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G. Kirby · SciRah

Researcher profile · Semantic Scholar

G. Kirby

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G. Kirby — researcher profile on SciRah

h-index: 22
Works: 59
Citations: 1,326

Most-cited papers

Human GSTA1-1 reduces c-Jun N-terminal kinase signalling and apoptosis in Caco-2 cells.
Laura Romero, K. Andrews, L. Ng, K. O’Rourke +2 more
2006Biochemical Journal85 citations Open access
Semantic Scholar
Dexamethasone-Mediated Up-Regulation of Human CYP2A6 Involves the Glucocorticoid Receptor and Increased Binding of Hepatic Nuclear Factor 4α to the Proximal Promoter
Tania Onica, Kathleen D. Nichols, M. Larin, L. Ng +6 more
2007Molecular Pharmacology81 citations
Semantic Scholar
The day/night proteome in the murine heart.
Peter S. Podobed, W. G. Pyle, S. Ackloo, Faisal J. Alibhai +8 more
2014American Journal of Physiology. Regulatory Integrative and Comparative Physiology79 citations Open access
Semantic Scholar
The Essential Oils and Eucalyptol From Artemisia vulgaris L. Prevent Acetaminophen-Induced Liver Injury by Activating Nrf2–Keap1 and Enhancing APAP Clearance Through Non-Toxic Metabolic Pathway
Zhihui Jiang, Xiao Guo, Kun-Peng Zhang, G. Sekaran +5 more
2019Frontiers in Pharmacology71 citations Open access
Semantic Scholar
Association of liver fluke (Opisthorchis viverrini) infestation with increased expression of cytochrome p450 and carcinogen metabolism in male hamster liver1,2
G. Kirby, P. Pelkonen, V. Vatanasapt, A. Camus +2 more
1994Molecular Carcinogenesis70 citations
Semantic Scholar
Overexpression of Cytochrome P-450 Isoforms Involved in Aflatoxin B1 Bioactivation in Human Liver with Cirrhosis and Hepatitis
G. Kirby, G. Batist, L. Alpert, E. Lamoureux +2 more
1996Toxicologic pathology (Print)68 citations
Semantic Scholar
Endoplasmic Reticulum Stress Due to Altered Cellular Redox Status Positively Regulates Murine Hepatic CYP2A5 Expression
W. Gilmore, G. Kirby
2004Journal of Pharmacology and Experimental Therapeutics63 citations
Semantic Scholar
Chronomics of Pressure Overload–Induced Cardiac Hypertrophy in Mice Reveals Altered Day/Night Gene Expression and Biomarkers of Heart Disease
Elena V. Tsimakouridze, M. Straume, Peter S. Podobed, Heather Chin +10 more
2012Chronobiology International51 citations
Semantic Scholar
Effects of lipopolysaccharide-stimulated inflammation and pyrazole-mediated hepatocellular injury on mouse hepatic Cyp2a5 expression.
W. Gilmore, G. Hartmann, M. Piquette-Miller, J. Marriott +1 more
2003Toxicology41 citations
Semantic Scholar
Identification of Host Defense-Related Proteins Using Label-Free Quantitative Proteomic Analysis of Milk Whey from Cows with Staphylococcus aureus Subclinical Mastitis
S. Abdelmegid, J. Murugaiyan, M. Abo-Ismail, J. Caswell +2 more
2017International Journal of Molecular Sciences38 citations Open access
Semantic Scholar
Proteomic analysis of plasma from Holstein cows testing positive for Mycobacterium avium subsp. paratuberculosis (MAP).
Q. You, C. Verschoor, S. Pant, J. Macri +2 more
2012Veterinary Immunology and Immunopathology35 citations
Semantic Scholar
Cistanche tubulosa ethanol extract mediates rat sex hormone levels by induction of testicular steroidgenic enzymes
Tian Wang, Chen Chen, May Yang, Bai-Wan Deng +2 more
2016Pharmaceutical Biology33 citations Open access
Semantic Scholar
CYP2A5 induction and hepatocellular stress: an adaptive response to perturbations of heme homeostasis.
G. Kirby, Kathleen D. Nichols, Monica Antenos
2011Current drug metabolism31 citations
Semantic Scholar
Microarray analysis of hepatic gene expression in pyrazole-mediated hepatotoxicity: identification of potential stimuli of Cyp2a5 induction.
Kathleen D. Nichols, G. Kirby
2008Biochemical Pharmacology30 citations
Semantic Scholar
Dexrazoxane does not protect against doxorubicin-induced damage in young rats.
S. Héon, M. Bernier, N. Servant, Stevan Dostanic +4 more
2003American Journal of Physiology. Heart and Circulatory Physiology28 citations
Semantic Scholar
Allele‐specific PCR analysis of p53 codon 249 AGT transversion in liver tissues from patients with viral hepatitis
G. Kirby, G. Batist, N. Fotouhi‐Ardakani, H. Nakazawa +4 more
1996International Journal of Cancer28 citations Open access
