Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Liang-Liang Shen · SciRah

Researcher profile · Semantic Scholar

Liang-Liang Shen

Share profile

Liang-Liang Shen — researcher profile on SciRah

h-index: 20
Works: 43
Citations: 1,293

Most-cited papers

Metabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIP
Liang-Liang Shen, John M O'Shea, Mohan R. Kaadige, S. Cunha +4 more
2015Proceedings of the National Academy of Sciences of the United States of America211 citations Open access
Semantic Scholar
MiRNA-29b suppresses tumor growth through simultaneously inhibiting angiogenesis and tumorigenesis by targeting Akt3.
Yan Li, B. Cai, Liang-Liang Shen, Yan Dong +6 more
2017Cancer Letters119 citations
Semantic Scholar
Tumor suppressor NDRG2 tips the balance of oncogenic TGF-β via EMT inhibition in colorectal cancer
Liang-Liang Shen, X. Qu, Yongzheng Ma, Jianyong Zheng +8 more
2014Oncogenesis81 citations Open access
Semantic Scholar
Baicalin Protects the Cardiomyocytes from ER Stress-Induced Apoptosis: Inhibition of CHOP through Induction of Endothelial Nitric Oxide Synthase
Min Shen, Lin Wang, Guo-Dong Yang, Lei Gao +11 more
2014PLoS ONE68 citations Open access
Semantic Scholar
NDRG2 facilitates colorectal cancer differentiation through the regulation of Skp2-p21/p27 axis
Liang-Liang Shen, X. Qu, Huichen Li, Chun-Sheng Xu +16 more
2018Oncogene67 citations Open access
Semantic Scholar
Activation of volume-sensitive outwardly rectifying chloride channel by ROS contributes to ER stress and cardiac contractile dysfunction: involvement of CHOP through Wnt
Min Shen, Liang Wang, Bo Wang, Tao Wang +7 more
2014Cell Death and Disease65 citations Open access
Semantic Scholar
Loss of NDRG2 in liver microenvironment inhibits cancer liver metastasis by regulating tumor associate macrophages polarization
Mengyang Li, X. Lai, Ying-Yue Zhao, Yuan Zhang +12 more
2018Cell Death and Disease56 citations Open access
Semantic Scholar
Chronic inflammation confers to the metabolic reprogramming associated with tumorigenesis of colorectal cancer
Dingding Qu, Liang-Liang Shen, Shaoqing Liu, Huichen Li +6 more
2017Cancer Biology & Therapy52 citations Open access
Semantic Scholar
c-Myc Overexpression Promotes Oral Cancer Cell Proliferation and Migration by Enhancing Glutaminase and Glutamine Synthetase Activity.
Tao Wang, Bo-Lei Cai, M. Ding, Zhong-Zhou Su +2 more
2019American Journal of the Medical Sciences49 citations
Semantic Scholar
A signal transduction pathway from TGF-β1 to SKP2 via Akt1 and c-Myc and its correlation with progression in human melanoma.
X. Qu, Liang-Liang Shen, Yan Zheng, Yang Cui +3 more
2014Journal of Investigative Dermatology49 citations Open access
Semantic Scholar
c-Myc-driven glycolysis via TXNIP suppression is dependent on glutaminase-MondoA axis in prostate cancer.
X. Qu, Jing Sun, Ya-Mi Zhang, Jun Li +4 more
2018Biochemical and Biophysical Research Communications - BBRC48 citations
Semantic Scholar
NDRG2 regulates adherens junction integrity to restrict colitis and tumourigenesis
Meng-Ying Wei, Yongzheng Ma, Liang-Liang Shen, Yuqiao Xu +10 more
2020EBioMedicine44 citations Open access
Semantic Scholar
Biological role of metabolic reprogramming of cancer cells during epithelial‑mesenchymal transition (Review).
Ming-Zhe Li, X. Bu, B. Cai, Ping Liang +3 more
2018Oncology Report38 citations Open access
Semantic Scholar
Degradation of HER2 by Cbl-based chimeric ubiquitin ligases.
Xia Li, Liang-Liang Shen, Jing Zhang, Jin Su +5 more
2007Cancer Research38 citations Open access
Semantic Scholar
miR-647 and miR-1914 promote cancer progression equivalently by downregulating nuclear factor IX in colorectal cancer
