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Ding-I Yang · SciRah

Researcher profile · Semantic Scholar

Ding-I Yang

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Ding-I Yang — researcher profile on SciRah

h-index: 32
Works: 62
Citations: 2,523

Most-cited papers

Roles of Oxidative Stress, Apoptosis, PGC-1α and Mitochondrial Biogenesis in Cerebral Ischemia
Shang-Der Chen, Ding-I Yang, Tsu-Kung Lin, Fu-Zen Shaw +2 more
2011International Journal of Molecular Sciences352 citations Open access
Semantic Scholar
More Insight into BDNF against Neurodegeneration: Anti-Apoptosis, Anti-Oxidation, and Suppression of Autophagy
Shang-Der Chen, Chia-Lin Wu, Wei‐Chao Hwang, Ding-I Yang
2017International Journal of Molecular Sciences225 citations Open access
Semantic Scholar
Protective effects of S-nitrosoglutathione against amyloid beta-peptide neurotoxicity.
Tzyh-Chwen Ju, Shang-Der Chen, Chia-Chin Liu, Ding-I Yang
2005Free Radical Biology & Medicine106 citations
Semantic Scholar
Induction of sestrin2 as an endogenous protective mechanism against amyloid beta-peptide neurotoxicity in primary cortical culture.
Yueh-Sheng Chen, Shang-Der Chen, Chia-Lin Wu, Shiang-Suo Huang +1 more
2014Experimental Neurology73 citations
Semantic Scholar
Reduction and Restoration of Mitochondrial DNA Content After Focal Cerebral Ischemia/Reperfusion
Hong Chen, Chaur-Jong Hu, Yong Y. He, Ding-I Yang +2 more
2001Stroke71 citations Open access
Semantic Scholar
Protective effects of peroxisome proliferator‐activated receptors γ coactivator‐1α against neuronal cell death in the hippocampal CA1 subfield after transient global ischemia
Shang-Der Chen, Tsu-Kung Lin, Ding-I Yang, Su-Ying Lee +3 more
2009Journal of Neuroscience Research70 citations
Semantic Scholar
A selective inhibitor of the NLRP3 inflammasome as a potential therapeutic approach for neuroprotection in a transgenic mouse model of Huntington’s disease
Kai-Po Chen, Kuo-Feng Hua, Fu-Ting Tsai, Tingting Lin +4 more
2022Journal of Neuroinflammation67 citations Open access
Semantic Scholar
Promoter Region Methylation and Reduced Expression of Thrombospondin-1 after Oxygen—Glucose Deprivation in Murine Cerebral Endothelial Cells
Chaur-Jong Hu, Shang-Der Chen, Ding-I Yang, Teng-Nan Lin +3 more
2006Journal of Cerebral Blood Flow and Metabolism66 citations Open access
Semantic Scholar
Hyperglycemia Increases the Production of Amyloid Beta‐Peptide Leading to Decreased Endothelial Tight Junction
A-Ching Chao, Tai-Chi Lee, S. Juo, Ding-I Yang
2016CNS Neuroscience & Therapeutics63 citations Open access
Semantic Scholar
Anti-oxidative, anti-apoptotic, and pro-angiogenic effects mediate functional improvement by sonic hedgehog against focal cerebral ischemia in rats.
Shiang-Suo Huang, Henrich Cheng, Ching-Min Tang, Mao-Wei Nien +7 more
2013Experimental Neurology60 citations
Semantic Scholar
Nuclear Factor-kappaB-Dependent Sestrin2 Induction Mediates the Antioxidant Effects of BDNF Against Mitochondrial Inhibition in Rat Cortical Neurons
Chia-Lin Wu, Shang-Der Chen, Jiu-Haw Yin, Chi-shin Hwang +1 more
2016Molecular Neurobiology59 citations
Semantic Scholar
Anti-apoptotic and anti-oxidative mechanisms of minocycline against sphingomyelinase/ceramide neurotoxicity: implication in Alzheimer's disease and cerebral ischemia
Shang-Der Chen, Jiu-Haw Yin, Chi-shin Hwang, Ching-Min Tang +1 more
