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Till Adhikary · SciRah

Researcher profile · Semantic Scholar

Till Adhikary

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Till Adhikary — researcher profile on SciRah

h-index: 21
Works: 37
Citations: 2,432

Most-cited papers

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes
M. Luu, S. Pautz, Vanessa Kohl, Rajeev Singh +15 more
2019Nature Communications445 citations Open access
Semantic Scholar
Regulation of the effector function of CD8+ T cells by gut microbiota-derived metabolite butyrate
M. Luu, K. Weigand, Fatana Wedi, Carina Breidenbend +4 more
2018Scientific Reports314 citations Open access
Semantic Scholar
The Unique Molecular and Cellular Microenvironment of Ovarian Cancer
Thomas Worzfeld, Elke Pogge von Strandmann, M. Huber, Till Adhikary +3 more
2017Frontiers in Oncology253 citations Open access
Semantic Scholar
Lactate induces metabolic and epigenetic reprogramming of pro‐inflammatory Th17 cells
Aleksandra Lopez Krol, H. Nehring, Felix F. Krause, Anne Wempe +11 more
2022EMBO Reports166 citations Open access
Semantic Scholar
A transcriptome-based global map of signaling pathways in the ovarian cancer microenvironment associated with clinical outcome
S. Reinartz, F. Finkernagel, Till Adhikary, Verena Rohnalter +9 more
2016Genome Biology101 citations Open access
Semantic Scholar
Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment
Tim Schumann, Till Adhikary, A. Wortmann, F. Finkernagel +13 more
2015OncoTarget94 citations Open access
Semantic Scholar
Sequential Activation of NFAT and c-Myc Transcription Factors Mediates the TGF-β Switch from a Suppressor to a Promoter of Cancer Cell Proliferation*
Garima Singh, Shiv K. Singh, A. König, K. Reutlinger +6 more
2010Journal of Biological Chemistry93 citations Open access
Semantic Scholar
15-Hydroxyeicosatetraenoic Acid Is a Preferential Peroxisome Proliferator-Activated Receptor β/δ Agonist
Simone Naruhn, W. Meissner, Till Adhikary, Kerstin Kaddatz +4 more
2010Molecular Pharmacology87 citations
Semantic Scholar
The transcriptional signature of human ovarian carcinoma macrophages is associated with extracellular matrix reorganization
F. Finkernagel, S. Reinartz, Sonja Lieber, Till Adhikary +9 more
2016OncoTarget86 citations Open access
Semantic Scholar
The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state
Till Adhikary, A. Wortmann, Tim Schumann, F. Finkernagel +10 more
2015Nucleic Acids Research79 citations Open access
Semantic Scholar
A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory secretory phenotype
Verena Rohnalter, K. Roth, F. Finkernagel, Till Adhikary +5 more
2015OncoTarget78 citations Open access
Semantic Scholar
Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion
Till Adhikary, Dominique T. Brandt, Kerstin Kaddatz, Josefine Stockert +14 more
2012Oncogene75 citations Open access
Semantic Scholar
Genomewide Analyses Define Different Modes of Transcriptional Regulation by Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ)
Till Adhikary, Kerstin Kaddatz, F. Finkernagel, Anne Schönbauer +6 more
2011PLoS ONE72 citations Open access
Semantic Scholar
Transcriptional Profiling Identifies Functional Interactions of TGFβ and PPARβ/δ Signaling
Kerstin Kaddatz, Till Adhikary, F. Finkernagel, W. Meissner +2 more
2010Journal of Biological Chemistry67 citations Open access
Semantic Scholar
Interferon signaling in ascites-associated macrophages is linked to a favorable clinical outcome in a subgroup of ovarian carcinoma patients
Till Adhikary, A. Wortmann, F. Finkernagel, Sonja Lieber +6 more
2017BMC Genomics58 citations Open access
Semantic Scholar
Proteotranscriptomics Reveal Signaling Networks in the Ovarian Cancer Microenvironment
Thomas Worzfeld, F. Finkernagel, S. Reinartz, Anne Konzer +7 more
2017Molecular & Cellular Proteomics55 citations Open access
Semantic Scholar
Lysophosphatidylcholines activate PPARδ and protect human skeletal muscle cells from lipotoxicity.
C. Klingler, Xin-Jie Zhao, Till Adhikary, Jia Li +5 more
2016Biochimica et Biophysica Acta49 citations
Semantic Scholar
Reverse crosstalk of TGFβ and PPARβ/δ signaling identified by transcriptional profiling
Josefine Stockert, Till Adhikary, Kerstin Kaddatz, F. Finkernagel +3 more
2010Nucleic Acids Res.49 citations Open access
Semantic Scholar
(Z)-2-(2-bromophenyl)-3-{[4-(1-methyl-piperazine)amino]phenyl}acrylonitrile (DG172): an orally bioavailable PPARβ/δ-selective ligand with inverse agonistic properties.
