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W. Nickel · SciRah

Researcher profile · Semantic Scholar

W. Nickel

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W. Nickel — researcher profile on SciRah

h-index: 51
Works: 110
Citations: 8,386

Most-cited papers

Mechanisms of regulated unconventional protein secretion
W. Nickel, C. Rabouille
2009Nature reviews. Molecular cell biology676 citations
Semantic Scholar
The mystery of nonclassical protein secretion. A current view on cargo proteins and potential export routes.
W. Nickel
2003European Journal of Biochemistry614 citations
Semantic Scholar
Unconventional Secretory Routes: Direct Protein Export Across the Plasma Membrane of Mammalian Cells
W. Nickel
2005Traffic : the International Journal of Intracellular Transport345 citations
Semantic Scholar
Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors.
Martina Bremser, W. Nickel, M. Schweikert, M. Ravazzola +5 more
1999Cell307 citations Open access
Semantic Scholar
Inflammasome-dependent IL-1β release depends upon membrane permeabilisation
Fátima Martín-Sánchez, C. Diamond, M. Zeitler, A. I. Gómez +12 more
2016Cell Death and Differentiation278 citations Open access
Semantic Scholar
Loss of ceramide synthase 3 causes lethal skin barrier disruption.
R. Jennemann, M. Rabionet, K. Gorgas, Sharon Epstein +11 more
2012Human Molecular Genetics276 citations Open access
Semantic Scholar
Diversity in unconventional protein secretion
C. Rabouille, V. Malhotra, W. Nickel
2012Journal of Cell Science273 citations Open access
Semantic Scholar
Functional architecture of an intracellular membrane t-SNARE
Ryouichi Fukuda, J. McNew, T. Weber, F. Parlati +4 more
2000Nature253 citations
Semantic Scholar
Regulated secretion of macrophage migration inhibitory factor is mediated by a non‐classical pathway involving an ABC transporter
O. Flieger, A. Engling, R. Bucala, H. Lue +2 more
2003FEBS Letters241 citations
Semantic Scholar
Unconventional Secretion Mediates the Trans-cellular Spreading of Tau.
Taxiarchis Katsinelos, M. Zeitler, Eleni Dimou, Andromachi Karakatsani +6 more
2018Cell Reports232 citations Open access
Semantic Scholar
Evidence for Segregation of Sphingomyelin and Cholesterol during Formation of Copi-Coated Vesicles
B. Brügger, R. Sandhoff, Sabine Wegehingel, K. Gorgas +5 more
2000Journal of Cell Biology230 citations Open access
Semantic Scholar
Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs.
W. Nickel, T. Weber, J. McNew, F. Parlati +2 more
1999Proceedings of the National Academy of Sciences of the United States of America198 citations Open access
Semantic Scholar
Cell-surface heparan sulfate proteoglycans are essential components of the unconventional export machinery of FGF-2
Christoph Zehe, A. Engling, Sabine Wegehingel, Tobias Schäfer +1 more
2006Proceedings of the National Academy of Sciences of the United States of America161 citations Open access
Semantic Scholar
The cancer antigen CA125 represents a novel counter receptor for galectin-1
Claudia Seelenmeyer, Sabine Wegehingel, J. Lechner, W. Nickel
2003Journal of Cell Science157 citations Open access
Semantic Scholar
Unconventional Secretion of Fibroblast Growth Factor 2 Is Mediated by Direct Translocation across the Plasma Membrane of Mammalian Cells
Tobias Schäfer, H. Zentgraf, Christoph Zehe, B. Brügger +2 more
2004Journal of Biological Chemistry156 citations Open access
Semantic Scholar
Unconventional mechanisms of protein transport to the cell surface of eukaryotic cells.
W. Nickel, M. Seedorf
2008Annual Review of Cell and Developmental Biology151 citations
Semantic Scholar
A Conserved, Lipid‐Mediated Sorting Mechanism of Yeast Ist2 and Mammalian STIM Proteins to the Peripheral ER
Ebru Ercan, F. Momburg, U. Engel, K. Temmerman +2 more
2009Traffic : the International Journal of Intracellular Transport131 citations Open access
Semantic Scholar
