Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Akira Nakajima · SciRah

Researcher profile · Semantic Scholar

Akira Nakajima

Share profile

Akira Nakajima — researcher profile on SciRah

h-index: 34
Works: 76
Citations: 3,821

Most-cited papers

IgA regulates the composition and metabolic function of gut microbiota by promoting symbiosis between bacteria
Akira Nakajima, A. Vogelzang, Mikako Maruya, Michio Miyajima +10 more
2018Journal of Experimental Medicine311 citations Open access
Semantic Scholar
Nobiletin, a Citrus Flavonoid, Improves Memory Impairment and Aβ Pathology in a Transgenic Mouse Model of Alzheimer's Disease
H. Onozuka, Akira Nakajima, K. Matsuzaki, R. Shin +8 more
2008Journal of Pharmacology and Experimental Therapeutics216 citations
Semantic Scholar
Potential Benefits of Nobiletin, A Citrus Flavonoid, against Alzheimer’s Disease and Parkinson’s Disease
Akira Nakajima, Y. Ohizumi
2019International Journal of Molecular Sciences200 citations Open access
Semantic Scholar
Nutritional Signaling via Free Fatty Acid Receptors
J. Miyamoto, Sae Hasegawa, Mayu Kasubuchi, A. Ichimura +2 more
2016International Journal of Molecular Sciences200 citations Open access
Semantic Scholar
Involvement of BDNF receptor TrkB in spatial memory formation.
M. Mizuno, Kiyofumi Yamada, Jue He, Akira Nakajima +1 more
2003Learning & memory (Cold Spring Harbor, N.Y.)196 citations Open access
Semantic Scholar
Role of Tumor Necrosis Factor-α in Methamphetamine-Induced Drug Dependence and Neurotoxicity
Akira Nakajima, Kiyofumi Yamada, T. Nagai, T. Uchiyama +16 more
2004Journal of Neuroscience160 citations Open access
Semantic Scholar
Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses
H. Negishi, H. Yanai, Akira Nakajima, Ryuji Koshiba +10 more
2012Nature Immunology148 citations
Semantic Scholar
Nobiletin, a citrus flavonoid, improves cognitive impairment and reduces soluble Aβ levels in a triple transgenic mouse model of Alzheimer's disease (3XTg-AD).
Akira Nakajima, Y. Aoyama, E. Shin, Yunsung Nam +7 more
2015Behavioural Brain Research135 citations
Semantic Scholar
Nobiletin, a citrus flavonoid that improves memory impairment, rescues bulbectomy-induced cholinergic neurodegeneration in mice.
Akira Nakajima, T. Yamakuni, Mitsuya Haraguchi, Naoki Omae +8 more
2007Journal of Pharmacological Sciences133 citations Open access
Semantic Scholar
The short chain fatty acid receptor GPR43 regulates inflammatory signals in adipose tissue M2-type macrophages
Akira Nakajima, A. Nakatani, Sae Hasegawa, Junichiro Irie +5 more
2017PLoS ONE130 citations Open access
Semantic Scholar
Nobiletin improves brain ischemia-induced learning and memory deficits through stimulation of CaMKII and CREB phosphorylation.
Yui Yamamoto, N. Shioda, F. Han, S. Moriguchi +7 more
2009Brain Research126 citations
Semantic Scholar
Neurobehavioral effects of tetrabromobisphenol A, a brominated flame retardant, in mice.
Akira Nakajima, D. Saigusa, Naomi Tetsu, T. Yamakuni +2 more
2009Toxicology Letters124 citations Open access
Semantic Scholar
The role of short-chain fatty acid on blood pressure regulation
J. Miyamoto, Mayu Kasubuchi, Akira Nakajima, Junichiro Irie +2 more
2016Current opinion in nephrology and hypertension114 citations
Semantic Scholar
Adult neurogenesis is functionally associated with AD-like neurodegeneration.
Qian Chen, Akira Nakajima, Se Hoon Choi, Xiaoli Xiong +2 more
2008Neurobiology of Disease102 citations Open access
Semantic Scholar
Role of tumor necrosis factor-alpha in methamphetamine-induced drug dependence and neurotoxicity.
Akira Nakajima, Kiyofumi Yamada, T. Nagai, T. Uchiyama +16 more
2004Journal of Neuroscience88 citations
Semantic Scholar
Structure, anti-tumor activity, and potential anti-tumor mechanism of a fungus polysaccharide from Fomes officinalis.
Shaojie Zhang, Ye-Ling Li, Zheng-Guo Li, Wenhui Liu +5 more
2022Carbohydrate Polymers75 citations
Semantic Scholar
4'-Demethylnobiletin, a bioactive metabolite of nobiletin enhancing PKA/ERK/CREB signaling, rescues learning impairment associated with NMDA receptor antagonism via stimulation of the ERK cascade.
Mawlavī ʿAbd al-Raḥīm, Akira Nakajima, D. Saigusa, Naomi Tetsu +7 more
2009Biochemistry71 citations
Semantic Scholar
