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D. Depledge · SciRah

Researcher profile · Semantic Scholar

D. Depledge

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D. Depledge — researcher profile on SciRah

h-index: 33
Works: 103
Citations: 5,890

Most-cited papers

TriTrypDB: a functional genomic resource for the Trypanosomatidae
M. Aslett, C. Aurrecoechea, M. Berriman, John E. Brestelli +40 more
2009Nucleic Acids Res.978 citations Open access
Semantic Scholar
Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania.
Matthew B. Rogers, J. Hilley, N. Dickens, J. Wilkes +14 more
2011Genome Research454 citations Open access
Semantic Scholar
Rapid Whole-Genome Sequencing of Mycobacterium tuberculosis Isolates Directly from Clinical Samples
A. C. Brown, J. Bryant, K. Einer-Jensen, J. Holdstock +18 more
2015Journal of Clinical Microbiology298 citations Open access
Semantic Scholar
Specific Capture and Whole-Genome Sequencing of Viruses from Clinical Samples
D. Depledge, A. Palser, S. Watson, I. Y. Lai +6 more
2011PLoS ONE223 citations Open access
Semantic Scholar
Direct RNA sequencing on nanopore arrays redefines the transcriptional complexity of a viral pathogen
D. Depledge, K. P. Srinivas, Tomohiko Sadaoka, Devin Bready +4 more
2019Nature Communications208 citations Open access
Semantic Scholar
ICTV Virus Taxonomy Profile: Herpesviridae 2021
D. Gatherer, D. Depledge, C. Hartley, Moriah L. Szpara +21 more
2021Journal of General Virology203 citations Open access
Semantic Scholar
RNA m6 A modification enzymes shape innate responses to DNA by regulating interferon β
R. M. Rubio, D. Depledge, C. Bianco, Letitia Thompson +1 more
2018Genes & Development202 citations Open access
Semantic Scholar
Viral population analysis and minority-variant detection using short read next-generation sequencing
S. Watson, M. Welkers, D. Depledge, E. Coulter +3 more
2013Philosophical Transactions of the Royal Society B: Biological Sciences197 citations Open access
Semantic Scholar
Direct RNA sequencing reveals m6A modifications on adenovirus RNA are necessary for efficient splicing
Alexander M. Price, Katharina E. Hayer, Alexa B. R. McIntyre, Nandan S. Gokhale +7 more
2019Nature Communications185 citations Open access
Semantic Scholar
Targeting the m6A RNA modification pathway blocks SARS-CoV-2 and HCoV-OC43 replication
Hannah M. Burgess, D. Depledge, Letitia Thompson, K. P. Srinivas +10 more
2021Genes & Development123 citations Open access
Semantic Scholar
Human cytomegalovirus haplotype reconstruction reveals high diversity due to superinfection and evidence of within-host recombination
Juliana Cudini, Sunando Roy, C. Houldcroft, J. Bryant +8 more
2019Proceedings of the National Academy of Sciences of the United States of America111 citations Open access
Semantic Scholar
Deep Sequencing of Viral Genomes Provides Insight into the Evolution and Pathogenesis of Varicella Zoster Virus and Its Vaccine in Humans
D. Depledge, S. Kundu, Nancy J. Jensen, E. Gray +8 more
2013Molecular biology and evolution103 citations Open access
Semantic Scholar
A spliced latency-associated VZV transcript maps antisense to the viral transactivator gene 61
D. Depledge, Werner J. D. Ouwendijk, Tomohiko Sadaoka, Shirley E. Braspenning +4 more
2018Nature Communications102 citations Open access
Semantic Scholar
Next-generation whole genome sequencing identifies the direction of norovirus transmission in linked patients.
S. Kundu, J. Lockwood, D. Depledge, Yasmin Chaudhry +5 more
2013Clinical Infectious Diseases89 citations Open access
Semantic Scholar
Molecular Aspects of Varicella-Zoster Virus Latency
D. Depledge, Tomohiko Sadaoka, Werner J. D. Ouwendijk
2018Viruses87 citations Open access
Semantic Scholar
Islands of linkage in an ocean of pervasive recombination reveals two-speed evolution of human cytomegalovirus genomes
Florent Lassalle, D. Depledge, M. Reeves, A. C. Brown +15 more
2016Virus Evolution85 citations Open access
Semantic Scholar
Whole-genome enrichment and sequencing of Chlamydia trachomatisdirectly from clinical samples
