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A. Droop · SciRah

Researcher profile · Semantic Scholar

A. Droop

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A. Droop — researcher profile on SciRah

h-index: 20
Works: 81
Citations: 1,989

Most-cited papers

Genomic Subtypes of Non-Invasive Bladder Cancer with Distinct Metabolic Profile, Clinical Outcome and Female Gender Bias in KDM6A Mutation Frequency
C. Hurst, Olivia Alder, F. Platt, A. Droop +14 more
2017Cancer Cell262 citations Open access
Semantic Scholar
Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions
R. Birnie, Steven D. Bryce, Claire Roome, V. Dussupt +8 more
2008Genome Biology225 citations Open access
Semantic Scholar
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa
A. Buskin, Lili Zhu, V. Chichagova, Basudha Basu +38 more
2018Nature Communications193 citations Open access
Semantic Scholar
The mutational signature profile of known and suspected human carcinogens in mice
L. Riva, A. Pandiri, Y. Li, A. Droop +10 more
2020Nature Genetics133 citations Open access
Semantic Scholar
Combinatorial CRISPR screen identifies fitness effects of gene paralogues
Nicola A. Thompson, M. Ranzani, L. van der Weyden, V. Iyer +18 more
2021Nature Communications118 citations Open access
Semantic Scholar
β-Catenin–mediated immune evasion pathway frequently operates in primary cutaneous melanomas
J. Nsengimana, Jon P. Laye, A. Filia, S. O'Shea +14 more
2018Journal of Clinical Investigation94 citations Open access
Semantic Scholar
KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice
E. Polson, Verena B. Kuchler, C. Abbosh, Edith M. Ross +22 more
2018Science Translational Medicine74 citations Open access
Semantic Scholar
Yeast Ntr1/Spp382 Mediates Prp43 Function in Postspliceosomes
Kum-loong Boon, Tatsiana Auchynnikava, G. Edwalds-Gilbert, J. Barrass +3 more
2006Molecular and Cellular Biology67 citations
Semantic Scholar
Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma
H. J. Close, Lucy F. Stead, J. Nsengimana, Katrina Reilly +9 more
2019bioRxiv66 citations Open access
Semantic Scholar
Prediction of clinical outcome in glioblastoma using a biologically relevant nine‐microRNA signature
J. Hayes, H. Thygesen, Charlotte A. Tumilson, A. Droop +7 more
2015Molecular Oncology61 citations Open access
Semantic Scholar
Genetic and environmental determinants of immune response to cutaneous melanoma
J. Pozniak, J. Nsengimana, Jon P. Laye, S. O'Shea +14 more
2019Cancer Research52 citations Open access
Semantic Scholar
The clinicopathologic spectrum and genomic landscape of de-/trans-differentiated melanoma
I. Ferreira, A. Droop, O. Edwards, K. Wong +19 more
2021Modern Pathology44 citations Open access
Semantic Scholar
Elucidating drivers of oral epithelial dysplasia formation and malignant transformation to cancer using RNAseq
C. Conway, J. Graham, P. Chengot, C. Daly +5 more
2015OncoTarget41 citations Open access
Semantic Scholar
Retinoic acid and androgen receptors combine to achieve tissue specific control of human prostatic transglutaminase expression: a novel regulatory network with broader significance
Guillermo C. Rivera-Gonzalez, A. Droop, H. Rippon, K. Tiemann +3 more
2012Nucleic Acids Research35 citations Open access
Semantic Scholar
Sequence analysis fqtools: an efficient software suite for modern FASTQ file manipulation
A. Droop
201633 citations
Semantic Scholar
The calcium sensor STIM1 is regulated by androgens in prostate stromal cells
P. Berry, R. Birnie, A. Droop, N. Maitland +1 more
2011The Prostate31 citations
Semantic Scholar
Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia
Emmanuelle Supper, S. Rudat, V. Iyer, A. Droop +6 more
2021Nature Communications27 citations Open access
Semantic Scholar