Shaoqing Liu, Dingding Qu, Weiping Li, Chen-Xiang He +6 more
2017Molecular Medicine Reports31 citations Open access
Semantic Scholar
Glucose- and glutamine-dependent bioenergetics sensitize bone mechanoresponse after unloading by modulating osteocyte calcium dynamics
Xiyu Liu, Ze-Dong Yan, Jing Cai, Dan Wang +9 more
2022Journal of Clinical Investigation30 citations Open access
Semantic Scholar
CD147 confers temozolomide resistance of glioma cells via the regulation of β-TrCP/Nrf2 pathway
X. Bu, X. Qu, Kai Guo, Xiangliang Meng +13 more
2021International Journal on Biological Sciences28 citations Open access
Semantic Scholar
High-specificity protection against radiation-induced bone loss by a pulsed electromagnetic field
Ze-Dong Yan, Dan Wang, Jing Cai, Liang-Liang Shen +6 more
2022Science Advances24 citations Open access
Semantic Scholar
Tg737 regulates epithelial-mesenchymal transition and cancer stem cell properties via a negative feedback circuit between Snail and HNF4α during liver stem cell malignant transformation.
Qike Huang, Meng Pu, Ge Zhao, Bin Dai +7 more
2017Cancer Letters24 citations
Semantic Scholar
Rescuing SERCA2 pump deficiency improves bone mechano-responsiveness in type 2 diabetes by shaping osteocyte calcium dynamics
Xi Shao, Yulan Tian, Juan Liu, Ze-Dong Yan +10 more
2024Nature Communications21 citations Open access
Semantic Scholar
NDRG2 ablation reprograms metastatic cancer cells towards glutamine dependence via the induction of ASCT2
M. Ding, X. Bu, Zhehao Li, Haokun Xu +9 more
2020International Journal on Biological Sciences20 citations Open access
Semantic Scholar
Discovery of a novel protein kinase B inhibitor by structure-based virtual screening.
J. Medina-Franco, M. Giulianotti, Yong-Ping Yu, Liang-Liang Shen +2 more
2009Bioorganic & Medicinal Chemistry Letters19 citations Open access
Semantic Scholar
BCR-ABL triggers a glucose-dependent survival program during leukemogenesis through the suppression of TXNIP
Lin-Xi Feng, Ruxin Ding, X. Qu, Yuan-Chun Li +11 more
2023Cell Death and Disease18 citations Open access
Semantic Scholar
Colorectal Cancer Cell Differentiation Is Dependent on the Repression of Aerobic Glycolysis by NDRG2-TXNIP Axis
Jun-Bi Hu, Lin Feng, Mu-Dan Ren, Yan Zhao +8 more
2021Digestive Diseases and Sciences16 citations
Semantic Scholar
Nuclear translocation of MRP1 contributes to multidrug resistance of mucoepidermoid carcinoma.
Bo-Lei Cai, Xiao-Fang Xu, Shan-Min Fu, Liang-Liang Shen +3 more
2011Oral Oncology16 citations
Semantic Scholar
Inducing differentiation of human urine‐derived stem cells into hepatocyte‐like cells by coculturing with human hepatocyte L02 cells
M. Zhou, Liang-Liang Shen, Yinggu Qiao, Zhen-Xiao Sun
2020Journal of Cellular Biochemistry11 citations Open access
Semantic Scholar
High Throughput Transcriptome Data Analysis and Computational Verification Reveal Immunotherapy Biomarkers of Compound Kushen Injection for Treating Triple-Negative Breast Cancer
Xin-Kui Liu, Yang Wu, Yingying Zhang, D. Bu +13 more
2021Frontiers in Oncology10 citations Open access
Semantic Scholar
BRAFV600E dictates cell survival via c-Myc-dependent induction of Skp2 in human melanoma.
Lin Feng, Jun Li, X. Bu, Y. Zuo +2 more
2020Biochemical and Biophysical Research Communications - BBRC10 citations
Semantic Scholar
Hedgehog pathway is negatively regulated during the development of Drosophila melanogaster PheRS-m (Drosophila homologs gene of human FARS2) mutants
Lidangzhi Mo, Rui Li, Chunxia He, Qi Chen +4 more
2022Human Cell7 citations
Semantic Scholar
