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M. Gorovsky · SciRah

Researcher profile · Semantic Scholar

M. Gorovsky

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M. Gorovsky — researcher profile on SciRah

h-index: 63
Works: 180
Citations: 14K

Most-cited papers

Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote
J. Eisen, R. S. Coyne, Martin Wu, Dongying Wu +49 more
2006PLoS Biology770 citations Open access
Semantic Scholar
Phosphorylation of histone H3 is required for proper chromosome condensation and segregation.
Yi Wei, Lan-Lan Yu, J. Bowen, M. Gorovsky +1 more
1999Cell769 citations Open access
Semantic Scholar
Analysis of a piwi-related gene implicates small RNAs in genome rearrangement in tetrahymena.
Kazufumi Mochizuki, N. Fine, T. Fujisawa, M. Gorovsky
2002Cell635 citations Open access
Semantic Scholar
Phosphorylation of histone H3 at serine 10 is correlated with chromosome condensation during mitosis and meiosis in Tetrahymena.
Yi Wei, C. Mizzen, Richard G. Cook, M. Gorovsky +1 more
1998Proceedings of the National Academy of Sciences of the United States of America458 citations Open access
Semantic Scholar
Linker histones are not essential and affect chromatin condensation in vivo.
X. Shen, L. Yu, J. Weir, M. Gorovsky
1995Cell330 citations
Semantic Scholar
A unified phylogeny-based nomenclature for histone variants
P. Talbert, K. Ahmad, G. Almouzni, J. Ausió +38 more
2012Epigenetics & Chromatin328 citations Open access
Semantic Scholar
Linker histone H1 regulates specific gene expression but not global transcription in vivo.
Xue-Tong Shen, M. Gorovsky
1996Cell322 citations Open access
Semantic Scholar
Germline and somatic transformation of mating Tetrahymena thermophila by particle bombardment.
D. Cassidy-Hanley, J. Bowen, John H. Lee, E. Cole +4 more
1997Genetics291 citations
Semantic Scholar
A robust inducible-repressible promoter greatly facilitates gene knockouts, conditional expression, and overexpression of homologous and heterologous genes in Tetrahymena thermophila
Yuhua Shang, Xiao-Yuan Song, J. Bowen, Robert Corstanje +3 more
2002Proceedings of the National Academy of Sciences of the United States of America251 citations Open access
Semantic Scholar
A Dicer-like protein in Tetrahymena has distinct functions in genome rearrangement, chromosome segregation, and meiotic prophase.
Kazufumi Mochizuki, M. Gorovsky
2005Genes & Development244 citations Open access
Semantic Scholar
Phylogenetic analysis of the core histones H2A, H2B, H3, and H4.
T. Thatcher, M. Gorovsky
1994Nucleic Acids Research237 citations Open access
Semantic Scholar
Small RNAs in genome rearrangement in Tetrahymena.
Kazufumi Mochizuki, M. Gorovsky
2004Current Opinion in Genetics and Development232 citations
Semantic Scholar
Microarray Analyses of Gene Expression during the Tetrahymena thermophila Life Cycle
W. Miao, Jie Xiong, J. Bowen, Wei Wang +6 more
2009PLoS ONE197 citations Open access
Semantic Scholar
Conjugation-specific small RNAs in Tetrahymena have predicted properties of scan (scn) RNAs involved in genome rearrangement.
Kazufumi Mochizuki, M. Gorovsky
2004Genes & Development180 citations Open access
Semantic Scholar
Histone H3 lysine 9 methylation is required for DNA elimination in developing macronuclei in Tetrahymena.
Yi-Fan Liu, Kazufumi Mochizuki, M. Gorovsky
2004Proceedings of the National Academy of Sciences of the United States of America178 citations Open access
Semantic Scholar
Mapping the 5' and 3' ends of Tetrahymena thermophila mRNAs using RNA ligase mediated amplification of cDNA ends (RLM-RACE).
Xiu-Wen Liu, M. Gorovsky
1993Nucleic Acids Research170 citations Open access
Semantic Scholar
High frequency vector-mediated transformation and gene replacement in Tetrahymena.