M. Christiansen, A. C. Brown, S. Kundu, H. Tutill +10 more
2014BMC Infectious Diseases85 citations Open access
Semantic Scholar
Detection of Low Frequency Multi-Drug Resistance and Novel Putative Maribavir Resistance in Immunocompromised Pediatric Patients with Cytomegalovirus
C. Houldcroft, J. Bryant, D. Depledge, Ben K. Margetts +9 more
2016Frontiers in Microbiology81 citations Open access
Semantic Scholar
Widespread remodeling of the m6A RNA-modification landscape by a viral regulator of RNA processing and export
K. P. Srinivas, D. Depledge, Jonathan S. Abebe, S. Rice +2 more
2021Proceedings of the National Academy of Sciences of the United States of America78 citations Open access
Semantic Scholar
Recombination of Globally Circulating Varicella-Zoster Virus
P. Norberg, D. Depledge, S. Kundu, C. Atkinson +14 more
2015Journal of Virology75 citations Open access
Semantic Scholar
In vitro system using human neurons demonstrates that varicella-zoster vaccine virus is impaired for reactivation, but not latency
Tomohiko Sadaoka, D. Depledge, Labchan Rajbhandari, A. Venkatesan +2 more
2016Proceedings of the National Academy of Sciences of the United States of America71 citations Open access
Semantic Scholar
DRUMMER—rapid detection of RNA modifications through comparative nanopore sequencing
Jonathan S. Abebe, Alexander M. Price, Katharina E. Hayer, I. Mohr +3 more
2022Bioinform.62 citations Open access
Semantic Scholar
Enteric viruses evoke broad host immune responses resembling those elicited by the bacterial microbiome
S. Dallari, T. Heaney, Adriana Rosas-Villegas, J. Neil +7 more
2021Cell Host and Microbe52 citations Open access
Semantic Scholar
Use of Whole-Genome Sequencing of Adenovirus in Immunocompromised Pediatric Patients to Identify Nosocomial Transmission and Mixed-Genotype Infection
C. Houldcroft, Sunando Roy, S. Morfopoulou, Ben K. Margetts +11 more
2018Journal of Infectious Diseases50 citations Open access
Semantic Scholar
Decoding the Architecture of the Varicella-Zoster Virus Transcriptome
Shirley E. Braspenning, Tomohiko Sadaoka, J. Breuer, G. Verjans +2 more
2020mBio45 citations Open access
Semantic Scholar
Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6
Alexander L. Greninger, G. Knudsen, Pavitra Roychoudhury, Derek J. Hanson +16 more
2018BMC Genomics45 citations Open access
Semantic Scholar
Deep Sequencing of Distinct Preparations of the Live Attenuated Varicella-Zoster Virus Vaccine Reveals a Conserved Core of Attenuating Single-Nucleotide Polymorphisms
D. Depledge, K. Yamanishi, Yasuyuki Gomi, A. Gershon +1 more
2016Journal of Virology42 citations Open access
Semantic Scholar
Leishmania-Specific Surface Antigens Show Sub-Genus Sequence Variation and Immune Recognition
D. Depledge, Lorna M MacLean, Michael R. Hodgkinson, Barbara A. Smith +4 more
2010PLoS Neglected Tropical Diseases40 citations Open access
Semantic Scholar
Going the Distance: Optimizing RNA-Seq Strategies for Transcriptomic Analysis of Complex Viral Genomes
D. Depledge, I. Mohr, A. Wilson
2018Journal of Virology39 citations Open access
Semantic Scholar
Varicella-zoster virus VLT-ORF63 fusion transcript induces broad viral gene expression during reactivation from neuronal latency
Werner J. D. Ouwendijk, D. Depledge, Labchan Rajbhandari, Tihana Lenac Rovis +5 more
2020Nature Communications38 citations Open access
Semantic Scholar
Nanopore-Based Detection of Viral RNA Modifications
Jonathan S. Abebe, R. Verstraten, D. Depledge
2022mBio35 citations Open access
Semantic Scholar
Chromatin dynamics and the transcriptional competence of HSV-1 genomes during lytic infections
MiYao Hu, D. Depledge, Esteban Flores Cortes, J. Breuer +1 more
2019PLoS Pathogens35 citations Open access
Semantic Scholar
Evolution of Cocirculating Varicella-Zoster Virus Genotypes during a Chickenpox Outbreak in Guinea-Bissau
D. Depledge, E. Gray, S. Kundu, S. Cooray +3 more
2014Journal of Virology33 citations Open access
Semantic Scholar
