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A. Bradshaw · SciRah

Researcher profile · Semantic Scholar

A. Bradshaw

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A. Bradshaw — researcher profile on SciRah

h-index: 36
Works: 104
Citations: 4,776

Most-cited papers

Myocardial Stiffness in Patients with Heart Failure and a Preserved Ejection Fraction: Contributions of Collagen and Titin
M. Zile, C. Baicu, J. Ikonomidis, Robert E. Stroud +10 more
2015Circulation641 citations Open access
Semantic Scholar
Cardiac macrophages promote diastolic dysfunction
Maarten Hulsmans, H. Sager, Jason D. Roh, M. Valero-Muñoz +20 more
2018Journal of Experimental Medicine453 citations Open access
Semantic Scholar
SPARC/Osteonectin in Mineralized Tissue
E. Rosset, A. Bradshaw
2016Matrix Biology292 citations Open access
Semantic Scholar
Diverse Biological Functions of the SPARC Family of Proteins
A. Bradshaw
2012International Journal of Biochemistry and Cell Biology269 citations Open access
Semantic Scholar
The role of SPARC in extracellular matrix assembly
A. Bradshaw
2009Journal of cell communication and signaling252 citations Open access
Semantic Scholar
SPARC-null mice display abnormalities in the dermis characterized by decreased collagen fibril diameter and reduced tensile strength.
A. Bradshaw, P. Puolakkainen, J. Dasgupta, J. Davidson +2 more
2003Journal of Investigative Dermatology243 citations Open access
Semantic Scholar
SPARC Regulates Processing of Procollagen I and Collagen Fibrillogenesis in Dermal Fibroblasts*
Tyler J. Rentz, Felicitta Poobalarahi, P. Bornstein, E. Sage +1 more
2007Journal of Biological Chemistry161 citations Open access
Semantic Scholar
Pressure-Overload Induced Alterations in Fibrillar Collagen Content and Myocardial Diastolic Function: Role of SPARC in Post-Synthetic Procollagen Processing
A. Bradshaw, C. Baicu, Tyler J. Rentz, A. V. Van Laer +3 more
2008Circulation134 citations Open access
Semantic Scholar
Lack of host SPARC enhances vascular function and tumor spread in an orthotopic murine model of pancreatic carcinoma
S. Arnold, Lee B. Rivera, Andrew F. Miller, Juliet G. Carbon +7 more
2010Disease Models & Mechanisms116 citations Open access
Semantic Scholar
Cardiac Extracellular Matrix Remodeling: Fibrillar Collagens and Secreted Protein Acidic and Rich in Cysteine (SPARC)
S. Mccurdy, C. Baicu, S. Heymans, A. Bradshaw
2009Journal of Molecular and Cellular Cardiology114 citations Open access
Semantic Scholar
Cellular mechanisms of tissue fibrosis. 2. Contributory pathways leading to myocardial fibrosis: moving beyond collagen expression.
E. Goldsmith, A. Bradshaw, F. Spinale
2013American Journal of Physiology - Cell Physiology105 citations Open access
Semantic Scholar
The regulatory function of SPARC in vascular biology
Lee B. Rivera, A. Bradshaw, R. Brekken
2011Cellular and Molecular Life Sciences101 citations Open access
Semantic Scholar
Myocardial Fibroblast-Matrix Interactions and Potential Therapeutic Targets
E. Goldsmith, A. Bradshaw, M. Zile, F. Spinale
2014Journal of Molecular and Cellular Cardiology99 citations Open access
Semantic Scholar
The Function of SPARC as a Mediator of Fibrosis
J. Trombetta-eSilva, A. Bradshaw
2012Open Rheumatology Journal83 citations Open access
Semantic Scholar
Losartan Slows Pancreatic Tumor Progression and Extends Survival of SPARC-Null Mice by Abrogating Aberrant TGFβ Activation
S. Arnold, Lee B. Rivera, Juliet G. Carbon, Jason E. Toombs +3 more
2012PLoS ONE80 citations Open access
Semantic Scholar
SPARC regulates collagen interaction with cardiac fibroblast cell surfaces.
Brett S. Harris, Yu-Hua Zhang, L. Card, Lee B. Rivera +2 more
2011American Journal of Physiology. Heart and Circulatory Physiology73 citations Open access
Semantic Scholar
Compromised production of extracellular matrix in mice lacking secreted protein, acidic and rich in cysteine (SPARC) leads to a reduced foreign body reaction to implanted biomaterials.
P. Puolakkainen, A. Bradshaw, T. Kyriakides, M. Reed +5 more
2003American Journal of Pathology72 citations Open access
