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L. Poole · SciRah

Researcher profile · Semantic Scholar

L. Poole

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L. Poole — researcher profile on SciRah

h-index: 54
Works: 196
Citations: 15K

Most-cited papers

The Basics of Thiols and Cysteines in Redox Biology and Chemistry
L. Poole
2014Free Radical Biology & Medicine909 citations Open access
Semantic Scholar
Peroxiredoxins: Guardians Against Oxidative Stress and Modulators of Peroxide Signaling
A. Perkins, K. Nelson, D. Parsonage, L. Poole +1 more
2015TIBS -Trends in Biochemical Sciences. Regular ed565 citations Open access
Semantic Scholar
Structure-based Insights into the Catalytic Power and Conformational Dexterity of Peroxiredoxins
A. Hall, K. Nelson, L. Poole, P. A. Karplus
2011Antioxidants and Redox Signaling315 citations Open access
Semantic Scholar
A high throughput drug screen for Entamoeba histolytica identifies a new lead and target
A. Debnath, D. Parsonage, R. Andrade, Chen He +12 more
2012Nature Medicine295 citations Open access
Semantic Scholar
Cysteine Oxidation of Copper transporter SLC31A1/CTR1, drives VEGFR2 signaling and Angiogenesis
Archita Das, D. Ash, A. Fouda, Varadarajan Sudhahar +14 more
2022Nature Cell Biology152 citations Open access
Semantic Scholar
Isoform-specific regulation of Akt by PDGF-induced reactive oxygen species
Revati Wani, Jiang Qian, Leimiao Yin, Erika Bechtold +5 more
2011Proceedings of the National Academy of Sciences of the United States of America133 citations Open access
Semantic Scholar
Oxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signaling in Aging Chondrocytes*
J. Collins, Scott T. Wood, K. Nelson, Meredith A. Rowe +5 more
2016Journal of Biological Chemistry125 citations Open access
Semantic Scholar
Overview of Peroxiredoxins in oxidant defense and redox regulation
L. Poole, A. Hall, K. Nelson
2011Current Protocols in Toxicology102 citations Open access
Semantic Scholar
Chemical approaches to detect and analyze protein sulfenic acids
C. Furdui, L. Poole
2013Mass spectrometry reviews (Print)86 citations Open access
Semantic Scholar
Peroxiredoxins in Parasites
Michael C. Gretes, L. Poole, P. A. Karplus
2012Antioxidants and Redox Signaling83 citations Open access
Semantic Scholar
Differential Kinetics of Two-Cysteine Peroxiredoxin Disulfide Formation Reveal a Novel Model for Peroxide Sensing
Stephanie Portillo-Ledesma, L. Randall, D. Parsonage, Joaquín Dalla-Rizza +4 more
2018Biochemistry81 citations Open access
Semantic Scholar
X-ray structures of thioredoxin and thioredoxin reductase from Entamoeba histolytica and prevailing hypothesis of the mechanism of Auranofin action
D. Parsonage, Fang Sheng, K. Hirata, A. Debnath +5 more
2016Journal of Structural Biology70 citations Open access
Semantic Scholar
Distribution and Features of the Six Classes of Peroxiredoxins
L. Poole, K. Nelson
2016Molecules and Cells65 citations Open access
Semantic Scholar
A simple and effective strategy for labeling cysteine sulfenic acid in proteins by utilization of β-ketoesters as cleavable probes
J. Qian, Revati Wani, Chananat Klomsiri, L. Poole +2 more
2012Chemical Communications63 citations Open access
Semantic Scholar
Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins
Jesalyn A. Bolduc, K. Nelson, Alexina C. Haynes, Jing-Yun Lee +7 more
2018Journal of Biological Chemistry61 citations Open access
Semantic Scholar
A New Family of Membrane Electron Transporters and Its Substrates, Including a New Cell Envelope Peroxiredoxin, Reveal a Broadened Reductive Capacity of the Oxidative Bacterial Cell Envelope
Seung-Hyun Cho, D. Parsonage, C. Thurston, R. Dutton +3 more
2012mBio61 citations Open access
Semantic Scholar
Peroxiredoxins in Cancer and Response to Radiation Therapies
T. Forshaw, Reetta Holmila, K. Nelson, Joshua E. Lewis +5 more
2019Antioxidants53 citations Open access
Semantic Scholar
