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K. Le Blanc · SciRah

Researcher profile · Semantic Scholar

K. Le Blanc

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K. Le Blanc — researcher profile on SciRah

h-index: 74
Works: 207
Citations: 49K

Most-cited papers

Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting
O. Wiklander, Joel Z. Nordin, Aisling J. O'Loughlin, Y. Gustafsson +14 more
2015Journal of Extracellular Vesicles1,605 citations Open access
Semantic Scholar
Multipotent mesenchymal stromal cells and the innate immune system
K. Le Blanc, D. Mougiakakos
2012Nature reviews. Immunology961 citations
Semantic Scholar
Analysis of Tissues Following Mesenchymal Stromal Cell Therapy in Humans Indicates Limited Long‐Term Engraftment and No Ectopic Tissue Formation
L. von Bahr, I. Batsis, Guido Moll, M. Hägg +5 more
2012Stem Cells548 citations
Semantic Scholar
Are Therapeutic Human Mesenchymal Stromal Cells Compatible with Human Blood?
Guido Moll, Ida Rasmusson‐Duprez, L. von Bahr, Anne-Marie Connolly-Andersen +12 more
2012Stem Cells336 citations Open access
Semantic Scholar
Mesenchymal Stromal Cell Secretion of Programmed Death‐1 Ligands Regulates T Cell Mediated Immunosuppression
L. Davies, N. Heldring, N. Kadri, K. Le Blanc
2016Stem Cells320 citations Open access
Semantic Scholar
Long-term complications, immunologic effects, and role of passage for outcome in mesenchymal stromal cell therapy.
L. von Bahr, B. Sundberg, Lena Lönnies, B. Sander +7 more
2012Biology of Blood and Marrow Transplantation318 citations Open access
Semantic Scholar
Preserved β-Cell Function in Type 1 Diabetes by Mesenchymal Stromal Cells
P. Carlsson, Erik Schwarcz, O. Korsgren, K. Le Blanc
2014Diabetes272 citations Open access
Semantic Scholar
CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs.
R. Jitschin, Martina Braun, M. Büttner, K. Dettmer-Wilde +8 more
2014Blood247 citations
Semantic Scholar
Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid‐refractory, grade III–IV acute graft‐versus‐host disease
L. M. Ball, M. E. Bernardo, H. Roelofs, M. Tol +14 more
2013British Journal of Haematology243 citations Open access
Semantic Scholar
Mesenchymal stromal cells and the innate immune response.
K. Le Blanc, L. Davies
2015Immunology Letters242 citations Open access
Semantic Scholar
Mesenchymal stromal cells: Putative microenvironmental modulators become cell therapy.
M. Krampera, K. Le Blanc
2021Cell Stem Cell211 citations Open access
Semantic Scholar
Pre‐ and Postnatal Transplantation of Fetal Mesenchymal Stem Cells in Osteogenesis Imperfecta: A Two‐Center Experience
C. Götherström, M. Westgren, S. S. Steven Shaw, E. Åström +13 more
2014Stem Cells Translational Medicine186 citations Open access
Semantic Scholar
Therapeutic Potential of Multipotent Mesenchymal Stromal Cells and Their Extracellular Vesicles
N. Heldring, I. Mäger, M. Wood, K. Le Blanc +1 more
2015Human Gene Therapy180 citations
Semantic Scholar
In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome
Oscar E. Simonson, D. Mougiakakos, N. Heldring, Giulio Bassi +24 more
2015Stem Cells Translational Medicine158 citations Open access
Semantic Scholar
Primary Mesenchymal Stem and Progenitor Cells from Bone Marrow Lack Expression of CD44 Protein*
H. Qian, K. Le Blanc, M. Sigvardsson
2012Journal of Biological Chemistry153 citations Open access
Semantic Scholar
Challenges for mesenchymal stromal cell therapies
I. Martin, J. Galipeau, C. Kessler, K. Le Blanc +1 more
2019Science Translational Medicine145 citations
Semantic Scholar
Improved survival after allogeneic hematopoietic stem cell transplantation in recent years. A single-center study.
M. Remberger, M. Ackefors, S. Berglund, O. Blennow +34 more
2011Biology of Blood and Marrow Transplantation142 citations Open access
Semantic Scholar
Targeting Suppressive Myeloid Cells Potentiates Checkpoint Inhibitors to Control Spontaneous Neuroblastoma
Yumeng Mao, N. Eissler, K. Le Blanc, J. Johnsen +2 more
2016Clinical Cancer Research131 citations
