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J. Trojanowski · SciRah

Researcher profile · Semantic Scholar

J. Trojanowski

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J. Trojanowski — researcher profile on SciRah

h-index: 235
Works: 1,371
Citations: 233K

Most-cited papers

Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK, GRB14, and KIAA0825 as novel risk loci for Alzheimer disease: the Alzheimer Disease Genetics Consortium
F. Rajabli, Penelope H. Benchek, G. Tosto, Nicholas A. Kushch +267 more
2023medRxiv1,124 citations Open access
Semantic Scholar
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration
Tara E. Tracy, Jesus Madero-Pérez, D. Swaney, Timothy S. Chang +26 more
2022Cell294 citations Open access
Semantic Scholar
Validation of Plasma Amyloid-β 42/40 for Detecting Alzheimer Disease Amyloid Plaques
Yan Li, S. Schindler, James G. Bollinger, Vitaliy Ovod +11 more
2021Neurology187 citations Open access
Semantic Scholar
Pathological combinations in neurodegenerative disease are heterogeneous and disease-associated
J. Robinson, Sharon X. Xie, Daniel R. Baer, Eunran Suh +11 more
2023Brain : a journal of neurology169 citations Open access
Semantic Scholar
Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue
S. Hardwick, Wengian Hu, Anoushka Joglekar, Li Fan +26 more
2022Nature Biotechnology118 citations Open access
Semantic Scholar
Increasing participant diversity in AD research: plans for digital screening, blood testing, and a community-engaged approach in the Alzheimer’s Disease Neuroimaging Initiative 4
M. Weiner, D. Veitch, Melanie J. Miller, P. Aisen +18 more
2022Alzheimer's & Dementia107 citations Open access
Semantic Scholar
Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α-synuclein
Shujing Zhang, Ruowei Zhu, Buyan Pan, Hong Xu +19 more
2023Nature Neuroscience106 citations Open access
Semantic Scholar
Tau deposition patterns are associated with functional connectivity in primary tauopathies
N. Franzmeier, M. Brendel, L. Beyer, Luna Slemann +56 more
2022Nature Communications105 citations Open access
Semantic Scholar
TRIM11 protects against tauopathies and is downregulated in Alzheimer’s disease
Zi-Yang Zhang, D. Harischandra, Ruifang Wang, Shivani Ghaisas +9 more
2023Science83 citations Open access
Semantic Scholar
Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study
Megan A. Iida, Kurt Farrell, Jamie M. Walker, T. Richardson +21 more
2021bioRxiv65 citations Open access
Semantic Scholar
Elevated plasma phosphorylated tau 181 in amyotrophic lateral sclerosis
K. Cousins, L. Shaw, S. Shellikeri, L. Dratch +12 more
2022medRxiv63 citations Open access
Semantic Scholar
Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction
Xiao-Pu Zhou, Yu Chen, Fanny C. F. Ip, Yuanbing Jiang +322 more
2023Communications Medicine60 citations Open access
Semantic Scholar
Autosomal dominant and sporadic late onset Alzheimer disease share a common in vivo pathophysiology.
J. Morris, M. Weiner, C. Xiong, Laurel A. Beckett +43 more
2022Brain : a journal of neurology58 citations Open access
Semantic Scholar
Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery
M. Hunter, Krista J. Spiller, Myrna A. Dominique, Hong Xu +7 more
2021Acta Neuropathologica Communications53 citations Open access
Semantic Scholar
Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease
Maiko T. Uemura, J. Robinson, K. Cousins, T. Tropea +14 more
2021Acta Neuropathologica51 citations Open access
Semantic Scholar
Traumatic brain injury and post-traumatic stress disorder are not associated with Alzheimer’s disease pathology measured with biomarkers
M. Weiner, D. Harvey, S. Landau, D. Veitch +11 more
2022Alzheimer's & Dementia47 citations Open access
Semantic Scholar
α-Synuclein aggregates amplified from patient-derived Lewy bodies recapitulate Lewy body diseases in mice