The Golgi-associated Protein p115 Mediates the Secretion of Macrophage Migration Inhibitory Factor (MIF)
M. Merk, J. Baugh, S. Zierow, L. Leng +10 more
2009Journal of Immunology128 citations Open access
Semantic Scholar
Recruitment to Golgi membranes of ADP‐ribosylation factor 1 is mediated by the cytoplasmic domain of p23
Daniel U. Gommel, Abdul R. Memon, Armin Heiss, F. Lottspeich +6 more
2001EMBO Journal125 citations Open access
Semantic Scholar
CDC42 switches IRSp53 from inhibition of actin growth to elongation by clustering of VASP
Andrea Disanza, Sara Bisi, M. Winterhoff, F. Milanesi +15 more
2013EMBO Journal124 citations Open access
Semantic Scholar
Cell surface counter receptors are essential components of the unconventional export machinery of galectin-1
Claudia Seelenmeyer, Sabine Wegehingel, I. Tews, M. Künzler +2 more
2005Journal of Cell Biology124 citations Open access
Semantic Scholar
A Direct Role for Phosphatidylinositol‐4,5‐bisphosphate in Unconventional Secretion of Fibroblast Growth Factor 2
K. Temmerman, Antje D. Ebert, Hans-Michael Müller, I. Sinning +2 more
2008Traffic : the International Journal of Intracellular Transport122 citations Open access
Semantic Scholar
Unconventional mechanisms of eukaryotic protein secretion.
Eleni Dimou, W. Nickel
2018Current Biology114 citations Open access
Semantic Scholar
Phosphatidylinositol 4,5-Bisphosphate (PI(4,5)P2)-dependent Oligomerization of Fibroblast Growth Factor 2 (FGF2) Triggers the Formation of a Lipidic Membrane Pore Implicated in Unconventional Secretion*
Julia P. Steringer, Stephanie Bleicken, Helena Andreas, Sonja Zacherl +9 more
2012Journal of Biological Chemistry112 citations Open access
Semantic Scholar
Vesicular transport: the core machinery of COPI recruitment and budding.
W. Nickel, B. Brügger, F. Wieland
2002Journal of Cell Science108 citations
Semantic Scholar
Biosynthetic FGF-2 is targeted to non-lipid raft microdomains following translocation to the extracellular surface of CHO cells
A. Engling, R. Backhaus, Carolin Stegmayer, Christoph Zehe +5 more
2002Journal of Cell Science106 citations Open access
Semantic Scholar
Unconventional protein secretion: membrane translocation of FGF-2 does not require protein unfolding
R. Backhaus, Christoph Zehe, Sabine Wegehingel, Angelika Kehlenbach +2 more
2004Journal of Cell Science94 citations
Semantic Scholar
Pathways of unconventional protein secretion.
W. Nickel
2010Current Opinion in Biotechnology93 citations
Semantic Scholar
Functional reconstitution of COPI coat assembly and disassembly using chemically defined components
Constanze Reinhard, M. Schweikert, F. Wieland, W. Nickel
2003Proceedings of the National Academy of Sciences of the United States of America93 citations Open access
Semantic Scholar
IFITM3 blocks influenza virus entry by sorting lipids and stabilizing hemifusion
Steffen Klein, Gonen Golani, F. Lolicato, Carmen Lahr +15 more
2023bioRxiv82 citations Open access
Semantic Scholar
The Unconventional Secretory Machinery of Fibroblast Growth Factor 2
W. Nickel
2011Traffic : the International Journal of Intracellular Transport80 citations Open access
Semantic Scholar
Tec‐Kinase‐Mediated Phosphorylation of Fibroblast Growth Factor 2 is Essential for Unconventional Secretion
Antje D. Ebert, Mareike Laußmann, Sabine Wegehingel, L. Kaderali +6 more
2010Traffic : the International Journal of Intracellular Transport80 citations Open access
Semantic Scholar
A novel flow cytometric assay to quantify interactions between proteins and membrane lipids This study was supported by the Collaborative Research Center 638 of the German Research Foundation. Published, JLR Papers in Press, January 14, 2009.
K. Temmerman, W. Nickel
2009Journal of Lipid Research76 citations Open access
Semantic Scholar
Unconventional secretion: an extracellular trap for export of fibroblast growth factor 2
W. Nickel
2007Journal of Cell Science76 citations Open access
Semantic Scholar
