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P. Hahnfeldt · SciRah

Researcher profile · Semantic Scholar

P. Hahnfeldt

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P. Hahnfeldt — researcher profile on SciRah

h-index: 43
Works: 113
Citations: 8,326

Most-cited papers

Clinical application of antiangiogenic therapy: microvessel density, what it does and doesn't tell us.
L. Hlatky, P. Hahnfeldt, J. Folkman
2002Journal of the National Cancer Institute820 citations
Semantic Scholar
Tumor development under angiogenic signaling: a dynamical theory of tumor growth, treatment response, and postvascular dormancy.
P. Hahnfeldt, D. Panigrahy, J. Folkman, L. Hlatky
1999Cancer Research750 citations
Semantic Scholar
Classical Mathematical Models for Description and Prediction of Experimental Tumor Growth
S. Benzekry, Clare Lamont, A. Beheshti, A. Tracz +3 more
2014PLoS Comput. Biol.588 citations Open access
Semantic Scholar
Endostatin's antiangiogenic signaling network.
A. Abdollahi, P. Hahnfeldt, C. Maercker, H. Grone +5 more
2004Molecules and Cells414 citations Open access
Semantic Scholar
PPARγ ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis
D. Panigrahy, S. Singer, Lucy Q. Shen, C. Butterfield +11 more
2002413 citations Open access
Semantic Scholar
Her-2-neu expression and progression toward androgen independence in human prostate cancer.
S. Signoretti, R. Montironi, J. Manola, A. Altimari +9 more
2000Journal of the National Cancer Institute401 citations
Semantic Scholar
Simple ODE models of tumor growth and anti-angiogenic or radiation treatment
R. Sachs, L. Hlatky, P. Hahnfeldt
2001249 citations Open access
Semantic Scholar
Transcriptional network governing the angiogenic switch in human pancreatic cancer
A. Abdollahi, C. Schwager, J. Kleeff, I. Esposito +10 more
2007Proceedings of the National Academy of Sciences of the United States of America234 citations Open access
Semantic Scholar
The linear-quadratic model and most other common radiobiological models result in similar predictions of time-dose relationships.
David J. Brenner, L. Hlatky, P. Hahnfeldt, Y. Huang +1 more
1998Radiation Research232 citations
Semantic Scholar
Cancer: looking outside the genome
J. Folkman, P. Hahnfeldt, L. Hlatky
2000Nature reviews. Molecular cell biology203 citations
Semantic Scholar
Paradoxical dependencies of tumor dormancy and progression on basic cell kinetics.
H. Enderling, A. Anderson, M. Chaplain, A. Beheshti +2 more
2009Cancer Research189 citations Open access
Semantic Scholar
Combined therapy with direct and indirect angiogenesis inhibition results in enhanced antiangiogenic and antitumor effects.
A. Abdollahi, K. Lipson, A. Sckell, H. Zieher +11 more
2003Cancer Research172 citations
Semantic Scholar
SU5416 and SU6668 attenuate the angiogenic effects of radiation-induced tumor cell growth factor production and amplify the direct anti-endothelial action of radiation in vitro.
A. Abdollahi, K. Lipson, Xiao-Hong Han, R. Krempien +7 more
2003Cancer Research159 citations
Semantic Scholar
Minimizing long-term tumor burden: the logic for metronomic chemotherapeutic dosing and its antiangiogenic basis.
P. Hahnfeldt, J. Folkman, L. Hlatky
2003Journal of Theoretical Biology147 citations
Semantic Scholar
A convenient extension of the linear-quadratic model to include redistribution and reoxygenation.
D. Brenner, L. Hlatky, P. Hahnfeldt, E. Hall +1 more
1995International Journal of Radiation Oncology, Biology, Physics138 citations Open access
Semantic Scholar
Migration rules: tumours are conglomerates of self-metastases
H. Enderling, L. Hlatky, P. Hahnfeldt
2009British Journal of Cancer136 citations Open access
Semantic Scholar
The Tumor Growth Paradox and Immune System-Mediated Selection for Cancer Stem Cells
