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S. Brand · SciRah

Researcher profile · Semantic Scholar

S. Brand

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S. Brand — researcher profile on SciRah

h-index: 65
Works: 241
Citations: 22K

Most-cited papers

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
L. Jostins, S. Ripke, R. Weersma, R. Duerr +102 more
2012Nature4,620 citations Open access
Semantic Scholar
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
I. Cleynen, G. Boucher, L. Jostins, L. Schumm +38 more
2016The Lancet709 citations Open access
Semantic Scholar
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
Jimmy Z. Liu, J. Hov, T. Folseraas, E. Ellinghaus +80 more
2013Nature Genetics392 citations Open access
Semantic Scholar
Microbial network disturbances in relapsing refractory Crohn’s disease
B. Yilmaz, P. Juillerat, O. Øyås, Charlotte Ramon +45 more
2019Nature Medicine357 citations Open access
Semantic Scholar
Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment
C. Tillack, L. Ehmann, M. Friedrich, R. Laubender +16 more
2013Gut311 citations Open access
Semantic Scholar
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
Y. Momozawa, Julia Dmitrieva, E. Théâtre, V. Deffontaine +191 more
2018Nature Communications219 citations Open access
Semantic Scholar
Protective mucosal immunity mediated by epithelial CD1d and IL-10
T. Olszak, J. Neves, C. Dowds, K. Baker +18 more
2014Nature203 citations Open access
Semantic Scholar
High density genotyping study identifies four new susceptibility loci for atopic dermatitis
D. Ellinghaus, H. Baurecht, J. Esparza-Gordillo, E. Rodriguez +45 more
2013Nature Genetics197 citations Open access
Semantic Scholar
Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms
H. Baurecht, M. Hotze, S. Brand, C. Büning +34 more
2015American Journal of Human Genetics185 citations Open access
Semantic Scholar
Association Between Variants of PRDM1 and NDP52 and Crohn’s Disease, Based on Exome Sequencing and Functional Studies
D. Ellinghaus, Hu Zhang, S. Zeissig, S. Lipinski +57 more
2013Gastroenterology165 citations Open access
Semantic Scholar
A pleiotropic missense variant in SLC39A8 is associated with Crohn’s disease and human gut microbiome composition
Dalin Li, J. Achkar, T. Haritunians, J. Jacobs +36 more
2016Gastroenterology138 citations Open access
Semantic Scholar
Lipocalin-2 Is a Disease Activity Marker in Inflammatory Bowel Disease Regulated by IL-17A, IL-22, and TNF-&agr; and Modulated by IL23R Genotype Status
Johannes Stallhofer, M. Friedrich, A. Konrad-Zerna, Martin Wetzke +6 more
2015Inflammatory Bowel Diseases134 citations Open access
Semantic Scholar
A Novel Role for Interleukin-27 (IL-27) as Mediator of Intestinal Epithelial Barrier Protection Mediated via Differential Signal Transducer and Activator of Transcription (STAT) Protein Signaling and Induction of Antibacterial and Anti-inflammatory Proteins*
J. Diegelmann, T. Olszak, B. Göke, R. Blumberg +1 more
2011Journal of Biological Chemistry127 citations Open access
Semantic Scholar
Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk.
A. Fischer, D. Ellinghaus, Marcel Nutsua, Sylvia Hofmann +31 more
2015American Journal of Respiratory and Critical Care Medicine119 citations Open access
Semantic Scholar
Infliximab Does Not Affect Postoperative Complication Rates in Crohn's Patients Undergoing Abdominal Surgery
M. Kasparek, A. Bruckmeier, F. Beigel, M. Müller +5 more
2012Inflammatory Bowel Diseases88 citations Open access
Semantic Scholar
Formation of antinuclear and double‐strand DNA antibodies and frequency of lupus‐like syndrome in anti‐TNF‐&agr; antibody‐treated patients with inflammatory bowel disease
F. Beigel, F. Schnitzler, Rüdiger Paul Laubender, S. Pfennig +5 more
2011Inflammatory Bowel Diseases87 citations
Semantic Scholar
Intestinal neuroendocrine cells and goblet cells are mediators of IL-17A-amplified epithelial IL-17C production in human inflammatory bowel disease
M. Friedrich, J. Diegelmann, J. Schauber, C. Auernhammer +1 more
2014Mucosal Immunology78 citations Open access
Semantic Scholar
Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells
Jin Li, S. Jørgensen, S. M. Maggadóttir, M. Bakay +35 more
2015Nature Communications76 citations Open access
Semantic Scholar
Risk of malignancies in patients with inflammatory bowel disease treated with thiopurines or anti‐TNF alpha antibodies
