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Zhong-Xing Liang · SciRah

Researcher profile · Semantic Scholar

Zhong-Xing Liang

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Zhong-Xing Liang — researcher profile on SciRah

h-index: 25
Works: 71
Citations: 3,441

Most-cited papers

Silencing of CXCR4 blocks breast cancer metastasis.
Zhong-Xing Liang, Y. Yoon, J. Votaw, M. Goodman +2 more
2005Cancer Research429 citations Open access
Semantic Scholar
Inhibition of Breast Cancer Metastasis by Selective Synthetic Polypeptide against CXCR4
Zhong-Xing Liang, Tao Wu, H. Lou, Xi-Wen Yu +5 more
2004Cancer Research359 citations Open access
Semantic Scholar
Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1.
Zhong-Xing Liang, Hui Wu, James Xia, Yuhua Li +7 more
2010Biochemical Pharmacology325 citations
Semantic Scholar
CXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway.
Zhong-Xing Liang, J. Brooks, M. Willard, K. Liang +3 more
2007Biochemical and Biophysical Research Communications - BBRC323 citations Open access
Semantic Scholar
Blockade of invasion and metastasis of breast cancer cells via targeting CXCR4 with an artificial microRNA.
Zhong-Xing Liang, Hui Wu, Santosh Reddy, Ai-Zhi Zhu +5 more
2007Biochemical and Biophysical Research Communications - BBRC139 citations
Semantic Scholar
Cardiac valves in patients with Q fever endocarditis: microbiological, molecular, and histologic studies.
H. Lepidi, P. Houpikian, Zhong-Xing Liang, D. Raoult
2003Journal of Infectious Diseases138 citations
Semantic Scholar
Development of a Unique Small Molecule Modulator of CXCR4
Zhong-Xing Liang, Wei-Qiang Zhan, Ai-Zhi Zhu, Y. Yoon +15 more
2012PLoS ONE131 citations Open access
Semantic Scholar
CXC chemokine receptor-4 antagonist blocks both growth of primary tumor and metastasis of head and neck cancer in xenograft mouse models.
Y. Yoon, Zhong-Xing Liang, Xin Zhang, Mison Choe +6 more
2007Cancer Research126 citations Open access
Semantic Scholar
Regulation of miR-19 to Breast Cancer Chemoresistance Through Targeting PTEN
Zhong-Xing Liang, Yuhua Li, Ke Huang, N. Wagar +1 more
2011Pharmaceutical Research121 citations Open access
Semantic Scholar
Genetic Classification and Differentiation of Bartonella Species Based on Comparison of Partial ftsZ Gene Sequences
Zaher Zeaiter, Zhong-Xing Liang, D. Raoult
2002Journal of Clinical Microbiology121 citations Open access
Semantic Scholar
Whole-brain spectroscopic MRI biomarkers identify infiltrating margins in glioblastoma patients.
J. Cordova, H. Shu, Zhong-Xing Liang, S. Gurbani +8 more
2016Neuro-Oncology113 citations Open access
Semantic Scholar
Discovery of small molecule CXCR4 antagonists.
Wei-Qiang Zhan, Zhong-Xing Liang, Ai-Zhi Zhu, Serdar Kurtkaya +3 more
2007Journal of Medicinal Chemistry109 citations Open access
Semantic Scholar
MicroRNA-302 Replacement Therapy Sensitizes Breast Cancer Cells to Ionizing Radiation
Zhong-Xing Liang, Jeffrey Ahn, D. Guo, J. Votaw +1 more
2012Pharmaceutical Research90 citations Open access
Semantic Scholar
Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model.
Seunghee Kang, Heidi T Cho, Sarojini N. Devi, Zhao-Bin Zhang +10 more
2006Cancer Research81 citations Open access
Semantic Scholar
Lower expression of CXCR4 in lymph node metastases than in primary breast cancers: potential regulation by ligand-dependent degradation and HIF-1alpha.
H. Shim, S. Lau, Sarojini N. Devi, Y. Yoon +2 more
2006Biochemical and Biophysical Research Communications - BBRC76 citations
Semantic Scholar
Dipyrimidine Amines: A Novel Class of Chemokine Receptor Type 4 Antagonists with High Specificity
Ai-Zhi Zhu, Wei-Qiang Zhan, Zhong-Xing Liang, Y. Yoon +8 more
2010Journal of Medicinal Chemistry66 citations Open access
Semantic Scholar
Downregulation of microRNA-206 promotes invasion and angiogenesis of triple negative breast cancer.
