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W. V. van Ijcken · SciRah

Researcher profile · Semantic Scholar

W. V. van Ijcken

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W. V. van Ijcken — researcher profile on SciRah

h-index: 76
Works: 363
Citations: 21K

Most-cited papers

Steroid-resistant human inflammatory ILC2s are marked by CD45RO and elevated in type 2 respiratory diseases
E. K. van der Ploeg, K. Golebski, M. van Nimwegen, J. Fergusson +18 more
2021Science immunology113 citations Open access
Semantic Scholar
PD-L1 checkpoint blockade promotes regulatory T cell activity that underlies therapy resistance
Mandy van Gulijk, A. van Krimpen, Sjoerd T. T. Schetters, Mike Eterman +17 more
2023Science immunology88 citations Open access
Semantic Scholar
Orphan CpG islands amplify poised enhancer regulatory activity and determine target gene responsiveness
Tomás Pachano, Víctor Sánchez-Gaya, Thais Ealo, María Mariner-Faulí +9 more
2021Nature Genetics86 citations Open access
Semantic Scholar
Temozolomide and radiotherapy versus radiotherapy alone in patients with glioblastoma, IDH-wildtype: post-hoc analysis of the EORTC randomized phase 3 CATNON trial
C. M. S. Tesileanu, M. Sanson, W. Wick, A. Brandes +33 more
2022Clinical Cancer Research48 citations Open access
Semantic Scholar
Dominant-acting CSF1R variants cause microglial depletion and altered astrocytic phenotype in zebrafish and adult-onset leukodystrophy
W. Berdowski, H. C. van der Linde, M. Breur, N. Oosterhof +13 more
2022Acta Neuropathologica37 citations Open access
Semantic Scholar
3D chromatin reprogramming primes human memory TH2 cells for rapid recall and pathogenic dysfunction
A. Schoonhoven, M. D. de Bruijn, B. Stikker, R. Brouwer +7 more
2023Science immunology34 citations Open access
Semantic Scholar
High-throughput and affordable genome-wide methylation profiling of circulating cell-free DNA by methylated DNA sequencing (MeD-seq) of LpnPI digested fragments
T. Deger, R. Boers, V. de Weerd, L. Angus +12 more
2021Clinical Epigenetics31 citations Open access
Semantic Scholar
Human Pluripotent Stem Cell-Derived Astrocyte Functionality Compares Favorably with Primary Rat Astrocytes
B. Lendemeijer, M. Unkel, H. Smeenk, B. Mossink +11 more
2024eNeuro27 citations Open access
Semantic Scholar
Genome-wide aberrant methylation in primary metastatic UM and their matched metastases
Kyra N. Smit, R. Boers, J. Vaarwater, J. Boers +7 more
2022Scientific Reports27 citations Open access
Semantic Scholar
Split Pool Ligation-based Single-cell Transcriptome sequencing (SPLiT-seq) data processing pipeline comparison
L. Kuijpers, Bastian V. H. Hornung, M. C. G. N. van den Hout-van Vroonhoven, W. V. van Ijcken +2 more
2024BMC Genomics24 citations Open access
Semantic Scholar
USP7 regulates the ncPRC1 Polycomb axis to stimulate genomic H2AK119ub1 deposition uncoupled from H3K27me3
A. Sijm, Y. Atlasi, J. A. van der Knaap, Joyce Wolf van der Meer +8 more
2022Science Advances23 citations Open access
Semantic Scholar
Retrospective analysis of enhancer activity and transcriptome history
R. Boers, J. Boers, B. Tan, M. V. van Leeuwen +10 more
2021bioRxiv23 citations Open access
Semantic Scholar
PDGFRβ+ cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny
Diana Sá da Bandeira, A. Kilpatrick, Madalena Marques, M. Gomez-Salazar +16 more
2022Cell Reports22 citations Open access
Semantic Scholar
Comparative single-cell RNA-sequencing profiling of BMP4-treated primary glioma cultures reveals therapeutic markers
I. Verploegh, A. Conidi, R. Brouwer, H. E. Balcioglu +8 more
2022Neuro-Oncology22 citations Open access
Semantic Scholar
Molecular and behavioral consequences of Ube3a gene overdosage in mice
A. Punt, Matthew C. Judson, Michael S. Sidorov, Brittany Williams +11 more
2022JCI Insight21 citations Open access
Semantic Scholar
Multi-Omics Profiling in Marfan Syndrome: Further Insights into the Molecular Mechanisms Involved in Aortic Disease
J. Verhagen, J. Burger, J. Bekkers, A. T. den Dekker +13 more
2021International Journal of Molecular Sciences20 citations Open access
Semantic Scholar
