Researcher profile · Semantic Scholar

Yu-Chen Lo

h-index: 16
Works: 36
Citations: 1,461

Most-cited papers

Machine learning in chemoinformatics and drug discovery
Yu-Chen Lo, Stefano E. Rensi, Wen Torng, R. Altman
2018Drug Discovery Today804 citations Open access
Semantic Scholar
The STARD9/Kif16a Kinesin Associates With Mitotic Microtubules and Regulates Spindle Pole Assembly
J. Z. Torres, Matthew K. Summers, David A. Peterson, M. Brauer +10 more
2011Cell86 citations Open access
Semantic Scholar
Large-Scale Chemical Similarity Networks for Target Profiling of Compounds Identified in Cell-Based Chemical Screens
Yu-Chen Lo, Silvia Senese, Chien-Ming Li, Qi-Yang Hu +3 more
2015PLoS Comput. Biol.64 citations Open access
Semantic Scholar
Chemical dissection of the cell cycle: probes for cell biology and anti-cancer drug development
Silvia Senese, Yu-Chen Lo, Dian Huang, T. Zangle +8 more
2014Cell Death and Disease58 citations Open access
Semantic Scholar
Fatostatin Inhibits Cancer Cell Proliferation by Affecting Mitotic Microtubule Spindle Assembly and Cell Division*
Ankur A. Gholkar, Keith Cheung, K. Williams, Yu-Chen Lo +5 more
2016Journal of Biological Chemistry56 citations Open access
Semantic Scholar
Homology modeling of TMPRSS2 yields candidate drugs that may inhibit entry of SARS-CoV-2 into human cells.
Stefano E. Rensi, Allison M. Keys, Yu-Chen Lo, Alexander Derry +3 more
2020ChemRxiv51 citations Open access
Semantic Scholar
3D Chemical Similarity Networks for Structure-Based Target Prediction and Scaffold Hopping
Yu-Chen Lo, Silvia Senese, R. Damoiseaux, J. Z. Torres
2016ACS Chemical Biology51 citations Open access
Semantic Scholar
The Mid2 X-linked Intellectual Disability Ubiquitin Ligase Associates with Astrin and Regulates Astrin Levels to Promote Cell Division
Ankur A. Gholkar, Silvia Senese, Yu-Chen Lo, Edmundo G. Vides +5 more
2015Cell Reports35 citations Open access
Semantic Scholar
A cancer biologist’s primer on machine learning applications in high-dimensional cytometry
Timothy J. Keyes, P. Domizi, Yu-Chen Lo, G. Nolan +1 more
2020Cytometry Part A28 citations Open access
Semantic Scholar
Pocket similarity identifies selective estrogen receptor modulators as microtubule modulators at the taxane site
Yu-Chen Lo, Olga Cormier, Tian-Yun Liu, K. Nettles +3 more
2019Nature Communications28 citations Open access
Semantic Scholar
Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential
Yu-Chen Lo, Silvia Senese, B. France, Ankur A. Gholkar +2 more
2017Scientific Reports28 citations Open access
Semantic Scholar
Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis
Ankur A. Gholkar, Silvia Senese, Yu-Chen Lo, Joseph R. Capri +7 more
2015Cell Cycle28 citations Open access
Semantic Scholar
Computational analysis of kinase inhibitor selectivity using structural knowledge
Yu-Chen Lo, Tian-Yun Liu, K. Morrissey, Satoko Kakiuchi-Kiyota +5 more
2018Bioinform.25 citations Open access
Semantic Scholar
CytofIn enables integrated analysis of public mass cytometry datasets using generalized anchors
Yu-Chen Lo, Timothy J. Keyes, Astraea Jager, J. Sarno +9 more
2022Nature Communications20 citations Open access
Semantic Scholar
The Implementation of Green Tourism and Hospitality
Shwn-meei Lee, H. Honda, Gui Ren, Yu-Chen Lo
201620 citations Open access
Semantic Scholar
A unique insertion in STARD9's motor domain regulates its stability
Silvia Senese, Keith Cheung, Yu-Chen Lo, Ankur A. Gholkar +3 more
2015Molecular Biology of the Cell19 citations Open access
Semantic Scholar
Chemical Similarity Networks for Drug Discovery
Yu-Chen Lo, J. Z. Torres
201613 citations Open access