J. Gaertig, Long Gu, Bing Hai, M. Gorovsky
1994Nucleic Acids Research169 citations Open access
Semantic Scholar
Tetrahymena thermophila.
K. Collins, M. Gorovsky
2005Current Biology150 citations Open access
Semantic Scholar
Acetylation of lysine 40 in alpha-tubulin is not essential in Tetrahymena thermophila
Jacek Gaertig, M. A. Cruz, J. Bowen, Long Gu +2 more
1995Journal of Cell Biology146 citations Open access
Semantic Scholar
Study of an RNA helicase implicates small RNA-noncoding RNA interactions in programmed DNA elimination in Tetrahymena.
L. Aronica, J. Bednenko, Tomoko Noto, Leroi V. De Souza +5 more
2008Genes & Development144 citations Open access
Semantic Scholar
Histone H2A.Z has a conserved function that is distinct from that of the major H2A sequence variants.
J. D. Jackson, M. Gorovsky
2000Nucleic Acids Research142 citations Open access
Semantic Scholar
Phosphorylation of linker histone H1 regulates gene expression in vivo by mimicking H1 removal.
Y. Dou, C. Mizzen, Marc Abrams, C. Allis +1 more
1999Molecules and Cells140 citations Open access
Semantic Scholar
Polyglycylation of Tubulin Is Essential and Affects Cell Motility and Division in Tetrahymena thermophila
L. Xia, Bing Hai, Yan Gao, D. Burnette +6 more
2000Journal of Cell Biology136 citations Open access
Semantic Scholar
A simplified formaldehyde fixation and immunoprecipitation technique for studying protein-DNA interactions.
P. Dedon, J. A. Soults, C. Allis, M. Gorovsky
1991Analytical Biochemistry132 citations Open access
Semantic Scholar
Histone H2A.Z acetylation modulates an essential charge patch.
Qinghu Ren, M. Gorovsky
2001Molecules and Cells129 citations Open access
Semantic Scholar
Tetrahymena thermophila contains a conventional γ-tubulin that is differentially required for the maintenance of different microtubule-organizing centers
Yuhua Shang, Bing Li, M. Gorovsky
2002Journal of Cell Biology127 citations Open access
Semantic Scholar
Temporal and spatial association of histone H2A variant hv1 with transcriptionally competent chromatin during nuclear development in Tetrahymena thermophila.
Laurie A. Stargell, J. Bowen, C. A. Dadd, Peter C. Dedon +4 more
1993Genes & Development126 citations Open access
Semantic Scholar
Efficient mass transformation of Tetrahymena thermophila by electroporation of conjugants.
Jacek Gaertig, M. Gorovsky
1992Proceedings of the National Academy of Sciences of the United States of America116 citations Open access
Semantic Scholar
Phosphorylation of linker histone H1 regulates gene expression in vivo by creating a charge patch.
Yali Dou, M. Gorovsky
2000Molecules and Cells106 citations Open access
Semantic Scholar
Glutamylation on α-Tubulin Is Not Essential but Affects the Assembly and Functions of a Subset of Microtubules in Tetrahymena thermophila
Dorota Wloga, Krzysztof Rogowski, Neeraj Sharma, J. van Dijk +9 more
2008Eukaryotic Cell105 citations Open access
Semantic Scholar
Electroporation-mediated replacement of a positively and negatively selectable beta-tubulin gene in Tetrahymena thermophila.
Jacek Gaertig, Thomas H. Thatcher, Long Gu, M. Gorovsky
1994Proceedings of the National Academy of Sciences of the United States of America97 citations Open access
Semantic Scholar
Conserved mechanism of tRNA splicing in eukaryotes
M. Zillmann, M. Gorovsky, E. Phizicky
1991Molecular and Cellular Biology96 citations Open access
Semantic Scholar
Phosphorylation and an ATP-dependent process increase the dynamic exchange of H1 in chromatin
Y. Dou, J. Bowen, Yi-Fan Liu, M. Gorovsky
2002Journal of Cell Biology94 citations Open access
Semantic Scholar
The Tetrahymena Argonaute-binding protein Giw1p directs a mature Argonaute-siRNA complex to the nucleus
Tomoko Noto, Henriette Kurth, Kensuke Kataoka, L. Aronica +5 more
