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T. Ikeda · SciRah

Researcher profile · Semantic Scholar

T. Ikeda

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T. Ikeda — researcher profile on SciRah

h-index: 21
Works: 70
Citations: 2,466

Most-cited papers

A multicenter, prospective validation of disseminated intravascular coagulation diagnostic criteria for critically ill patients: Comparing current criteria*
S. Gando, T. Iba, Y. Eguchi, Y. Ohtomo +12 more
2006Critical Care Medicine588 citations
Semantic Scholar
Natural history of disseminated intravascular coagulation diagnosed based on the newly established diagnostic criteria for critically ill patients: Results of a multicenter, prospective survey*
S. Gando, D. Saitoh, H. Ogura, T. Mayumi +11 more
2008Critical Care Medicine236 citations
Semantic Scholar
A randomized, controlled, multicenter trial of the effects of antithrombin on disseminated intravascular coagulation in patients with sepsis
S. Gando, D. Saitoh, H. Ishikura, M. Ueyama +19 more
2013Critical Care172 citations Open access
Semantic Scholar
A Phase 2/3 Trial of Pabinafusp Alfa, IDS Fused with Anti-Human Transferrin Receptor Antibody, Targeting Neurodegeneration in MPS-II
T. Okuyama, Y. Eto, Norio Sakai, Kimitoshi Nakamura +7 more
2020Molecular Therapy156 citations Open access
Semantic Scholar
Multicenter prospective study of procalcitonin as an indicator of sepsis
N. Aikawa, S. Fujishima, Shigeatu Endo, I. Sekine +11 more
2005Journal of Infection and Chemotherapy135 citations
Semantic Scholar
Reevaluation of the efficacy and safety of the neutrophil elastase inhibitor, Sivelestat, for the treatment of acute lung injury associated with systemic inflammatory response syndrome; a phase IV study.
N. Aikawa, A. Ishizaka, H. Hirasawa, S. Shimazaki +7 more
2011Pulmonary Pharmacology & Therapeutics130 citations
Semantic Scholar
Correlation between Plasma Endotoxin, Plasma Cytokines, and Plasminogen Activator Inhibitor-1 Activities in Septic Patients
T. Tani, K. Hanasawa, M. Kodama, H. Imaizumi +12 more
2001World Journal of Surgery111 citations
Semantic Scholar
The Japanese guidelines for the management of sepsis
S. Oda, M. Aibiki, T. Ikeda, H. Imaizumi +8 more
2014Journal of Intensive Care84 citations Open access
Semantic Scholar
SIRS-ASSOCIATED COAGULOPATHY AND ORGAN DYSFUNCTION IN CRITICALLY ILL PATIENTS WITH THROMBOCYTOPENIA
H. Ogura, S. Gando, T. Iba, Y. Eguchi +12 more
2007Shock77 citations Open access
Semantic Scholar
Disseminated intravascular coagulation (DIC) diagnosed based on the Japanese Association for Acute Medicine criteria is a dependent continuum to overt DIC in patients with sepsis.
S. Gando, D. Saitoh, H. Ogura, T. Mayumi +11 more
2009Thrombosis Research72 citations
Semantic Scholar
Usefulness of procalcitonin serum level for the discrimination of severe sepsis from sepsis: a multicenter prospective study
S. Endo, N. Aikawa, S. Fujishima, I. Sekine +12 more
2008Journal of Infection and Chemotherapy62 citations
Semantic Scholar
Autophagy-Related IRGM Polymorphism Is Associated with Mortality of Patients with Severe Sepsis
Tomonori Kimura, Eizo Watanabe, Teruo Sakamoto, O. Takasu +8 more
2014PLoS ONE61 citations Open access
Semantic Scholar
Predicting the severity of systemic inflammatory response syndrome (SIRS)-associated coagulopathy with hemostatic molecular markers and vascular endothelial injury markers.
T. Iba, S. Gando, A. Murata, S. Kushimoto +12 more
2007Journal of Trauma57 citations
Semantic Scholar
Clinical course and outcome of disseminated intravascular coagulation diagnosed by Japanese Association for Acute Medicine criteria
S. Kushimoto, S. Gando, D. Saitoh, H. Ogura +11 more
2008Thrombosis and Haemostasis51 citations
Semantic Scholar
Iduronate-2-sulfatase fused with anti-hTfR antibody, pabinafusp alfa, for MPS-II: A phase 2 trial in Brazil
R. Giugliani, A. Martins, Sairei So, Tatsuyoshi Yamamoto +6 more
2021Molecular Therapy49 citations Open access
Semantic Scholar
Enzyme Replacement Therapy with Pabinafusp Alfa for Neuronopathic Mucopolysaccharidosis II: An Integrated Analysis of Preclinical and Clinical Data
R. Giugliani, A. Martins, T. Okuyama, Y. Eto +12 more
2021International Journal of Molecular Sciences41 citations Open access
Semantic Scholar
Clinical Evaluation of PMX‐DHP for Hypercytokinemia Caused by Septic Multiple Organ Failure
T. Ikeda, Kazumi Ikeda, M. Nagura, H. Taniuchi +5 more
