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Wen-Chan Tsai · SciRah

Researcher profile · Semantic Scholar

Wen-Chan Tsai

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Wen-Chan Tsai — researcher profile on SciRah

h-index: 30
Works: 125
Citations: 3,596

Most-cited papers

Increased incidence of rheumatoid arthritis in multiple sclerosis
Chia-Chun Tseng, Shun-Jen Chang, Wen-Chan Tsai, Tsan-Teng Ou +4 more
2016Medicine974 citations Open access
Semantic Scholar
The impact of anti-drug antibodies on drug concentrations and clinical outcomes in rheumatoid arthritis patients treated with adalimumab, etanercept, or infliximab: Results from a multinational, real-world clinical practice, non-interventional study
R. Moots, R. Xavier, C. Mok, Mahboob Rahman +10 more
2017PLoS ONE131 citations Open access
Semantic Scholar
Significant associations of antidrug antibody levels with serum drug trough levels and therapeutic response of adalimumab and etanercept treatment in rheumatoid arthritis
Der-Yuan Chen, Yi-Ming Chen, Wen-Chan Tsai, Jui-Cheng Tseng +4 more
2014Annals of the Rheumatic Diseases114 citations
Semantic Scholar
Global DNA methylation, DNMT1, and MBD2 in patients with rheumatoid arthritis.
Ching-Ching Liu, Tzu-Jung Fang, Tsan-Teng Ou, Cheng-Chin Wu +6 more
2011Immunology Letters114 citations
Semantic Scholar
High prevalence of immunoglobulin A antibody against Epstein-Barr virus capsid antigen in adult patients with lupus with disease flare: case control studies.
Chung-Jen Chen, K. Lin, Shih-Chang Lin, Wen-Chan Tsai +4 more
2005Journal of Rheumatology77 citations
Semantic Scholar
HLA-B27-mediated activation of TNAP phosphatase promotes pathogenic syndesmophyte formation in ankylosing spondylitis.
Chin-Hsiu Liu, S. Raj, Chun-Hsiung Chen, Kuo-Hsuan Hung +11 more
2019Journal of Clinical Investigation65 citations Open access
Semantic Scholar
Programmed Death-1 Gene Polymorphisms in Patients With Systemic Lupus Erythematosus in Taiwan
Shu-Chen Wang, Yi-Jing Chen, Tsan-Teng Ou, Cheng-Chin Wu +3 more
2006Journal of Clinical Immunology63 citations
Semantic Scholar
Detecting Epstein-Barr virus DNA from peripheral blood mononuclear cells in adult patients with systemic lupus erythematosus in Taiwan
Shan-Fu Yu, Huei-Chuin Wu, Wen-Chan Tsai, J. Yen +5 more
2005Medical Microbiology and Immmunology63 citations
Semantic Scholar
Use of HLA-B*58:01 genotyping to prevent allopurinol induced severe cutaneous adverse reactions in Taiwan: national prospective cohort study
Tai-Ming Ko, Chang-Youh Tsai, Shih-Yang Chen, Kuo-Shu Chen +42 more
2015British medical journal61 citations Open access
Semantic Scholar
Antinuclear antibody is associated with a more advanced fibrosis and lower RNA levels of hepatitis C virus in patients with chronic hepatitis C
Ming-Yen Hsieh, Chia-Yen Dai, L. Lee, Jee-Fu Huang +8 more
2007Journal of Clinical Pathology60 citations
Semantic Scholar
Dual Role of Chondrocytes in Rheumatoid Arthritis: The Chicken and the Egg
Chia-Chun Tseng, Yi-Jen Chen, Wei-An Chang, Wen-Chan Tsai +5 more
2020International Journal of Molecular Sciences54 citations Open access
Semantic Scholar
Long-Term Frequent Use of Non-Steroidal Anti-Inflammatory Drugs Might Protect Patients with Ankylosing Spondylitis from Cardiovascular Diseases: A Nationwide Case-Control Study
