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H. Sakagami · SciRah

Researcher profile · Semantic Scholar

H. Sakagami

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H. Sakagami — researcher profile on SciRah

h-index: 52
Works: 608
Citations: 15K

Most-cited papers

ACE2: The Key Molecule for Understanding the Pathophysiology of Severe and Critical Conditions of COVID-19: Demon or Angel?
Li Xiao, H. Sakagami, N. Miwa
2020Viruses169 citations Open access
Semantic Scholar
New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors.
H. Gul, C. Yamali, H. Sakagami, A. Angeli +5 more
2018Bioorganic chemistry (Print)131 citations Open access
Semantic Scholar
Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity.
Dilan Ozmen Ozgun, H. Gul, C. Yamali, H. Sakagami +3 more
2019Bioorganic chemistry (Print)125 citations
Semantic Scholar
Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors.
M. Tuğrak, H. Gul, K. Bandow, H. Sakagami +3 more
2019Bioorganic chemistry (Print)67 citations
Semantic Scholar
New azafluorenones with cytotoxic and carbonic anhydrase inhibitory properties: 2-Aryl-4-(4-hydroxyphenyl)-5H-indeno[1,2-b]pyridin-5-ones.
M. Tuğrak, Halise Inci Gul, H. Sakagami, I. Gulcin +1 more
2018Bioorganic chemistry (Print)62 citations
Semantic Scholar
New phenolic Mannich bases with piperazines and their bioactivities.
H. Gul, M. Tuğrak, M. Gul, Sertac Mazlumoglu +3 more
2019Bioorganic chemistry (Print)54 citations
Semantic Scholar
Three new flavonoids, proanthocyanidin, and accompanying phenolic constituents from Feijoa sellowiana
Hiroe Aoyama, H. Sakagami, T. Hatano
2018Bioscience, biotechnology and biochemistry49 citations Open access
Semantic Scholar
Comprehensive study on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamides.
C. Yamali, H. Sakagami, Y. Uesawa, K. Kurosaki +8 more
2021European journal of medicinal chemistry43 citations Open access
Semantic Scholar
Microwave-assisted synthesis and bioevaluation of new sulfonamides
H. Gul, C. Yamali, Fatma Yeşilyurt, H. Sakagami +4 more
2017Journal of Enzyme Inhibition and Medicinal Chemistry43 citations Open access
Semantic Scholar
Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors.
C. Yamali, H. Gul, Abdulilah Ece, Silvia Bua +4 more
2019Bioorganic chemistry (Print)38 citations
Semantic Scholar
Recent Progress of Basic Studies of Natural Products and Their Dental Application
H. Sakagami, Taihei Watanabe, T. Hoshino, N. Suda +10 more
2018Medicines28 citations Open access
Semantic Scholar
A New Method for Testing Filtration Efficiency of Mask Materials Under Sneeze-like Pressure.
Li Xiao, H. Sakagami, N. Miwa
2020In Vivo25 citations Open access
Semantic Scholar
Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones
S. Bilginer, H. Gul, F. S. Erdal, H. Sakagami +3 more
2019Journal of Enzyme Inhibition and Medicinal Chemistry25 citations Open access
Semantic Scholar
Investigation of carbonic anhydrase inhibitory effects and cytotoxicities of pyrazole-based hybrids carrying hydrazone and zinc-binding benzenesulfonamide pharmacophores.
C. Yamali, H. Sakagami, Keitaro Satoh, K. Bandow +5 more
2022Bioorganic chemistry (Print)23 citations
Semantic Scholar
Cytotoxicity, apoptosis, and QSAR studies of phenothiazine derived methoxylated chalcones as anticancer drug candidates
H. Gul, C. Yamali, Gulsen Gunesacar, H. Sakagami +3 more
2018Medicinal Chemistry Research23 citations
Semantic Scholar
Metabolomic profiling of tumor-infiltrating macrophages during tumor growth
Naoki Umemura, M. Sugimoto, Yusuke Kitoh, M. Saio +1 more
2020Cancer Immunology and Immunotherapy21 citations Open access
Semantic Scholar
Adhesion and Proliferation of Osteoblastic Cells on Hydroxyapatite-dispersed Ti-based Composite Plate
Masahiko Kobayashi, Shoichi Nihonmatsu, Takahiro Okawara, Hiroyuki Onuki +4 more
2019In Vivo21 citations Open access
Semantic Scholar
Synthesis and structure elucidation of 1-(2,5/3,5-difluorophenyl)-3-(2,3/2,4/2,5/3,4-dimethoxyphenyl)-2-propen-1-ones as anticancer agents
