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S. Weldon · SciRah

Researcher profile · Semantic Scholar

S. Weldon

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S. Weldon — researcher profile on SciRah

h-index: 30
Works: 106
Citations: 2,779

Most-cited papers

Docosahexaenoic acid induces an anti-inflammatory profile in lipopolysaccharide-stimulated human THP-1 macrophages more effectively than eicosapentaenoic acid.
S. Weldon, A. Mullen, C. Loscher, L. Hurley +1 more
2007Journal of Nutritional Biochemistry356 citations
Semantic Scholar
Secretory leucoprotease inhibitor binds to NF-κB binding sites in monocytes and inhibits p65 binding
C. Taggart, S. Cryan, S. Weldon, A. Gibbons +5 more
2005Journal of Experimental Medicine252 citations Open access
Semantic Scholar
Decreased Levels of Secretory Leucoprotease Inhibitor in the Pseudomonas-infected Cystic Fibrosis Lung are due to Neutrophil Elastase Degradation
S. Weldon, P. McNally, N. McElvaney, J. Elborn +5 more
2009Journal of Immunology129 citations Open access
Semantic Scholar
The Role of Serine Proteases and Antiproteases in the Cystic Fibrosis Lung
M. Twigg, S. Brockbank, P. Lowry, S. Fitzgerald +2 more
2015Mediators of Inflammation111 citations Open access
Semantic Scholar
SLPI and elafin: multifunctional antiproteases of the WFDC family.
A. Scott, S. Weldon, C. Taggart
2011Biochemical Society Transactions110 citations
Semantic Scholar
Evaluation of the Ability of LL-37 to Neutralise LPS In Vitro and Ex Vivo
A. Scott, S. Weldon, P. Buchanan, B. Schock +6 more
2011PLoS ONE108 citations Open access
Semantic Scholar
Elafin, an Elastase-specific Inhibitor, Is Cleaved by Its Cognate Enzyme Neutrophil Elastase in Sputum from Individuals with Cystic Fibrosis*
N. Guyot, M. Butler, P. McNally, S. Weldon +5 more
2008Journal of Biological Chemistry99 citations Open access
Semantic Scholar
miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production.
S. Weldon, P. McNally, D. McAuley, I. Oglesby +7 more
2014American Journal of Respiratory and Critical Care Medicine84 citations Open access
Semantic Scholar
Cathepsin S: investigating an old player in lung disease pathogenesis, comorbidities, and potential therapeutics
Ryan Brown, Sridesh Nath, A. Lora, G. Samaha +5 more
2020Respiratory Research81 citations Open access
Semantic Scholar
Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma
C. Butler, S. McQuaid, C. Taggart, S. Weldon +8 more
2011Thorax74 citations Open access
Semantic Scholar
Mechanisms of Virus-Induced Airway Immunity Dysfunction in the Pathogenesis of COPD Disease, Progression, and Exacerbation
Guo-Parke Hong, D. Linden, S. Weldon, J. Kidney +1 more
2020Frontiers in Immunology68 citations Open access
Semantic Scholar
Respiratory Syncytial Virus Infections Enhance Cigarette Smoke Induced COPD in Mice
R. Foronjy, A. Dabo, C. Taggart, S. Weldon +1 more
2014PLoS ONE66 citations Open access
Semantic Scholar
Fasciola hepatica-Derived Molecules as Regulators of the Host Immune Response
S. Ryan, J. Shiels, C. Taggart, J. Dalton +1 more
2020Frontiers in Immunology65 citations Open access
Semantic Scholar
Impaired Immune Tolerance to Porphyromonas gingivalis Lipopolysaccharide Promotes Neutrophil Migration and Decreased Apoptosis
S. Zarić, C. Shelburne, R. Darveau, Derek J. Quinn +3 more
2010Infection and Immunity58 citations Open access
Semantic Scholar
Proteases and Their Inhibitors in Chronic Obstructive Pulmonary Disease
T. Dey, J. Kalita, S. Weldon, C. Taggart
2018Journal of Clinical Medicine55 citations Open access
Semantic Scholar
The role of secretory leucoprotease inhibitor in the resolution of inflammatory responses.
S. Weldon, Niamh B. McGarry, C. Taggart, N. McElvaney
2007Biochemical Society Transactions55 citations
Semantic Scholar
Targeting Proteases in Cystic Fibrosis Lung Disease: Paradigms, Progress, and Potential.
