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G. Schnapp · SciRah

Researcher profile · Semantic Scholar

G. Schnapp

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G. Schnapp — researcher profile on SciRah

h-index: 19
Works: 45
Citations: 4,145

Most-cited papers

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint
S. Hauf, R. Cole, S. LaTerra, C. Zimmer +6 more
2003Journal of Cell Biology1,248 citations Open access
Semantic Scholar
Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis
L. Wollin, Eva Wex, A. Pautsch, G. Schnapp +3 more
2015European Respiratory Journal937 citations Open access
Semantic Scholar
Control of Human Telomere Length by TRF1 and TRF2
A. Smogorzewska, B. van Steensel, A. Bianchi, S. Oelmann +3 more
2000Molecular and Cellular Biology824 citations Open access
Semantic Scholar
BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo.
Gopal P. Sapkota, Lorna Cummings, F. Newell, C. Armstrong +8 more
2007Biochemical Journal295 citations Open access
Semantic Scholar
Fast native-SAD phasing for routine macromolecular structure determination
T. Weinert, V. Olieric, S. Waltersperger, E. Panepucci +24 more
2014Nature Methods124 citations
Semantic Scholar
One-step affinity purification protocol for human telomerase
G. Schnapp, H. Rodi, W. Rettig, A. Schnapp +1 more
1998Nucleic Acids Res.101 citations Open access
Semantic Scholar
A systematic approach to increase the efficiency of membrane protein production in cell-free expression systems.
Stefan Haberstock, Christian Roos, Yvette Hoevels, V. Dötsch +3 more
2012Protein Expression and Purification75 citations
Semantic Scholar
Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy
Dianfan Li, N. Howe, Abhiram Dukkipati, S. T. A. Shah +12 more
2014Crystal Growth & Design68 citations Open access
Semantic Scholar
Comparative Analysis of Binding Kinetics and Thermodynamics of Dipeptidyl Peptidase-4 Inhibitors and Their Relationship to Structure.
G. Schnapp, T. Klein, Yvette Hoevels, R. Bakker +1 more
2016Journal of Medicinal Chemistry56 citations Open access
Semantic Scholar
BI-D 1870 is a specific inhibitor of the p 90 RSK ( ribosomal S 6 kinase ) isoforms in vitro and in vivo
Gopal P. Sapkota, Lorna Cummings, F. Newell, C. Armstrong +8 more
200644 citations
Semantic Scholar
Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists.
A. Apel, R. Cheng, C. Tautermann, Michael Brauchle +5 more
2019Structure42 citations Open access
Semantic Scholar
Crystal structure of glucokinase regulatory protein.
A. Pautsch, N. Stadler, Adelheid Löhle, W. Rist +8 more
2013Biochemistry41 citations Open access
Semantic Scholar
MALDI-TOF Mass Spectrometry-Based High-Throughput Screening for Inhibitors of the Cytosolic DNA Sensor cGAS
Roman P. Simon, Martin Winter, C. Kleiner, Robert Ries +9 more
2020SLAS discovery : advancing life sciences R & D39 citations Open access
Semantic Scholar
Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like Molecule.
C. Tautermann, F. Binder, Frank H. Büttner, C. Eickmeier +15 more
2018Journal of Medicinal Chemistry38 citations Open access
Semantic Scholar
Design, synthesis, and evaluation of indolinones as inhibitors of the transforming growth factor β receptor I (TGFβRI).
G. J. Roth, A. Heckel, Trixi Brandl, M. Grauert +7 more
2010Journal of Medicinal Chemistry35 citations Open access
Semantic Scholar
BI 1291583: a novel selective inhibitor of cathepsin C with superior in vivo profile for the treatment of bronchiectasis
S. Kreideweiss, G. Schänzle, G. Schnapp, V. Vintonyak +1 more
2023Inflammation Research29 citations Open access
Semantic Scholar
Structure of the Human Protein Kinase ZAK in Complex with Vemurafenib
S. Mathea, K. Abdul Azeez, E. Salah, C. Tallant +10 more
2016ACS Chemical Biology27 citations Open access
Semantic Scholar
MALDI-TOF-Based Affinity Selection Mass Spectrometry for Automated Screening of Protein–Ligand Interactions at High Throughput
Roman P. Simon, Martin Winter, C. Kleiner, Lucie Wehrle +12 more
2020SLAS discovery : advancing life sciences R & D24 citations Open access
Semantic Scholar
A small-molecule inhibitor of lectin-like oxidized LDL receptor-1 acts by stabilizing an inactive receptor tetramer state
G. Schnapp, H. Neubauer, Frank H. Büttner, S. Handschuh +10 more
2020Communications Chemistry24 citations Open access
Semantic Scholar
Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism
S. O. Dahms, G. Schnapp, Martin Winter, Frank H. Büttner +4 more
2022ACS Chemical Biology16 citations Open access
Semantic Scholar
A Single Second Shell Amino Acid Determines Affinity and Kinetics of Linagliptin Binding to Type 4 Dipeptidyl Peptidase and Fibroblast Activation Protein
G. Schnapp, Yvette Hoevels, R. Bakker, P. Schreiner +2 more