Semantic Scholar
Echinacoside Increases Sperm Quantity in Rats by Targeting the Hypothalamic Androgen Receptor
Zhihui Jiang, Bo Zhou, Xinping Li, G. Kirby +1 more
2018Scientific Reports27 citations Open access
Semantic Scholar
Assessment of platelet function in healthy cats in response to commonly prescribed antiplatelet drugs using three point-of-care platelet function tests
Kimberly K. Ho, A. Abrams-Ogg, R. D. Wood, M. O'Sullivan +2 more
2017Journal of feline medicine and surgery26 citations Open access
Semantic Scholar
Cytochrome P450 2A5 and bilirubin: mechanisms of gene regulation and cytoprotection.
Sangsoo Kim, Monica Antenos, E. Squires, G. Kirby
2013Toxicology and Applied Pharmacology25 citations Open access
Semantic Scholar
Down-regulation of alpha class glutathione S-transferase by interleukin-1beta in human intestinal epithelial cells (Caco-2) in culture.
Laura Romero, M. A. Higgins, James Gilmore, Kim Boudreau +3 more
2002Drug Metabolism And Disposition24 citations
Semantic Scholar
Assessment of platelet function in healthy sedated cats using three whole blood platelet function tests
Kimberly K. Ho, A. Abrams-Ogg, R. D. Wood, M. L. O'Sullivan +2 more
2015Journal of Veterinary Diagnostic Investigation23 citations Open access
Semantic Scholar
The effect of menadione on glutathione S-transferase A1 (GSTA1): c-Jun N-terminal kinase (JNK) complex dissociation in human colonic adenocarcinoma Caco-2 cells.
Humaira Adnan, Monica Antenos, G. Kirby
2012Toxicology Letters23 citations
Semantic Scholar
Low Levels of GSTA1 Expression Are Required for Caco-2 Cell Proliferation
Humaira Adnan, H. Quach, Kimberley MacIntosh, Monica Antenos +1 more
2012PLoS ONE22 citations Open access
Semantic Scholar
Expression of cytochrome P450 2A5 in a glucose-6-phosphate dehydrogenase-deficient mouse model of oxidative stress.
Kathleen D. Nichols, G. Kirby
2008Biochemical Pharmacology21 citations
Semantic Scholar
Ultrasonographic and laboratory screening in clinically normal mature golden retriever dogs.
J. Webb, G. Kirby, S. Nykamp, M. Gauthier
2012The Canadian veterinary journal = La revue veterinaire canadienne20 citations
Semantic Scholar
Chemical Inducers of Rodent Glutathione S-Transferases Down-Regulate Human GSTA1 Transcription through a Mechanism Involving Variant Hepatic Nuclear Factor 1-C
Laura Romero, L. Ng, G. Kirby
2006Molecular Pharmacology20 citations
Semantic Scholar
Loss of glutathione S-transferases in pollution-associated liver neoplasms in white suckers (Catostomus commersoni) from Lake Ontario.
M. Stalker, G. Kirby, T. Koçal, I. R. Smith +1 more
1991Carcinogenesis20 citations
Semantic Scholar
Concentration of lipocalin region of collagen XXVII alpha 1 in the serum of dogs with hemangiosarcoma.
G. Kirby, A. Mackay, A. Grant, P. Woods +5 more
2011Journal of Veterinary Internal Medicine19 citations Open access
Semantic Scholar
Identification of a 43-kDa protein in human liver cytosol that binds to the 3'-untranslated region of CYP2A6 mRNA.
James Gilmore, Francesca Rotondo, Anne-Marie Pelletier, J. LaMarre +2 more
2001Biochemical Pharmacology18 citations
Semantic Scholar
Detection of Mycobacterium avium Subspecies paratuberculosis (MAP) Microorganisms Using Antigenic MAP Cell Envelope Proteins
S. Karuppusamy, L. Mutharia, D. Kelton, B. Plattner +3 more
2021Frontiers in Veterinary Science15 citations Open access
Semantic Scholar
Metabolism of nitrosamines and aflatoxin B1 by hamster liver CYP2A enzymes.
P. Pelkonen, G. Kirby, C. P. Wild, H. Bartsch +1 more
1994Chemico-Biological Interactions15 citations
Semantic Scholar
Proteomic 2D-DIGE Analysis of Milk Whey from Dairy Cows with Staphylococcus aureus Mastitis Reveals Overexpression of Host Defense Proteins
S. Abdelmegid, D. Kelton, J. Caswell, G. Kirby
2020Microorganisms14 citations Open access
Semantic Scholar
Serum Lipid, Amino Acid and Acylcarnitine Profiles of Obese Cats Supplemented with Dietary Choline and Fed to Maintenance Energy Requirements
A. Verbrugghe, Alexandra Rankovic, Shafeeq Armstrong, A. Santarossa +2 more
2021Animals13 citations Open access
Semantic Scholar
Gender-Dependent Reductions in Vertebrae Length, Bone Mineral Density and Content by Doxorubicin Are Not Reduced by Dexrazoxane in Young Rats: Effect on Growth Plate and Intervertebral Discs