Sirtuin 6 (SIRT6) regulates redox homeostasis and signaling events in human articular chondrocytes
J. Collins, M. Kapustina, Jesalyn A. Bolduc, J. F. W. Pike +8 more
2021Free Radical Biology & Medicine49 citations Open access
Semantic Scholar
The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch
Christopher H Mauney, Leann C. Rogers, R. Harris, L. Daniel +6 more
2017Antioxidants and Redox Signaling49 citations Open access
Semantic Scholar
Nitration Transforms a Sensitive Peroxiredoxin 2 into a More Active and Robust Peroxidase*
L. Randall, Bruno Manta, Martín Hugo, M. Gil +4 more
2014Journal of Biological Chemistry46 citations Open access
Semantic Scholar
Kinetic and Thermodynamic Features Reveal That E. coli BCP Is an Unusually Versatile Peroxiredoxin
Stacy A. Reeves, D. Parsonage, K. Nelson, L. Poole
2011Biochemistry46 citations Open access
Semantic Scholar
Peroxiredoxin Catalysis at Atomic Resolution
A. Perkins, D. Parsonage, K. Nelson, O. Maduka Ogba +3 more
2016Structure40 citations Open access
Semantic Scholar
Chaperone activation and client binding of a 2-cysteine peroxiredoxin
F. Teixeira, E. Tse, H. Castro, Karl A. T. Makepeace +7 more
2019Nature Communications39 citations Open access
Semantic Scholar
H2O2 oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes
K. Nelson, Jesalyn A. Bolduc, Han-Zhi Wu, J. Collins +8 more
2018Journal of Biological Chemistry37 citations Open access
Semantic Scholar
The Oxidative State of Cysteine Thiol 144 Regulates the SIRT6 Glucose Homeostat
D. Long, Han-Zhi Wu, Allen W. Tsang, L. Poole +5 more
2017Scientific Reports37 citations Open access
Semantic Scholar
Endogenous, Regulatory Cysteine Sulfenylation of ERK Kinases in Response to Proliferative Signals
Jeremiah D. Keyes, D. Parsonage, R. Yammani, Leann C. Rogers +4 more
2017Free Radical Biology & Medicine31 citations Open access
Semantic Scholar
Mitigation of doxorubicin-induced cardiotoxicity with an H2O2-Activated, H2S-Donating hybrid prodrug
Qi-Wei Hu, R. Yammani, Heather Brown-Harding, D. Soto-Pantoja +2 more
2022Redox Biology26 citations Open access
Semantic Scholar
Introduction: What we do and do not know regarding redox processes of thiols in signaling pathways
L. Poole, C. Schöneich
2015Free Radical Biology & Medicine25 citations Open access
Semantic Scholar
NOX4 and Poldip2 induce F-actin oxidation and promote its interaction with vinculin during integrin-mediated cell adhesion
S. Vukelic, Qian Xu, B. Seidel-Rogol, E. Faidley +7 more
2018Arteriosclerosis, Thrombosis and Vascular Biology24 citations Open access
Semantic Scholar
An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins
Angela F. Harper, Janelle B. Leuthaeuser, P. Babbitt, J. Morris +3 more
2017PLoS Comput. Biol.21 citations Open access
Semantic Scholar
d-Alanine Modification of a Protease-Susceptible Outer Membrane Component by the Bordetella pertussis dra Locus Promotes Resistance to Antimicrobial Peptides and Polymorphonuclear Leukocyte-Mediated Killing
N. Taneja, Tridib Ganguly, L. Bakaletz, K. Nelson +3 more
2013Journal of Bacteriology21 citations Open access
Semantic Scholar
Peroxiredoxins as Molecular Triage Agents, Sacrificing Themselves to Enhance Cell Survival During a Peroxide Attack
P. Karplus, L. Poole
2012Molecules and Cells20 citations Open access
Semantic Scholar
Glutathionylation of pyruvate dehydrogenase complex E2 and inflammatory cytokine production during acute inflammation are magnified by mitochondrial oxidative stress
D. Long, Charles E. McCall, L. Poole
2023Redox Biology19 citations Open access
Semantic Scholar
Structural changes upon peroxynitrite-mediated nitration of peroxiredoxin 2; nitrated Prx2 resembles its disulfide-oxidized form
L. Randall, Bruno Manta, K. Nelson, Javier Santos +2 more
2015Archives of Biochemistry and Biophysics19 citations Open access
Semantic Scholar
Structural and Electrostatic Asymmetry at the Active Site in Typical and Atypical Peroxiredoxin Dimers