Benchmarking pipelines for subclonal deconvolution of bulk tumour sequencing data
Georgette Tanner, D. Westhead, A. Droop, Lucy F. Stead
2021Nature Communications27 citations Open access
Semantic Scholar
Engineering Simulations as Scientific Instruments: A Pattern Language
S. Stepney, F. Polack, K. Alden, P. Andrews +7 more
2018Cambridge International Law Journal26 citations Open access
Semantic Scholar
Biglycan and reduced glycolysis are associated with breast cancer cell dormancy in the brain
Ashley Sunderland, Jennifer Williams, Tereza Andreou, Nora Rippaus +7 more
2023Frontiers in Oncology22 citations Open access
Semantic Scholar
Hematopoietic Stem Cell Gene Therapy for Brain Metastases Using Myeloid Cell–Specific Gene Promoters
Tereza Andreou, Nora Rippaus, Krzysztof Wroński, Jennifer Williams +11 more
2019Journal of the National Cancer Institute20 citations Open access
Semantic Scholar
Analysis of CRISPR‐Cas9 screens identifies genetic dependencies in melanoma
Eirini Christodoulou, Mamunur Rashid, C. Pacini, A. Droop +7 more
2020Pigment Cell & Melanoma Research19 citations Open access
Semantic Scholar
Stanniocalcin 2 expression is associated with a favourable outcome in male breast cancer
Camilla Coulson-Gilmer, M. Humphries, Sreekumar Sundara Rajan, A. Droop +13 more
2018The Journal of Pathology: Clinical Research19 citations Open access
Semantic Scholar
RNA sequencing and functional studies of patient-derived cells reveal that neurexin-1 and regulators of this pathway are associated with poor outcomes in Ewing sarcoma
E. Roundhill, M. Chicón-Bosch, L. Jeys, M. Parry +3 more
2021Cellular Oncology18 citations Open access
Semantic Scholar
Conserved Two-Step Regulatory Mechanism of Human Epithelial Differentiation
J. Rane, A. Droop, Davide Pellacani, E. Polson +4 more
2014Stem Cell Reports18 citations Open access
Semantic Scholar
Simulation validation: exploring the suitability of a simulation of cell division and differentiation in the prostate
F. Polack, A. Droop, Philip Garnett, Teodor Ghetiu +1 more
201118 citations
Semantic Scholar
A Case-Matched Gender Comparison Transcriptomic Screen Identifies eIF4E and eIF5 as Potential Prognostic Markers in Male Breast Cancer
M. Humphries, Sreekumar Sundara Rajan, A. Droop, Charlotte A. B. Suleman +28 more
2016Clinical Cancer Research17 citations Open access
Semantic Scholar
A quantitative measure of non-neutral evolutionary activity for systems that exhibit intrinsic fitness
A. Droop, S. Hickinbotham
2012IEEE Symposium on Artificial Life16 citations
Semantic Scholar
IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy
Georgette Tanner, Rhiannon Barrow, Shoaib Ajaib, M. Al-Jabri +26 more
2023bioRxiv15 citations Open access
Semantic Scholar
CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation
L. van der Weyden, V. Harle, Gemma Turner, Victoria Offord +13 more
2021Communications Biology15 citations Open access
Semantic Scholar
Phenotype-independent DNA methylation changes in prostate cancer
Davide Pellacani, A. Droop, F. Frame, M. Simms +4 more
2018British Journal of Cancer15 citations Open access
Semantic Scholar
Changes in plasma chemokine C-C motif ligand 2 levels during treatment with eicosapentaenoic acid predict outcome in patients undergoing surgery for colorectal cancer liver metastasis
Milene Volpato, Sarah L. Perry, G. Marston, N. Ingram +9 more
2016OncoTarget13 citations Open access
Semantic Scholar
Oncolytic virus treatment differentially affects the CD56dim and CD56bright NK cell subsets in vivo and regulates a spectrum of human NK cell activity
M. Wantoch, E. Wilson, A. Droop, S. L. Phillips +6 more
2020bioRxiv12 citations Open access
Semantic Scholar
Notch signalling is a potential resistance mechanism of progenitor cells within patient‐derived prostate cultures following ROS‐inducing treatments