2020ChemMedChem13 citations Open access
Semantic Scholar
Enhancing Drug Residence Time by Shielding of Intra-Protein Hydrogen Bonds: A Case Study on CCR2 Antagonists.
A. Magarkar, G. Schnapp, A. Apel, Daniel Seeliger +1 more
2019ACS Medicinal Chemistry Letters13 citations Open access
Semantic Scholar
Action of Dipeptidyl Peptidase‐4 Inhibitors on SARS‐CoV‐2 Main Protease
H. Nar, G. Schnapp, O. Hucke, T. Hardman +1 more
2020ChemMedChem10 citations Open access
Semantic Scholar
Engineering salt bridge networks between transmembrane helices confers thermostability in G-protein Coupled Receptors
Soumadwip Ghosh, T. Bierig, Sangbae Lee, Suvamay Jana +4 more
2018Journal of Chemical Theory and Computation10 citations Open access
Semantic Scholar
Ligand recognition and activation of neuromedin U receptor 2
Wenli Zhao, Wenru Zhang, Mu Wang, Min-Giang Lu +10 more
2022Nature Communications8 citations Open access
Semantic Scholar
In situ crystallography as an emerging method for structure solution of membrane proteins: the case of CCR2A
R. Cheng, Chia-Ying Huang, M. Hennig, H. Nar +1 more
2020The FEBS Journal5 citations
Semantic Scholar
Protein Production for Three-Dimensional Structural Analysis
M. Bauer, G. Schnapp
20074 citations
Semantic Scholar
In Vitro and In Vivo Characterization of the Novel Cathepsin C Inhibitor BI 1291583
S. Kreideweiss, G. Schaenzle, G. Schnapp, V. Vintonyak +1 more
2022B59. ACUTE LUNG INJURY AND ARDS: CELLS, TISSUES, AND ANIMAL MODELS1 citations
Semantic Scholar
Structure of human FAPalpha in complex with linagliptin
H. Nar, G. Schnapp, P. Schreiner
20211 citations
Semantic Scholar
Front Cover: A Single Second Shell Amino Acid Determines Affinity and Kinetics of Linagliptin Binding to Type 4 Dipeptidyl Peptidase and Fibroblast Activation Protein (ChemMedChem 4/2021)
G. Schnapp, Yvette Hoevels, R. Bakker, P. Schreiner +2 more
2021ChemMedChem0 citations Open access
Semantic Scholar
CRYSTAL STRUCTURE OF LECTIN-LIKE OX-LDL RECEPTOR 1 (C 1 2 1)
H. Nar, D. Fiegen, G. Schnapp
20200 citations
Semantic Scholar
CRYSTAL STRUCTURE OF LECTIN-LIKE OX-LDL RECEPTOR 1 IN COMPLEX WITH BI-0115
H. Nar, D. Fiegen, G. Schnapp
20200 citations
Semantic Scholar
CRYSTAL STRUCTURE OF LECTIN-LIKE OX-LDL RECEPTOR 1 (P212121)
H. Nar, D. Fiegen, G. Schnapp
20200 citations
Semantic Scholar
Inhibition of uPA-uPAR signaling restores respiratory epithelial barrier function in asthma and COPD
M. Webster, V. Schroeder, E. Peter, Ines Kollak +13 more
2019Mechanisms of lung injury and repair0 citations
Semantic Scholar
CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 (STEP) IN COMPLEX WITH COMPOUND 2
S. Hoerer, D. Fiegen, G. Schnapp
20180 citations
Semantic Scholar
CRYSTAL STRUCTURE OF THE MOUSE PROTEIN TYROSINE PHOSPHATASE PTPN5 (STEP) IN COMPLEX WITH COMPOUND BI-0314
D. Fiegen, G. Schnapp
20180 citations
Semantic Scholar
Corrigendum: Fast native-SAD phasing for routine macromolecular structure determination
T. Weinert, V. Olieric, S. Waltersperger, E. Panepucci +24 more
2015Nature Methods0 citations Open access
Semantic Scholar
Crystal structure of glucokinase regulatory protein complexed to phosphate
A. Pautsch, N. Stadler, A. Loehle, M. Lenter +8 more
20130 citations
Semantic Scholar
Crystal structure of TGFbRI complexed with an indolinone inhibitor
G. J. Roth, A. Heckel, Trixi Brandl, M. Grauert +7 more
20100 citations
Semantic Scholar
BI-D 1870 is a specific inhibitor of the p 90 Ribosomal S 6 Kinase ( RSK ) isoforms in vitro and in vivo
Gopal P. Sapkota, F. Newell, C. Armstrong, J. Bain +7 more
20060 citations
Semantic Scholar
Pyrimidine derivatives, medicaments containing these compounds, their use and processes for their preparation
G. Dahmann, F. Himmelsbach, H. Wittneben, A. Pautsch +8 more
20020 citations
Semantic Scholar
Pyrimidine derivatives, pharmaceutical agents containing said compounds, use and method for generation.
G. Dahmann, F. Himmelsbach, B. Krist, M. Lenter +8 more
20020 citations
Semantic Scholar
Pyrimidine derivatives, pharmaceutical compounds containing them, their use and processes for their preparation
G. Dahmann, F. Himmelsbach, H. Wittneben, A. Pautsch +8 more
20020 citations
Semantic Scholar
New dihydropteridinoner, process for preparing these and their use as medicament
M. Hoffmann, M. Grauert, Steffen Breitfelder, C. Eickmeier +7 more
20020 citations
Semantic Scholar
Characteristics of alumina powders prepared by the urea-formaldehyde polymeric route : 1. Effect of ultrasonic treatment
D. M. Ibrahim, A. Mostafa, T. Khalil, J. Bossert +1 more
20000 citations
Semantic Scholar

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H. Nar×13
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D. Fiegen×8
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