Key steps in unconventional secretion of fibroblast growth factor 2 reconstituted with purified components
Julia P. Steringer, S. Lange, Sabína Čujová, Radek Šachl +11 more
2017eLife73 citations Open access
Semantic Scholar
A role for ADP ribosylation factor in the control of cargo uptake during COPI‐coated vesicle biogenesis
Jörg Malsam, Daniel U. Gommel, F. Wieland, W. Nickel
1999FEBS Letters73 citations
Semantic Scholar
Unconventional secretion of fibroblast growth factor 2--a novel type of protein translocation across membranes?
Julia P. Steringer, Hans-Michael Müller, W. Nickel
2015Journal of Molecular Biology69 citations
Semantic Scholar
Unconventional secretion of fibroblast growth factor 2 and galectin‐1 does not require shedding of plasma membrane‐derived vesicles
Claudia Seelenmeyer, Carolin Stegmayer, W. Nickel
2008FEBS Letters67 citations
Semantic Scholar
Dynamin-related Protein 1 (Drp1) Promotes Structural Intermediates of Membrane Division*
Begoña Ugarte-Uribe, Hans-Michael Müller, Miki Otsuki, W. Nickel +1 more
2014Journal of Biological Chemistry65 citations Open access
Semantic Scholar
Oligomerization and Ca2+/calmodulin control binding of the ER Ca2+-sensors STIM1 and STIM2 to plasma membrane lipids
Rajesh Bhardwaj, Hans-Michael Müller, W. Nickel, M. Seedorf
2013Bioscience Reports65 citations Open access
Semantic Scholar
SH4-domain-induced plasma membrane dynamization promotes bleb-associated cell motility
Stella Tournaviti, Sebastian Hannemann, S. Terjung, T. Kitzing +6 more
2007Journal of Cell Science64 citations Open access
Semantic Scholar
HIV-Tat Protein Forms Phosphoinositide-dependent Membrane Pores Implicated in Unconventional Protein Secretion*
M. Zeitler, Julia P. Steringer, Hans-Michael Müller, Matthias P. Mayer +1 more
2015Journal of Biological Chemistry57 citations Open access
Semantic Scholar
A signal comprising a basic cluster and an amphipathic α-helix interacts with lipids and is required for the transport of Ist2 to the yeast cortical ER
Kiran Maass, M. Fischer, Markus Seiler, K. Temmerman +2 more
2009Journal of Cell Science57 citations
Semantic Scholar
Mechanisms of regulated unconventional protein secretion
W. Nickel, C. Rabouille
2009Nature reviews. Molecular cell biology57 citations Open access
Semantic Scholar
Formation of Disulfide Bridges Drives Oligomerization, Membrane Pore Formation, and Translocation of Fibroblast Growth Factor 2 to Cell Surfaces*
Hans-Michael Müller, Julia P. Steringer, Sabine Wegehingel, Stephanie Bleicken +9 more
2015Journal of Biological Chemistry56 citations Open access
Semantic Scholar
The Startling Properties of Fibroblast Growth Factor 2: How to Exit Mammalian Cells without a Signal Peptide at Hand*
Giuseppe La Venuta, M. Zeitler, Julia P. Steringer, Hans-Michael Müller +1 more
2015Journal of Biological Chemistry55 citations Open access
Semantic Scholar
A Direct Role for ATP1A1 in Unconventional Secretion of Fibroblast Growth Factor 2*
Sonja Zacherl, Giuseppe La Venuta, Hans-Michael Müller, Sabine Wegehingel +6 more
2014Journal of Biological Chemistry55 citations Open access
Semantic Scholar
Binding of Plasma Membrane Lipids Recruits the Yeast Integral Membrane Protein Ist2 to the Cortical ER
M. Fischer, K. Temmerman, Ebru Ercan, W. Nickel +1 more
2009Traffic : the International Journal of Intracellular Transport54 citations Open access
Semantic Scholar
A direct gateway into the extracellular space: Unconventional secretion of FGF2 through self-sustained plasma membrane pores.
Julia P. Steringer, W. Nickel
2018Seminars in Cell and Developmental Biology52 citations
Semantic Scholar
Direct transport across the plasma membrane of mammalian cells of Leishmania HASPB as revealed by a CHO export mutant
Carolin Stegmayer, Angelika Kehlenbach, Stella Tournaviti, Sabine Wegehingel +5 more
2005Journal of Cell Science52 citations Open access
Semantic Scholar

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