Wen-Chan Tsai, Tsan-Teng Ou, J. Yen, Cheng-Chin Wu +1 more
2015PLoS ONE54 citations Open access
Semantic Scholar
Tumor necrosis factor‐alpha inhibitors suppress CCL2 chemokine in monocytes via epigenetic modification
Yi-Ching Lin, Yu-Chih Lin, Ming-Yii Huang, P. Kuo +7 more
2017Molecular Immunology42 citations
Semantic Scholar
Association Between Gout and Incident Type 2 Diabetes Mellitus: A Retrospective Cohort Study.
Y. Tung, Su-Shin Lee, Wen-Chan Tsai, Gau-Tyan Lin +2 more
2016American Journal of Medicine42 citations
Semantic Scholar
Demethylation within the proximal promoter region of human estrogen receptor alpha gene correlates with its enhanced expression: Implications for female bias in lupus.
Hong-Wen Liu, Hui-li Lin, J. Yen, Wen-Chan Tsai +5 more
2014Molecular Immunology41 citations
Semantic Scholar
Parvovirus B19 infection in patients with rheumatoid arthritis in Taiwan.
Yueh-Sheng Chen, P. Chou, Shuixian Li, Wen-Chan Tsai +4 more
2006Journal of Rheumatology39 citations
Semantic Scholar
Evaluation of Health Outcomes with Etanercept Treatment in Patients with Early Nonradiographic Axial Spondyloarthritis
M. Dougados, Wen-Chan Tsai, D. Saaibi, R. Bonin +4 more
2015Journal of Rheumatology37 citations Open access
Semantic Scholar
Role of Low‐Density Lipoprotein in Early Vascular Aging Associated With Systemic Lupus Erythematosus
Hua-Chen Chan, H. Chan, chan‐jung liang, Hsiang-Chun Lee +11 more
2020Arthritis & Rheumatology33 citations
Semantic Scholar
Predictors of drug survival for biologic and targeted synthetic DMARDs in rheumatoid arthritis: Analysis from the TRA Clinical Electronic Registry
Ching-Tsai Lin, Wen-Nan Huang, Wen-Chan Tsai, Jun-Peng Chen +10 more
2021PLoS ONE31 citations Open access
Semantic Scholar
IkBα Promoter Polymorphisms in Patients with Primary Sjögren’s Syndrome
Tsan-Teng Ou, Chia-Hui Lin, Yu-Chih Lin, Ruei-Nian Li +3 more
2008Journal of Clinical Immunology30 citations
Semantic Scholar
β-thalassemia major evolution from β-thalassemia minor is associated with paternal uniparental isodisomy of chromosome 11p15
Jan-Gowth Chang, Wen-Chan Tsai, I. Chong, Chao-Sung Chang +2 more
2008Haematologica28 citations Open access
Semantic Scholar
The Role of Macrophages in Connective Tissue Disease-Associated Interstitial Lung Disease: Focusing on Molecular Mechanisms and Potential Treatment Strategies
Chia-Chun Tseng, Ya-Wen Sung, Kuan-Yu Chen, Pin-Yi Wang +10 more
2023International Journal of Molecular Sciences26 citations Open access
Semantic Scholar
Alcohol-related diseases and alcohol dependence syndrome is associated with increased gout risk: A nationwide population-based cohort study.
H. Tu, Y. Tung, Wen-Chan Tsai, Gau-Tyan Lin +2 more
2017Joint, bone, spine : revue du rhumatisme25 citations
Semantic Scholar
Ligands for programmed cell death 1 gene in patients with systemic lupus erythematosus.
Shu-Chen Wang, Chia-Hui Lin, Tsan-Teng Ou, Cheng-Chin Wu +4 more
2007Journal of Rheumatology24 citations
Semantic Scholar
Study of undifferentiated spondyloarthropathy among first-degree relatives of ankylosing spondylitis probands.
C.-T. Chou, Kuan-Chia Lin, J. Wei, Wen-Chan Tsai +5 more
2005Rheumatology24 citations
Semantic Scholar
