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Petr Špaček · SciRah

Researcher profile · Semantic Scholar

Petr Špaček

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Petr Špaček — researcher profile on SciRah

h-index: 19
Works: 94
Citations: 1,210

Most-cited papers

Recurrent Cenozoic volcanic activity in the Bohemian Massif (Czech Republic)
J. Ulrych, J. Dostal, J. Adamovič, E. Jelínek +3 more
2011164 citations
Semantic Scholar
Brunovistulian terrane (Bohemian Massif, Central Europe) from late Proterozoic to late Paleozoic: a review
J. Kalvoda, O. Bábek, O. Fatka, J. Leichmann +3 more
2008163 citations
Semantic Scholar
Alkaline and Carbonate-rich Melt Metasomatism and Melting of Subcontinental Lithospheric Mantle: Evidence from Mantle Xenoliths, NE Bavaria, Bohemian Massif
L. Ackerman, Petr Špaček, T. Magna, J. Ulrych +3 more
201380 citations
Semantic Scholar
Photocaged 5′ cap analogs for optical control of mRNA translation in cells
Nils Klöcker, Florian P. Weissenboeck, Melissa van Dülmen, Petr Špaček +2 more
2022Nature Chemistry69 citations Open access
Semantic Scholar
The Nysa-Morava Zone: an active tectonic domain with Late Cenozoic sedimentary grabens in the Western Carpathians’ foreland (NE Bohemian Massif)
Petr Špaček, O. Bábek, P. Štěpančíková, J. Švancara +2 more
2015International journal of earth sciences50 citations
Semantic Scholar
Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of the 6-oxopurine phosphoribosyltransferases and have antimalarial activity
D. Keough, Petr Špaček, D. Hocková, T. Tichý +9 more
2014Malaria Journal47 citations Open access
Semantic Scholar
Present-day seismicity of the south-eastern Elbe Fault System (NE Bohemian Massif)
Petr Špaček, Z. Sýkorová, J. Pazdírková, J. Švancara +1 more
200647 citations
Semantic Scholar
Inhibition of the Escherichia coli 6-oxopurine phosphoribosyltransferases by nucleoside phosphonates: potential for new antibacterial agents.
D. Keough, D. Hocková, D. Rejman, Petr Špaček +8 more
2013Journal of Medicinal Chemistry43 citations
Semantic Scholar
Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery
E. Dolezelova, D. Terán, O. Gahura, Z. Kotrbová +6 more
2018PLoS Neglected Tropical Diseases40 citations Open access
Semantic Scholar
First Crystal Structures of Mycobacterium tuberculosis 6-Oxopurine Phosphoribosyltransferase: Complexes with GMP and Pyrophosphate and with Acyclic Nucleoside Phosphonates Whose Prodrugs Have Antituberculosis Activity.
W. Eng, D. Hocková, Petr Špaček, Z. Janeba +5 more
2015Journal of Medicinal Chemistry39 citations Open access
Semantic Scholar
Garnet Breakdown, Symplectite Formation and Melting in Basanite-hosted Peridotite Xenoliths from Zinst (Bavaria, Bohemian Massif)
Petr Špaček, L. Ackerman, G. Habler, R. Abart +1 more
201337 citations Open access
Semantic Scholar
A benzophenone-based photocaging strategy for the N7 position of guanosine
L. Anhäuser, Nils Klöcker, F. Muttach, Florian Mäsing +3 more
2019Angewandte Chemie33 citations Open access
Semantic Scholar
Light‐Activated Translation of Different mRNAs in Cells via Wavelength‐Dependent Photouncaging
Amarnath Bollu, Nils Klöcker, Petr Špaček, Florian Peter Weissenböck +2 more
2022Angewandte Chemie28 citations Open access
Semantic Scholar
Flubendazole and mebendazole impair migration and epithelial to mesenchymal transition in oral cell lines.
V. Králová, V. Hanušová, K. Caltová, Petr Špaček +3 more
2018Chemico-Biological Interactions27 citations
Semantic Scholar
Geochemical and petrological constraints on mantle composition of the Ohře(Eger) rift, Bohemian Massif: peridotite xenoliths from the České Středohoří Volcanic complex and northern Bohemia
L. Ackerman, Gordon Medaris, Petr Špaček, J. Ulrych
2015International journal of earth sciences23 citations
Semantic Scholar