John R. Packer, A. Hirst, A. Droop, R. Adamson +5 more
2019FEBS Letters11 citations Open access
Semantic Scholar
Prognostic microRNAs in high-grade glioma reveal a link to oligodendrocyte precursor differentiation
J. Hayes, H. Thygesen, A. Droop, T. Hughes +4 more
2014Oncoscience11 citations Open access
Semantic Scholar
Upregulated WEE1 protects endothelial cells of colorectal cancer liver metastases
P. J. Webster, A. Littlejohns, Hannah J. Gaunt, R. Young +16 more
2017OncoTarget10 citations Open access
Semantic Scholar
GSK-3 Inhibition Is Cytotoxic in Glioma Stem Cells through Centrosome Destabilization and Enhances the Effect of Radiotherapy in Orthotopic Models
A. Brüning-Richardson, G. Shaw, D. Tams, T. Brend +16 more
2021Cancers8 citations Open access
Semantic Scholar
High-Resolution Copy Number Patterns From Clinically Relevant FFPE Material
A. Filia, A. Droop, M. Harland, H. Thygesen +9 more
2019Scientific Reports8 citations Open access
Semantic Scholar
Chemically induced neurite-like outgrowth reveals a multicellular network function in patient-derived glioblastoma cells
Barbara da Silva, Bronwyn K. Irving, E. Polson, A. Droop +12 more
2018Journal of Cell Science8 citations Open access
Semantic Scholar
A Detailed Analysis of Gene Expression in Human Basal, Luminal, and Stromal Cell Populations from Benign Prostatic Hyperplasia Tissues and Comparisons with Cultured Basal Cells.
J. Rane, A. Droop, N. Maitland
2017European Urology8 citations Open access
Semantic Scholar
Multiple model simulation : modelling cell division and differentiation in the prostate
A. Droop, Philip Garnett, F. Polack, S. Stepney
20118 citations
Semantic Scholar
Profiling cytotoxic microRNAs in pediatric and adult glioblastoma cells by high-content screening, identification, and validation of miR-1300
M. Boissinot, H. King, M. Adams, J. Higgins +17 more
2020Oncogene7 citations Open access
Semantic Scholar
Simulation of heterogeneous tumour genomes with HeteroGenesis and in silico whole exome sequencing
Georgette Tanner, D. Westhead, A. Droop, Lucy F. Stead
2019Bioinform.7 citations Open access
Semantic Scholar
Identification of transcriptional targets of GSK3 involved in glioblastoma invasion
A. Brüning-Richardson, A. Droop, D. Tams, M. Boissinot +10 more
20187 citations Open access
Semantic Scholar
How to analyse the spatiotemporal tumour samples needed to investigate cancer evolution: A case study using paired primary and recurrent glioblastoma
A. Droop, Alexander F. Bruns, Georgette Tanner, Nora Rippaus +11 more
2018International Journal of Cancer6 citations Open access
Semantic Scholar
Human iPSC-derived RPE and retinal organoids reveal impaired alternative splicing of genes involved in pre-mRNA splicing in PRPF31 autosomal dominant retinitis pigmentosa
A. Buskin, Lili Zhu, V. Chichagova, Basudha Basu +34 more
2017bioRxiv6 citations Open access
Semantic Scholar
Properties of Biological Mutation Networks and Their Implications for ALife
A. Droop, S. Hickinbotham
2011Artificial Life6 citations
Semantic Scholar
ETS transcription factor ELF3 (ESE‐1) is a cell cycle regulator in benign and malignant prostate
Leanne K. Archer, F. Frame, H. Walker, A. Droop +6 more
2022FEBS Open Bio5 citations Open access
Semantic Scholar
Genomic Subtypes of Non-Invasive Bladder Cancer with Distinct Metabolic Profile, Clinical Outcome and Female Gender Bias in KDM6A Mutation Frequency
--Manuscript Draft, C. Hurst, Olivia Alder, F. Platt +27 more
20174 citations
Semantic Scholar
qsubsec: a lightweight template system for defining sun grid engine workflows
A. Droop
2015Bioinform.4 citations Open access
Semantic Scholar

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