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L. De Filippis · SciRah

Researcher profile · Semantic Scholar

L. De Filippis

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L. De Filippis — researcher profile on SciRah

h-index: 24
Works: 52
Citations: 2,002

Most-cited papers

The EphA2 Receptor Drives Self-Renewal and Tumorigenicity in Stem-Like Tumor-Propagating Cells from Human Glioblastomas
E. Binda, A. Visioli, Fabrizio Giani, G. Lamorte +14 more
2012Cancer Cell217 citations Open access
Semantic Scholar
Mild Hypoxia Enhances Proliferation and Multipotency of Human Neural Stem Cells
G. Santilli, G. Lamorte, L. Carlessi, D. Ferrari +5 more
2010PLoS ONE202 citations Open access
Semantic Scholar
Emx2 regulates the proliferation of stem cells of the adult mammalian central nervous system.
R. Galli, R. Fiocco, L. De Filippis, L. Muzio +6 more
2002Development151 citations
Semantic Scholar
The proliferative capacity of the subventricular zone is maintained in the parkinsonian brain.
S. A. van den Berge, M. V. van Strien, J. Korecka, A. Dijkstra +8 more
2011Brain : a journal of neurology123 citations Open access
Semantic Scholar
Hypoxia in the regulation of neural stem cells
L. De Filippis, D. Delia
2011Cellular and Molecular Life Sciences109 citations
Semantic Scholar
A Novel, Immortal, and Multipotent Human Neural Stem Cell Line Generating Functional Neurons and Oligodendrocytes
L. De Filippis, G. Lamorte, E. Snyder, A. Malgaroli +1 more
2007Stem Cells96 citations Open access
Semantic Scholar
GFAPδ in radial glia and subventricular zone progenitors in the developing human cortex
J. Middeldorp, K. Boer, J. Sluijs, L. De Filippis +5 more
2010Development91 citations Open access
Semantic Scholar
Neural Stem Cells in the Adult Nervous System
Daniele Bottai, R. Fiocco, F. Gelain, L. De Filippis +3 more
2003Journal of Hematotherapy & Stem Cell Research82 citations
Semantic Scholar
DNA-damage response, survival and differentiation in vitro of a human neural stem cell line in relation to ATM expression
L. Carlessi, L. De Filippis, D. Lecis, A. Vescovi +1 more
2009Cell Death and Differentiation67 citations Open access
Semantic Scholar
Long-Term Survival of Human Neural Stem Cells in the Ischemic Rat Brain upon Transient Immunosuppression
Laura Rota Nodari, D. Ferrari, Fabrizio Giani, M. Bossi +5 more
2010PLoS ONE62 citations Open access
Semantic Scholar
Histone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament network
R. Kanski, M. Sneeboer, E. V. van Bodegraven, J. Sluijs +9 more
2014Journal of Cell Science59 citations Open access
Semantic Scholar
Immortalization of Human Neural Stem Cells with the c-Myc Mutant T58A
L. De Filippis, D. Ferrari, Laura Rota Nodari, B. Amati +2 more
2008PLoS ONE53 citations Open access
Semantic Scholar
Chronic exposure of astrocytes to interferon-α reveals molecular changes related to Aicardi-Goutieres syndrome.
E. Cuadrado, Machiel H. Jansen, J. Anink, L. De Filippis +5 more
2013Brain : a journal of neurology52 citations Open access
Semantic Scholar
Concise Review: Self‐Renewal in the Central Nervous System: Neural Stem Cells from Embryo to Adult
L. De Filippis, E. Binda
2012Stem Cells Translational Medicine49 citations Open access
Semantic Scholar
Toll-like receptor 4 modulation influences human neural stem cell proliferation and differentiation
C. Grasselli, D. Ferrari, C. Zalfa, Matias Soncini +8 more
2018Cell Death and Disease47 citations Open access
Semantic Scholar
Phenotypic Variation in Aicardi–Goutières Syndrome Explained by Cell-Specific IFN-Stimulated Gene Response and Cytokine Release
E. Cuadrado, I. Michailidou, E. V. van Bodegraven, Machiel H. Jansen +7 more
2015Journal of Immunology47 citations Open access