2004Therapeutic apheresis and dialysis39 citations
Semantic Scholar
HMGB-1 as a useful prognostic biomarker in sepsis-induced organ failure in patients undergoing PMX-DHP.
T. Ueno, T. Ikeda, Kazumi Ikeda, H. Taniuchi +3 more
2011Journal of Surgical Research36 citations
Semantic Scholar
Direct hemoperfusion with polymyxin-B-immobilized fiber columns improves septic hypotension and reduces inflammatory mediators in septic patients with colorectal perforation
T. Shimizu, K. Hanasawa, Koichi Sato, M. Umeki +13 more
2009Langenbeck's archives of surgery (Print)33 citations
Semantic Scholar
Usefulness of the endotoxin activity assay as a biomarker to assess the severity of endotoxemia in critically ill patients
T. Ikeda, Kazumi Ikeda, S. Suda, T. Ueno
2014Innate Immunity30 citations Open access
Semantic Scholar
37th International Symposium on Intensive Care and Emergency Medicine (part 3 of 3)
M. von Seth, L. Hillered, A. Otterbeck, K. Hanslin +496 more
2017Critical Care21 citations Open access
Semantic Scholar
Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine
Author Et al, R. Bateman, M. Sharpe, J. E. Jagger +496 more
2016Critical Care21 citations Open access
Semantic Scholar
Changes of cytokines in direct endotoxin adsorption treatment on postoperative multiple organ failure.
N. Matsuno, T. Ikeda, Kazumi Ikeda, K. Hama +7 more
2001Therapeutic apheresis21 citations
Semantic Scholar
Efficacy and Bleeding Risk of Antithrombin Supplementation in Patients With Septic Disseminated Intravascular Coagulation: A Third Survey
T. Iba, S. Gando, D. Saitoh, T. Ikeda +6 more
2017Clinical and applied thrombosis/hemostasis19 citations Open access
Semantic Scholar
Comparative Evaluation of Endotoxin Activity Level and Various Biomarkers for Infection and Outcome of ICU-Admitted Patients
T. Ikeda, H. Kamohara, S. Suda, T. Nagura +3 more
2019Biomedicines17 citations Open access
Semantic Scholar
Successful management by recombinant activated factor VII in a case of disseminated intravascular coagulopathy caused by obstetric hemorrhage
T. Nohira, Yumi Osakabe, S. Suda, Chie Takahashi +4 more
2008The journal of obstetrics and gynaecology research17 citations
Semantic Scholar
A Phase II study of polyclonal anti-TNF-α (AZD9773) in Japanese patients with severe sepsis and/or septic shock
N. Aikawa, Takeshi Takahashi, S. Fujimi, Takeshi Yokoyama +5 more
2013Journal of Infection and Chemotherapy16 citations
Semantic Scholar
Comparison of whole-body cooling and selective head cooling on changes in urinary 8-hydroxy-2-deoxyguanosine levels in patients with global brain ischemia undergoing mild hypothermia therapy
Kazumi Ikeda, T. Ikeda, H. Taniuchi, S. Suda
2012Medical Science Monitor16 citations Open access
Semantic Scholar
C-type natriuretic peptide concentrations in the plasma and cerebrospinal fluid of patients with subarachnoid hemorrhage
Kazumi Ikeda, T. Ikeda, T. Onizuka, H. Terashi +1 more
2000Critical Care14 citations Open access
Semantic Scholar
Reduction in circulating level of HMGB-1 following continuous renal replacement therapy in sepsis.
T. Ueno, T. Ikeda, T. Yokoyama, Y. Kihara +6 more
2016Cytokine13 citations
Semantic Scholar
The Clinical Significance of Serum Procalcitonin Levels following Direct Hemoperfusion with Polymyxin B-Immobilized Fiber Column in Septic Patients with Colorectal Perforation
T. Shimizu, K. Hanasawa, K. Sato, M. Umeki +13 more
2008European Surgical Research11 citations
Semantic Scholar
Superantigen-induced multiple organ dysfunction in a toxin-concentration-controlled and sequential parameter-monitored swine sepsis model.
K. Miwa, Mayumi Fukuyama, N. Matsuno, Shigeru Masuda +3 more
2006International Journal of Infectious Diseases11 citations Open access
Semantic Scholar
Hemoadsorption in critical care.
T. Ikeda
2002Therapeutic apheresis11 citations
Semantic Scholar
Changes in Circulating Levels of Calcitonin Gene-Related Peptide and Nitric Oxide Metabolites in Septic Patients during Direct Hemoperfusion with Polymyxin B-Immobilized Fiber
T. Shimizu, K. Hanasawa, T. Tani, Y. Endo +7 more
2003Blood Purification8 citations
Semantic Scholar
Liver transplantation from non-heart-beating donors: liver procurement without in situ portal flush.
N. Matsuno, M. Uchiyama, E. Sakurai, K. Kozaki +2 more
1996Transplantation Proceedings6 citations
Semantic Scholar
Colloid osmotic pressure (COP) can be a good indicator of occurrence of vasospasm following subarachnoid hemorrhage (SAH).