Potent activity of nobiletin-rich Citrus reticulata peel extract to facilitate cAMP/PKA/ERK/CREB signaling associated with learning and memory in cultured hippocampal neurons: identification of the substances responsible for the pharmacological action
Ichiro Kawahata, Masaaki Yoshida, Wen-Xian Sun, Akira Nakajima +8 more
2013Journal of neural transmission65 citations
Semantic Scholar
Elevated cholecystokininergic tone constitutes an important molecular/neuronal mechanism for the expression of anxiety in the mouse.
Qian Chen, Akira Nakajima, C. Meacham, Ya-Ping Tang
2006Proceedings of the National Academy of Sciences of the United States of America64 citations Open access
Semantic Scholar
Nobiletin, a Citrus Flavonoid, Reverses Learning Impairment Associated with N-Methyl-D-aspartate Receptor Antagonism by Activation of Extracellular Signal-Regulated Kinase Signaling
Akira Nakajima, T. Yamakuni, K. Matsuzaki, N. Nakata +5 more
2007Journal of Pharmacology and Experimental Therapeutics61 citations
Semantic Scholar
Anti-dementia Activity of Nobiletin, a Citrus Flavonoid: A Review of Animal Studies
Akira Nakajima, Y. Ohizumi, Kiyofumi Yamada
2014Clinical Psychopharmacology and Neuroscience60 citations Open access
Semantic Scholar
An inducer for glial cell line-derived neurotrophic factor and tumor necrosis factor-alpha protects against methamphetamine-induced rewarding effects and sensitization.
M. Niwa, A. Nitta, Yuichiro Yamada, Akira Nakajima +6 more
2007Biological Psychiatry57 citations
Semantic Scholar
Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice
D. Ibi, T. Nagai, Akira Nakajima, H. Mizoguchi +13 more
2013Glia53 citations Open access
Semantic Scholar
Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes
A. Sobue, N. Ito, T. Nagai, Shan Wei +8 more
2018Glia51 citations
Semantic Scholar
Tumor Necrosis Factor-α and Its Inducer Inhibit Morphine-Induced Rewarding Effects and Sensitization
M. Niwa, A. Nitta, Yuichiro Yamada, Akira Nakajima +4 more
200751 citations
Semantic Scholar
Interleukin-6 protects PC12 cells from 4-hydroxynonenal-induced cytotoxicity by increasing intracellular glutathione levels.
Akira Nakajima, Kiyofumi Yamada, Li-Bo Zou, Yijin Yan +2 more
2002Free Radical Biology & Medicine48 citations
Semantic Scholar
Loss of presenilin function causes Alzheimer's disease‐like neurodegeneration in the mouse
Qian Chen, Akira Nakajima, Se Hoon Choi, Xiaoli Xiong +1 more
2008Journal of Neuroscience Research47 citations
Semantic Scholar
Post-Training Dephosphorylation of eEF-2 Promotes Protein Synthesis for Memory Consolidation
Heh-In Im, Akira Nakajima, Bo Gong, Xiaoli Xiong +4 more
2009PLoS ONE46 citations Open access
Semantic Scholar
Cell type-dependent proapoptotic role of Bcl2L12 revealed by a mutation concomitant with the disruption of the juxtaposed Irf3 gene
Akira Nakajima, K. Nishimura, Yukana Nakaima, Tomohiko Oh +3 more
2009Proceedings of the National Academy of Sciences of the United States of America46 citations Open access
Semantic Scholar
IRF3 regulates cardiac fibrosis but not hypertrophy in mice during angiotensin II‐induced hypertension
K. Tsushima, T. Osawa, H. Yanai, Akira Nakajima +6 more
2011The FASEB Journal44 citations
Semantic Scholar
A polysaccharide from Inula japonica showing in vivo antitumor activity by interacting with TLR-4, PD-1, and VEGF.
Xuelian Wang, Ye-Ling Li, Wenhui Liu, Yongye Shen +4 more
2023International Journal of Biological Macromolecules40 citations
Semantic Scholar
An evaluation of the genotoxicity and subchronic toxicity of the peel extract of Ponkan cultivar 'Ohta ponkan' (Citrus reticulata Blanco) that is rich in nobiletin and tangeretin with anti-dementia activity.
Akira Nakajima, K. Nemoto, Y. Ohizumi
2020Regulatory toxicology and pharmacology : RTP36 citations
Semantic Scholar
Learning and memory in two different reward tasks in a radial arm maze in rats.
Jue He, Kiyofumi Yamada, Akira Nakajima, H. Kamei +1 more
2002Behavioural Brain Research35 citations
Semantic Scholar
A novel cell-based assay for the evaluation of immune- and inflammatory-related gene expression as biomarkers for the risk assessment of drug-induced liver injury.
Shingo Oda, K. Matsuo, Akira Nakajima, T. Yokoi
2016Toxicology Letters34 citations
Semantic Scholar
Anti-Inflammatory and Insulin-Sensitizing Effects of Free Fatty Acid Receptors.
J. Miyamoto, Mayu Kasubuchi, Akira Nakajima, I. Kimura
2016Handbook of Experimental Pharmacology32 citations