2012Free radical research58 citations
Semantic Scholar
Induction of hypoxia inducible factor‐1 attenuates metabolic insults induced by 3‐nitropropionic acid in rat C6 glioma cells
Ya‐Ting Yang, Tzyh-Chwen Ju, Ding-I Yang
2005Journal of Neurochemistry57 citations
Semantic Scholar
iNOS expression inhibits hypoxia-inducible factor-1 activity.
Jiu-Haw Yin, Ding-I Yang, Grace Ku, Chung Y. Hsu
2000Biochemical and Biophysical Research Communications - BBRC57 citations
Semantic Scholar
Emerging Roles of Sonic Hedgehog in Adult Neurological Diseases: Neurogenesis and Beyond
Shang-Der Chen, Jenq-Lin Yang, Wei‐Chao Hwang, Ding-I Yang
2018International Journal of Molecular Sciences56 citations Open access
Semantic Scholar
Activation of calcium/calmodulin‐dependent protein kinase IV and peroxisome proliferator‐activated receptor γ coactivator‐1α signaling pathway protects against neuronal injury and promotes mitochondrial biogenesis in the hippocampal CA1 subfield after transient global ischemia
Shang-Der Chen, Tsu-Kung Lin, Jui-Wei Lin, Ding-I Yang +4 more
2010Journal of Neuroscience Research54 citations
Semantic Scholar
Sonic hedgehog mediates BDNF-induced neuroprotection against mitochondrial inhibitor 3-nitropropionic acid.
Chia-Lin Wu, Shang-Der Chen, Chi-shin Hwang, Ding-I Yang
2009Biochemical and Biophysical Research Communications - BBRC51 citations
Semantic Scholar
Emerging Roles of Sestrins in Neurodegenerative Diseases: Counteracting Oxidative Stress and Beyond
Shang-Der Chen, Jenq-Lin Yang, Tsu-Kung Lin, Ding-I Yang
2019Journal of Clinical Medicine49 citations Open access
Semantic Scholar
Effects of rosiglitazone on global ischemia-induced hippocampal injury and expression of mitochondrial uncoupling protein 2.
Shang-Der Chen, Hsin-Yi Wu, Ding-I Yang, Su-Ying Lee +4 more
2006Biochemical and Biophysical Research Communications - BBRC46 citations
Semantic Scholar
Roles of PTEN-induced putative kinase 1 and dynamin-related protein 1 in transient global ischemia-induced hippocampal neuronal injury.
Shang-Der Chen, Tsu-Kung Lin, Ding-I Yang, Su-Ying Lee +3 more
2015Biochemical and Biophysical Research Communications - BBRC44 citations
Semantic Scholar
Neutral sphingomyelinase activation in endothelial and glial cell death induced by amyloid beta-peptide.
Ding-I Yang, C. Yeh, Sha-Wei Chen, Jan Xu +1 more
2004Neurobiology of Disease44 citations Open access
Semantic Scholar
NAD attenuates oxidative DNA damages induced by amyloid beta-peptide in primary rat cortical neurons
M.-F. Wu, Jiu-Haw Yin, Chi-shin Hwang, Ching-Min Tang +1 more
2014Free radical research43 citations
Semantic Scholar
Erythropoietin and sonic hedgehog mediate the neuroprotective effects of brain-derived neurotrophic factor against mitochondrial inhibition.
Chia-Lin Wu, Shang-Der Chen, Jiu-Haw Yin, Chi-shin Hwang +1 more
2010Neurobiology of Disease43 citations Open access
Semantic Scholar
Roles of p62 in BDNF‐dependent autophagy suppression and neuroprotection against mitochondrial dysfunction in rat cortical neurons
Chia-Lin Wu, Chien-Hui Chen, Chi-shin Hwang, Shang-Der Chen +2 more
2017Journal of Neurochemistry39 citations
Semantic Scholar
Roles of Sestrin2 and Ribosomal Protein S6 in Transient Global Ischemia-Induced Hippocampal Neuronal Injury
Yao-Chung Chuang, Jenq-Lin Yang, Ding-I Yang, Tsu-Kung Lin +2 more