Norihito Uemura, Nicholas P. Marotta, J. Ara, Emily S. Meymand +6 more
2023Nature Communications46 citations Open access
Semantic Scholar
Genomewide Association Studies of LRRK2 Modifiers of Parkinson's Disease
Dong-Bing Lai, Babak Alipanahi, P. Fontanillas, Tae-Hwi Schwantes-An +57 more
2021Annals of Neurology42 citations Open access
Semantic Scholar
Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD mice
Argyro Thalia Delizannis, Annelies Nonneman, Wangchen Tsering, A. de Bondt +9 more
2021Acta Neuropathologica Communications39 citations Open access
Semantic Scholar
Association of CSF GAP-43 With the Rate of Cognitive Decline and Progression to Dementia in Amyloid-Positive Individuals
A. Öhrfelt, A. Benedet, N. Ashton, H. Kvartsberg +6 more
2022Neurology38 citations Open access
Semantic Scholar
Cognitive Profile and Markers of Alzheimer Disease–Type Pathology in Patients With Lewy Body Dementias
Erica Howard, D. Irwin, K. Rascovsky, Naomi Nevler +17 more
2021Neurology38 citations Open access
Semantic Scholar
Quantitative detection of α-Synuclein and Tau oligomers and other aggregates by digital single particle counting
Lara Blömeke, Marlene Pils, Victoria Kraemer-Schulien, Alexandra Dybala +18 more
2022npj Parkinson's Disease37 citations Open access
Semantic Scholar
Pathological drivers of neurodegeneration in suspected non-Alzheimer’s disease pathophysiology
L. Wisse, R. de Flores, L. Xie, S. Das +7 more
2021Alzheimer's Research & Therapy35 citations Open access
Semantic Scholar
Dopamine neurons exhibit emergent glutamatergic identity in Parkinson's disease.
Thomas Steinkellner, W. S. Conrad, I. Kovács, R. Rissman +7 more
2021Brain : a journal of neurology34 citations Open access
Semantic Scholar
Frontotemporal lobar degeneration proteinopathies have disparate microscopic patterns of white and grey matter pathology
Lucia A. A. Giannini, Claire S. Peterson, Daniel T. Ohm, Sharon X. Xie +10 more
2021Acta Neuropathologica Communications33 citations Open access
Semantic Scholar
Plasma phosphorylated tau181 predicts cognitive and functional decline
T. Tropea, T. Waligórska, Sharon X. Xie, I. Nasrallah +9 more
2022Annals of Clinical and Translational Neurology32 citations Open access
Semantic Scholar
Genetic prediction of impulse control disorders in Parkinson's disease
D. Weintraub, M. Posavi, P. Fontanillas, T. Tropea +6 more
2022Annals of Clinical and Translational Neurology32 citations Open access
Semantic Scholar
Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinson’s disease
Cheryl E. G. Leyns, A. Prigent, Brenna Beezhold, Lihang Yao +10 more
2022bioRxiv31 citations Open access
Semantic Scholar
Genome-wide association study and functional validation implicates JADE1 in tauopathy
Kurt Farrell, SoongHo Kim, Natalia Han, Megan A. Iida +85 more
2021bioRxiv31 citations Open access
Semantic Scholar
Plasma MIA, CRP, and albumin predict cognitive decline in Parkinson’s Disease
Junchao Shen, Noor Amari, Rebecca Zack, R. Skrinak +9 more
2022medRxiv30 citations Open access
Semantic Scholar
Inhibition of CK2 mitigates Alzheimer’s tau pathology by preventing NR2B synaptic mislocalization
Courtney A. Marshall, Jennifer D. McBride, Lakshmi Changolkar, Dawn M. Riddle +2 more
2022Acta Neuropathologica Communications27 citations Open access
Semantic Scholar
TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss
Tuancheng Feng, Lin Luan, Isabel Iscol Katz, Mohammed Ullah +4 more
2022Acta Neuropathologica Communications27 citations Open access
Semantic Scholar
Disease-, region- and cell type specific diversity of α-synuclein carboxy terminal truncations in synucleinopathies
Ethan W. Hass, Z. Sorrentino, Yuxing Xia, Grace M. Lloyd +3 more
2021Acta Neuropathologica Communications27 citations Open access