Freddie R. Salsbury, Ye Yuan, M. Knaggs, L. Poole +1 more
2012Journal of Physical Chemistry B18 citations Open access
Semantic Scholar
Oncogenic KRAS G12C: Kinetic and redox characterization of covalent inhibition
Minh V. Huynh, D. Parsonage, T. Forshaw, V. R. Chirasani +6 more
2022Journal of Biological Chemistry17 citations Open access
Semantic Scholar
SVM-SulfoSite: A support vector machine based predictor for sulfenylation sites
Hussam J. AL-barakati, Evan W. McConnell, L. Hicks, L. Poole +2 more
2018Scientific Reports17 citations Open access
Semantic Scholar
Peroxiredoxin II Regulates Effector and Secondary Memory CD8+ T Cell Responses
Ryan D. Michalek, K. Crump, Ashley E. Weant, E. Hiltbold +5 more
2012Journal of Virology16 citations Open access
Semantic Scholar
Acyl-lipid desaturases and Vipp1 cooperate in cyanobacteria to produce novel omega-3 PUFA-containing glycolipids
L. Poole, D. Parsonage, S. Sergeant, Leslie R. Miller +3 more
2020bioRxiv15 citations Open access
Semantic Scholar
Nuclear-localized, iron-bound superoxide dismutase-2 antagonizes epithelial lineage programs to promote stemness of breast cancer cells via a histone demethylase activity
Diego R. Coelho, Flavio R. Palma, Verônica Paviani, Chenxia He +8 more
2022Proceedings of the National Academy of Sciences of the United States of America14 citations Open access
Semantic Scholar
Unraveling the effects of peroxiredoxin 2 nitration; role of C-terminal tyrosine 193
L. Randall, Joaquín Dalla-Rizza, D. Parsonage, Javier Santos +4 more
2019Free Radical Biology & Medicine14 citations Open access
Semantic Scholar
Hydrogen peroxide-dependent oxidation of ERK2 within its D-recruitment site alters its substrate selection
Anthony E. Postiglione, Laquaundra L. Adams, Ese S. Ekhator, Anuoluwapo E. Odelade +20 more
2023iScience9 citations Open access
Semantic Scholar
Backbone chemical shift assignments for Xanthomonas campestris peroxiredoxin Q in the reduced and oxidized states: a dramatic change in backbone dynamics
G. Buchko, A. Perkins, D. Parsonage, L. Poole +1 more
2015Biomolecular NMR Assignments9 citations Open access
Semantic Scholar
Conformational studies of the robust 2-Cys peroxiredoxin Salmonella typhimurium AhpC by solution phase hydrogen/deuterium (H/D) exchange monitored by electrospray ionization mass spectrometry
Sasidhar N Nirudodhi, D. Parsonage, P. Karplus, L. Poole +1 more
2011International Journal of Mass Spectrometry8 citations Open access
Semantic Scholar
Glutathionylation of Pyruvate Dehydrogenase Complex E2 and Inflammatory Cytokine Production During Acute Inflammation Are Magnified By Mitochondrial Oxidative Stress
D. Long, Charles E. McCall, L. Poole
2023bioRxiv6 citations Open access
Semantic Scholar
Identification of sulfenylation patterns in trophozoite stage Plasmodium falciparum using a non-dimedone based probe
Susanne Schipper, Han-Zhi Wu, C. Furdui, L. Poole +5 more
2021Molecular and biochemical parasitology (Print)6 citations Open access
Semantic Scholar
[18F]Fluoro-DCP, a first generation PET radiotracer for monitoring protein sulfenylation in vivo
K. S. Solingapuram Sai, Xiaofei Chen, Zhe Li, Caigang Zhu +12 more
2021Redox Biology5 citations Open access
Semantic Scholar
Native State Fluctuations in a Peroxiredoxin Active Site Match Motions Needed for Catalysis
Aidan B. Estelle, P. Reardon, S. Pinckney, L. Poole +2 more
2021Structure5 citations
Semantic Scholar
Bioinformatic Analyses of Peroxiredoxins and RF-Prx: A Random Forest-Based Predictor and Classifier for Prxs
Hussam J. AL-barakati, R. Newman, Dukka B. Kc, L. Poole
2022Methods in molecular biology4 citations
Semantic Scholar
Mitochondrial peroxiredoxin from Leishmania infantum after heat stress without unfolding client protein
F. Teixeira, E. Tse, K. A. T. Makepeace, C. Borchers +5 more
20194 citations
Semantic Scholar

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