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P. Pagano · SciRah

Researcher profile · Semantic Scholar

P. Pagano

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P. Pagano — researcher profile on SciRah

h-index: 53
Works: 157
Citations: 13K

Most-cited papers

Platelet-derived HMGB1 is a critical mediator of thrombosis.
Sebastian Vogel, R. Bodenstein, Qiwei Chen, S. Feil +21 more
2015Journal of Clinical Investigation326 citations Open access
Semantic Scholar
Oxidases and Peroxidases in Cardiovascular and Lung Disease: New Concepts in Reactive Oxygen Species Signaling
I. Al Ghouleh, N. Khoo, U. Knaus, K. Griendling +12 more
2011Free Radical Biology & Medicine248 citations Open access
Semantic Scholar
Hydrogen Peroxide as a Paracrine Vascular Mediator: Regulation and Signaling Leading to Dysfunction
N. Ardanaz, P. Pagano
2006Experimental biology and medicine241 citations
Semantic Scholar
Thrombospondin-1 supports blood pressure by limiting eNOS activation and endothelial-dependent vasorelaxation.
E. Bauer, Yan Qin, Thomas W. Miller, Russell W. Bandle +6 more
2010Cardiovascular Research154 citations Open access
Semantic Scholar
Role of Inflammation in the Development of Renal Damage and Dysfunction in Angiotensin II–Induced Hypertension
Tang-Dong Liao, Xiao-Ping Yang, Yun-He Liu, E. Shesely +4 more
2008HYPERTENSION151 citations Open access
Semantic Scholar
Adventitial fibroblast reactive oxygen species as autacrine and paracrine mediators of remodeling: bellwether for vascular disease?
M. Haurani, P. Pagano
2007Cardiovascular Research141 citations Open access
Semantic Scholar
NADPH oxidases: key modulators in aging and age-related cardiovascular diseases?
S. Sahoo, Daniel N. Meijles, P. Pagano
2016Clinical science137 citations Open access
Semantic Scholar
Nox2 B-loop Peptide, Nox2ds, Specifically Inhibits Nox2 Oxidase
G. Csányi, Eugenia Cifuentes-Pagano, I. Al Ghouleh, Daniel J. Ranayhossaini +5 more
2011Free Radical Biology & Medicine135 citations Open access
Semantic Scholar
Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging
A. Robinson, Matthew J. Yousefzadeh, Tania A. Rozgaja, Jin Wang +38 more
2018Redox Biology129 citations Open access
Semantic Scholar
Arsenic-stimulated liver sinusoidal capillarization in mice requires NADPH oxidase-generated superoxide.
A. Straub, K. A. Clark, M. Ross, Ashwin Chandra +5 more
2008Journal of Clinical Investigation119 citations Open access
Semantic Scholar
Thrombospondin-1 Regulates Blood Flow via CD47 Receptor-Mediated Activation of NADPH Oxidase 1
G. Csányi, Mingyi Yao, Andres I. Rodriguez, I. Ghouleh +6 more
2012Arteriosclerosis, Thrombosis and Vascular Biology113 citations Open access
Semantic Scholar
Identification and characterization of VPO1, a new animal heme-containing peroxidase.
G. Cheng, J. C. Salerno, Ze-Hong Cao, P. Pagano +1 more
2008Free Radical Biology & Medicine107 citations Open access
Semantic Scholar
NOX and Inflammation in the Vascular Adventitia
G. Csányi, W. Taylor, P. Pagano
2009Free Radical Biology & Medicine104 citations Open access
Semantic Scholar
NADPH oxidase inhibitors: a decade of discovery from Nox2ds to HTS
Eugenia Cifuentes-Pagano, G. Csányi, P. Pagano
2012Cellular and Molecular Life Sciences98 citations Open access
Semantic Scholar
The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1
Daniel N. Meijles, S. Sahoo, I. Al Ghouleh, J. Amaral +11 more
2017Science Signaling95 citations Open access
Semantic Scholar
MEF2B - Nox1 Signaling is Critical for Stretch-Induced Phenotypic Modulation of Vascular Smooth Muscle Cells
Andres I. Rodriguez, G. Csányi, Daniel J. Ranayhossaini, Douglas M Feck +4 more
2014Arteriosclerosis, Thrombosis and Vascular Biology90 citations Open access
Semantic Scholar
Thrombospondin-1 and CD47 Regulation of Cardiac, Pulmonary and Vascular Responses in Health and Disease
N. Rogers, Maryam Sharifi-Sanjani, G. Csányi, P. Pagano +1 more
2014Matrix Biology89 citations Open access
Semantic Scholar
The Quest for Selective Nox Inhibitors and Therapeutics: Challenges, Triumphs and Pitfalls
Eugenia Cifuentes-Pagano, Daniel N. Meijles, P. Pagano