Synthesis and evaluation of symmetric acyclic nucleoside bisphosphonates as inhibitors of the Plasmodium falciparum, Plasmodium vivax and human 6-oxopurine phosphoribosyltransferases and the antimalarial activity of their prodrugs.
Petr Špaček, D. Keough, M. Chavchich, M. Dračínský +5 more
2017Bioorganic & Medicinal Chemistry22 citations Open access
Semantic Scholar
Fault slip versus slope deformations: Experience from paleoseismic trenches in the region with low slip-rate faults and strong Pleistocene periglacial mass wasting (Bohemian Massif)
Petr Špaček, J. Valenta, P. Tábořík, Vít Ambrož +2 more
201721 citations
Semantic Scholar
Rhenium–osmium isotopes in pervasively metasomatized mantle xenoliths from the Bohemian Massif and implications for the reliability of Os model ages
Yulia V. Kochergina, L. Ackerman, V. Erban, M. Matusiak-Małek +5 more
201620 citations
Semantic Scholar
Synthesis and Evaluation of Asymmetric Acyclic Nucleoside Bisphosphonates as Inhibitors of Plasmodium falciparum and Human Hypoxanthine-Guanine-(Xanthine) Phosphoribosyltransferase.
Petr Špaček, D. Keough, M. Chavchich, M. Dračínský +5 more
2017Journal of Medicinal Chemistry19 citations Open access
Semantic Scholar
MePMe-seq: Antibody-free simultaneous m6A and m5C mapping in mRNA by metabolic propargyl labeling and sequencing
Katja Hartstock, Anna Ovcharenko, Nadine A. Kueck, Petr Špaček +4 more
2022bioRxiv17 citations Open access
Semantic Scholar
Geochemistry and petrology of pyroxenite xenoliths from Cenozoic alkaline basalts, Bohemian Massif
L. Ackerman, Petr Špaček, Gordon Medaris, E. Hegner +2 more
201317 citations Open access
Semantic Scholar
Quantification of mRNA cap-modifications by means of LC-QqQ-MS
N. Muthmann, Petr Špaček, Dennis Reichert, Melissa van Dülmen +1 more
2021Methods16 citations Open access
Semantic Scholar
Elastic anisotropy and pore space geometry of schlieren granite: Direct 3-D measurements at high confining pressure combined with microfabric analysis
M. Staněk, Y. Géraud, Ondrej Lexa, Petr Špaček +2 more
201314 citations Open access
Semantic Scholar
An efficient oxa-Michael addition to diethyl vinylphosphonate under mild reaction conditions
O. Baszczyňski, P. Jansa, M. Dračínský, M. Kaiser +2 more
201214 citations
Semantic Scholar
Application of Formal Word-Level Analysis to Constrained Random Simulation
Hyondeuk Kim, HoonSang Jin, Kavita Ravi, Petr Špaček +3 more
2008International Conference on Computer Aided Verification13 citations Open access
Semantic Scholar
Origin and orientation of microporosity in eclogites of different microstructure studied by ultrasound and microfabric analysis
M. Machek, Petr Špaček, S. Ulrich, F. Heidelbach
200713 citations
Semantic Scholar
Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of 6-oxopurine phosphoribosyltransferases and have antimalarial activity.
D. Keough, Petr Špaček, D. Hocková, T. Tichý +9 more
2013Journal of Medicinal Chemistry12 citations Open access
Semantic Scholar
Pleistocene terraces of the Vltava River in the Budějovice basin (Southern Bohemian Massif): New insights into sedimentary history constrained by luminescence data
D. Homolová, J. Lomax, Petr Špaček, K. Decker
201210 citations
Semantic Scholar
Crystal Structures of Acyclic Nucleoside Phosphonates in Complex with Escherichia coli Hypoxanthine Phosphoribosyltransferase
W. Eng, D. Hocková, Petr Špaček, O. Baszczyňski +4 more
20169 citations
Semantic Scholar
Elastic anisotropy of core samples from the Taiwan Chelungpu Fault Drilling Project (TCDP): direct 3-D measurements and weak anisotropy approximations
L. Louis, C. David, Petr Špaček, T. Wong +2 more
20129 citations Open access
Semantic Scholar
Microseismic multiplets in the northeastern Bohemian Massif
Petr Špaček, Pavel Zacherle, Z. Sýkorová, J. Pazdírková
20119 citations
Semantic Scholar
Acyclic nucleoside phosphonates with adenine nucleobase inhibit Trypanosoma brucei adenine phosphoribosyltransferase in vitro