Semantic Scholar
Secreted protein acidic and rich in cysteine facilitates age-related cardiac inflammation and macrophage M1 polarization.
H. Toba, L. E. de Castro Brás, C. Baicu, M. Zile +2 more
2015American Journal of Physiology - Cell Physiology68 citations Open access
Semantic Scholar
Quantification of Protein Expression Changes in the Aging Left Ventricle of Rattus norvegicus
Jennifer E. Grant, A. Bradshaw, J. Schwacke, C. Baicu +2 more
2009Journal of Proteome Research64 citations Open access
Semantic Scholar
Lysyl Oxidase Directly Contributes to Extracellular Matrix Production and Fibrosis in Systemic Sclerosis.
Xinh-Xinh Nguyen, T. Nishimoto, T. Takihara, Logan Mlakar +2 more
2020American Journal of Physiology - Lung cellular and Molecular Physiology63 citations Open access
Semantic Scholar
Cardiac myofibroblasts differentiated in 3D culture exhibit distinct changes in collagen I production, processing, and matrix deposition.
Felicitta Poobalarahi, C. Baicu, A. Bradshaw
2006American Journal of Physiology. Heart and Circulatory Physiology63 citations
Semantic Scholar
Effects of the absence of procollagen C-endopeptidase enhancer-2 on myocardial collagen accumulation in chronic pressure overload.
C. Baicu, Yu-Hua Zhang, A. V. Van Laer, L. Renaud +2 more
2012American Journal of Physiology. Heart and Circulatory Physiology61 citations Open access
Semantic Scholar
Cross your heart? Collagen cross-links in cardiac health and disease
Lily S. Neff, A. Bradshaw
2020Cellular Signalling60 citations Open access
Semantic Scholar
Increased macrophage-derived SPARC precedes collagen deposition in myocardial fibrosis.
L. McDonald, M. Zile, Yu-Hua Zhang, A. V. Van Laer +5 more
2018American Journal of Physiology. Heart and Circulatory Physiology57 citations Open access
Semantic Scholar
β3 Integrin in Cardiac Fibroblast Is Critical for Extracellular Matrix Accumulation during Pressure Overload Hypertrophy in Mouse
S. Balasubramanian, L. Quinones, Harinath Kasiganesan, Yu-Hua Zhang +5 more
2012PLoS ONE57 citations Open access
Semantic Scholar
SPARC/Osteonectin Functions to Maintain Homeostasis of the Collagenous Extracellular Matrix in the Periodontal Ligament
Jessica M Trombetta, A. Bradshaw, Ralph H. Johnson
2010Journal of Histochemistry and Cytochemistry56 citations Open access
Semantic Scholar
Pleiotropic roles of the matricellular protein Sparc in tendon maturation and ageing
R. Gehwolf, Andrea Wagner, C. Lehner, A. Bradshaw +6 more
2016Scientific Reports52 citations Open access
Semantic Scholar
The role of secreted protein acidic and rich in cysteine (SPARC) in cardiac repair and fibrosis: Does expression of SPARC by macrophages influence outcomes?
A. Bradshaw
2016Journal of Molecular and Cellular Cardiology52 citations
Semantic Scholar
The Influence of the Extracellular Matrix in Inflammation: Findings from the SPARC-null mouse
Hannah J Riley, A. Bradshaw
2019The Anatomical Record51 citations Open access
Semantic Scholar
Increased ADAMTS1 mediates SPARC-dependent collagen deposition in the aging myocardium.
H. Toba, L. E. de Castro Brás, C. Baicu, M. Zile +2 more
2016American Journal of Physiology. Endocrinology and Metabolism50 citations Open access
Semantic Scholar
Widespread Expression of β1 Integrins in the Developing Chick Retina: Evidence for a Role in Migration of Retinal Ganglion Cells
G. Cann, A. Bradshaw, D. B. Gervin, A. Hunter +1 more
199649 citations Open access
Semantic Scholar
Age and SPARC Change the Extracellular Matrix Composition of the Left Ventricle
L. E. de Castro Brás, H. Toba, C. Baicu, M. Zile +3 more
2014BioMed Research International45 citations Open access
Semantic Scholar
Functional Analysis of the Matricellular Protein SPARC with Novel Monoclonal Antibodies
Mariya T. Sweetwyne, R. Brekken, Gail A. Workman, A. Bradshaw +4 more
2004Journal of Histochemistry and Cytochemistry45 citations Open access
Semantic Scholar
Lumican Deficiency Results In Cardiomyocyte Hypertrophy With Altered Collagen Assembly
Loren E. Dupuis, Matthew G. Berger, S. Feldman, Lorna Doucette +6 more