2014Antioxidants and Redox Signaling85 citations Open access
Semantic Scholar
Thrombospondin-1 activation of signal-regulatory protein-α stimulates reactive oxygen species production and promotes renal ischemia reperfusion injury.
Mingyi Yao, N. Rogers, G. Csányi, Andres I. Rodriguez +7 more
2014Journal of the American Society of Nephrology80 citations Open access
Semantic Scholar
The Role of NADPH Oxidases in the Etiology of Obesity and Metabolic Syndrome: Contribution of Individual Isoforms and Cell Biology
E. DeVallance, Yao Li, M. Jurczak, Eugenia Cifuentes-Pagano +1 more
2019Antioxidants and Redox Signaling79 citations Open access
Semantic Scholar
Aquaporin 1, Nox1, and Ask1 mediate oxidant-induced smooth muscle cell hypertrophy.
I. Al Ghouleh, Giovanna Frazziano, Andres I. Rodriguez, G. Csányi +8 more
2013Cardiovascular Research75 citations Open access
Semantic Scholar
Microvascular NADPH oxidase in health and disease
Yao Li, P. Pagano
2017Free Radical Biology & Medicine74 citations Open access
Semantic Scholar
Recent Advances in Hypertension: Nox and Inflammation in the Vascular Adventitia
Daniel N. Meijles, P. Pagano
2015HYPERTENSION73 citations Open access
Semantic Scholar
NADPH oxidase-derived ROS and the regulation of pulmonary vessel tone.
Giovanna Frazziano, H. Champion, P. Pagano
2012American Journal of Physiology. Heart and Circulatory Physiology68 citations Open access
Semantic Scholar
Selective Recapitulation of Conserved and Nonconserved Regions of Putative NOXA1 Protein Activation Domain Confers Isoform-specific Inhibition of Nox1 Oxidase and Attenuation of Endothelial Cell Migration*
Daniel J. Ranayhossaini, Andres I. Rodriguez, S. Sahoo, Beibei Chen +6 more
2013Journal of Biological Chemistry67 citations Open access
Semantic Scholar
Enhanced myogenic response in the afferent arteriole of spontaneously hypertensive rats.
Yi-Lin Ren, M. D’Ambrosio, Ruisheng Liu, P. Pagano +2 more
2010American Journal of Physiology. Heart and Circulatory Physiology65 citations Open access
Semantic Scholar
HO-1 and CO decrease platelet-derived growth factor-induced vascular smooth muscle cell migration via inhibition of Nox1
Andres I. Rodriguez, A. Gangopadhyay, E. Kelley, P. Pagano +2 more
2009Arteriosclerosis, Thrombosis and Vascular Biology57 citations Open access
Semantic Scholar
Nox Inhibitors & Therapies: Rational Design of Peptidic and Small Molecule Inhibitors
M. E. Cifuentes-pagano, Daniel N. Meijles, P. Pagano
2015Current pharmaceutical design55 citations Open access
Semantic Scholar
MEF2C-MYOCD and Leiomodin1 Suppression by miRNA-214 Promotes Smooth Muscle Cell Phenotype Switching in Pulmonary Arterial Hypertension
S. Sahoo, Daniel N. Meijles, I. Al Ghouleh, Manuj Tandon +5 more
2016PLoS ONE53 citations Open access
Semantic Scholar
Endothelial Nox1 oxidase assembly in human pulmonary arterial hypertension; driver of Gremlin1-mediated proliferation
I. Al Ghouleh, S. Sahoo, Daniel N. Meijles, J. Amaral +6 more
2017Clinical science51 citations Open access
Semantic Scholar
Depolarization of the macula densa induces superoxide production via NAD(P)H oxidase.
Ruisheng Liu, J. Garvin, Yi-Lin Ren, P. Pagano +1 more
2007AJP - Renal Physiology49 citations
Semantic Scholar
NADPH oxidase 2 activity in Parkinson’s disease
Matthew T. Keeney, Eric K. Hoffman, K. Farmer, Christopher R Bodle +12 more
2022Neurobiology of Disease47 citations Open access
Semantic Scholar
Vascular TSP1-CD47 signaling promotes sickle cell-associated arterial vasculopathy and pulmonary hypertension in mice.
Enrico M. Novelli, L. Little-Ihrig, Heather E. Knupp, N. Rogers +11 more
2019American Journal of Physiology - Lung cellular and Molecular Physiology44 citations Open access
Semantic Scholar
CD47 Promotes Age-Associated Deterioration in Angiogenesis, Blood Flow and Glucose Homeostasis
K. Ghimire, Yao Li, Takuto Chiba, S. Julovi +8 more
2020Cells42 citations Open access
Semantic Scholar
Nox1/Ref-1-mediated activation of CREB promotes Gremlin1-driven endothelial cell proliferation and migration
D. D. de Jesus, E. DeVallance, Yao Li, M. Falabella +5 more
2019Redox Biology42 citations Open access
Semantic Scholar