M. McKelvey, S. Weldon, D. McAuley, M. Mall +1 more
2020American Journal of Respiratory and Critical Care Medicine54 citations Open access
Semantic Scholar
Protein Phosphatase 2A Reduces Cigarette Smoke-Induced Cathepsin S and Loss of Lung Function.
D. Doherty, Sridesh Nath, J. Poon, R. Foronjy +10 more
2019American Journal of Respiratory and Critical Care Medicine54 citations Open access
Semantic Scholar
The Effect of CFTR Modulators on Airway Infection in Cystic Fibrosis
Caitlyn Harvey, S. Weldon, S. Elborn, D. Downey +1 more
2022International Journal of Molecular Sciences51 citations Open access
Semantic Scholar
Proteases, Mucus, and Mucosal Immunity in Chronic Lung Disease
M. McKelvey, Ryan Brown, S. Ryan, M. Mall +2 more
2021International Journal of Molecular Sciences48 citations Open access
Semantic Scholar
Airway Inflammation and Host Responses in the Era of CFTR Modulators
K. Keown, Ryan Brown, D. Doherty, C. Houston +8 more
2020International Journal of Molecular Sciences47 citations Open access
Semantic Scholar
Activity of innate antimicrobial peptides and ivacaftor against clinical cystic fibrosis respiratory pathogens.
J. Payne, Alice V. Dubois, R. Ingram, S. Weldon +3 more
2017International Journal of Antimicrobial Agents47 citations Open access
Semantic Scholar
The Impact of Aging in Acute Respiratory Distress Syndrome: A Clinical and Mechanistic Overview
Ryan Brown, M. McKelvey, S. Ryan, Shannice Creane +5 more
2020Frontiers in Medicine43 citations Open access
Semantic Scholar
Targeting of cathepsin S reduces cystic fibrosis-like lung disease
Donna M. Small, Ryan Brown, D. Doherty, Anthony Abladey +13 more
2019European Respiratory Journal41 citations Open access
Semantic Scholar
Functional study of elafin cleaved by Pseudomonas aeruginosa metalloproteinases
N. Guyot, G. Bergsson, M. Butler, C. Greene +6 more
2010Biological chemistry40 citations Open access
Semantic Scholar
Type I interferons induce lung protease responses following respiratory syncytial virus infection via RIG-I-like receptors
R. Foronjy, C. Taggart, A. Dabo, S. Weldon +2 more
2014Mucosal Immunology34 citations Open access
Semantic Scholar
Inhibition of ataxia telangiectasia related-3 (ATR) improves therapeutic index in preclinical models of non-small cell lung cancer (NSCLC) radiotherapy.
V. Dunne, M. Ghita, Donna M. Small, Caroline B Coffey +7 more
2017Radiotherapy and Oncology32 citations Open access
Semantic Scholar
A secretory leukocyte protease inhibitor variant with improved activity against lung infection
N. Camper, A. Glasgow, Megan Osbourn, Derek J. Quinn +8 more
2015Mucosal Immunology32 citations Open access
Semantic Scholar
Airway Epithelium Senescence as a Driving Mechanism in COPD Pathogenesis
G. Bateman, Guo-Parke Hong, A. M. Rodgers, D. Linden +4 more
2023Biomedicines31 citations Open access
Semantic Scholar
Cathepsin S Contributes to Lung Inflammation in Acute Respiratory Distress Syndrome.
M. McKelvey, Anthony Abladey, Donna M. Small, D. Doherty +10 more
2022American Journal of Respiratory and Critical Care Medicine29 citations Open access
Semantic Scholar
The Ability of Secretory Leukocyte Protease Inhibitor to Inhibit Apoptosis in Monocytes Is Independent of Its Antiprotease Activity
N. McGarry, C. Greene, N. McElvaney, S. Weldon +1 more
2015Journal of Immunological Research28 citations Open access
Semantic Scholar
INNATE HOST DEFENSE FUNCTIONS OF SECRETORY LEUCOPROTEASE INHIBITOR
S. Weldon, C. Taggart
2007Experimental Lung Research26 citations
Semantic Scholar
A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation.
Donna M. Small, M. Zani, Derek J. Quinn, S. Dallet‐Choisy +7 more
2015Molecular Therapy25 citations Open access
Semantic Scholar
The role of whey acidic protein four-disulfide-core proteins in respiratory health and disease
Donna M. Small, D. Doherty, C. Dougan, S. Weldon +1 more
2017Biological chemistry24 citations Open access