C. Yamali, Dilan Ozgun, Halise Inci Gul, H. Sakagami +2 more
2017Medicinal Chemistry Research21 citations Open access
Semantic Scholar
In Vitro Assessment of Antitumor Potential and Combination Effect of Classical and Molecular-targeted Anticancer Drugs
Y. Iijima, K. Bandow, Motohiko Sano, S. Hino +3 more
2019Anticancer Research20 citations Open access
Semantic Scholar
Development of Newly Synthesized Chromone Derivatives with High Tumor Specificity against Human Oral Squamous Cell Carcinoma
Y. Sugita, Koichi Takao, Y. Uesawa, Junko Nagai +3 more
2020Medicines19 citations Open access
Semantic Scholar
Protection of Differentiating Neuronal Cells from Amyloid β Peptide-induced Injury by Alkaline Extract of Leaves of Sasa senanensis Rehder.
H. Sakagami, Mayumi Tsuji, M. Tomomura, Yoshiko Masuda +17 more
2018In Vivo18 citations Open access
Semantic Scholar
Quantitative Structure-Cytotoxicity Relationship of Aurones.
Y. Uesawa, H. Sakagami, Naruhiko Ikezoe, Koichi Takao +2 more
2017Anticancer Research18 citations Open access
Semantic Scholar
Quantitative Structure-Cytotoxicity Relationship of Chalcones.
H. Sakagami, Yoshiko Masuda, M. Tomomura, S. Yokose +9 more
2017Anticancer Research18 citations Open access
Semantic Scholar
Inhibition of Neurotoxicity/Anticancer Activity of Bortezomib by Caffeic Acid and Chlorogenic Acid
Reona Matsuda, H. Sakagami, S. Amano, Y. Iijima +5 more
2022Anticancer Research17 citations
Semantic Scholar
Synthesis and biological evaluation of new pyrazolebenzene-sulphonamides as potential anticancer agents and hCA I and II inhibitors
M. Tuğrak, H. İ. Gül, H. Sakagami, Ruya Kaya +1 more
2021Turkish journal of chemistry17 citations Open access
Semantic Scholar
Exploring of tumor-associated carbonic anhydrase isoenzyme IX and XII inhibitory effects and cytotoxicities of the novel N-aryl-1-(4-sulfamoylphenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamides.
C. Yamali, Halise Inci Gul, Gulsen Ozli, A. Angeli +5 more
2021Bioorganic chemistry (Print)17 citations
Semantic Scholar
Search of Neuroprotective Polyphenols Using the “Overlay” Isolation Method
H. Sakagami, Haixia Shi, K. Bandow, M. Tomomura +4 more
2018Molecules17 citations Open access
Semantic Scholar
Quantitative Structure–Cytotoxicity Relationship of Pyrano[4,3-b]chromones
Junko Nagai, Haixia Shi, Y. Kubota, K. Bandow +7 more
2018Anticancer Research16 citations
Semantic Scholar
Synthesis, cytotoxic, and carbonic anhydrase inhibitory effects of new 2‐(3‐(4‐methoxyphenyl)‐5‐(aryl)‐4,5‐dihydro‐1H‐pyrazol‐1‐yl)benzo[d]thiazole derivatives
M. Tuğrak, H. Gul, H. Sakagami, I. Gulcin
202015 citations
Semantic Scholar
Synthesis and Cytotoxicities of New Azafluorenones with Apoptotic Mechanism of Action and Cell Cycle Analysis.
H. Gul, M. Tuğrak, M. Gul, H. Sakagami +2 more
2019Anti-Cancer Agents in Medicinal Chemistry15 citations
Semantic Scholar
Quantitative Structure–Cytotoxicity Relationship of 2-Styrylchromones
Y. Uesawa, Junko Nagai, Haixia Shi, H. Sakagami +6 more
2019Anticancer Research15 citations Open access
Semantic Scholar
Dental Application of Natural Products
H. Sakagami, M. Tomomura
2018Medicines15 citations Open access
Semantic Scholar
In Vitro Anti-tumor Activity of Azulene Amide Derivatives.
Toshiki Wada, R. Maruyama, Y. Irie, M. Hashimoto +5 more
2018In Vivo15 citations Open access
Semantic Scholar
New halogenated chalcones with cytotoxic and carbonic anhydrase inhibitory properties: 6‐(3‐Halogenated phenyl‐2‐propen‐1‐oyl)‐2(3H)‐benzoxazolones
S. Bilginer, H. Gul, F. S. Erdal, H. Sakagami +1 more
2020Archiv der Pharmazie14 citations
Semantic Scholar
Protection of Bortezomib-induced Neurotoxicity by Antioxidants
Y. Iijima, K. Bandow, S. Amano, Motohiko Sano +4 more
2020Anticancer Research14 citations Open access
Semantic Scholar
Photodynamic Therapy with Pyoktanin Blue and Diode Laser for Elimination of Enterococcus faecalis
Yoshiko Masuda, H. Sakagami, M. Horiike, H. Kadokura +4 more