The adventitia: the outs and ins of vascular disease.
P. Pagano, D. Gutterman
2007Cardiovascular Research42 citations Open access
Semantic Scholar
Hepatocyte-Specific Ablation or Whole-Body Inhibition of Xanthine Oxidoreductase in Mice Corrects Obesity-Induced Systemic Hyperuricemia Without Improving Metabolic Abnormalities
Daniel Harmon, W. Mandler, I. Sipula, N. Dedousis +13 more
2019Diabetes38 citations Open access
Semantic Scholar
Mitochondria in Cardiovascular Physiology and Disease Nox-derived ROS are acutely activated in pressure overload pulmonary hypertension : indications for a seminal role for mitochondrial Nox 4
Giovanna Frazziano, I. Al Ghouleh, J. Baust, S. Shiva +2 more
201336 citations
Semantic Scholar
Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitors
Eugenia Cifuentes-Pagano, Jaideep Saha, G. Csányi, I. Ghouleh +5 more
2013MedChemComm34 citations Open access
Semantic Scholar
Forestalling age-impaired angiogenesis and blood flow by targeting NOX: Interplay of NOX1, IL-6, and SASP in propagating cell senescence
Yao Li, D. Kračun, C. Dustin, M. El Massry +10 more
2021Proceedings of the National Academy of Sciences of the United States of America30 citations Open access
Semantic Scholar
CD47 and Nox1 Mediate Dynamic Fluid-Phase Macropinocytosis of Native LDL
G. Csányi, Douglas M Feck, Pushpankur Ghoshal, Bhupesh Singla +10 more
2017Antioxidants and Redox Signaling30 citations Open access
Semantic Scholar
Adventitia-Derived Hydrogen Peroxide Impairs Relaxation of the Rat Carotid Artery via Smooth Muscle Cell p38 Mitogen-Activated Protein Kinase
T. Cascino, G. Csányi, I. Al Ghouleh, A. Montezano +3 more
2011Antioxidants and Redox Signaling30 citations Open access
Semantic Scholar
Binding of EBP50 to Nox organizing subunit p47phox is pivotal to cellular reactive species generation and altered vascular phenotype
I. Al Ghouleh, Daniel N. Meijles, Stephanie M. Mutchler, Qiangmin Zhang +10 more
2016Proceedings of the National Academy of Sciences of the United States of America29 citations Open access
Semantic Scholar
Notch2 Suppression Mimicking Changes in Human Pulmonary Hypertension Modulates Notch1 and Promotes Endothelial Cell Proliferation.
S. Sahoo, Yao Li, D. D. de Jesus, John Charles Sembrat Ii +5 more
2021American Journal of Physiology. Heart and Circulatory Physiology27 citations Open access
Semantic Scholar
A novel combinatorial technique for simultaneous quantification of oxygen radicals and aggregation reveals unexpected redox patterns in the activation of platelets by different physiopathological stimuli
D. Vara, Eugenia Cifuentes-Pagano, P. Pagano, G. Pula
2019Haematologica27 citations Open access
Semantic Scholar
Distinct hydrogen peroxide-induced constriction in multiple mouse arteries: potential influence of vascular polarization.
N. Ardanaz, W. Beierwaltes, P. Pagano
2008Pharmacological Reports27 citations
Semantic Scholar
Endothelial-Derived miR-17∼92 Promotes Angiogenesis to Protect against Renal Ischemia-Reperfusion Injury.
Takuto Chiba, D. Cerqueira, Yao Li, Andrew J. Bodnar +10 more
2021Journal of the American Society of Nephrology26 citations Open access
Semantic Scholar
Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation
Shuang Yuan, Scott A. Hahn, Megan P. Miller, S. Sanker +15 more
2021bioRxiv25 citations Open access
Semantic Scholar
DELETION OF iNOS PROVIDES CARDIOPROTECTION IN MICE WITH 2-KIDNEY, 1-CLIP HYPERTENSION
Ying Sun, O. Carretero, Jiang Xu, N. Rhaleb +3 more
2008HYPERTENSION24 citations Open access
Semantic Scholar
Redox-modulating agents target NOX2-dependent IKKε oncogenic kinase expression and proliferation in human breast cancer cell lines
Espérance Mukawera, Stéfany Chartier, V. Williams, P. Pagano +2 more
2015Redox Biology20 citations Open access
Semantic Scholar

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Eugenia Cifuentes-Pagano — researcher profile on SciRah
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I. Al Ghouleh×10
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E. Kelley — researcher profile on SciRah

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A. Straub — researcher profile on SciRah