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Jun Pei · SciRah

Researcher profile · Semantic Scholar

Jun Pei

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Jun Pei — researcher profile on SciRah

h-index: 4
Works: 8
Citations: 33

Most-cited papers

Revealing the mechanism of action of a first-in-class covalent inhibitor of KRASG12C (ON) and other functional properties of oncogenic KRAS by 31P NMR
Alok K. Sharma, Jun Pei, Yue Yang, M. Dyba +12 more
2024Journal of Biological Chemistry16 citations Open access
Semantic Scholar
Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
Carlos Stahlhut, A. Maciag, Kyle A Sullivan, Kanchan Singh +32 more
2026Cancer Discovery5 citations Open access
Semantic Scholar
Abstract 4378: BBO-11818, an orally bioavailable, highly potent and non-covalent pan-KRAS inhibitor demonstrates robust anti-tumor activity in KRAS-mutant preclinical models
Carlos E. Stahlhut Espinosa, Kanchan Singh, Zuhui Zhang, Kyle A Sullivan +27 more
2025Cancer Research5 citations
Semantic Scholar
How KRAS Mutations Impair Intrinsic GTP Hydrolysis: Experimental and Computational Investigations
L. Song, Dana Rabara, Semiha Kevser Bali, Jun Pei +6 more
2025Journal of Chemical Information and Modeling5 citations
Semantic Scholar
Discovery of NTQ2494, a potent and orally bioavailable inhibitor of AXL kinase for the treatment of human tumors.
Lin-Lin Zhang, Ben Niu, Dong-Hui Chen, Bin Wang +12 more
2026European journal of medicinal chemistry1 citations
Semantic Scholar
Abstract 7104: BBO-11818: An orally bioavailable, highly potent and selective non-covalent pan-KRAS(ON) and (OFF) inhibitor with robust anti-tumor activity in KRAS-mutant preclinical models
Carlos E. Stahlhut Espinosa, A. Maciag, Kyle A Sullivan, Kanchan Singh +33 more
2026Cancer Research1 citations
Semantic Scholar
Abstract A063: BBO-11818: an orally bioavailable, highly potent and selective non-covalent pan-KRAS(ON) and (OFF) inhibitor with robust anti-tumor activity in KRAS-mutant preclinical models
Carlos Stahlhut, A. Maciag, Kyle A Sullivan, Kanchan Singh +32 more
2025Molecular Cancer Therapeutics1 citations
Semantic Scholar
Abstract A047: KRAS G12C and G12D mutants exhibit distinct conformational flexibility in the helix 3–switch 2 pocket that drives differential protein function
Alok K. Sharma, Megan Rigby, Marco Tonelli, Nicole Fer +17 more
2026Cancer Research0 citations
Semantic Scholar

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Yue Yang×7
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Dana Rabara×7
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Erik K. Larsen×6
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Alok K. Sharma×5

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