T. Hillen, H. Enderling, P. Hahnfeldt
2013Bulletin of Mathematical Biology114 citations Open access
Semantic Scholar
A new view of radiation-induced cancer: integrating short- and long-term processes. Part II: second cancer risk estimation
I. Shuryak, P. Hahnfeldt, L. Hlatky, R. Sachs +1 more
2009Radiation and Environmental Biophysics105 citations Open access
Semantic Scholar
Chromosomes are predominantly located randomly with respect to each other in interphase human cells
M. Cornforth, K. M. Greulich-Bode, B. Loucas, J. Arsuaga +7 more
2002Journal of Cell Biology104 citations Open access
Semantic Scholar
The emerging "hallmarks" of metabolic reprogramming and immune evasion: distinct or linked?
I. Kareva, P. Hahnfeldt
2013Cancer Research101 citations Open access
Semantic Scholar
Quantitative Modeling of Tumor Dynamics and Radiotherapy
H. Enderling, M. Chaplain, P. Hahnfeldt
2010Acta Biotheoretica89 citations
Semantic Scholar
A new view of radiation-induced cancer: integrating short- and long-term processes. Part I: Approach
I. Shuryak, P. Hahnfeldt, L. Hlatky, R. Sachs +1 more
2009Radiation and Environmental Biophysics86 citations Open access
Semantic Scholar
Proton Irradiation Suppresses Angiogenic Genes and Impairs Cell Invasion and Tumor Growth
S. Girdhani, Clare Lamont, P. Hahnfeldt, A. Abdollahi +1 more
2012Radiation Research85 citations
Semantic Scholar
Heterogeneity of androgen receptor content in advanced prostate cancer.
C. Magi-Galluzzi, XiaoWen Xu, L. Hlatky, P. Hahnfeldt +4 more
1997Modern Pathology82 citations
Semantic Scholar
Evolution and Phenotypic Selection of Cancer Stem Cells
J. Poleszczuk, P. Hahnfeldt, H. Enderling
2015PLoS Comput. Biol.71 citations Open access
Semantic Scholar
A Multi-Compartment Mathematical Model of Cancer Stem Cell Driven Tumor Growth Dynamics
Suzanne L. Weekes, B. Barker, Sarah J. Bober, Karina T. Cisneros +5 more
2014Bulletin of Mathematical Biology68 citations Open access
Semantic Scholar
The Importance of Spatial Distribution of Stemness and Proliferation State in Determining Tumor Radioresponse
H. Enderling, D. Park, L. Hlatky, P. Hahnfeldt
200967 citations Open access
Semantic Scholar
Radiation-induced leukemia at doses relevant to radiation therapy: modeling mechanisms and estimating risks.
I. Shuryak, R. Sachs, L. Hlatky, M. Little +2 more
2006Journal of the National Cancer Institute67 citations Open access
Semantic Scholar
Cancer stem cells in solid tumors: is 'evading apoptosis' a hallmark of cancer?
H. Enderling, P. Hahnfeldt
2011Progress in Biophysics and Molecular Biology64 citations
Semantic Scholar
Mathematical models of immune-induced cancer dormancy and the emergence of immune evasion
K. Wilkie, P. Hahnfeldt
2013Interface Focus62 citations Open access
Semantic Scholar
Cancer Stem Cells: A Minor Cancer Subpopulation that Redefines Global Cancer Features
H. Enderling, L. Hlatky, P. Hahnfeldt
2013Frontiers in Oncology62 citations Open access
Semantic Scholar
Integrated Systems and Technologies : Mathematical Oncology Tumor – Immune Dynamics Regulated in the Microenvironment Inform the Transient Nature of Immune-Induced Tumor Dormancy
K. Wilkie, P. Hahnfeldt
201362 citations
Semantic Scholar
Second cancers after fractionated radiotherapy: stochastic population dynamics effects.
R. Sachs, I. Shuryak, D. Brenner, H. Fakir +2 more
2007Journal of Theoretical Biology57 citations Open access
Semantic Scholar
Maximum tolerated dose versus metronomic scheduling in the treatment of metastatic cancers.
S. Benzekry, P. Hahnfeldt
2013Journal of Theoretical Biology56 citations Open access
Semantic Scholar
Intra-arm and interarm chromosome intrachanges: tools for probing the geometry and dynamics of chromatin.