F. Mwale, J. Antoniou, S. Héon, N. Servant +4 more
2005Calcified Tissue International13 citations
Semantic Scholar
Repression of Human GSTA1 by Interleukin-1β Is Mediated by Variant Hepatic Nuclear Factor-1C
L. Ng, Kathleen D. Nichols, K. O’Rourke, Ann Maslen +1 more
2007Molecular Pharmacology12 citations
Semantic Scholar
Enhanced Hexachloro-1:3-butadiene Nephrotoxicity in Rats with a Preexisting Adriamycin-Induced Nephrotic Syndrome
G. Kirby, P. H. Bach
1995Toxicologic pathology (Print)12 citations Open access
Semantic Scholar
The role of glutathione S-transferases in the hepatic metabolism of benzo[a]pyrene in white suckers (Catostomus commersoni) from polluted and reference sites in the Great Lakes.
G. Kirby, J. R. Bend, I. R. Smith, M. Hayes
1990Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology12 citations
Semantic Scholar
An update on Mycobacterium avium subspecies paratuberculosis antigens and their role in the diagnosis of Johne’s disease
S. Karuppusamy, G. Kirby, L. Mutharia, B. N. Tripathi
2019World Journal of Microbiology & Biotechnology11 citations
Semantic Scholar
Human GSTA 1-1 reduces c-Jun N-terminal kinase signalling and apoptosis in Caco-2 cells
Laura Romero, K. Andrews, N. Lorraine, K. O’Rourke +2 more
200611 citations
Semantic Scholar
Loss of glutathione S-transferase (GST) mu phenotype in colorectal adenocarcinomas from patients with a GSTM1 positive genotype.
Heather J Barker, L. Alpert, C. Compton, Ann Maslen +1 more
2002Cancer Letters11 citations
Semantic Scholar
Identification of antigenic proteins from Mycobacterium avium subspecies paratuberculosis cell envelope by comparative proteomic analysis.
S. Karuppusamy, L. Mutharia, D. Kelton, N. Karrow +1 more
2018Microbiology10 citations Open access
Semantic Scholar
Influences of chronic cholangiohepatitis and cholestasis on hepatic metabolism of benzo[a]pyrene in white suckers (Catostomus commersoni) from industrially polluted areas of Lake Ontario.
G. Kirby, M. Stalker, S. Gordon, B. Quinn +2 more
1995Carcinogenesis9 citations
Semantic Scholar
Dose-response relationship between dietary choline and serum lipid profile, energy expenditure and respiratory quotient in overweight adult cats fed at maintenance energy requirements.
Alexandra Rankovic, Hannah Godfrey, Caitlin E. Grant, A. Shoveller +3 more
2022Journal of Animal Science8 citations Open access
Semantic Scholar
Dietary choline, but not L-carnitine, increases circulating lipid and lipoprotein concentrations, without affecting body composition, energy expenditure or respiratory quotient in lean and obese male cats during weight maintenance
Alexandra Rankovic, Shoshana Verton-Shaw, A. Shoveller, M. Bakovic +2 more
2023Frontiers in Veterinary Science7 citations Open access
Semantic Scholar
Serum metabolomic analysis of the dose-response effect of dietary choline in overweight male cats fed at maintenance energy requirements
Alexandra Rankovic, Hannah Godfrey, Caitlin E. Grant, A. Shoveller +3 more
2023PLoS ONE6 citations Open access
Semantic Scholar
Regulation of Cytochrome P450 2a5 by Artemisia capillaris and 6,7-Dimethylesculetin in Mouse Hepatocytes
Sangsoo Kim, L. Morgan, E. Hargreaves, Xiao-Ying Zhang +4 more
2021Frontiers in Pharmacology6 citations Open access
Semantic Scholar
Circadian Proteomics and Its Unique Advantage for Discovery of Biomarkers of Heart Disease
Peter S. Podobed, G. Kirby, T. Martino
20125 citations Open access
Semantic Scholar
Effect of Extracellular Matrix on Gene Expression and mRNA Stability in Primary Rat Hepatocytes
S. Benn, A. Allan, J. E. Laithwaite, Y. Tsukamoto +3 more
19985 citations Open access
Semantic Scholar
Nrf2-mediated induction of Cyp2a5 partially protects against reductive endoplasmic reticulum stress in mouse hepatocytes.
Larry Morgan, Monica Antenos, G. Kirby
2022Toxicology4 citations Open access
Semantic Scholar
Mass spectrometry data from identification of host-defense related proteins using label-free quantitative proteomic analysis of milk whey from cows with Staphylococcus aureus subclinical mastitis
S. Abdelmegid, J. Murugaiyan, M. Abo-Ismail, J. Caswell +2 more
2019Data in Brief4 citations Open access
Semantic Scholar

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