2018In Vivo14 citations Open access
Semantic Scholar
Feiyanning Formula Induces Apoptosis of Lung Adenocarcinoma Cells by Activating the Mitochondrial Pathway
Limin Zhu, Hai-Xia Shi, M. Sugimoto, K. Bandow +7 more
2021Frontiers in Oncology13 citations Open access
Semantic Scholar
Kampo Therapies and the Use of Herbal Medicines in the Dentistry in Japan
Shuji Watanabe, T. Toyama, Takenori Sato, Mitsuo Suzuki +3 more
2019Medicines13 citations Open access
Semantic Scholar
QSAR Prediction Model to Search for Compounds with Selective Cytotoxicity Against Oral Cell Cancer
Junko Nagai, M. Imamura, H. Sakagami, Y. Uesawa
2019Medicines13 citations Open access
Semantic Scholar
Further Quantitative Structure–Cytotoxicity Relationship Analysis of 3-Styrylchromones
Koichi Takao, K. Hoshi, H. Sakagami, Haixia Shi +6 more
2019Anticancer Research13 citations Open access
Semantic Scholar
Lignosulfonate Rapidly Inactivates Human Immunodeficiency and Herpes Simplex Viruses
K. Fukuchi, Takuro Koshikawa, Daisuke Asai, M. Inomata +5 more
2021Medicines12 citations Open access
Semantic Scholar
Aestivalosides A-L, twelve pregnane glycosides from the seeds of Adonis aestivalis.
Minpei Kuroda, S. Kubo, Daichi Masatani, Y. Matsuo +2 more
2018Phytochemistry12 citations
Semantic Scholar
Quantitative Structure–Cytotoxicity Relationship of 3-(N-Cyclicamino)chromone Derivatives
Haixia Shi, Junko Nagai, Tsukasa Sakatsume, K. Bandow +7 more
2018Anticancer Research12 citations Open access
Semantic Scholar
A Dual Anti-Inflammatory and Anti-Proliferative 3-Styrylchromone Derivative Synergistically Enhances the Anti-Cancer Effects of DNA-Damaging Agents on Colon Cancer Cells by Targeting HMGB1-RAGE-ERK1/2 Signaling
S. Tanuma, T. Oyama, Miwa Okazawa, Hiroaki Yamazaki +5 more
2022International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Multi-Omics Analysis of Anti-Inflammatory Action of Alkaline Extract of the Leaves of Sasa sp.
H. Sakagami, S. Nakatani, A. Enomoto, S. Ota +5 more
2021Journal of Clinical Medicine11 citations Open access
Semantic Scholar
Quantitative Structure–Cytotoxicity Relationship of Furo[2,3-b]chromones
Y. Uesawa, H. Sakagami, Haixia Shi, M. Hirose +2 more
2018Anticancer Research11 citations Open access
Semantic Scholar
Design, Synthesis and Tumour-Selective Toxicity of Novel 1-[3-{3,5-Bis(benzylidene)-4-oxo-1-piperidino}-3-oxopropyl]-4-piperidone Oximes and Related Quaternary Ammonium Salts
P. K. Roayapalley, J. Dimmock, Lisett Contreras, Karol S. Balderrama +5 more
2021Molecules10 citations Open access
Semantic Scholar
EBV LMP1 in Gingival Epithelium Potentially Contributes to Human Chronic Periodontitis via Inducible IL8 Production
Norihisa Watanabe, Keiko Nodomi, Ryo Koike, A. Kato +8 more
2019In Vivo10 citations Open access
Semantic Scholar
Changes in Metabolic Profiles of Human Oral Cells by Benzylidene Ascorbates and Eugenol
H. Sakagami, M. Sugimoto, Yumiko Kanda, Y. Murakami +3 more
2018Medicines10 citations Open access
Semantic Scholar
Two new C-glycosidic ellagitannins and accompanying tannins from Lawsonia inermis leaves and their cytotoxic effects.
M. A. Orabi, H. Sakagami, Naoki Umemura, H. Alyami +1 more
2021Fitoterapia9 citations
Semantic Scholar

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Koichi Takao — researcher profile on SciRah

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Y. Sugita — researcher profile on SciRah

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C. Yamali — researcher profile on SciRah

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I. Gulcin — researcher profile on SciRah

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M. Tomomura — researcher profile on SciRah

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Junko Nagai — researcher profile on SciRah

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M. Tuğrak — researcher profile on SciRah

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A. Tomomura — researcher profile on SciRah