Semantic Scholar
Immunosuppressive CD14+HLA-DRlow/neg IDO+ myeloid cells in patients following allogeneic hematopoietic stem cell transplantation
D. Mougiakakos, R. Jitschin, L. von Bahr, I. Poschke +5 more
2013Leukemia123 citations Open access
Semantic Scholar
MSCs-cells with many sides.
K. Le Blanc, L. Davies
2018Cytotherapy106 citations
Semantic Scholar
Current perspectives on mesenchymal stromal cell therapy for graft versus host disease
N. Kadri, S. Amu, Ellen Iacobaeus, E. Boberg +1 more
2023Cellular & Molecular Immunology102 citations Open access
Semantic Scholar
Stromal cell-mediated glycolytic switch in CLL cells involves Notch-c-Myc signaling.
R. Jitschin, Martina Braun, Mirjeta Qorraj, Domenica Saul +3 more
2015Blood96 citations
Semantic Scholar
Alterations in the Cellular Immune Compartment of Patients Treated with Third‐Party Mesenchymal Stromal Cells Following Allogeneic Hematopoietic Stem Cell Transplantation
R. Jitschin, D. Mougiakakos, L. von Bahr, S. Völkl +5 more
2013Stem Cells79 citations Open access
Semantic Scholar
Do ABO Blood Group Antigens Hamper the Therapeutic Efficacy of Mesenchymal Stromal Cells?
Guido Moll, A. Hult, L. von Bahr, J. Alm +10 more
2014PLoS ONE77 citations Open access
Semantic Scholar
Manufacturing Mesenchymal Stromal Cells for the Treatment of Graft-versus-Host Disease: A Survey among Centers Affiliated with the European Society for Blood and Marrow Transplantation
C. Trento, M. Bernardo, A. Nagler, S. Kuçi +20 more
2018Biology of Blood and Marrow Transplantation74 citations Open access
Semantic Scholar
Targeted Intra-arterial Transplantation of Stem Cells to the Injured CNS is more Effective than Intravenous Administration: Engraftment is Dependent on Cell Type and Adhesion Molecule Expression
J. Lundberg, E. Södersten, E. Sundström, K. Le Blanc +3 more
2012Cell Transplantation65 citations Open access
Semantic Scholar
A prospective randomized toxicity study to compare reduced‐intensity and myeloablative conditioning in patients with myeloid leukaemia undergoing allogeneic haematopoietic stem cell transplantation
O. Ringdén, T. Erkers, J. Aschan, K. Garming-Legert +8 more
2013Journal of Internal Medicine61 citations Open access
Semantic Scholar
Increased incidence of chronic GvHD and CMV disease in patients with vitamin D deficiency before allogeneic stem cell transplantation
L. von Bahr, O. Blennow, J. Alm, A. Björklund +7 more
2015Bone Marrow Transplantation59 citations Open access
Semantic Scholar
Human Embryonic Stem Cell-Derived Mesenchymal Stroma Cells (hES-MSCs) Engraft In Vivo and Support Hematopoiesis without Suppressing Immune Function: Implications for Off-The Shelf ES-MSC Therapies
Ou Li, Ariane Tormin, B. Sundberg, J. Hyllner +2 more
2013PLoS ONE58 citations Open access
Semantic Scholar
Defined serum-free media for in vitro expansion of adipose-derived mesenchymal stem cells.
S. H. Al-Saqi, M. Saliem, Suvi Asikainen, H. C. Quezada +5 more
2014Cytotherapy57 citations
Semantic Scholar
Treatment of chronic GvHD with mesenchymal stromal cells induces durable responses: A phase II study
E. Boberg, L. von Bahr, G. Afram, Carina Lindström +6 more
2020Stem Cells Translational Medicine49 citations Open access
Semantic Scholar
Oral Mucosal Progenitor Cells Are Potently Immunosuppressive in a Dose-Independent Manner
L. Davies, H. Lönnies, M. Locke, B. Sundberg +4 more
2012Stem Cells and Development49 citations Open access
Semantic Scholar
ISCT MSC committee statement on the US FDA approval of allogenic bone-marrow mesenchymal stromal cells.
K. Le Blanc, F. Dazzi, Karen English, D. Farge +10 more
2025Cytotherapy48 citations
Semantic Scholar
MSC from fetal and adult lungs possess lung-specific properties compared to bone marrow-derived MSC
Sara Rolandsson Enes, A. Andersson-Sjöland, I. Skog, L. Hansson +6 more
2016Scientific Reports45 citations Open access
Semantic Scholar
The Complement System Is Essential for the Phagocytosis of Mesenchymal Stromal Cells by Monocytes