Semantic Scholar
Deciphering Respiratory-Virus-Associated Interferon Signaling in COPD Airway Epithelium
Guo-Parke Hong, D. Linden, S. Weldon, J. Kidney +1 more
2022Medicina21 citations Open access
Semantic Scholar
Schistosoma mansoni immunomodulatory molecule Sm16/SPO-1/SmSLP is a member of the trematode-specific helminth defence molecules (HDMs)
J. Shiels, K. Cwiklinski, R. Alvarado, Karine Thivierge +7 more
2020PLoS Neglected Tropical Diseases20 citations Open access
Semantic Scholar
Sea snake cathelicidin (Hc-cath) exerts a protective effect in mouse models of lung inflammation and infection
Simon R. Carlile, J. Shiels, Lauren Kerrigan, R. Delaney +5 more
2019Scientific Reports20 citations Open access
Semantic Scholar
A role for whey acidic protein four-disulfide-core 12 (WFDC12) in the regulation of the inflammatory response in the lung
A. Glasgow, Donna M. Small, A. Scott, D. McLean +11 more
2015Thorax19 citations Open access
Semantic Scholar
Antiproteases as therapeutics to target inflammation in cystic fibrosis.
Derek J. Quinn, S. Weldon, C. Taggart
2010The Open Respiratory Medicine Journal19 citations Open access
Semantic Scholar
Proteolytic cleavage of elafin by 20S proteasome may contribute to inflammation in acute lung injury
A. Kerrin, S. Weldon, A. Chung, T. Craig +4 more
2012Thorax16 citations Open access
Semantic Scholar
Secretory Leucoprotease Inhibitor (SLPI) Promotes Survival during Acute Pseudomonas aeruginosa Infection by Suppression of Inflammation Rather Than Microbial Killing
Megan Osbourn, A. M. Rodgers, Alice V. Dubois, Donna M. Small +6 more
2022Biomolecules15 citations Open access
Semantic Scholar
Interferon Mediated Bronchial Epithelium Cellular Senescence in Chronic Obstructive Pulmonary Disease.
Guo-Parke Hong, Oisín Cappa, D. Linden, B. Barksby +7 more
2025American Journal of Respiratory Cell and Molecular Biology14 citations Open access
Semantic Scholar
Altered Differentiation and Inflammation Profiles Contribute to Enhanced Innate Responses in Severe COPD Epithelium to Rhinovirus Infection
Guo-Parke Hong, D. Linden, A. Mousnier, I. Scott +6 more
2022Frontiers in Medicine13 citations Open access
Semantic Scholar
Inflammation and host-pathogen interaction: Cause and consequence in cystic fibrosis lung disease.
A. Bragonzi, H. Horati, Lauren Kerrigan, N. Loré +2 more
2017Journal of Cystic Fibrosis13 citations Open access
Semantic Scholar
Preclinical Evaluation of Dose-Volume Effects and Lung Toxicity Occurring In and Out-of-Field.
M. Ghita, V. Dunne, S. McMahon, S. Osman +9 more
2019International Journal of Radiation Oncology, Biology, Physics12 citations Open access
Semantic Scholar
The parasitic 68-mer peptide FhHDM-1 inhibits mixed granulocytic inflammation and airway hyperreactivity in experimental asthma.
A. Tanaka, V. Allam, J. Simpson, N. Tiberti +10 more
2018Journal of Allergy and Clinical Immunology12 citations Open access
Semantic Scholar
Antiproteases as Therapeutics to Target Inflammation in Cystic Fibrosis
Derek J. Quinn, S. Weldon, C. Taggart
2010The Open Respiratory Medicine Journal11 citations Open access
Semantic Scholar
SLPI deficiency alters airway protease activity and induces cell recruitment in a model of muco-obstructive lung disease
Ryan Brown, C. Dougan, P. Ferris, R. Delaney +8 more
2024Frontiers in Immunology9 citations Open access
Semantic Scholar
Therapeutic Inhibition of Cathepsin S Reduces Inflammation and Mucus Plugging in Adult βENaC-Tg Mice
Ryan Brown, Donna M. Small, D. Doherty, L. Holsinger +7 more
2021Mediators of Inflammation9 citations Open access
Semantic Scholar
Cystic fibrosis epithelial cells are primed for apoptosis as a result of increased Fas (CD95).
Qiwei Chen, Sudha Priya Soundara Pandi, Lauren Kerrigan, N. McElvaney +4 more
2018Journal of Cystic Fibrosis9 citations Open access
Semantic Scholar

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