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Sarah Keegan · SciRah

Researcher profile · Semantic Scholar

Sarah Keegan

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Sarah Keegan — researcher profile on SciRah

h-index: 21
Works: 47
Citations: 2,775

Most-cited papers

Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma
David J. Clark, S. Dhanasekaran, F. Petralia, Jianbo Pan +76 more
2019Cell660 citations Open access
Semantic Scholar
A robust pipeline for rapid production of versatile nanobody repertoires
Peter C. Fridy, Yinyin Li, Sarah Keegan, Mary K. Thompson +7 more
2014Nature Methods488 citations Open access
Semantic Scholar
Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair
D. A. Reid, Sarah Keegan, Alejandra Leo-Macias, Go Watanabe +7 more
2015Proceedings of the National Academy of Sciences of the United States of America164 citations Open access
Semantic Scholar
Transcription shapes DNA replication initiation and termination in human cells
Yu-Hung Chen, Sarah Keegan, M. Kahli, Peter Tonzi +3 more
2018Nature Structural & Molecular Biology156 citations Open access
Semantic Scholar
CRL4AMBRA1 is a master regulator of D-type cyclins
Daniele Simoneschi, G. Róna, Nan Zhou, Yeon-Tae Jeong +17 more
2021Nature146 citations Open access
Semantic Scholar
Super-resolution imaging reveals that loss of the C-terminus of connexin43 limits microtubule plus-end capture and NaV1.5 localization at the intercalated disc.
E. Agulló-Pascual, Xianming Lin, Alejandra Leo-Macias, Mingliang Zhang +9 more
2014Cardiovascular Research129 citations Open access
Semantic Scholar
BRCA1 and S Phase DNA Repair Pathways Restrict LINE-1 Retrotransposition in Human Cells
P. Mita, Xiao-Ji Sun, D. Fenyö, David J. Kahler +7 more
2020Nature Structural & Molecular Biology94 citations Open access
Semantic Scholar
Nanoscale visualization of functional adhesion/excitability nodes at the intercalated disc
Alejandra Leo-Macias, E. Agulló-Pascual, J. Sanchez-Alonso, Sarah Keegan +8 more
2016Nature Communications93 citations Open access
Semantic Scholar
Super-resolution fluorescence microscopy of the cardiac connexome reveals plakophilin-2 inside the connexin43 plaque.
E. Agulló-Pascual, D. A. Reid, Sarah Keegan, Manavjeet Sidhu +3 more
2013Cardiovascular Research81 citations Open access
Semantic Scholar
The ULK1-FBXW5-SEC23B nexus controls autophagy
Yeon-Tae Jeong, Daniele Simoneschi, Sarah Keegan, D. Melville +9 more
2018bioRxiv74 citations Open access
Semantic Scholar
Rapid, Optimized Interactomic Screening
Zhanna Hakhverdyan, Michal Domanski, L. Hough, Asha A. Oroskar +11 more
2015Nature Methods74 citations Open access
Semantic Scholar
A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors
Anand Venkataraman, Kun Yang, José Irizarry, M. Mackiewicz +51 more
2018Nature Methods62 citations Open access
Semantic Scholar
KaryoCreate: a CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres
Nazario Bosco, Aleah Goldberg, X. Zhao, Joseph C. Mays +24 more
2023Cell61 citations Open access
Semantic Scholar
Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape
Fred D. Mast, Peter C. Fridy, Natalia E. Ketaren, Junjie Wang +25 more
2021eLife61 citations Open access
Semantic Scholar
HIV–host interactome revealed directly from infected cells
Yang Luo, Erica Y. Jacobs, T. Greco, Kevin D. Mohammed +8 more
2016Nature Microbiology53 citations Open access
Semantic Scholar
Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
D. Whelan, W. C. Lee, Yan-Dong Yin, D. Ofri +4 more
2018Nature Communications52 citations Open access
Semantic Scholar
Dissecting the Structural Dynamics of the Nuclear Pore Complex
Zhanna Hakhverdyan, K. Molloy, Sarah Keegan, T. Herricks +8 more
2020Molecules and Cells48 citations Open access
Semantic Scholar
USP1-trapping lesions as a source of DNA replication stress and genomic instability
Kate E. Coleman, Yan-Dong Yin, S. Lui, Sarah Keegan +4 more
2022Nature Communications47 citations Open access
Semantic Scholar
A Method for Quantifying Molecular Interactions Using Stochastic Modelling and Super-Resolution Microscopy
Keria Bermudez-Hernandez, Sarah Keegan, D. Whelan, D. A. Reid +5 more
2017Scientific Reports31 citations Open access
Semantic Scholar
nucGEMs probe the biophysical properties of the nucleoplasm
Tong Shu, Tamás Szórádi, G. Kidiyoor, Ying Xie +12 more
2021bioRxiv30 citations Open access
Semantic Scholar
Structural and Functional Characterization of A Nav1.5-Mitochondrial Couplon.
Marta Pérez-Hernández Duran, Alejandra Leo-Macias, Sarah Keegan, Mariam Jouni +9 more
2020Circulation Research22 citations Open access
Semantic Scholar
CDK-independent role of D-type cyclins in regulating DNA mismatch repair
G. Róna, Bearach Miwatani-Minter, Qing-Yue Zhang, Hailey V. Goldberg +20 more
2024Molecules and Cells20 citations Open access
Semantic Scholar
Condensation of LINE-1 is critical for retrotransposition
Srinjoy Sil, Sarah Keegan, Farida Ettefa, Lance T. Denes +2 more
2023eLife20 citations Open access
Semantic Scholar
Optimizing Selection of Large Animals for Antibody Production by Screening Immune Response to Standard Vaccines
Mary K. Thompson, Peter C. Fridy, Sarah Keegan, B. Chait +2 more
2016JIM - Journal of Immunological Methods20 citations Open access
Semantic Scholar
Dormant origin firing promotes head-on transcription-replication conflicts at transcription termination sites in response to BRCA2 deficiency
Liana J Goehring, Sarah Keegan, Sudipta Lahiri, Wen-Xin Xia +9 more
2024Nature Communications16 citations Open access
Semantic Scholar
A new generation of nanobody research tools using improved mass spectrometry-based discovery methods
Peter C. Fridy, Ryan J. Farrell, K. Molloy, Sarah Keegan +9 more
2024Journal of Biological Chemistry12 citations
Semantic Scholar
GEMspa: a Napari plugin for analysis of single particle tracking data
Sarah Keegan, D. Fenyö, L. Holt
2023bioRxiv11 citations Open access
Semantic Scholar
Monitoring genome-wide replication fork directionality by Okazaki fragment sequencing in mammalian cells
S. Lui, Sarah Keegan, Peter Tonzi, M. Kahli +6 more
2021Nature Protocols10 citations Open access
Semantic Scholar
Nanobody Repertoires for Exposing Vulnerabilities of SARS-CoV-2
Fred D. Mast, Peter C. Fridy, Natalia E. Ketaren, Junjie Wang +24 more
2021bioRxiv9 citations Open access
Semantic Scholar
BDIViz: An Interactive Visualization System for Biomedical Schema Matching with LLM-Powered Validation
Eden Wu, Dishita G. Turakhia, Guan-De Wu, Christos Koutras +6 more
2025IEEE Transactions on Visualization and Computer Graphics6 citations Open access
Semantic Scholar
g2pDB: A Database Mapping Protein Post-Translational Modifications to Genomic Coordinates.
Sarah Keegan, J. Cortens, R. Beavis, D. Fenyö
2016Journal of Proteome Research6 citations
Semantic Scholar