Consensus recommendations on managing the selected comorbidities including cardiovascular disease, osteoporosis, and interstitial lung disease in rheumatoid arthritis
Kuang-Hui Yu, Hsin-Hua Chen, T. Cheng, Y. Jan +11 more
2022Medicine23 citations Open access
Semantic Scholar
The immunomodulatory effects of TNF-α inhibitors on human Th17 cells via RORγt histone acetylation
Yi-Ching Lin, Yu-Chih Lin, Cheng-Chin Wu, Ming-Yii Huang +3 more
2016OncoTarget23 citations Open access
Semantic Scholar
IκBα Promoter Polymorphisms in Patients with Systemic Lupus Erythematosus
Chia-Hui Lin, Shu-Chen Wang, Tsan-Teng Ou, Ruei-Nian Li +3 more
2008Journal of Clinical Immunology20 citations
Semantic Scholar
In vitro folate deficiency induces apoptosis by a p53, Fas (Apo-1, CD95) independent, bcl-2 related mechanism in phytohaemagglutinin-stimulated human peripheral blood lymphocytes
Hui-li Lin, Chung-Jern Chen, Wen-Chan Tsai, J. Yen +1 more
2006British Journal of Nutrition20 citations Open access
Semantic Scholar
Risk of incident benign prostatic hyperplasia in patients with gout: a retrospective cohort study
Wei-Ming Li, Nelly Pasaribu, Su-Shin Lee, Wen-Chan Tsai +5 more
2018Prostate Cancer and Prostatic Diseases19 citations
Semantic Scholar
Defective Mycobacterium tuberculosis antigen presentation by monocytes from tuberculosis patients.
Y. Tung, Tsan-Teng Ou, Wen-Chan Tsai
2013The International Journal of Tuberculosis and Lung Disease19 citations
Semantic Scholar
HLA-B27 and Ankylosing Spondylitis
Wen-Chan Tsai
201219 citations Open access
Semantic Scholar
Polymorphisms of Genes for Programmed Cell Death 1 Ligands in Patients with Rheumatoid Arthritis
Shu-Chen Wang, Chia-Hui Lin, Ruei-Nian Li, Tsan-Teng Ou +4 more
2007Journal of Clinical Immunology19 citations
Semantic Scholar
Increased Incidence of Herpes Zoster and Postherpetic Neuralgia in Adult Patients following Traumatic Brain Injury: A Nationwide Population-Based Study in Taiwan
Y. Tung, H. Tu, Wen-Chan Tsai, Cheng-Sheng Chen +3 more
2015PLoS ONE18 citations Open access
Semantic Scholar
Recommendations for psoriatic arthritis management: A joint position paper of the Taiwan Rheumatology Association and the Taiwanese Association for Psoriasis and Skin Immunology.
T. Tsai, Tsu-Yi Hsieh, Ching-Chi Chi, Chung T. Chou +24 more
2020Journal of the Formosan Medical Association = Taiwan yi zhi17 citations Open access
Semantic Scholar
Differential Expression Profiles of the Transcriptome and miRNA Interactome in Synovial Fibroblasts of Rheumatoid Arthritis Revealed by Next Generation Sequencing
Chia-Chun Tseng, Ling-Yu Wu, Wen-Chan Tsai, Tsan-Teng Ou +4 more
2019Diagnostics17 citations Open access
Semantic Scholar
Methylation and gene expression of histone deacetylases 6 in systemic lupus erythematosus
Tzu-Jung Fang, Yuan-Zhao Lin, Ching-Ching Liu, Chia-Hui Lin +5 more
2016International Journal of Rheumatic Diseases17 citations
Semantic Scholar
Taiwan Rheumatology Association consensus recommendations for the management of axial spondyloarthritis
J. Wei, Chin-Hsiu Liu, Jui-Cheng Tseng, Lin-Fen Hsieh +11 more
2019International Journal of Rheumatic Diseases16 citations Open access
Semantic Scholar
Inhibitors of kB-like gene polymorphisms in rheumatoid arthritis.