Zhong-Xing Liang, Xue-hai Bian, H. Shim
2016Biochemical and Biophysical Research Communications - BBRC64 citations
Semantic Scholar
Potential Biomarker of L-type Amino Acid Transporter 1 in Breast Cancer Progression
Zhong-Xing Liang, Heidi T Cho, L. Williams, Ai-Zhi Zhu +8 more
2011Nuclear medicine and molecular imaging62 citations Open access
Semantic Scholar
Genotypic Characteristics of Two Serotypes of Bartonella henselae
B. La Scola, Zhong-Xing Liang, Zaher Zeaiter, P. Houpikian +2 more
2002Journal of Clinical Microbiology55 citations Open access
Semantic Scholar
Inhibition of breast cancer metastasis with microRNA-302a by downregulation of CXCR4 expression
Zhong-Xing Liang, Xue-hai Bian, H. Shim
2014Breast Cancer Research and Treatment54 citations
Semantic Scholar
HDAC inhibitor suppresses proliferation and invasion of breast cancer cells through regulation of miR-200c targeting CRKL
Xue-hai Bian, Zhong-Xing Liang, Amber Feng, Eric Salgado +1 more
2017Biochemical Pharmacology51 citations Open access
Semantic Scholar
Overexpression of HDAC9 Promotes Invasion and Angiogenesis of Triple Negative Breast Cancer by regulating microRNA-206
Eric Salgado, Xue-hai Bian, Amber Feng, H. Shim +1 more
2018Biochemical and Biophysical Research Communications - BBRC47 citations Open access
Semantic Scholar
CXCR 4 / CXCL 12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway
Zhong-Xing Liang, J. Brooks, M. Willard, K. Liang +3 more
200830 citations
Semantic Scholar
Assessing Treatment Response of Glioblastoma to an HDAC Inhibitor Using Whole-Brain Spectroscopic MRI
S. Gurbani, Y. Yoon, B. Weinberg, Eric Salgado +10 more
2019Tomography27 citations Open access
Semantic Scholar
Silencing of CXCR 4 Blocks Breast Cancer Metastasis
Zhong-Xing Liang, Y. Yoon, J. Votaw, M. Goodman +2 more
200527 citations
Semantic Scholar
Symmetrical bis-tertiary amines as novel CXCR4 inhibitors
Renren Bai, Zhong-Xing Liang, Y. Yoon, Shuangping Liu +5 more
2016European journal of medicinal chemistry23 citations Open access
Semantic Scholar
Benzenesulfonamides: A Unique Class of Chemokine Receptor Type 4 Inhibitors
S. Mooring, Jin Liu, Zhong-Xing Liang, Jeffrey Ahn +4 more
2013ChemMedChem23 citations Open access
Semantic Scholar
Synthesis and evaluation of 2,5 and 2,6 pyridine-based CXCR4 inhibitors.
Theresa Gaines, D. Camp, Renren Bai, Zhong-Xing Liang +3 more
2016Bioorganic & Medicinal Chemistry22 citations Open access
Semantic Scholar
Development of CXCR4 modulators by virtual HTS of a novel amide-sulfamide compound library
Renren Bai, Qi Shi, Zhong-Xing Liang, Y. Yoon +6 more
2016European journal of medicinal chemistry19 citations Open access
Semantic Scholar
Differentiation of Bartonella Species by a Microimmunofluorescence Assay, Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis, and Western Immunoblotting
Zhong-Xing Liang, D. Raoult
2000Clinical Diagnostic Laboratory Immunology19 citations Open access
Semantic Scholar
Monoclonal Antibodies to Immunodominant Epitope of Tropheryma whipplei
Zhong-Xing Liang, B. La Scola, D. Raoult
2002Clinical and Vaccine Immunology17 citations Open access
Semantic Scholar
Discovery of novel aminopiperidinyl amide CXCR4 modulators through virtual screening and rational drug design
Y. Oum, Steven A. Kell, Y. Yoon, Zhong-Xing Liang +2 more
2020European journal of medicinal chemistry16 citations Open access
Semantic Scholar
Novel anti-inflammatory agents targeting CXCR4: Design, synthesis, biological evaluation and preliminary pharmacokinetic study
Renren Bai, Zhong-Xing Liang, Y. Yoon, Eric Salgado +3 more
2017European journal of medicinal chemistry16 citations Open access
Semantic Scholar
A systematic pipeline for the objective comparison of whole-brain spectroscopic MRI with histology in biopsy specimens from grade III glioma