2015Journal of Molecular and Cellular Cardiology42 citations Open access
Semantic Scholar
Inactivation of SPARC enhances high-fat diet-induced obesity in mice
J. Nie, A. Bradshaw, A. Delany, E. Sage
2011Connective Tissue Research39 citations
Semantic Scholar
Time course of right ventricular pressure-overload induced myocardial fibrosis: relationship to changes in fibroblast postsynthetic procollagen processing.
C. Baicu, Jiayu Li, Yu-Hua Zhang, Harinath Kasiganesan +3 more
2012American Journal of Physiology. Heart and Circulatory Physiology38 citations Open access
Semantic Scholar
T-cell regulation of fibroblast and cardiac fibrosis
A. Bradshaw, K. DeLeon-Pennell
2020Matrix Biology37 citations Open access
Semantic Scholar
Dasatinib Attenuates Pressure Overload Induced Cardiac Fibrosis in a Murine Transverse Aortic Constriction Model
S. Balasubramanian, Dorea L. Pleasant, Harinath Kasiganesan, L. Quinones +6 more
2015PLoS ONE35 citations Open access
Semantic Scholar
SPARC-thrombospondin-2-double-null Mice Exhibit Enhanced Cutaneous Wound Healing and Increased Fibrovascular Invasion of Subcutaneous Polyvinyl Alcohol Sponges
P. Puolakkainen, A. Bradshaw, R. Brekken, M. Reed +7 more
2005Journal of Histochemistry and Cytochemistry34 citations Open access
Semantic Scholar
SPARC Production by Bone Marrow-Derived Cells Contributes to Myocardial Fibrosis in Pressure-Overload.
Hannah J Riley, R. Kelly, A. V. Van Laer, Lily S. Neff +6 more
2020American Journal of Physiology. Heart and Circulatory Physiology30 citations Open access
Semantic Scholar
LPS Induces Greater Bone and PDL Loss in SPARC-null Mice
J. Trombetta-eSilva, Hong Yu, D. N. Arias, C. Rossa +2 more
2011Journal of dentistry research24 citations Open access
Semantic Scholar
Enhanced angiogenesis characteristic of SPARC‐null mice disappears with age
May J. Reed, A. Bradshaw, M. Shaw, Eman Sadoun +5 more
2005Journal of Cellular Physiology24 citations
Semantic Scholar
Human SY5Y Neuroblastoma Cell Interactions with Laminin Isoforms: Neurite Outgrowth on Laminin-5 Is Mediated by Integrin α3β1
Barbara E. Smith, A. Bradshaw, E. Choi, P. Rouselle +2 more
199624 citations
Semantic Scholar
Left Ventricular Gene Expression in Heart Failure with Preserved Ejection Fraction - Pro-fibrotic and Pro-inflammatory Pathways and Genes
Bo Ye, A. Bradshaw, J. Abrahante, J. Dragon +6 more
2023Circulation: Heart Failure21 citations
Semantic Scholar
Decreased Mechanical Strength and Collagen Content in SPARC-Null Periodontal Ligament is Reversed by Inhibition of Transglutaminase Activity
J. Trombetta-eSilva, Emilie A. Rosset, R. Glenn Hepfer, Gregory J. Wright +3 more
2015Journal of Bone and Mineral Research21 citations Open access
Semantic Scholar
Pressure-Overload Generates a Cardiac-Specific Profile of Inflammatory Mediators.
M. O'Brien, C. Baicu, A. V. Van Laer, Yu-Hua Zhang +4 more
2020American Journal of Physiology. Heart and Circulatory Physiology19 citations Open access
Semantic Scholar
Organized Chaos: Deciphering Immune Cell Heterogeneity’s Role in Inflammation in the Heart
A. Corker, Lily S. Neff, Philip Broughton, A. Bradshaw +1 more
2021Biomolecules17 citations Open access
Semantic Scholar
SPARC and the N-propeptide of collagen I influence fibroblast proliferation and collagen assembly in the periodontal ligament
E. Rosset, J. Trombetta-eSilva, Glenn Hepfer, H. Yao +1 more
2017PLoS ONE16 citations Open access
Semantic Scholar
Widespread expression of beta1 integrins in the developing chick retina: evidence for a role in migration of retinal ganglion cells.
G. Cann, A. Bradshaw, D. B. Gervin, A. Hunter +1 more
1996Developmental Biology16 citations
Semantic Scholar
pGlcNAc Nanofiber Treatment of Cutaneous Wounds Stimulate Increased Tensile Strength and Reduced Scarring via Activation of Akt1
Haley Buff Lindner, L. Felmly, M. Demcheva, A. Seth +4 more
2015PLoS ONE13 citations Open access
Semantic Scholar

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M. Zile×15
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A. V. Van Laer×5

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