Unraveling the Genetics of Congenital Diaphragmatic Hernia: An Ongoing Challenge
E. Brosens, N. Peters, Kim S. van Weelden, Charlotte Bendixen +14 more
2022Frontiers in Pediatrics19 citations Open access
Semantic Scholar
Circulating TP53 mutations are associated with early tumor progression and poor survival in pancreatic cancer patients treated with FOLFIRINOX
F. van der Sijde, Z. Azmani, M. Besselink, B. Bonsing +14 more
2021Therapeutic Advances in Medical Oncology17 citations Open access
Semantic Scholar
Runx1+ vascular smooth muscle cells are essential for hematopoietic stem and progenitor cell development in vivo
Zaniah N. Gonzalez Galofre, A. Kilpatrick, Madalena Marques, Diana Sá da Bandeira +12 more
2024Nature Communications16 citations Open access
Semantic Scholar
The tumor suppressor MIR139 is silenced by POLR2M to promote AML oncogenesis
Christiaan J. Stavast, Iris van Zuijen, Elena Karkoulia, Arman Özçelik +15 more
2021Leukemia16 citations Open access
Semantic Scholar
JMJD3 intrinsically disordered region links the 3D-genome structure to TGFβ-dependent transcription activation
Marta Vicioso-Mantis, R. Fueyo, C. Navarro, Sara Cruz-Molina +4 more
2022Nature Communications15 citations Open access
Semantic Scholar
Molecular analysis of the erythroid phenotype of a patient with BCL11A haploinsufficiency.
M. Wessels, M. Cnossen, T. V. van Dijk, N. Gillemans +14 more
2021Blood Advances14 citations Open access
Semantic Scholar
Epigenomic partitioning of a polygenic risk score for asthma reveals distinct genetically driven disease pathways
B. Stikker, Lianne Trap, B. Sedaghati-Khayat, M. D. de Bruijn +7 more
2024European Respiratory Journal13 citations Open access
Semantic Scholar
Epigenomic analysis of KLF1 haploinsufficiency in primary human erythroblasts
S. Heshusius, Laura Grech, N. Gillemans, R. Brouwer +9 more
2022Scientific Reports13 citations Open access
Semantic Scholar
Heritability and De Novo Mutations in Oesophageal Atresia and Tracheoesophageal Fistula Aetiology
E. Brosens, R. Brouwer, H. Douben, Y. van Bever +6 more
2021Genes12 citations Open access
Semantic Scholar
Epigenetic and Genomic Hallmarks of PARP-Inhibitor Resistance in Ovarian Cancer Patients
Tugce Senturk Kirmizitas, C. B. van den Berg, R. Boers, J. Helmijr +16 more
2024Genes11 citations Open access
Semantic Scholar
Mutation Analysis of Pancreatic Juice and Plasma for the Detection of Pancreatic Cancer
I. Levink, M. Jansen, Z. Azmani, W. V. van Ijcken +5 more
2023International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Bulk and single-cell transcriptomics identify gene signatures of stem cell-derived NK cell donors with superior cytolytic activity
A. V. van Vliet, M. van den Hout, D. Steenmans, A. Duru +5 more
2024Molecular therapy. Oncology10 citations Open access
Semantic Scholar
Species-specific responses during Seoul orthohantavirus infection in human and rat lung microvascular endothelial cells
Danny Noack, M. van den Hout, C. Embregts, W. V. van Ijcken +2 more
2024PLoS Neglected Tropical Diseases10 citations Open access
Semantic Scholar
Comparison of Single Cell Transcriptome Sequencing Methods: Of Mice and Men
Bastian V. H. Hornung, Z. Azmani, A. T. den Dekker, E. Oole +4 more
2023Genes10 citations Open access
Semantic Scholar
Rabies virus uniquely reprograms the transcriptome of human monocyte-derived macrophages
C. Embregts, Annelieke S. Wentzel, A. T. den Dekker, W. V. van Ijcken +2 more
2023Frontiers in Cellular and Infection Microbiology10 citations Open access
Semantic Scholar
Interplay between FLI-1 and the LDB1 complex in murine erythroleukemia cells and during megakaryopoiesis
Guillaume Giraud, Petros Kolovos, Ilias Boltsis, J. van Staalduinen +5 more
2021iScience10 citations Open access
Semantic Scholar
Butyrate Selectively Targets Super‐Enhancers and Transcriptional Networks Associated with Human Mast Cell Function
Jelle Folkerts, M. D. de Bruijn, W. V. van Ijcken, Rudi W. Hendriks +1 more
2025European Journal of Immunology9 citations Open access
Semantic Scholar
CXCL10 Secreted by Pericytes Mediates TNFα-Induced Vascular Leakage in Tumors and Enhances Extravasation of Nanoparticle-Based Chemotherapeutics