Sonja Lieber, F. Scheer, W. Meissner, Simone Naruhn +4 more
2012Journal of Medicinal Chemistry45 citations Open access
Semantic Scholar
High-Affinity Peroxisome Proliferator-Activated Receptor β/δ-Specific Ligands with Pure Antagonistic or Inverse Agonistic Properties
Simone Naruhn, Philipp M. Toth, Till Adhikary, Kerstin Kaddatz +6 more
2011Molecular Pharmacology42 citations
Semantic Scholar
Epigenome-wide DNA methylation profiling in Progressive Supranuclear Palsy reveals major changes at DLX1
A. Weber, S. Schwarz, J. Tost, D. Trümbach +15 more
2018Nature Communications29 citations Open access
Semantic Scholar
KLF4-mediated upregulation of the NKG2D ligand MICA in acute myeloid leukemia: a novel therapeutic target identified by enChIP
Reem Alkhayer, Viviane Ponath, M. Frech, Till Adhikary +3 more
2023Cell Communication and Signaling21 citations Open access
Semantic Scholar
PPARβ/δ recruits NCOR and regulates transcription reinitiation of ANGPTL4
N. Legrand, C. Bretscher, Svenja Zielke, Bernhard Wilke +4 more
2019bioRxiv17 citations Open access
Semantic Scholar
Chromatin Binding of c-REL and p65 Is Not Limiting for Macrophage IL12B Transcription During Immediate Suppression by Ovarian Carcinoma Ascites
Annika Unger, F. Finkernagel, Nathalie Hoffmann, Felix Neuhaus +9 more
2018Frontiers in Immunology12 citations Open access
Semantic Scholar
Activation of Cilia-Independent Hedgehog/GLI1 Signaling as a Novel Concept for Neuroblastoma Therapy
Anke Koeniger, A. Brichkina, Iris Nee, Lukas Dempwolff +8 more
2021Cancers11 citations Open access
Semantic Scholar
Haptoglobin buffers lipopolysaccharides to delay activation of NFκB
Laura Zein, Josina Grossmann, Helena Swoboda, Christina Borgel +8 more
2024Frontiers in Immunology8 citations Open access
Semantic Scholar
Design and Synthesis of Highly Active Peroxisome Proliferator‐Activated Receptor (PPAR) β/δ Inverse Agonists with Prolonged Cellular Activity
Philipp M. Toth, Sonja Lieber, F. Scheer, Tim Schumann +6 more
2016ChemMedChem8 citations
Semantic Scholar
In vivo studies of PPAR-chromatin interactions: chromatin immunoprecipitation for single-locus and genomewide analyses.
Till Adhikary, Rolf Müller
2013Methods in molecular biology6 citations
Semantic Scholar
The mammalian Hedgehog pathway is modulated by ANP32 proteins.
A. Hupfer, A. Brichkina, Till Adhikary, M. Lauth
2021Biochemical and Biophysical Research Communications - BBRC5 citations
Semantic Scholar
Tumor-suppressive disruption of cancer subtype-associated super enhancer circuits by small molecule treatment
Anke Koeniger, Pierfrancesco Polo, A. Brichkina, F. Finkernagel +8 more
2023NAR Cancer4 citations Open access
Semantic Scholar
ER-phagy mediates the anti-tumoral synergism between HDAC inhibition and chemotherapy
Felix J. Gössl, Pierfrancesco Polo, Frederik Helmprobst, André Menzenbach +4 more
2025Cell Communication and Signaling3 citations Open access
Semantic Scholar
Pi-seq—A customizable multichannel syringe pump for microfluidics
Tim L. Czech, Philipp P. Nelson, C. Thölken, Patrick Meyer +3 more
2024HardwareX3 citations Open access
Semantic Scholar
Small-Molecule-Mediated Depletion of the Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1B (DYRK1B) Protein Scaffold
Miriam S. Ems, Mattias F. Lindberg, Till Adhikary, Laurent Meijer +1 more
2026ACS Pharmacology & Translational Science0 citations Open access
Semantic Scholar
Haptoglobin buffers lipopolysaccharides to safeguard against aberrant NFκB activation
Laura Zein, Josina Grossmann, Helena Swoboda, Christina Borgel +8 more
2023bioRxiv0 citations Open access
Semantic Scholar
Cover Picture: Design and Synthesis of Highly Active Peroxisome Proliferator-Activated Receptor (PPAR) β/δ Inverse Agonists with Prolonged Cellular Activity (ChemMedChem 5/2016)
Philipp M. Toth, Sonja Lieber, F. Scheer, Tim Schumann +6 more
20160 citations Open access
Semantic Scholar
The transcriptional PPAR (cid:2) / (cid:3) network in human macrophages deﬁnes a unique agonist-induced activation state
Till Adhikary, A. Wortmann, Tim Schumann, F. Finkernagel +10 more
20150 citations
Semantic Scholar
Sequential Activation of NFAT and c-Myc Transcription Factors Mediates the TGF- Switch from a Suppressor to a
Garima Singh, Shiv K. Singh, K. Reutlinger, M. Nye +5 more
20100 citations
Semantic Scholar

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