Semantic Scholar
TMEM106B modifies TDP-43 pathology in human ALS brain and cell-based models of TDP-43 proteinopathy
Fei Mao, J. Robinson, T. Unger, M. Posavi +10 more
2021bioRxiv26 citations Open access
Semantic Scholar
TREM2 risk variants are associated with atypical Alzheimer’s disease
Boram Kim, Eunran Suh, A. Nguyen, S. Prokop +12 more
2022Acta Neuropathologica25 citations Open access
Semantic Scholar
Interpretable deep learning of myelin histopathology in age-related cognitive impairment
Andrew T. McKenzie, G. Marx, Daniel G. Koenigsberg, M. Sawyer +59 more
2022bioRxiv25 citations Open access
Semantic Scholar
A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury
Xinyi Zhao, Wen Zeng, Hong Xu, Zihan Sun +18 more
2023Science Translational Medicine24 citations Open access
Semantic Scholar
Isoform-specific patterns of tau burden and neuronal degeneration in MAPT-associated frontotemporal lobar degeneration
Lucia A. A. Giannini, Daniel T. Ohm, A. Rozemuller, L. Dratch +8 more
2022Acta Neuropathologica24 citations Open access
Semantic Scholar
Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90
Laura M. Heath, J. Earls, A. Magis, S. Kornilov +195 more
2022Scientific Reports24 citations Open access
Semantic Scholar
Regional distribution and maturation of tau pathology among phenotypic variants of Alzheimer’s disease
Sanaz Arezoumandan, Sharon X. Xie, K. Cousins, D. Mechanic-Hamilton +12 more
2022Acta Neuropathologica24 citations Open access
Semantic Scholar
Signature laminar distributions of pathology in frontotemporal lobar degeneration
DT Ohm, K. Cousins, Sharon X. Xie, Claire S. Peterson +12 more
2022Acta Neuropathologica22 citations Open access
Semantic Scholar
CSF Biomarkers of Alzheimer Disease in Patients With Concomitant α-Synuclein Pathology
K. Cousins, Sanaz Arezoumandan, S. Shellikeri, Daniel T. Ohm +10 more
2022Neurology21 citations Open access
Semantic Scholar
ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer’s disease
Y.-A. Ko, J. Billheimer, N. Lyssenko, A. Kueider-Paisley +8 more
2022Alzheimer's Research & Therapy19 citations Open access
Semantic Scholar
Digital Histological Study of Neocortical Grey and White Matter Tau Burden Across Tauopathies.
D. Coughlin, A. Hiniker, Claire S. Peterson, Yongya Kim +13 more
2022Journal of Neuropathology and Experimental Neurology14 citations Open access
Semantic Scholar
Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy
Franziska Hopfner, Anja Tietz, Viktoria C. Ruf, O. Ross +68 more
2022Movement Disorders14 citations Open access
Semantic Scholar
Natural speech markers of Alzheimer’s disease co-pathology in Lewy body dementias
S. Shellikeri, Sunghye Cho, K. Cousins, M. Liberman +11 more
2022Parkinsonism & Related Disorders14 citations Open access
Semantic Scholar
Associations of phosphorylated tau pathology with whole-hemisphere ex-vivo morphometry in 7 tesla MRI
S. Sadaghiani, W. Trotman, Sydney A. Lim, E. Chung +31 more
2022Alzheimer's & Dementia13 citations Open access
Semantic Scholar
Non-Tremor Motor Dysfunction in Lewy Body Dementias is Associated with AD Biomarkers
Ian M Walker, Katheryn A. Q. Cousins, A. Siderowf, J. Duda +12 more
2022Parkinsonism & Related Disorders11 citations Open access
Semantic Scholar
Slow motor neurons resist pathological TDP-43 and mediate motor recovery in the rNLS8 model of amyotrophic lateral sclerosis
S. Hur, M. Hunter, Myrna A. Dominique, Madona Farag +5 more
2022Acta Neuropathologica Communications11 citations Open access
Semantic Scholar
PHASES OF VOLUME LOSS IN PATIENTS WITH KNOWN FRONTOTEMPORAL LOBAR DEGENERATION SPECTRUM PATHOLOGY
Sarah E. Burke, Jeffrey S. Phillips, Christopher A. Olm, Claire S. Peterson +7 more
2022Neurobiology of Aging11 citations Open access
Semantic Scholar

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