Semantic Scholar
tidytof: a user-friendly framework for scalable and reproducible high-dimensional cytometry data analysis
Timothy J. Keyes, Abhishek Koladiya, Yu-Chen Lo, Garry P. Nolan +1 more
2023Bioinformatics Advances12 citations Open access
Semantic Scholar
Microtubins: a novel class of small synthetic microtubule targeting drugs that inhibit cancer cell proliferation
Silvia Senese, Yu-Chen Lo, Ankur A. Gholkar, Chien-Ming Li +5 more
2017OncoTarget10 citations Open access
Semantic Scholar
Artificial Intelligence-Based Drug Design and Discovery
Yu-Chen Lo, Gui Ren, H. Honda, K. Davis
2019Cheminformatics and its Applications8 citations Open access
Semantic Scholar
Single-cell technologies uncover intra-tumor heterogeneity in childhood cancers
Yu-Chen Lo, Yuxuan Liu, Marte B. Kammersgaard, Abhishek Koladiya +2 more
2023Seminars in Immunopathology7 citations
Semantic Scholar
Regulation of Iron Homeostasis Through Parkin-mediated Lactoferrin Ubiquitylation
Ankur A. Gholkar, S. Schmollinger, Erick F. Velasquez, Yu-Chen Lo +8 more
2020bioRxiv7 citations Open access
Semantic Scholar
Leukemia Cell Cycle Chemical Profiling Identifies the G2-phase Leukemia Specific Inhibitor Leusin-1
Xiaoyu Xia, Yu-Chen Lo, Ankur A. Gholkar, Silvia Senese +4 more
2019ACS Chemical Biology5 citations Open access
Semantic Scholar
Benefit of a Short Chain Peptide as a Targeting Ligand of Nanocarriers for a Brain-Driven Purpose
Yu-Chen Lo, Wen Lin
2021Pharmaceutics4 citations Open access
Semantic Scholar
Chemical Dissection of the Cell Cycle for Anticancer Drug Discovery and Target Identification
Yu-Chen Lo
20161 citations
Semantic Scholar
Quantitative Methods in System-Based Drug Discovery
Yu-Chen Lo, Ren Gui, H. Honda, J. Z. Torres
20161 citations Open access
Semantic Scholar
Scanning electron microscopes and the comparison of tephritid flies
Hiroshi Honda, E. Parish, Tsao-Yi Wei, Yu-Chen Lo +1 more
20200 citations Open access
Semantic Scholar
Computational chemistry and computer-assisted application of calculation for steroids
Hiroshi Honda, Yu-Chen Lo, Tsao-Yi Wei, Gui Ren +2 more
20200 citations Open access
Semantic Scholar
Chemical synthesis of polycyclic electron-donor for nanoelectronic materials study
Yu-Chen Lo, Hiroshi Honda, Meen-Woon Hsiao, E. Parish +2 more
20200 citations Open access
Semantic Scholar
Contributors
B. A. Akhoon, Marta E. Alarcón-Riquelme, L. N. Alberca, Juan I. Alice +99 more
2019In Silico Drug Design0 citations
Semantic Scholar
In Silico Repurposing of Cell Cycle Modulators for Cancer Treatment
Yu-Chen Lo, J. Z. Torres
2019In Silico Drug Design0 citations
Semantic Scholar
Novel Discovery of the Relationship of Clinical Phenotype of Coronary Heart Disease with Retinol Binding Protein 4, Lipoprotein-Related Phospholipase A2
Liutova Lv, Yang-zhang Tang, Shi-Qiang Wang, Gui Ren +3 more
20170 citations Open access
Semantic Scholar
A Novel Innovation to Statistical Analysis Using Structural Equation Modeling on Management Strategies
Gui Ren, Yann-Huang, Jeng-Dau Wu, Yu-Chen Lo +1 more
20170 citations
Semantic Scholar
Title 3 D Chemical Similarity Networks for Structure-Based Target Prediction and Scaffold Hopping
Yu-Chen Lo, Silvia Senese, R. Damoiseaux, J. Z. Torres
20160 citations
Semantic Scholar
Computer-Aided Biosensor Design
Yu-Chen Lo, Ren Gui, H. Honda, J. Z. Torres
20160 citations Open access
Semantic Scholar
and is required for ciliogenesis.
Ankur A. Gholkar, Silvia Senese, Yu-Chen Lo, Joseph R. Capri +7 more
20150 citations
Semantic Scholar

Gui Ren

×7

H. Honda×6

K. Davis×5

R. Altman×4

Joseph R. Capri×4

J. Whitelegge×4

Timothy J. Keyes×4

E. Parish×4