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C. Peixoto · SciRah

Researcher profile · Semantic Scholar

C. Peixoto

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C. Peixoto — researcher profile on SciRah

h-index: 9
Works: 17
Citations: 466

Most-cited papers

Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fib
N. Desroy, Christopher Housseman, Xavier Bock, A. Joncour +26 more
2017Journal of Medicinal Chemistry125 citations Open access
Semantic Scholar
Discovery of diarylhydantoins as new selective androgen receptor modulators.
F. Nique, Séverine Hebbe, C. Peixoto, Denis Annoot +14 more
2012Journal of Medicinal Chemistry74 citations Open access
Semantic Scholar
Discovery of GLPG1972/S201086, a Potent, Selective, and Orally Bioavailable ADAMTS-5 Inhibitor for the Treatment of Osteoarthritis.
F. Brebion, R. Gosmini, P. Deprez, M. Varin +17 more
2021Journal of Medicinal Chemistry55 citations Open access
Semantic Scholar
Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors.
A. Joncour, N. Desroy, Christopher Housseman, Xavier Bock +30 more
2017Journal of Medicinal Chemistry50 citations Open access
Semantic Scholar
Synthesis of analogues of the O-beta-D-ribofuranosyl nucleoside moiety of liposidomycins. Part 1: contribution of the amino group and the uracil moiety upon the inhibition of MraY.
C. Dini, N. Drochon, S. Feteanu, J. C. Guillot +2 more
2001Bioorganic & Medicinal Chemistry Letters49 citations Open access
Semantic Scholar
Identification of a 4-(hydroxymethyl)diarylhydantoin as a selective androgen receptor modulator.
F. Nique, Séverine Hebbe, N. Triballeau, C. Peixoto +16 more
2012Journal of Medicinal Chemistry40 citations
Semantic Scholar
Discovery of Clinical Candidate GLPG3970: A Potent and Selective Dual SIK2/SIK3 Inhibitor for the Treatment of Autoimmune and Inflammatory Diseases
C. Peixoto, A. Joncour, Taouès Temal-Laib, Amynata Tirera +22 more
2024Journal of Medicinal Chemistry20 citations Open access
Semantic Scholar
Synthesis of isothiochroman 2,2-dioxide and 1,2-benzooxathiin 2,2-dioxide gyrase B inhibitors
C. Peixoto, P. Laurin, M. Klich, C. Dupuis-Hamelin +4 more
200018 citations
Semantic Scholar
Optimization of Selectivity and Pharmacokinetic Properties of Salt-Inducible Kinase Inhibitors that Led to the Discovery of Pan-SIK Inhibitor GLPG3312
Taouès Temal-Laib, C. Peixoto, Nicolas Desroy, E. D. de Lemos +21 more
2023Journal of Medicinal Chemistry16 citations Open access
Semantic Scholar
Synthesis of Analogues of the O-β-D-Ribofuranosyl Nucleoside Moiety of Liposidomycins. Part 1. Contribution of the Amino Group and the Uracil Moiety upon the Inhibition of MraY.
C. Dini, N. Drochon, S. Feteanu, J. C. Guillot +2 more
20018 citations
Semantic Scholar
Selective SIK2/SIK3 inhibition reprograms pro- and antiinflammatory pathways in myeloid cells, improving autoimmune disease outcomes
Steve De Vos, Nicolas Desroy, Susan Bellaire, Anna Pereira Fernandes +17 more
2026JCI Insight3 citations
Semantic Scholar
POS0442 GLPG4399: SELECTIVE SIK3 INHIBITION AS A NOVEL MODE OF ACTION FOR THE TREATMENT OF INFLAMMATORY ARTHRITIC DISEASES (PRECLINICAL)
S. Lavazais, A. Pereira-Fernandes, C. Delachaume, C. Jagerschmidt +8 more
2022Annals of the Rheumatic Diseases3 citations Open access
Semantic Scholar
Correction to Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2- a]pyridine Series of Autotaxin Inhibitors.
A. Joncour, N. Desroy, Christopher Housseman, Xavier Bock +30 more
2018Journal of Medicinal Chemistry3 citations Open access
Semantic Scholar
Structure activity relationship exploration of imidazo[1,2-a]pyridine series to reverse isoform selectivity and identify potent SIK1 selective inhibitors.
C. Peixoto, E. D. de Lemos, Laëtitia Cherel, Gregory Newsome +10 more
2025Bioorganic & Medicinal Chemistry Letters2 citations
Semantic Scholar
Structure of ar lbd with activator peptide and sarm inhibitor 2
F. Nique, S. Hebbe, C. Peixoto, D. Annoot +14 more
20120 citations
Semantic Scholar
Structure of ar lbd with activator peptide and sarm inhibitor 1
F. Nique, Séverine Hebbe, C. Peixoto, Denis Annoot +14 more
20120 citations
Semantic Scholar
Synthesis of Isothiochroman 2,2‐Dioxide and 1,2‐Benzooxathiin 2,2‐Dioxide Gyrase B Inhibitors.
C. Peixoto, P. Laurin, M. Klich, C. Dupuis-Hamelin +4 more
20000 citations
Semantic Scholar

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