2015International Journal of Molecular Sciences38 citations Open access
Semantic Scholar
Neuroprotective mechanisms of brain‐derived neurotrophic factor against 3‐nitropropionic acid toxicity: therapeutic implications for Huntington's disease
Chia-Lin Wu, Chi-shin Hwang, Shang-Der Chen, Jiu-Haw Yin +1 more
2010Annals of the New York Academy of Sciences37 citations
Semantic Scholar
Protective effects of brain-derived neurotrophic factor against neurotoxicity of 3-nitropropionic acid in rat cortical neurons.
Chia-Lin Wu, Chi-shin Hwang, Ding-I Yang
2009Neurotoxicology37 citations
Semantic Scholar
Carbamoylating chemoresistance induced by cobalt pretreatment in C6 glioma cells: putative roles of hypoxia‐inducible factor‐1
Ding-I Yang, Shang-Der Chen, Ya‐Ting Yang, Tzyh-Chwen Ju +2 more
2004British Journal of Pharmacology37 citations Open access
Semantic Scholar
Protective effects of S-nitrosoglutathione against neurotoxicity of 3-nitropropionic acid in rat.
Tzyh-Chwen Ju, Ya‐Ting Yang, Ding-I Yang
2004Neuroscience Letters36 citations
Semantic Scholar
c-Jun-dependent sulfiredoxin induction mediates BDNF protection against mitochondrial inhibition in rat cortical neurons.
Chia-Lin Wu, Jiu-Haw Yin, Chi-shin Hwang, Shang-Der Chen +2 more
2012Neurobiology of Disease33 citations Open access
Semantic Scholar
Peroxisome proliferator-activated receptor-gamma dependent pathway reduces the phosphorylation of dynamin-related protein 1 and ameliorates hippocampal injury induced by global ischemia in rats
Yao-Chung Chuang, Tsu-Kung Lin, Ding-I Yang, Jenq-Lin Yang +2 more
2016Journal of Biomedical Sciences32 citations Open access
Semantic Scholar
NO‐Mediated Chemoresistance in C6 Glioma Cells
Ding-I Yang, Jiu-Haw Yin, Snigdha Mishra, R. Mishra +1 more
2002Annals of the New York Academy of Sciences32 citations
Semantic Scholar
Roles of Id1/HIF-1 and CDK5/HIF-1 in cell cycle reentry induced by amyloid-beta peptide in post-mitotic cortical neuron.
A-Ching Chao, Chien-Hui Chen, Ming-Hsuan Wu, Bo-Yu Hou +1 more
2019Biochimica et biophysica acta. Molecular cell research24 citations Open access
Semantic Scholar
Renin inhibitor aliskiren exerts neuroprotection against amyloid beta-peptide toxicity in rat cortical neurons.
Shang-Der Chen, Chia-Lin Wu, Tsu-Kung Lin, Yao-Chung Chuang +1 more
2012Neurochemistry International24 citations
Semantic Scholar
Combination Therapy for Ischemic Stroke
Shang-Der Chen, J. Lee, Ding-I Yang, A. Nassief +1 more
2002American Journal of Cardiovascular Drugs24 citations
Semantic Scholar
Structural and functional correlates of a mutation in the malignant hyperthermia‐susceptible pig ryanodine receptor
J. Mickelson, C. Knudson, Catharine F. Kennedy, Ding-I Yang +4 more
1992FEBS Letters24 citations
Semantic Scholar
Oncostatin M-dependent Mcl-1 induction mediated by JAK1/2-STAT1/3 and CREB contributes to bioenergetic improvements and protective effects against mitochondrial dysfunction in cortical neurons.
Shih-Hsin Chang, Chi-shin Hwang, Jiu-Haw Yin, Shang-Der Chen +1 more
2015Biochimica et Biophysica Acta23 citations Open access
Semantic Scholar
Pravastatin Attenuates Ceramide‐Induced Cytotoxicity in Mouse Cerebral Endothelial Cells with HIF‐1 Activation and VEGF Upregulation
Shang-Der Chen, Chaur-Jong Hu, Ding-I Yang, A. Nassief +4 more
2005Annals of the New York Academy of Sciences23 citations
Semantic Scholar