F. Beigel, A. Steinborn, F. Schnitzler, C. Tillack +8 more
2014Pharmacoepidemiology and Drug Safety76 citations
Semantic Scholar
TNF-Alpha Blockers in Inflammatory Bowel Diseases: Practical Recommendations and a User’s Guide: An Update
M. Vulliemoz, S. Brand, P. Juillerat, C. Mottet +2 more
2020Digestion73 citations
Semantic Scholar
Colesevelam for the treatment of bile acid malabsorption-associated diarrhea in patients with Crohn's disease: a randomized, double-blind, placebo-controlled study.
F. Beigel, N. Teich, S. Howaldt, F. Lammert +6 more
2014Journal of Crohn's & Colitis73 citations Open access
Semantic Scholar
PTPN2 Gene Variants Are Associated with Susceptibility to Both Crohn's Disease and Ulcerative Colitis Supporting a Common Genetic Disease Background
J. Glas, Johanna Wagner, J. Seiderer, T. Olszak +12 more
2012PLoS ONE71 citations Open access
Semantic Scholar
Oncostatin M Mediates STAT3-Dependent Intestinal Epithelial Restitution via Increased Cell Proliferation, Decreased Apoptosis and Upregulation of SERPIN Family Members
F. Beigel, M. Friedrich, C. Probst, K. Sotlar +3 more
2014PLoS ONE67 citations Open access
Semantic Scholar
Emerging Treatment Options in Inflammatory Bowel Disease: Janus Kinases, Stem Cells, and More
B. Misselwitz, P. Juillerat, M. Sulz, B. Siegmund +1 more
2020Digestion65 citations Open access
Semantic Scholar
IRGM Variants and Susceptibility to Inflammatory Bowel Disease in the German Population
J. Glas, J. Seiderer, Stephanie K. Bues, Johannes Stallhofer +11 more
2013PLoS ONE65 citations Open access
Semantic Scholar
Analysis of IL12B Gene Variants in Inflammatory Bowel Disease
J. Glas, J. Seiderer, Johanna Wagner, T. Olszak +12 more
2012PLoS ONE63 citations Open access
Semantic Scholar
PTGER4 Expression-Modulating Polymorphisms in the 5p13.1 Region Predispose to Crohn's Disease and Affect NF-κB and XBP1 Binding Sites
J. Glas, J. Seiderer, D. Czamara, G. Pasciuto +11 more
2012PLoS ONE52 citations Open access
Semantic Scholar
The Role of Osteopontin (OPN/SPP1) Haplotypes in the Susceptibility to Crohn's Disease
J. Glas, J. Seiderer, Corinna Bayrle, Martin Wetzke +9 more
2011PLoS ONE48 citations Open access
Semantic Scholar
IL-36&ggr; Sustains a Proinflammatory Self-amplifying Loop with IL-17C in Anti-TNF–induced Psoriasiform Skin Lesions of Patients with Crohn's Disease
M. Friedrich, C. Tillack, A. Wollenberg, J. Schauber +1 more
2014Inflammatory Bowel Diseases47 citations
Semantic Scholar
Corrigendum: Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility
C. Anderson, G. Boucher, C. Lees, Andre Franke +109 more
2011Nature Genetics42 citations Open access
Semantic Scholar
The NOD2 Single Nucleotide Polymorphism rs72796353 (IVS4+10 A>C) Is a Predictor for Perianal Fistulas in Patients with Crohn's Disease in the Absence of Other NOD2 Mutations
F. Schnitzler, M. Friedrich, C. Wolf, Johannes Stallhofer +9 more
2015PLoS ONE40 citations Open access
Semantic Scholar
Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis
R. Brenig, O. Pop, E. Triantafyllou, Anne Geng +15 more
2019Life Science Alliance37 citations Open access
Semantic Scholar
Solid Organ Transplantation in Patients with Inflammatory Bowel Diseases (IBD): Analysis of Transplantation Outcome and IBD Activity in a Large Single Center Cohort
F. Schnitzler, M. Friedrich, Johannes Stallhofer, U. Schönermarck +15 more
2015PLoS ONE36 citations Open access
Semantic Scholar
Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease
J. Glas, J. Seiderer, Daniel Fischer, B. Tengler +12 more
2011Inflammatory Bowel Diseases36 citations Open access
Semantic Scholar
Rate and Predictors of Mucosal Healing in Patients with Inflammatory Bowel Disease Treated with Anti-TNF-Alpha Antibodies
F. Beigel, M. Deml, F. Schnitzler, S. Breiteneicher +3 more
2014PLoS ONE33 citations Open access
Semantic Scholar
Intestinal DMBT1 Expression Is Modulated by Crohn’s Disease-Associated IL23R Variants and by a DMBT1 Variant Which Influences Binding of the Transcription Factors CREB1 and ATF-2
J. Diegelmann, D. Czamara, E. Le Bras, E. Zimmermann +6 more
2013PLoS ONE30 citations Open access
Semantic Scholar
Perifosine-mediated Akt inhibition in neuroendocrine tumor cells: role of specific Akt isoforms.
Kathrin Zitzmann, G. Vlotides, S. Brand, H. Lahm +3 more