Semantic Scholar
New aspects of IgA synthesis in the gut.
Keiichiro Suzuki, Akira Nakajima
2014International Immunology29 citations
Semantic Scholar
Toxicological role of an acyl glucuronide metabolite in diclofenac‐induced acute liver injury in mice
Shingo Oda, Yuji Shirai, S. Akai, Akira Nakajima +2 more
2017Journal of Applied Toxicology25 citations
Semantic Scholar
The potential role of Osteopontin in the maintenance of commensal bacteria homeostasis in the intestine
Koyu Ito, Akira Nakajima, Y. Fukushima, Keiichiro Suzuki +5 more
2017PLoS ONE25 citations Open access
Semantic Scholar
A Narrative Review of the Effects of Citrus Peels and Extracts on Human Brain Health and Metabolism
K. Matsuzaki, Akira Nakajima, Yuan-Qiang Guo, Y. Ohizumi
2022Nutrients24 citations Open access
Semantic Scholar
Regulation of cooperative function of the Il12b enhancer and promoter by the interferon regulatory factors 3 and 5.
Ryuji Koshiba, H. Yanai, A. Matsuda, Ayana Goto +5 more
2013Biochemical and Biophysical Research Communications - BBRC23 citations
Semantic Scholar
Discriminative-stimulus effects of methamphetamine and morphine in rats are attenuated by cAMP-related compounds.
Yijin Yan, A. Nitta, Tomoko Mizuno, Akira Nakajima +2 more
2006Behavioural Brain Research23 citations
Semantic Scholar
Phencyclidine-induced discriminative stimulus is mediated via phencyclidine binding sites on the N-methyl-D-aspartate receptor-ion channel complex , not via sigma 1 receptors
Akitomo Mori, Y. Noda, T. Mamiya, Y. Miyamoto +3 more
200123 citations
Semantic Scholar
Expression of the G72/G30 gene in transgenic mice induces behavioral changes
Lijun Cheng, E. Hattori, Akira Nakajima, N. S. Woehrle +7 more
2013Molecular Psychiatry21 citations Open access
Semantic Scholar
A novel diol-derivative of chalcone produced by bioconversion, 3-(2,3-dihydroxyphenyl)-1-phenylpropan-1-one, activates PKA/MEK/ERK signaling and antagonizes Abeta-inhibition of the cascade in cultured rat CNS neurons.
Mawlavī ʿAbd al-Raḥīm, Akira Nakajima, N. Misawa, K. Shindo +4 more
2008European Journal of Pharmacology20 citations
Semantic Scholar
Expression of NR2B in Cerebellar Granule Cells Specifically Facilitates Effect of Motor Training on Motor Learning
Jian-Wei Jiao, Akira Nakajima, W. Janssen, V. Bindokas +4 more
2008PLoS ONE19 citations Open access
Semantic Scholar
Anatomical substrates for the discriminative stimulus effects of methamphetamine in rats
Akira Nakajima, Kiyofumi Yamada, Jue He, Nan Zeng +2 more
2004Journal of Neurochemistry18 citations
Semantic Scholar
Anthocyanin-rich blackcurrant extract improves long-term memory impairment and emotional abnormality in senescence-accelerated mice.
Minori Shimada, Hayato Maeda, Naoki Nanashima, Kiyofumi Yamada +1 more
2022Journal of food biochemistry16 citations Open access
Semantic Scholar
Innate immune activation of astrocytes impairs neurodevelopment via upregulation of follistatin-like 1 and interferon-induced transmembrane protein 3
Shinnosuke Yamada, N. Itoh, T. Nagai, T. Nakai +4 more
2018Journal of Neuroinflammation16 citations Open access
Semantic Scholar
Matrix metalloproteinase-3 is a possible mediator of neurodevelopmental impairment due to polyI:C-induced innate immune activation of astrocytes.
Shinnosuke Yamada, T. Nagai, T. Nakai, D. Ibi +2 more
2014Brain, behavior, and immunity16 citations Open access
Semantic Scholar
SLC10A4 is a protease-activated transporter that transports bile acids.
Takuya Abe, Yoshitomi Kanemitu, Masateru Nakasone, Ichiro Kawahata +6 more
2013Journal of Biochemistry (Tokyo)16 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

Kiyofumi Yamada×14
Invite
Kiyofumi Yamada — researcher profile on SciRah
T. Nabeshima×13
Invite
T. Nabeshima — researcher profile on SciRah
Y. Ohizumi×12
Invite
Y. Ohizumi — researcher profile on SciRah
T. Yamakuni×9
Invite
T. Yamakuni — researcher profile on SciRah

×7

Invite

T. Nagai — researcher profile on SciRah

Invite

A. Yokosuka — researcher profile on SciRah

Invite

Y. Mimaki — researcher profile on SciRah

Invite

A. Nitta — researcher profile on SciRah

Ya-Ping Tang×6

Invite

Ya-Ping Tang — researcher profile on SciRah

Invite

Jue He — researcher profile on SciRah

Kuniaki Saito×5

Invite

Kuniaki Saito — researcher profile on SciRah

K. Matsuzaki×4

Invite

K. Matsuzaki — researcher profile on SciRah