2010Cell91 citations Open access
Semantic Scholar
Comparison of the sequences of macro- and micronuclear DNA of Tetrahymena pyriformis
M. Yao, M. Gorovsky
2004Chromosoma90 citations
Semantic Scholar
Genome-Scale Analysis of Programmed DNA Elimination Sites in Tetrahymena thermophila
J. Fass, Nikhil Joshi, Mary T. Couvillion, J. Bowen +9 more
2011G3: Genes, Genomes, Genetics82 citations Open access
Semantic Scholar
Germ-line knockout heterokaryons of an essential alpha-tubulin gene enable high-frequency gene replacement and a test of gene transfer from somatic to germ-line nuclei in Tetrahymena thermophila.
Bing Hai, M. Gorovsky
1997Proceedings of the National Academy of Sciences of the United States of America80 citations Open access
Semantic Scholar
Perspectives on tubulin isotype function and evolution based on the observation that Tetrahymena thermophila microtubules contain a single α‐ and β‐tubulin
J. Gaertig, T. Thatcher, K. McGrath, R. Callahan +1 more
199378 citations
Semantic Scholar
Deposition and Function of Histone H3 Variants in Tetrahymena thermophila
Bo-Wen Cui, Yi-Fan Liu, M. Gorovsky
2006Molecular and Cellular Biology77 citations Open access
Semantic Scholar
Formaldehyde cross-linking and immunoprecipitation demonstrate developmental changes in H1 association with transcriptionally active genes
P. C. Dedon, J. A. Soults, C. Allis, M. Gorovsky
1991Molecular and Cellular Biology69 citations Open access
Semantic Scholar
A Novel Chromodomain Protein, Pdd3p, Associates with Internal Eliminated Sequences during Macronuclear Development inTetrahymena thermophila
M. Nikiforov, M. Gorovsky, C. Allis
2000Molecular and Cellular Biology64 citations Open access
Semantic Scholar
Tetrahymena IFT122A is not essential for cilia assembly but plays a role in returning IFT proteins from the ciliary tip to the cell body
Che-Chia Tsao, M. Gorovsky
2008Journal of Cell Science63 citations
Semantic Scholar
Both Carboxy-Terminal Tails of α- and β-Tubulin Are Essential, but Either One Will Suffice
J. Duan, M. Gorovsky
200263 citations Open access
Semantic Scholar
Excision of micronuclear-specific DNA requires parental expression of pdd2p and occurs independently from DNA replication in Tetrahymena thermophila.
Mikhail A. Nikiforov, J. F. Smothers, M. Gorovsky, C. Allis
1999Genes & Development63 citations Open access
Semantic Scholar
Cell context-specific effects of the beta-tubulin glycylation domain on assembly and size of microtubular organelles.
Rupal Thazhath, M. Jerka-Dziadosz, J. Duan, Dorota Wloga +3 more
2004Molecular Biology of the Cell61 citations Open access
Semantic Scholar
Knockout heterokaryons enable facile mutagenic analysis of essential genes in Tetrahymena.
Bing Hai, J. Gaertig, M. Gorovsky
2000Methods in Cell Biology60 citations
Semantic Scholar
Different effects of Tetrahymena IFT172 domains on anterograde and retrograde intraflagellar transport.
Che-Chia Tsao, M. Gorovsky
2008Molecular Biology of the Cell58 citations Open access
Semantic Scholar
A likely histone H2A.F/Z variant in Saccharomyces cerevisiae.
John d. Jackson, Vincenzo T. Falciano, M. Gorovsky
1996TIBS -Trends in Biochemical Sciences. Regular ed57 citations Open access
Semantic Scholar
Small-RNA-Mediated Genome-wide trans-Recognition Network in Tetrahymena DNA Elimination
Tomoko Noto, Kensuke Kataoka, J. Suhren, A. Hayashi +3 more
2015Molecules and Cells55 citations Open access
Semantic Scholar
RNA Polymerase II Localizes in Tetrahymena thermophila Meiotic Micronuclei When Micronuclear Transcription Associated with Genome Rearrangement Occurs
Kazufumi Mochizuki, M. Gorovsky
2004Eukaryotic Cell53 citations Open access
Semantic Scholar

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