Semantic Scholar
Isolation of neural stem cells from neural tissues using the neurosphere technique.
D. Ferrari, E. Binda, L. De Filippis, A. Vescovi
2010Current protocols in stem cell biology46 citations
Semantic Scholar
Combination Drug Therapy for the Management of Chronic Neuropathic Pain
S. Boccella, L. De Filippis, Cristina Giorgio, L. Brandolini +11 more
2023Biomolecules42 citations Open access
Semantic Scholar
Transplantation of clinical-grade human neural stem cells reduces neuroinflammation, prolongs survival and delays disease progression in the SOD1 rats
C. Zalfa, Laura Rota Nodari, Elena Vacchi, M. Gelati +17 more
2019Cell Death and Disease38 citations Open access
Semantic Scholar
Ethanol-mediated activation of the NLRP3 inflammasome in iPS cells and iPS cells-derived neural progenitor cells
L. De Filippis, Apoorva Halikere, Heather McGowan, J. Moore +3 more
2016Molecular Brain37 citations Open access
Semantic Scholar
Glucose transportation in the brain and its impairment in Huntington disease: one more shade of the energetic metabolism failure?
V. Morea, Eris Bidollari, G. Colotti, A. Fiorillo +4 more
2017Amino Acids33 citations
Semantic Scholar
Glial degeneration with oxidative damage drives neuronal demise in MPSII disease
C. Zalfa, C. Verpelli, F. D'Avanzo, R. Tomanin +7 more
2016Cell Death and Disease33 citations Open access
Semantic Scholar
Murine neural stem cells model Hunter disease in vitro: glial cell-mediated neurodegeneration as a possible mechanism involved
E. Poli, C. Zalfa, F. D'Avanzo, R. Tomanin +9 more
2013Cell Death and Disease30 citations Open access
Semantic Scholar
Emx 2 regulates the proliferation of stem cells of the adult mammalian central nervous system
R. Galli, R. Fiocco, L. De Filippis, L. Muzio +6 more
200224 citations
Semantic Scholar
Neural Stem Cells and Human Induced Pluripotent Stem Cells to Model Rare CNS Diseases.
L. De Filippis, C. Zalfa, D. Ferrari
2018CNS and Neurological Disorders - Drug Targets23 citations
Semantic Scholar
ATM-deficient human neural stem cells as an in vitro model system to study neurodegeneration
L. Carlessi, Elena Fusar Poli, L. De Filippis, D. Delia
2013DNA Repair22 citations Open access
Semantic Scholar
μNeurocircuitry: Establishing in vitro models of neurocircuits with human neurons
Joseph A Fantuzzo, L. De Filippis, Heather McGowan, Nan Yang +7 more
2017Technology21 citations Open access
Semantic Scholar
Differential pathotropism of non-immortalized and immortalized human neural stem cell lines in a focal demyelination model
D. Ferrari, C. Zalfa, Laura Rota Nodari, M. Gelati +4 more
2011Cellular and Molecular Life Sciences21 citations Open access
Semantic Scholar
Neural Stem Cells from Shank3-ko Mouse Model Autism Spectrum Disorders
C. Grasselli, A. Carbone, Patrizio Panelli, V. Giambra +3 more
2019Molecular Neurobiology20 citations
Semantic Scholar
Differentiated human neural stem cells: a new ex vivo model to study HHV-6 infection of the central nervous system.
L. De Filippis, C. Foglieni, S. Silva, A. Vescovi +2 more
2006Journal of Clinical Virology18 citations
Semantic Scholar
The adult human subventricular zone: partial ependymal coverage and proliferative capacity of cerebrospinal fluid
S. D. de Sonnaville, M. V. van Strien, J. Middeldorp, J. Sluijs +13 more
2020Brain Communications16 citations Open access
Semantic Scholar
Neuronal Cells Display Distinct Stability Controls of Alternative Polyadenylation mRNA Isoforms, Long Non-Coding RNAs, and Mitochondrial RNAs
A. Guvenek, Jihae Shin, L. De Filippis, Dinghai Zheng +3 more
2022Frontiers in Genetics11 citations Open access
Semantic Scholar
Neural stem cell-mediated therapy for rare brain diseases: perspectives in the near future for LSDs and MNDs.