Id1 and Sonic Hedgehog Mediate Cell Cycle Reentry and Apoptosis Induced by Amyloid Beta-Peptide in Post-mitotic Cortical Neurons
A-Ching Chao, Chien-Hui Chen, Shih-Hsin Chang, Chao-Tzu Huang +2 more
2018Molecular Neurobiology22 citations
Semantic Scholar
Statins Prevent β-Amyloid Inhibition of Sympathetic α7-nAChR-Mediated Nitrergic Neurogenic Dilation in Porcine Basilar Arteries
Minliang Si, C. Long, Ding-I Yang, Mei-Fang Chen +1 more
200522 citations Open access
Semantic Scholar
The duration of sustained convulsive seizures determines the pattern of hippocampal neurogenesis and the development of spontaneous epilepsy in rats.
Yu-Wen Hung, Ding-I Yang, Pei-Yu Huang, Tzong-Shyuan Lee +4 more
2012Epilepsy Research21 citations
Semantic Scholar
Neuroprotective mechanisms of minocycline against sphingomyelinase/ceramide toxicity: Roles of Bcl-2 and thioredoxin.
Ching-Min Tang, Chi-shin Hwang, Shang-Der Chen, Ding-I Yang
2011Free Radical Biology & Medicine21 citations
Semantic Scholar
Emerging Roles of Inhibitor of Differentiation-1 in Alzheimer’s Disease: Cell Cycle Reentry and Beyond
Shang-Der Chen, Jenq-Lin Yang, Yi-Chun Lin, A-Ching Chao +1 more
2020Cells20 citations Open access
Semantic Scholar
Inhibitor of Differentiation-1 and Hypoxia-Inducible Factor-1 Mediate Sonic Hedgehog Induction by Amyloid Beta-Peptide in Rat Cortical Neurons
Y. Hung, Shih-Hsin Chang, Chao-Tzu Huang, Jiu-Haw Yin +3 more
2014Molecular Neurobiology20 citations
Semantic Scholar
Nitric oxide and BCNU chemoresistance in C6 glioma cells: role of S-nitrosoglutathione.
Ding-I Yang, Jiu-Haw Yin, Tzyh-Chwen Ju, Long-Shiuh Chen +1 more
2004Free Radical Biology & Medicine19 citations
Semantic Scholar
Ginsenoside compound K reduces the progression of Huntington's disease via the inhibition of oxidative stress and overactivation of the ATM/AMPK pathway
Kuo-Feng Hua, A-Ching Chao, Ting-Yu Lin, Wan-Tze Chen +6 more
2021Journal of Ginseng Research17 citations Open access
Semantic Scholar
Statins prevent beta-amyloid inhibition of sympathetic alpha7-nAChR-mediated nitrergic neurogenic dilation in porcine basilar arteries.
Minliang Si, C. Long, Ding-I Yang, Mei-Fang Chen +1 more
2005Journal of Cerebral Blood Flow and Metabolism17 citations
Semantic Scholar
Protective effects of lipopolysaccharide preconditioning against nitric oxide neurotoxicity
Chia-Yen Huang, Hui-I Yang, Shang-Der Chen, Fu-Zen Shaw +1 more
2008Journal of Neuroscience Research16 citations
Semantic Scholar
The p53/NF-kappaB-dependent induction of sestrin2 by amyloid-beta peptides exerts antioxidative actions in neurons.
Yi-Heng Hsieh, A-Ching Chao, Yi-Chun Lin, Shang-Der Chen +1 more
2021Free Radical Biology & Medicine14 citations
Semantic Scholar
Potential Roles of Sestrin2 in Alzheimer’s Disease: Antioxidation, Autophagy Promotion, and Beyond
Shang-Der Chen, Jenq-Lin Yang, Yi-Heng Hsieh, Tsu-Kung Lin +3 more
2021Biomedicines12 citations Open access
Semantic Scholar

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Jiu-Haw Yin×12
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Chi-shin Hwang×12
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Yao-Chung Chuang×8

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A-Ching Chao×7

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Jenq-Lin Yang×6

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