Rates of Vaccine Evolution Show Strong Effects of Latency: Implications for Varicella Zoster Virus Epidemiology
L. Weinert, D. Depledge, S. Kundu, A. Gershon +4 more
2015Molecular biology and evolution30 citations Open access
Semantic Scholar
tRNA epitranscriptome determines pathogenicity of the opportunistic pathogen Pseudomonas aeruginosa
J. Krueger, Matthias Preusse, Nicolas Oswaldo Gomez, Y. N. Frommeyer +13 more
2024Proceedings of the National Academy of Sciences of the United States of America29 citations Open access
Semantic Scholar
Novel viral splicing events and open reading frames revealed by long-read direct RNA sequencing of adenovirus transcripts
Alexander M. Price, R. Steinbock, Richard Lauman, Matthew Charman +9 more
2022PLoS Pathogens29 citations Open access
Semantic Scholar
High Viral Diversity and Mixed Infections in Cerebral Spinal Fluid From Cases of Varicella Zoster Virus Encephalitis
D. Depledge, Juliana Cudini, S. Kundu, C. Atkinson +14 more
2018Journal of Infectious Diseases29 citations Open access
Semantic Scholar
Acute Retinal Necrosis Caused by the Zoster Vaccine Virus
G. Heath, D. Depledge, Julianne R. Brown, Anthony D. Hale +3 more
2017Clinical Infectious Diseases27 citations Open access
Semantic Scholar
Coevolution of Sites under Immune Selection Shapes Epstein–Barr Virus Population Structure
Fanny Wegner, Florent Lassalle, D. Depledge, F. Balloux +1 more
2019Molecular biology and evolution25 citations Open access
Semantic Scholar
Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America
Joshua G. Tweedy, M. Spyrou, Callum D. Donaldson, D. Depledge +2 more
2015Genome Announcements25 citations Open access
Semantic Scholar
DLK-Dependent Biphasic Reactivation of Herpes Simplex Virus Latency Established in the Absence of Antivirals
Sara A. Dochnal, Husain Y. Merchant, Austin R. Schinlever, Aleksandra W Babnis +3 more
2022Journal of Virology24 citations Open access
Semantic Scholar
Single‐cell transcriptomics identifies Gadd45b as a regulator of herpesvirus‐reactivating neurons
Hui-Lan Hu, K. P. Srinivas, Shuo-Shuo Wang, M. Chao +5 more
2021EMBO Reports23 citations Open access
Semantic Scholar
An eIF3d-dependent switch regulates HCMV replication by remodeling the infected cell translation landscape to mimic chronic ER stress
Letitia Thompson, D. Depledge, Hannah M. Burgess, I. Mohr
2022Cell Reports21 citations Open access
Semantic Scholar
Viral Genome Sequencing Proves Nosocomial Transmission of Fatal Varicella
D. Depledge, Julianne R. Brown, J. Macanovic, G. Underhill +1 more
2016Journal of Infectious Diseases20 citations Open access
Semantic Scholar
Kallikrein-mediated cytokeratin 10 degradation is required for VZV propagation in skin.
C. Tommasi, C. Rogerson, D. Depledge, Meleri Jones +7 more
2020Journal of Investigative Dermatology19 citations Open access
Semantic Scholar
Whole genome sequencing of Herpes Simplex Virus 1 directly from human cerebrospinal fluid reveals selective constraints in neurotropic viruses
Florent Lassalle, M. Beale, T. Bharucha, C. Williams +6 more
2019bioRxiv17 citations Open access
Semantic Scholar
Mode of Virus Rescue Determines the Acquisition of VHS Mutations in VP22-Negative Herpes Simplex Virus 1
K. Ebert, D. Depledge, J. Breuer, Laura E R Harman +1 more
2013Journal of Virology15 citations Open access
Semantic Scholar
Analysis of the reiteration regions (R1 to R5) of varicella-zoster virus
Nancy J. Jensen, D. Depledge, T. Ng, Jessica W. Leung +8 more
2020Virology14 citations Open access
Semantic Scholar
Recurrent herpes zoster in the Shingles Prevention Study: Are second episodes caused by the same varicella-zoster virus strain?
R. Harbecke, N. Jensen, D. Depledge, G. Johnson +5 more
2020Vaccine14 citations Open access
Semantic Scholar
A Variant Allele in Varicella-Zoster Virus Glycoprotein B Selected during Production of the Varicella Vaccine Contributes to Its Attenuation
Tomohiko Sadaoka, D. Depledge, Labchan Rajbhandari, J. Breuer +2 more
2022mBio13 citations Open access
Semantic Scholar

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