Rainer K. Sachs, David J. Brenner, Allen M. Chen, P. Hahnfeldt +1 more
1997Radiation Research55 citations
Semantic Scholar
Non-stem cancer cell kinetics modulate solid tumor progression
Charles I. Morton, L. Hlatky, P. Hahnfeldt, H. Enderling
2011Theoretical Biology and Medical Modelling54 citations Open access
Semantic Scholar
Modeling the Dichotomy of the Immune Response to Cancer: Cytotoxic Effects and Tumor-Promoting Inflammation
K. Wilkie, P. Hahnfeldt
2013Bulletin of Mathematical Biology50 citations Open access
Semantic Scholar
Evaluating biomarkers to model cancer risk post cosmic ray exposure
D. Sridhara, A. Asaithamby, S. Blattnig, S. Costes +16 more
2016Life sciences and space research49 citations Open access
Semantic Scholar
Clustering of radiation-produced breaks along chromosomes: modelling the effects on chromosome aberrations.
R. Sachs, A.-M. Chen, P. Simpson, L. Hlatky +2 more
1999International Journal of Radiation Biology39 citations
Semantic Scholar
Mathematical modeling of tumor-tumor distant interactions supports a systemic control of tumor growth
S. Benzekry, Clare Lamont, D. Barbolosi, L. Hlatky +1 more
2017bioRxiv38 citations Open access
Semantic Scholar
Systems biology and its potential role in radiobiology
L. Feinendegen, P. Hahnfeldt, E. Schadt, M. Stumpf +1 more
2008Radiation and Environmental Biophysics37 citations
Semantic Scholar
Therapeutic Implications from Sensitivity Analysis of Tumor Angiogenesis Models
J. Poleszczuk, P. Hahnfeldt, H. Enderling
2015PLoS ONE36 citations Open access
Semantic Scholar
Immunoediting: evidence of the multifaceted role of the immune system in self-metastatic tumor growth
H. Enderling, L. Hlatky, P. Hahnfeldt
2012Theoretical Biology and Medical Modelling36 citations Open access
Semantic Scholar
Random breakage and reunion chromosome aberration formation model; an interaction–distance version based on chromatin geometry
Rainer K. Sachs, D. Levy, Allen M. Chen, P. Simpson +4 more
2000International Journal of Radiation Biology36 citations
Semantic Scholar
Host Age Is a Systemic Regulator of Gene Expression Impacting Cancer Progression
A. Beheshti, S. Benzekry, J. Mcdonald, Li-Li Ma +3 more
2015Cancer Research35 citations Open access
Semantic Scholar
Chromosome spatial clustering inferred from radiogenic aberrations
J. Arsuaga, K. M. Greulich-Bode, Mariel Vázquez, M. Brückner +4 more
2004International Journal of Radiation Biology35 citations Open access
Semantic Scholar
Chromosome aberrations produced by radiation: the relationship between excess acentric fragments and dicentrics.
P. Hahnfeldt, L. Hlatky, David J. Brenner, Rainer K. Sachs
1995Radiation Research33 citations
Semantic Scholar
Global Dormancy of Metastases Due to Systemic Inhibition of Angiogenesis
S. Benzekry, A. Gandolfi, P. Hahnfeldt
2014PLoS ONE32 citations Open access
Semantic Scholar
Cell resensitization during protracted dosing of heterogeneous cell populations.
P. Hahnfeldt, L. Hlatky
1998Radiation Research32 citations
Semantic Scholar
Interpretation of inverse dose-rate effects for mutagenesis by sparsely ionizing radiation.
D. J. Brenner, P. Hahnfeldt, S. Amundson, R. Sachs
1996International Journal of Radiation Biology31 citations
Semantic Scholar

Frequent co-authors

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L. Hlatky×32
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L. Hlatky — researcher profile on SciRah
H. Enderling×12
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R. Sachs×9
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J. Folkman×7
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A. Abdollahi×5

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Rainer K. Sachs — researcher profile on SciRah

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