J. Cordova, S. Gurbani, J. Olson, Zhong-Xing Liang +7 more
2016Tomography15 citations Open access
Semantic Scholar
Rickettsia rickettsii Infection in the Pine Vole, Microtus pinetorum
M. Eremeeva, Zhong-Xing Liang, C. Paddock, S. Zaki +3 more
2003Annals of the New York Academy of Sciences15 citations
Semantic Scholar
Amide-sulfamide modulators as effective anti-tumor metastatic agents targeting CXCR4/CXCL12 axis.
Rui Wu, Wenyan Yu, Chuansheng Yao, Zhong-Xing Liang +4 more
2019European journal of medicinal chemistry13 citations
Semantic Scholar
Anti-inflammatory hybrids of secondary amines and amide-sulfamide derivatives
Renren Bai, Jian Sun, Zhong-Xing Liang, Y. Yoon +5 more
2018European journal of medicinal chemistry11 citations Open access
Semantic Scholar
MicroRNA-30c-regulated HDAC9 mediates chemoresistance of breast cancer
Zhong-Xing Liang, Amber Feng, H. Shim
2020Cancer Chemotherapy and Pharmacology10 citations
Semantic Scholar
Development of CXCR4 modulators based on the lead compound RB-108
Renren Bai, Xiaokang Jie, Jian Sun, Zhong-Xing Liang +9 more
2019European journal of medicinal chemistry10 citations Open access
Semantic Scholar
Survival of Stem Cells and Progenitors in the Intestine Is Regulated by LPA5-Dependent Signaling
Zhong-Xing Liang, Pei-Jian He, Yiran Han, C. Yun
2022Cellular and Molecular Gastroenterology and Hepatology9 citations Open access
Semantic Scholar
Compensatory Upregulation of LPA2 and Activation of the PI3K-Akt Pathway Prevent LPA5-Dependent Loss of Intestinal Epithelial Cells in Intestinal Organoids
Zhong-Xing Liang, C. Yun
2022Cells8 citations Open access
Semantic Scholar
A benzenesulfonamide derivative as a novel PET radioligand for CXCR4
Y. Oum, Dinesh Shetty, Y. Yoon, Zhong-Xing Liang +3 more
2019Bioorganic & Medicinal Chemistry8 citations Open access
Semantic Scholar
Synthesis of pyridine derivatives as potential antagonists of chemokine receptor type 4
S. Mooring, Theresa Gaines, Zhong-Xing Liang, H. Shim
2014Heterocyclic Communications8 citations Open access
Semantic Scholar
Production of BartonellaGenus-Specific Monoclonal Antibodies
Zhong-Xing Liang, B. La Scola, H. Lepidi, D. Raoult
2001Clinical Diagnostic Laboratory Immunology7 citations Open access
Semantic Scholar
Synthesis and evaluation of 2,5-furan, 2,5-thiophene and 3,4-thiophene-based derivatives as CXCR4 inhibitors.
Theresa Gaines, F. García, S. Virani, Zhong-Xing Liang +4 more
2019European journal of medicinal chemistry6 citations
Semantic Scholar
LPA5-Dependent Signaling Regulates Regeneration of the Intestinal Epithelium Following Irradiation.
Beth B McConnell, Zhong-Xing Liang, Chad Xu, Yiran Han +1 more
2024American Journal of Physiology - Gastrointestinal and Liver Physiology4 citations Open access
Semantic Scholar
Synthesis and evaluation of 2,5-diamino and 2,5-dianilinomethyl pyridine analogues as potential CXCR4 antagonists.
S. Virani, Zhong-Xing Liang, Y. Yoon, H. Shim +1 more
2019Bioorganic & Medicinal Chemistry Letters3 citations
Semantic Scholar
MSX-122, an orally available small molecule targeting CXCR4, inhibits primary tumor growth in an orthotopic mouse model of lung cancer and improves the effect of paclitaxel
Ya-Wei Zhang, Zhong-Xing Liang, Hui Wu, Ai-Zhi Zhu +3 more
20083 citations
Semantic Scholar
Abstract 5227: Detection of metastatic potential by a novel small molecule F-18 PET imaging agent
Ai-Zhi Zhu, Y. Yoon, Zhong-Xing Liang, R. Voll +3 more
20112 citations
Semantic Scholar
Corrigendum to "Synthesis and evaluation of 2,5-furan, 2,5-thiophene and 3,4-thiophene-based derivatives as CXCR4 inhibitors" [Eur. J. Med. Chem. 181 (2019) 111562].
Theresa Gaines, F. García, S. Virani, Zhong-Xing Liang +4 more
2023European journal of medicinal chemistry1 citations Open access
Semantic Scholar

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