Single Molecule Localization Microscopy of DNA Damage Response Pathways in Cancer
D. Whelan, Yan-Dong Yin, Keria Bermudez-Hernandez, Sarah Keegan +2 more
2016Microscopy and Microanalysis5 citations Open access
Semantic Scholar
Erratum: Nanoscale visualization of functional adhesion/excitability nodes at the intercalated disc
Alejandra Leo-Macias, E. Agulló-Pascual, J. Sanchez-Alonso, Sarah Keegan +8 more
2016Nature Communications5 citations Open access
Semantic Scholar
Genetically encoded multimeric (GEM) nanoparticles probe the biophysical properties of the nucleus
Tamás Szórádi, Tong Shu, Ying Xie, G. Kidiyoor +11 more
2022Biophysical Journal4 citations Open access
Semantic Scholar
The ULK 1-FBXW 5SEC 23 B nexus controls autophagy 1 2 3
Yeon-Tae Jeong, Daniele Simoneschi, Sarah Keegan, D. Melville +12 more
4 citations
Semantic Scholar
Engineered transcription-associated Cas9 targeting in eukaryotic cells
Gregory W. Goldberg, Manjunatha Kogenaru, Sarah Keegan, Max A. B. Haase +8 more
2023bioRxiv3 citations Open access
Semantic Scholar
D-type cyclins regulate DNA mismatch repair in the G1 and S phases of the cell cycle, maintaining genome stability
G. Róna, Bearach Miwatani-Minter, Qing-Yue Zhang, Hailey V. Goldberg +20 more
2024bioRxiv2 citations Open access
Semantic Scholar
Engineered transcription-associated Cas9 targeting in eukaryotic cells
Gregory W. Goldberg, M. Kogenaru, Sarah Keegan, Max A. B. Haase +8 more
2024Nature Communications1 citations Open access
Semantic Scholar
KaryoCreate: a new CRISPR-based technology to generate chromosome-specific aneuploidy by targeting human centromeres
Nazario Bosco, Aleah Goldberg, Adam F. Johnson, Xin Zhao +22 more
2022bioRxiv1 citations Open access
Semantic Scholar
Transcription drives DNA replication initiation and termination in human cells
Yu-Hung Chen, Sarah Keegan, M. Kahli, Peter Tonzi +3 more
2018bioRxiv1 citations Open access
Semantic Scholar
Rethinking the Benign Nature of Class II Lupus Nephritis
Jasmine J. Shwetar, Andrea Fava, Sarah Keegan, Philip M. Carlucci +37 more
2026bioRxiv0 citations Open access
Semantic Scholar
Machine Learning Classification of 53BP1 Foci
María Xóchitl Benítez-Jones, Sarah Keegan, Sebastian Jamshahi, D. Fenyö
2024bioRxiv0 citations Open access
Semantic Scholar
Intricate network of nuclear morphology, chromatin dynamics and macromolecular crowding facilitates efficient nuclear functioning.
G. Kidiyoor, Tamás Szórádi, G. Brittingham, Sarah Keegan +1 more
2023Biophysical Journal0 citations Open access
Semantic Scholar
Author response: The ULK1-FBXW5-SEC23B nexus controls autophagy
Yeon-Tae Jeong, Daniele Simoneschi, Sarah Keegan, D. Melville +9 more
20180 citations Open access
Semantic Scholar
A toolbox of immunoprecipitation-grade monoclonal antibodies against human transcription factors
Anand Venkataraman, Kun Yang, José Irizarry, M. Mackiewicz +50 more
2017bioRxiv0 citations Open access
Semantic Scholar
PNAS Plus Significance Statements
M. Koch, Sara Flür, C. Kreutz, E. Ennifar +17 more
2015Proceedings of the National Academy of Sciences of the United States of America0 citations Open access
Semantic Scholar
Journal Pre-proof A new generation of nanobody research tools using improved mass spectrometry-based discovery methods
Peter C. Fridy, Ryan J. Farrell, K. Molloy, Sarah Keegan +9 more
0 citations
Semantic Scholar

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