L. De Filippis
2011Histology and Histopathology11 citations
Semantic Scholar
Histone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament network
Regina Kanski, Marjolein A. M. Sneeboer, E. V. van Bodegraven, J. Sluijs +9 more
2014Development10 citations Open access
Semantic Scholar
Neural stem cell-mediated therapy for rare brain diseases : perspectives in the near future for LSDs and MNDs
L. De Filippis
9 citations
Semantic Scholar
Clinical-grade intranasal NGF fuels neurological and metabolic functions of Mecp2-deficient mice
D. Pozzer, M. Indrigo, M. Breccia, E. Florio +10 more
2024Brain : a journal of neurology7 citations Open access
Semantic Scholar
The Role of TLR4 in Neural Stem Cells–Mediated Neurogenesis and Neuroinflammation
L. De Filippis, F. Peri
20206 citations
Semantic Scholar
The therapeutic potential of an allosteric non‐competitive CXCR1/2 antagonist for diabetic nephropathy
C. Grasselli, S. Bombelli, V. D'Esposito, M. F. Di Tolla +11 more
2023Diabetes/Metabolism Research Reviews5 citations Open access
Semantic Scholar
Intranasal administration of recombinant human BDNF as a potential therapy for some primary headaches
R. Greco, M. Francavilla, Sara Facchetti, C. Demartini +8 more
2024The Journal of Headache and Pain3 citations Open access
Semantic Scholar
Reparixin as a Potential Antiepileptogenic Agent: Modulation of the CXCL1–CXCR1/2 Axis and Seizure Activity in a Kindling Rat Model of Temporal Lobe Epilepsy
N. Çarçak, Nursima Mutlu, Elif Tuğçe Erdeve, T. Turan +10 more
2025International Journal of Molecular Sciences2 citations Open access
Semantic Scholar
Ladarixin Potential over the Effects of IL-8 and of Serum from Patients with Abdominal Aortic Aneurysm on Human Aortic Cells
L. Spartano, M. Lombardi, V. Ardita, R. Chiesa +5 more
2025Cells2 citations Open access
Semantic Scholar
Modulation of MMP9 and CXCR2/CXCL1/IL-8 axis in human abdominal aortic aneurysm tissues by ladarixin.
M. Lombardi, L. Spartano, S. Nicolò, V. Ardita +6 more
2024Cardiovascular Research2 citations
Semantic Scholar
GFAP Delta as Divergent Marker of Human Glial Progenitors
C. Zalfa, C. Grasselli, G. Santilli, D. Ferrari +3 more
20182 citations Open access
Semantic Scholar
Exploring the Correlation Between NLRP3 Activation and Endothelial-to-Mesenchymal Transition in the Heart of a Murine Model of Systemic Sclerosis
Natasha Irrera, L. De Filippis, Davide Labellarte, J. Freni +5 more
2025Cells1 citations Open access
Semantic Scholar
Low Immunogenic Potential of Human Neural Stem Cells
L. De Filippis, L. Nodari, M. Gelati
20121 citations Open access
Semantic Scholar
73: Human herpesvirus 6 and multiple sclerosis: detection by quantitative real-time PCR and role of complement-mediated damage secondary to CD46 inactivation
P. Lusso, L. De Filippis, C. Foglieni, A. Vescovi +4 more
20061 citations
Semantic Scholar
Inflammatory networks between adipose tissue, liver and pancreatic islets in type 2 diabetes
M. Farrim, Diogo Silva, Andreia Gomes, L. De Filippis +6 more
2026Human Genomics0 citations Open access
Semantic Scholar
15 Low Immunogenic Potential of Human Neural Stem Cells
L. De Filippis, L. Nodari, M. Gelati
20170 citations
Semantic Scholar
Ethanol-mediated activation of the NLRP3 inflammasome in iPS cells and iPS cells-derived neural progenitor cells
L. De Filippis, Apoorva Halikere, Heather McGowan, J. Moore +3 more
2016Molecular Brain0 citations Open access
Semantic Scholar
Harness the power of endogenous neural stem cells by biomaterials to treat spinal cord injury
L. De Filippis, T. Südhof, Z. Pang
2015Science China Life Sciences0 citations Open access
Semantic Scholar

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