Kazumi Ikeda, T. Ikeda, Hiramitsu Suzuki, H. Taniuchi +2 more
2003Medical Science Monitor5 citations
Semantic Scholar
Beneficial effect of induced hypothermia on mortality and graft survival in renal transplant patients with severe respiratory failure.
N. Matsuno, T. Nagao, M. Uchiyama, K. Kozaki +3 more
1997Transplantation Proceedings5 citations
Semantic Scholar
Cytokine modulation in abdominal septic shock via the crucial role of IL-6 signaling in endothelial dysfunction
T. Ueno, T. Ikeda, Masaaki Okihara, I. Akashi +7 more
2023Frontiers in Medicine4 citations Open access
Semantic Scholar
A Thrombomodulin Promoter Gene Polymorphism, rs2239562, Influences Both Susceptibility to and Outcome of Sepsis
Eizo Watanabe, O. Takasu, Youichi Teratake, Teruo Sakamoto +10 more
2022Frontiers in Medicine3 citations Open access
Semantic Scholar
Investigation on sivelestat sodium efficacy for acute lung injury at 3 different ICUs
T. Ikeda, S. Endo, M. Miura, M. Matsushita +2 more
20063 citations Open access
Semantic Scholar
Impact of Antithrombin Supplementation and Concomitant Anticoagulation Therapy in Pediatric Patients With Disseminated Intravascular Coagulation
H. Nagafuchi, Y. Eguchi, T. Ikeda
2019Clinical and applied thrombosis/hemostasis2 citations Open access
Semantic Scholar
Exploration of the efficacy of pabinafusp-alfa (JR-141) on neurocognitive development in Hunter syndrome (MPS II): 52-week data from clinical trials in Japan and Brazil
R. Giugliani, A. Martins, T. Okuyama, Y. Eto +10 more
20211 citations
Semantic Scholar
The safety and tolerance of enteral nutrition in severe acute pancreatitis: a multicenter prospective case series study
S. Arata, T. Ikeda, K. Soma, Shirou Miyazawa +8 more
20121 citations Open access
Semantic Scholar
The Effects of Continuous Hemodiafiltration on the Complement Cascade in Severe Sepsis
Kazumi Ikeda, T. Ikeda, M. Nagura, H. Taniuchi +3 more
20041 citations Open access
Semantic Scholar
Effects of endotoxin elimination therapy using polymyxin B immobilized fiber in patients with septic shock after surgical operation
T. Ikeda, Kazumi Ikeda, H. Kaneko, T. Kamei +4 more
1997Critical Care1 citations Open access
Semantic Scholar
Long term efficacy and safety of pabinafusp-alfa (JR-141) in Hunter syndrome (MPS-II): 104-week data from the clinical trials in Japan and Brazil
R. Giugliani, A. Martins, T. Okuyama, Y. Eto +11 more
2022Molecular Genetics and Metabolism0 citations
Semantic Scholar
Drug delivery across the blood-brain barrier and resultant reduction of heparan sulfate in the cerebrospinal fluid in the patients with Hunter syndrome (MPS II): An integrated analysis of 25-week Japanese and Brazilian data on pabinafusp alfa (JR-141)
T. Okuyama, Y. Eto, Norio Sakai, Kimitoshi Nakamura +10 more
2021Molecular Genetics and Metabolism0 citations
Semantic Scholar
Therapy for mucopolysaccharidosis type II with an intravenous blood-brain barrier-crossing enzyme (JR-141): Phase III global clinical trial design
Sairei So, P. Harmatz, Minako Kobayashi, T. Ikeda +7 more
20210 citations
Semantic Scholar
A case of emergency operation of oral warfarin taking patient with good perioperative course by administration of 4 factor prothrombin complex concentrate.
T. Ikeda
20180 citations
Semantic Scholar
敗血症性DICの診断・治療開始基準を再考する―アンチトロンビン製剤の特定使用成績調査の解析から―
Y. Eguchi, T. Ikeda
20170 citations
Semantic Scholar

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Kazumi Ikeda — researcher profile on SciRah
Y. Eguchi×11
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S. Endo×11
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S. Kushimoto×9
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S. Suda — researcher profile on SciRah

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S. Gando — researcher profile on SciRah

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T. Iba — researcher profile on SciRah

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D. Saitoh — researcher profile on SciRah

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K. Okamoto — researcher profile on SciRah

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K. Koseki — researcher profile on SciRah

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T. Mayumi — researcher profile on SciRah

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M. Ueyama — researcher profile on SciRah