Nuclear Multidrug Resistance-Related Protein 1 Is Highly Associated with Better Prognosis of Human Mucoepidermoid Carcinoma through the Suppression of Cell Proliferation, Migration and Invasion
Bo-Lei Cai, Yan Li, Liang-Liang Shen, Jin-Long Zhao +4 more
2016PLoS ONE6 citations Open access
Semantic Scholar
Rapid Detection of Streptococcus mutans Using an Integrated Microfluidic System with Loop-Mediated Isothermal Amplification
Jing-Fu Wang, Jing-Yi Wang, Xin Chang, Jin-cheng Shang +3 more
2023Journal of Microbiology and Biotechnology5 citations Open access
Semantic Scholar
miR-647 and miR-1914 promote cancer progression equivalently by downregulating nuclear factor IX in colorectal cancer
Shaoqing Liu, Dingding Qu, Weiping Li, Chen-Xiang He +6 more
2022Molecular Medicine Reports4 citations Open access
Semantic Scholar
NDRG4 sensitizes CRC cells to 5-FU by upregulating DDIT3 expression
Rui-Kai Li, Chen-Xiang He, Liang-Liang Shen, Shuai Wang +4 more
2022Oncology Letters4 citations Open access
Semantic Scholar
NDRG 2: On the Path to Cell Stress and Cancer
Liang-Liang Shen, Li-Bo Yao, Jian Zhang
20152 citations
Semantic Scholar
NDRG2 orchestrates circadian clock stability to suppress tumorigenesis and potentiate oxaliplatin response in colorectal cancer
Rui-Kai Li, Ruxin Ding, Han-Long Dan, Kunli Du +19 more
2026Oncogene1 citations
Semantic Scholar
IGF2BP3-dependent glutamine/BCAA metabolic rewiring rejuvenates aged human adipose-derived stem cells for enhanced tissue regeneration
Zichao Li, Lin Feng, Xinxin Wei, Hui-cheng Li +8 more
2026Cell Discovery1 citations Open access
Semantic Scholar
NDRG2 Regulates Adherens Junction Integrity to Restrict Colitis and Tumorigenesis
Meng-Ying Wei, Yongzheng Ma, Liang-Liang Shen, Yuqiao Xu +10 more
2018bioRxiv1 citations Open access
Semantic Scholar
NDRG4 sensitizes CRC cells to 5-FU by upregulating DDIT3 expression
Rui-Kai Li, Chen-Xiang He, Liang-Liang Shen, Shuai Wang +4 more
2021Oncology Letters0 citations Open access
Semantic Scholar
N-Myc Downstream-Regulated Gene 2 (NDRG2) as a Novel Tumor Suppressor in Multiple Human Cancers
Jian Zhang, Xia Li, Liang-Liang Shen, Yan Li +1 more
2019Genes & cancer0 citations Open access
Semantic Scholar
Loss of NDRG2 in liver microenvironment inhibits cancer liver metastasis by regulating tumor associate macrophages polarization
Mengyang Li, X. Lai, Ying-Ling Zhao, Yuan Zhang +12 more
2018Cell Death and Disease0 citations Open access
Semantic Scholar
CHOP-eNOS pathway in baicalin mediated protective role.
Min Shen, Lin Wang, Guo-don Yang, Lei Gao +11 more
20140 citations Open access
Semantic Scholar
Title A signal transduction pathway from TGF-β 1 to SKP 2 via Akt 1 and c-Myc and its correlation with progression in human melanoma
X. Qu, Liang-Liang Shen, Yan Zheng, Yang Cui +3 more
20130 citations
Semantic Scholar
重组泛素连接酶PTB-U-box/RING的构建与表达
Qin-Hao Wang, Yi Ru, Liang-Liang Shen, Xia Li +1 more
20110 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

Li-Bo Yao×12
Invite
Li-Bo Yao — researcher profile on SciRah
Jian Zhang×11
Invite
Jian Zhang — researcher profile on SciRah
X. Qu×10
Invite
X. Qu — researcher profile on SciRah
X. Bu×8
Invite
X. Bu — researcher profile on SciRah

×5

Invite

Yongzheng Ma — researcher profile on SciRah

Jianyong Zheng×5

Invite

Jianyong Zheng — researcher profile on SciRah

Invite

Ji-Peng Li — researcher profile on SciRah

Invite

Huichen Li — researcher profile on SciRah

Invite

Jun-Bi Hu — researcher profile on SciRah

Invite

Kai-Chun Wu — researcher profile on SciRah

Invite

Yan-Pu Liu — researcher profile on SciRah

Chen-Xiang He×4

Invite

Chen-Xiang He — researcher profile on SciRah