Chia-Hui Lin, C. Cho, Wen-Chan Tsai, Tsan-Teng Ou +3 more
2006Immunology Letters16 citations
Semantic Scholar
Efficacy and safety of tofacitinib for the treatment of rheumatoid arthritis in patients from the Asia‐Pacific region: Post‐hoc analyses of pooled clinical study data
E. B. Lee, H. Yamanaka, Yi Liu, Wen-Chan Tsai +8 more
2019International Journal of Rheumatic Diseases15 citations Open access
Semantic Scholar
Estradiol upregulates calcineurin expression via overexpression of estrogen receptor alpha gene in systemic lupus erythematosus
Hui-li Lin, J. Yen, S. Chiou, Wen-Chan Tsai +3 more
2011Kaohsiung Journal of Medical Sciences15 citations Open access
Semantic Scholar
Rare Extra‐articular Manifestation of Rheumatoid Arthritis: Scleromalacia Perforans
Chen‐Ching Wu, J. Yen, Wen-Chan Tsai, Hong-Wen Liu +1 more
2005Kaohsiung Journal of Medical Sciences15 citations Open access
Semantic Scholar
GADD45a and GADD45b Genes in Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients
Ruei-Nian Li, Yuan-Zhao Lin, Ya-Chun Pan, Chia-Hui Lin +6 more
2019Journal of Clinical Medicine14 citations Open access
Semantic Scholar
F11R mRNA expression and promoter polymorphisms in patients with rheumatoid arthritis
Tzu-Jung Fang, Chia-Hui Lin, Yuan-Zhao Lin, Ruei-Nian Li +4 more
2016International Journal of Rheumatic Diseases13 citations
Semantic Scholar
Increased Cumulative Incidence of Dermatomyositis in Ulcerative Colitis: a Nationwide Cohort Study
Chia-Chun Tseng, Shun-Jen Chang, Wei-Ting Liao, Y. Chan +6 more
2016Scientific Reports13 citations Open access
Semantic Scholar
Next-Generation Sequencing Profiles of the Methylome and Transcriptome in Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis
Chia-Chun Tseng, Yuan-Zhao Lin, Chia-Hui Lin, Ruei-Nian Li +7 more
2019Journal of Clinical Medicine12 citations Open access
Semantic Scholar
Sex differential association of dermatomyositis with Sjögren syndrome
Chia-Chun Tseng, Shun-Jen Chang, Wen-Chan Tsai, Tsan-Teng Ou +4 more
2017Canadian Medical Association Journal12 citations Open access
Semantic Scholar
Correction: The impact of anti-drug antibodies on drug concentrations and clinical outcomes in rheumatoid arthritis patients treated with adalimumab, etanercept, or infliximab: Results from a multinational, real-world clinical practice, non-interventional study
R. Moots, R. Xavier, C. Mok, Mahboob Rahman +10 more
2017PLoS ONE12 citations Open access
Semantic Scholar
The epidemiologic transition of thalassemia and associated hemoglobinopathies in southern Taiwan
Hui-Ching Wang, Li-Ling Hsieh, Yi-Chang Liu, Hui-Hua Hsiao +3 more
2017Annals of Hematology12 citations
Semantic Scholar
Update on Biosimilars in Asia
Wen-Chan Tsai
2017Current Rheumatology Reports12 citations
Semantic Scholar

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Tsan-Teng Ou×23
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Hong-Wen Liu×13
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Chia-Chun Tseng×8

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Ruei-Nian Li×8

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Y. Tung — researcher profile on SciRah

Shun-Jen Chang×5

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Der-Yuan Chen×4

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