E. Dolezelova, Tomáš Klejch, Petr Špaček, M. Slapničková +3 more
2021Scientific Reports8 citations Open access
Semantic Scholar
A component-based meta-level architecture and prototypical implementation of a reflective component-based programming and modeling language
Petr Špaček, C. Dony, Chouki Tibermacine
2014International Symposium on Component-Based Software Engineering8 citations Open access
Semantic Scholar
An inheritance system for structural & behavioral reuse in component-based software programming
Petr Špaček, C. Dony, Chouki Tibermacine, L. Fabresse
2012International Conference on Generative Programming: Concepts and Experiences8 citations
Semantic Scholar
Microseismic activity of the Upper Morava basin and surroundings
Petr Špaček, Pavel Zacherle, Z. Sýkorová, J. Pazdírková +1 more
20087 citations
Semantic Scholar
Variation of deformation mechanisms within theprogressive-retrogressive mylonitization cycle of limestones:Brunovistulian sedimentary cover (the Variscan orogeny of theSoutheastern Bohemian Massif)
Petr Špaček, J. Kalvoda, E. Franců, R. Melichar
20016 citations
Semantic Scholar
Helicobacter pylori Xanthine-Guanine-Hypoxanthine Phosphoribosyltransferase-A Putative Target for Drug Discovery against Gastrointestinal Tract Infections.
D. Keough, Shun-Jie Wun, O. Baszczyňski, W. Eng +8 more
2021Journal of Medicinal Chemistry5 citations Open access
Semantic Scholar
Wringing out objects for programming and modeling component-based systems
Petr Špaček, C. Dony, Chouki Tibermacine, L. Fabresse
2013COOMPL@ECOOP4 citations Open access
Semantic Scholar
Efficient One‐Pot Synthesis of Polysubstituted 6‐[(1H‐1,2,3‐Triazol‐1‐yl)methyl]uracils Through the “Click” Protocol.
P. Jansa, Petr Špaček, I. Votruba, Petra Břehová +3 more
20114 citations
Semantic Scholar
Design and Implementation of a Reflective Component-Oriented Programming and Modeling Language
Petr Špaček
4 citations Open access
Semantic Scholar
Improving Cross-Border Seismic Research: The Central and Eastern Europe Earthquake Research Network (CE3RN)
W. Lenhardt, Damiano Pesaresi, M. Živčič, G. Costa +10 more
20213 citations
Semantic Scholar
The Role of Substitution in the Apex Position of the Bent-Core on Mesomorphic Properties of New Series of Liquid Crystalline Materials
Helena Skopalová, Petr Špaček, V. Kozmı́k, J. Svoboda +3 more
2020Crystals3 citations Open access
Semantic Scholar
Recent tectonic activity and orientations of the principalstresses in the Jeseníky region
J. Havíř, Petr Špaček
20043 citations
Semantic Scholar
Stratigraphic reconstruction of tectonically disturbed carbonate sequence along the western margin of the Brno batholith: a need of interdisciplinary approach
Petr Špaček, J. Kalvoda, J. Hladil, R. Melichar
20023 citations
Semantic Scholar
Geochemistry and Sr–Nd–Pb isotope characteristics of Miocene basalt–trachyte rock association in transitional zone between the Outer Western Carpathians and Bohemian Massif
L. Krmíček, J. Ulrych, Petra Šišková, Simona Krmíčková +2 more
20202 citations Open access
Semantic Scholar
Practical experiences with new types of highly modified asphalt binders
Petr Špaček, Zdeněk Hegr, J. Beneš
20172 citations Open access
Semantic Scholar
Usage of advanced functions of Dynamic Shear Rheometer for the selection of a suitable binder for asphalt mixtures
Ondrej Dasek, P. Hýzl, M. Varaus, Pavel Coufalík +2 more
20142 citations
Semantic Scholar
SLICE Seismic Lithospheric Investigation of Central Europe
Milan Brož, P. Hrubcová, F. Hubatka, O. Karousovâ +6 more
20052 citations
Semantic Scholar
The Nový Kostel earthquake swarm 2000 - Krasnet measurements
V. Nehybka, Radka Tilšarová, Petr Špaček
20032 citations
Semantic Scholar
Preliminary Results of Detailed Seismological Monitoring inHruby Jesenik Mts.
Z. Sýkorová, J. Švancara, J. Pazdírková, Petr Špaček +1 more
20022 citations
Semantic Scholar

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