A. L. Seynhaeve, Hui Liu, Marjolein I Priester, Mike Valentijn +8 more
2025Cancer Research8 citations Open access
Semantic Scholar
Distinctive cell‐free DNA methylation characterizes presymptomatic genetic frontotemporal dementia
Lucia A. A. Giannini, R. Boers, E. L. van der Ende, J. Poos +11 more
2024Annals of Clinical and Translational Neurology8 citations Open access
Semantic Scholar
CABA-V7: a prospective biomarker selected trial of cabazitaxel treatment in AR-V7 positive prostate cancer patients.
K. Isebia, B. Mostert, B. Belderbos, S. Buck +20 more
2022European Journal of Cancer8 citations Open access
Semantic Scholar
A non-syndromic orofacial cleft risk locus links tRNA splicing defects to neural crest cell pathologies.
Michaela Bartusel, Skylar X. Kim, Rizwan Rehimi, Alicia M. Darnell +13 more
2025American Journal of Human Genetics7 citations Open access
Semantic Scholar
Effect of bovine milk fat-based infant formulae on microbiota, metabolites and stool parameters in healthy term infants in a randomized, crossover, placebo-controlled trial
Ellen Looijesteijn, R. Brouwer, R. Schoemaker, L. Ulfman +5 more
2022BMC Nutrition7 citations Open access
Semantic Scholar
A multiplex pedigree with pathologically confirmed multiple system atrophy and Parkinson’s disease with dementia
A. Fanciulli, Fabian Leys, Fabienne Lehner, V. Sidoroff +22 more
2022Brain Communications7 citations Open access
Semantic Scholar
KIF2A stabilizes intercellular bridge microtubules to maintain mouse embryonic stem cell cytokinesis.
Lieke Stockmann, Hélène Kabbech, G. Kremers, Brent van Herk +9 more
2025Journal of Cell Biology6 citations Open access
Semantic Scholar
Unprecedented male relative differentiation with Y-SNVs from whole genome sequencing.
Dion Zandstra, Arwin Ralf, Zeliha Ozgur, W. V. van Ijcken +2 more
2025Forensic Science International: Genetics6 citations Open access
Semantic Scholar
Unraveling the impact of AXIN1 mutations on HCC development: Insights from CRISPR/Cas9 repaired AXIN1-mutant liver cancer cell lines
Ruyi Zhang, Shan Li, Kelly Schippers, Boaz Eimers +6 more
2024PLoS ONE6 citations Open access
Semantic Scholar
Genome-wide analysis toward the epigenetic aetiology of myelodysplastic syndrome disease progression and pharmacoepigenomic basis of hypomethylating agents drug treatment response
Stavroula Siamoglou, R. Boers, M. Koromina, J. Boers +9 more
2023Human Genomics6 citations Open access
Semantic Scholar
Targeted Genomic Sequencing of TSC1 and TSC2 Reveals Causal Variants in Individuals for Whom Previous Genetic Testing for Tuberous Sclerosis Complex Was Normal
H. D. West, M. Nellist, R. Brouwer, M. C. G. N. van den Hout-van Vroonhoven +17 more
2023Human Mutation6 citations Open access
Semantic Scholar
Single-Cell RNA Sequencing of Donor-Reactive T Cells Reveals Role of Apoptosis in Donor-Specific Hyporesponsiveness of Kidney Transplant Recipients
Amy C. J. van der List, N. Litjens, R. Brouwer, M. Klepper +3 more
2023International Journal of Molecular Sciences6 citations Open access
Semantic Scholar
Liquid Biopsies for Colorectal Cancer and Advanced Adenoma Screening and Surveillance: What to Measure?
E. Eikenboom, S. Wilting, T. Deger, M. Srebniak +10 more
2023Cancers6 citations Open access
Semantic Scholar
Rapid specification of human pluripotent stem cells to functional astrocytes
B. Lendemeijer, M. Unkel, B. Mossink, S. Hijazi +10 more
2022bioRxiv5 citations Open access
Semantic Scholar
BRAIN-MAGNET: A functional genomics atlas for interpretation of non-coding variants.
Rui-Zhi Deng, E. Perenthaler, A. Nikoncuk, S. Yousefi +13 more
2025Cell4 citations Open access
Semantic Scholar
A CHD8-TRRAP axis facilitates MYC and E2F target gene regulation in human neural stem cells
Lize Meert, Mariana Pelicano de Almeida, Mike R. Dekker, D. Dekkers +8 more
2025iScience4 citations Open access
Semantic Scholar
X-chromosome upregulation operates on a gene-by-gene basis at RNA and protein levels
Ryan N. Allsop, Jeffrey Boeren, B. Tan, Sarra Merzouk +7 more
2025bioRxiv4 citations Open access
Semantic Scholar

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