C. Gavin, S. Meinke, N. Heldring, K. Heck +5 more
2019Frontiers in Immunology44 citations Open access
Semantic Scholar
Phenotypic and functional alterations of myeloid‐derived suppressor cells during the disease course of multiple sclerosis
Ellen Iacobaeus, I. Douagi, R. Jitschin, Maritha Marcusson-Ståhl +7 more
2018Immunology and Cell Biology44 citations
Semantic Scholar
Mesenchymal Stromal Cells Disrupt mTOR‐Signaling and Aerobic Glycolysis During T‐Cell Activation
Martin Böttcher, A. Hofmann, H. Bruns, Martina Haibach +6 more
2016Stem Cells44 citations Open access
Semantic Scholar
Ten years follow up after prenatal transplantation of fetal mesenchymal stem cell in a patient with severe osteogenesis imperfecta
C. Götherström, K. Le Blanc, E. Åström, Jahan Taslimi +3 more
201343 citations Open access
Semantic Scholar
Dynamic Changes in Brain Mesenchymal Perivascular Cells Associate with Multiple Sclerosis Disease Duration, Active Inflammation, and Demyelination
Ellen Iacobaeus, R. Sugars, Anton Törnqvist Andrén, J. Alm +8 more
2017Stem Cells Translational Medicine42 citations Open access
Semantic Scholar
Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures
Di Yu, C. Jin, Mohanraj Ramachandran, Jing Xu +10 more
2013PLoS ONE38 citations Open access
Semantic Scholar
Short and Long Term Clinical and Immunologic Follow up after Bone Marrow Mesenchymal Stromal Cell Therapy in Progressive Multiple Sclerosis—A Phase I Study
Ellen Iacobaeus, N. Kadri, Katia Lefsihane, E. Boberg +5 more
2019Journal of Clinical Medicine34 citations Open access
Semantic Scholar
Do Cryopreserved Mesenchymal Stromal Cells Display Impaired Immunomodulatory and Therapeutic Properties?
Guido Moll, J. Alm, L. Davies, L. von Bahr +12 more
2014Stem Cells31 citations Open access
Semantic Scholar
White Paper on How to Go Forward with Cell-Based Advanced Therapies in Europe
R. Erben, B. Silva‐Lima, I. Reischl, Prof. Dr. med. Gustav Steinhoff +7 more
2014Tissue Engineering. Part A28 citations Open access
Semantic Scholar
Consensus International Council for Commonality in Blood Banking Automation-International Society for Cell & Gene Therapy statement on standard nomenclature abbreviations for the tissue of origin of mesenchymal stromal cells.
S. Viswanathan, R. Ciccocioppo, J. Galipeau, M. Krampera +10 more
2021Cytotherapy27 citations Open access
Semantic Scholar
Heparinization of cell surfaces with short peptide-conjugated PEG-lipid regulates thromboinflammation in transplantation of human MSCs and hepatocytes.
Sana Asif, K. Ekdahl, K. Fromell, Elisabet Gustafson +4 more
2016Acta Biomaterialia25 citations
Semantic Scholar
Factors With an Impact on Chimerism Development and Long-Term Survival After Umbilical Cord Blood Transplantation
S. Berglund, K. Le Blanc, M. Remberger, J. Gertow +7 more
2012Transplantation25 citations Open access
Semantic Scholar
Transcriptomic and proteomic profiles of fetal versus adult mesenchymal stromal cells and mesenchymal stromal cell-derived extracellular vesicles
Emine Gencer, Yuk Kit Lor, F. Abomaray, S. el Andaloussi +9 more
2024Stem cell research & therapeutics24 citations Open access
Semantic Scholar
Treatment of Chronic GvHD with Mesenchymal Stromal Cells Induces Durable Responses; A Phase II Study
L. von Bahr, L. Davies, G. Afram, C. Modin +4 more
201523 citations
Semantic Scholar
Mesenchymal stromal cells support endothelial cell interactions in an intramuscular islet transplantation model
M. Fransson, Johan Brännström, I. Duprez, M. Essand +3 more
2015Regenerative Medicine Research23 citations Open access
Semantic Scholar
An International Society for Cell and Gene Therapy Mesenchymal Stromal Cells (MSC) Committee perspectives on International Standards Organization/Technical Committee 276 Biobanking Standards for bone marrow-MSCs and umbilical cord tissue-derived MSCs for research purposes.
S. Viswanathan, K. Le Blanc, R. Ciccocioppo, Georges Dagher +11 more
2023Cytotherapy21 citations Open access
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