Cochet +6 more
199742 citations
Semantic Scholar
PPAPDC1B and WHSC1L1 are common drivers of the 8p11-12 amplicon, not only in breast tumors but also in pancreatic adenocarcinomas and lung tumors.
S. Mahmood, N. Gruel, R. Nicolle, Elodie Chapeaublanc +3 more
2013American Journal of Pathology38 citations Open access
Semantic Scholar
Oncogenic chimeric transcription factors drive tumor-specific transcription, processing, and translation of silent genomic regions.
J. Vibert, O. Saulnier, Céline Collin, Floriane Petit +25 more
2022Molecules and Cells34 citations Open access
Semantic Scholar
Identification of tissue of origin and guided therapeutic applications in cancers of unknown primary using deep learning and RNA sequencing (TransCUPtomics).
J. Vibert, G. Pierron, Camille Benoist, N. Gruel +10 more
2021Journal of Molecular Diagnostics30 citations Open access
Semantic Scholar
Cellular origin and clonal evolution of human dedifferentiated liposarcoma
N. Gruel, C. Quignot, L. Lesage, S. El Zein +20 more
2024Nature Communications28 citations Open access
Semantic Scholar
Plasma CD27, a surrogate of the intratumoral CD27-CD70 interaction, correlates with immunotherapy resistance in renal cell carcinoma.
N. Benhamouda, I. Sam, N. Epaillard, A. Gey +27 more
2022Clinical Cancer Research26 citations Open access
Semantic Scholar
Single-cell multiomics profiling reveals heterogeneous transcriptional programs and microenvironment in DSRCTs
C. Hénon, J. Vibert, Thomas Eychenne, N. Gruel +23 more
2024Cell Reports Medicine25 citations Open access
Semantic Scholar
Genomic Instability: A Stronger Prognostic Marker Than Proliferation for Early Stage Luminal Breast Carcinomas
A. Vincent-Salomon, Vanessa Benhamo, É. Gravier, G. Rigaill +12 more
2013PLoS ONE24 citations Open access
Semantic Scholar
A new set of monoclonal antibodies against human Fc gamma RII (CD32) and Fc gamma RIII (CD16): characterization and use in various assays.
F. Vely, N. Gruel, J. Moncuit, O. Cochet +6 more
1997Hybridoma18 citations
Semantic Scholar
New developments in the pathology and molecular biology of retroperitoneal sarcomas.
S. Watson, N. Gruel, F. Le Loarer
2022European Journal of Surgical Oncology16 citations Open access
Semantic Scholar
High Ki67 expression is a risk marker of invasive relapse for classical lobular carcinoma in situ patients.
A. Vincent-Salomon, D. Hajage, A. Rouquette, Aurélie Cédenot +6 more
2012Breast16 citations Open access
Semantic Scholar
Interplay between intrinsic reprogramming potential and microenvironment controls neuroblastoma cell plasticity and identity
C. Thirant, A. Peltier, S. Durand, Amira Kramdi +26 more
2021bioRxiv15 citations Open access
Semantic Scholar
Medullary Breast Carcinoma, a Triple-Negative Breast Cancer Associated with BCLG Overexpression.
Pierre Romero, Vanessa Benhamo, Gabrielle Deniziaut, L. Fuhrmann +17 more
2018American Journal of Pathology15 citations Open access
Semantic Scholar
First description of a sporadic breast cancer in a woman with BRCA1 germline mutation
E. Curtit, Vanessa Benhamo, N. Gruel, T. Popova +7 more
2015OncoTarget10 citations Open access
Semantic Scholar
MDM4 amplification in atypical lipomatous tumors/well‐differentiated liposarcoma: Private event or alternative oncogenic mechanism?
N. Gruel, S. El Zein, D. Tzanis, Nayla Nicolas +10 more
2023Genes, Chromosomes and Cancer9 citations Open access
Semantic Scholar
Bypassing tumor-specific and bispecific antibodies: triggering of antitumor immunity by expression of anti-FcγR scFv on cancer cell surface
N. Gruel, Wolf H. Fridman, J. L. Teillaud
2001Gene Therapy9 citations
Semantic Scholar
A metabolic crosstalk between liposarcoma and muscle sustains tumor growth
Gabrielle Manteaux, A. Amsel, Blanche Riquier-Morcant, Jaime Prieto Romero +18 more
2023bioRxiv7 citations Open access
Semantic Scholar
Mild dyslipidemia accelerates tumorigenesis through expansion of Ly6Chi monocytes and differentiation to pro-angiogenic myeloid cells
Thi Tran, J. Lavillegrand, Cédric Lerévérend, B. Esposito +21 more
2022Nature Communications7 citations Open access
Semantic Scholar
Generation of scFv from a phage display mini-library derived from tumor-infiltrating B-cells.
N. Gruel, B. Kotlán, M. Beuzard, J. Teillaud
2002Methods in molecular biology7 citations
Semantic Scholar
A tumor specific single chain antibody dependent gene expression system
Marie-Noëlle Mary, C. Venot, C. D. de Fromentel, L. Debussche +7 more
1999Oncogene7 citations
Semantic Scholar
Metastatic renal cell carcinoma with occult primary: a multicenter prospective cohort
N. Jacquin, R. Flippot, J. Masliah-Planchon, G. Grisay +20 more
2024npj Precision Oncology5 citations Open access
Semantic Scholar
Structurally different anthracyclines provoke different effects on cell cycle and tumor B cell differentiation.
J. Teillaud, N. Gruel, Janine Moncuit, Z. Mishal +3 more
1998Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie5 citations Open access
Semantic Scholar
Generation of functional scFv intrabodies for triggering anti-tumor immunity.
E. Bonnin, N. Gruel, S. Moutel, Adriana R. Mantegazza +3 more
2004Methods4 citations
Semantic Scholar
PURIFICATION OF SOLUBLE RECOMBINANT HUMAN FcγRII (CD32)
N. Gruel, J. Chapiro, Wolf H. Fridman, J. L. Teillaud
20014 citations
Semantic Scholar
Intracellular Targeting of Oncogenes: A Novel Approach for Cancer Therapy
O. Cochet, I. Delumeau, M. Kenigsberg, N. Gruel +4 more
19984 citations
Semantic Scholar
Abstract 87: Micropapillary breast carcinoma is characterized by deregulation of genes involved in cell division control
N. Gruel, Vanessa Benhamo, T. Popova, A. Gauthier +17 more
20123 citations
Semantic Scholar
Purification of soluble recombinant human FcgammaRII (CD32).
N. Gruel, J. Chapiro, W. Fridman, J. Teillaud
2001Preparative Biochemistry & Biotechnology3 citations
Semantic Scholar
Neoadjuvant Everolimus for Adult Giant Mesenteric Cystic Lymphangioma with mTOR Pathway Activation.
S. El Zein, N. Gruel, S. Bonvalot, O. Mir +1 more
2021The Oncologist2 citations Open access
Semantic Scholar

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