2012Endocrine-Related Cancer30 citations Open access
Semantic Scholar
The NOD2 p.Leu1007fsX1008 Mutation (rs2066847) Is a Stronger Predictor of the Clinical Course of Crohn's Disease than the FOXO3A Intron Variant rs12212067
F. Schnitzler, M. Friedrich, C. Wolf, Marianne Angelberger +9 more
2014PLoS ONE28 citations Open access
Semantic Scholar
The novel Raf inhibitor Raf265 decreases Bcl-2 levels and confers TRAIL-sensitivity to neuroendocrine tumour cells.
Kathrin Zitzmann, E. de Toni, J. von Rüden, S. Brand +3 more
2011Endocrine-Related Cancer28 citations Open access
Semantic Scholar
Contrast-enhanced ultrasound can guide the therapeutic strategy by improving the detection of colorectal liver metastases.
M. Sawatzki, U. Guller, S. Güsewell, D. Husarik +2 more
2020Journal of Hepatology27 citations
Semantic Scholar
Lifestyle factors associated with inflammatory bowel disease: data from the Swiss IBD cohort study
S. Lautenschlager, M. Barry, G. Rogler, L. Biedermann +181 more
2023BMC Gastroenterology23 citations Open access
Semantic Scholar
Immunochip analysis identifies association of the RAD50/IL13 region with human longevity
F. Flachsbart, D. Ellinghaus, Liljana Gentschew, Femke-Anouska Heinsen +19 more
2016Aging Cell22 citations Open access
Semantic Scholar
IL-17A Alone Weakly Affects the Transcriptome of Intestinal Epithelial Cells but Strongly Modulates the TNF-&agr;–induced Expression of Inflammatory Mediators and Inflammatory Bowel Disease Susceptibility Genes
M. Friedrich, J. Diegelmann, F. Beigel, S. Brand
2014Inflammatory Bowel Diseases22 citations
Semantic Scholar
Malignant melanoma during ustekinumab therapy of Crohn's disease.
L. Ehmann, Cornelia Tillack-Schreiber, S. Brand, A. Wollenberg
2012Inflammatory Bowel Diseases22 citations Open access
Semantic Scholar
Iron Status and Analysis of Efficacy and Safety of Ferric Carboxymaltose Treatment in Patients with Inflammatory Bowel Disease
F. Beigel, Beate Löhr, R. Laubender, C. Tillack +7 more
2011Digestion20 citations Open access
Semantic Scholar
Iron Deficiency in Inflammatory Bowel Disease Is Associated With Low Levels of Vitamin D Modulating Serum Hepcidin and Intestinal Ceruloplasmin Expression
J. Stallhofer, Lisa Veith, J. Diegelmann, P. Probst +7 more
2022Clinical and Translational Gastroenterology19 citations Open access
Semantic Scholar
Systemic and T cell‐associated responses to SARS‐CoV‐2 immunisation in gut inflammation (STAR SIGN study): effects of biologics on vaccination efficacy of the third dose of mRNA vaccines against SARS‐CoV‐2
Simon Woelfel, Joel Dütschler, Marius König, N. Graf +17 more
2022Alimentary Pharmacology and Therapeutics18 citations Open access
Semantic Scholar
Functional relevance of the cannabinoid receptor 2 - heme oxygenase pathway: a novel target for the attenuation of portal hypertension.
Christian J. Steib, Leonore Gmelin, S. Pfeiler, J. Schewe +3 more
2013Life Science18 citations
Semantic Scholar
Contrast-enhanced ultrasound (CEUS) has excellent diagnostic accuracy in differentiating focal liver lesions: results from a Swiss tertiary gastroenterological centre.
M. Sawatzki, C. Meyenberger, S. Brand, D. Semela
2019Swiss medical weekly17 citations Open access
Semantic Scholar
STAR SIGN study: Evaluation of COVID‐19 vaccine efficacy against the SARS‐CoV‐2 variants BQ.1.1 and XBB.1.5 in patients with inflammatory bowel disease
Simon Woelfel, Joel Dütschler, Marius König, A. Dulovic +22 more
2023Alimentary Pharmacology and Therapeutics14 citations
Semantic Scholar

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F. Beigel — researcher profile on SciRah
B. Göke×18
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J. Glas×15
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J. Glas — researcher profile on SciRah
J. Diegelmann×15
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M. Friedrich — researcher profile on SciRah

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T. Olszak — researcher profile on SciRah

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A. Franke — researcher profile on SciRah

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C. Tillack — researcher profile on SciRah

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R. Duerr — researcher profile on SciRah

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D. Ellinghaus — researcher profile on SciRah