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J. Hayek · SciRah

Researcher profile · Semantic Scholar

J. Hayek

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J. Hayek — researcher profile on SciRah

h-index: 37
Works: 138
Citations: 4,577

Most-cited papers

New evidences on the altered gut microbiota in autism spectrum disorders
F. Strati, D. Cavalieri, D. Albanese, C. De Felice +7 more
2017Microbiome914 citations Open access
Semantic Scholar
Altered gut microbiota in Rett syndrome
F. Strati, D. Cavalieri, D. Albanese, C. De Felice +10 more
2016Microbiome128 citations Open access
Semantic Scholar
Cholesterol Metabolism Is Altered in Rett Syndrome: A Study on Plasma and Primary Cultured Fibroblasts Derived from Patients
M. Segatto, Laura Trapani, Ilenia Di Tunno, C. Sticozzi +3 more
2014PLoS ONE74 citations Open access
Semantic Scholar
Cytokine Dysregulation in MECP2- and CDKL5-Related Rett Syndrome: Relationships with Aberrant Redox Homeostasis, Inflammation, and ω-3 PUFAs
S. Leoncini, C. De Felice, C. Signorini, G. Zollo +7 more
2015Oxidative Medicine and Cellular Longevity73 citations Open access
Semantic Scholar
Cytokines profile and peripheral blood mononuclear cells morphology in Rett and autistic patients.
A. Pecorelli, F. Cervellati, G. Belmonte, G. Montagner +4 more
2016Cytokine66 citations Open access
Semantic Scholar
Epilepsy in Rett syndrome—Lessons from the Rett networked database
A. Nissenkorn, Rachel S. Levy-Drummer, Ori Bondi, A. Renieri +22 more
2015Epilepsia56 citations Open access
Semantic Scholar
Impaired enzymatic defensive activity, mitochondrial dysfunction and proteasome activation are involved in RTT cell oxidative damage.
C. Cervellati, C. Sticozzi, Arianna Romani, G. Belmonte +10 more
2015Biochimica et Biophysica Acta55 citations Open access
Semantic Scholar
OxInflammation in Rett syndrome.
A. Pecorelli, C. Cervellati, J. Hayek, G. Valacchi
2016International Journal of Biochemistry and Cell Biology54 citations Open access
Semantic Scholar
Compromised immune/inflammatory responses in Rett syndrome.
A. Pecorelli, C. Cervellati, V. Cordone, J. Hayek +1 more
2020Free Radical Biology & Medicine47 citations Open access
Semantic Scholar
Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome
D. Sbardella, G. Tundo, L. Campagnolo, G. Valacchi +12 more
2017Scientific Reports46 citations Open access
Semantic Scholar
Expression and oxidative modifications of plasma proteins in autism spectrum disorders: Interplay between inflammatory response and lipid peroxidation
Alessio Cortelazzo, C. De Felice, R. Guerranti, C. Signorini +7 more
2016PROTEOMICS - Clinical Applications44 citations Open access
Semantic Scholar
Visual impairment in FOXG1-mutated individuals and mice.
E. Boggio, L. Pancrazi, M. Gennaro, C. L. Rizzo +12 more
2016Neuroscience43 citations Open access
Semantic Scholar
Alterations of mitochondrial bioenergetics, dynamics, and morphology support the theory of oxidative damage involvement in autism spectrum disorder
A. Pecorelli, F. Ferrara, Nicolo’ Messano, V. Cordone +6 more
2020The FASEB Journal42 citations
Semantic Scholar
Coffin-Siris and Nicolaides-Baraitser syndromes are a common well recognizable cause of intellectual disability.
F. Mari, A. Marozza, M. Mencarelli, Caterina Lo Rizzo +22 more
2015Brain & development (Tokyo. 1979)42 citations Open access
Semantic Scholar
Analysis of the Phenotypes in the Rett Networked Database
E. Frullanti, F. T. Papa, Elisa Grillo, A. Clarke +28 more
2019International Journal of Genomics41 citations Open access
Semantic Scholar
Altered inflammasome machinery as a key player in the perpetuation of Rett syndrome oxinflammation
A. Pecorelli, V. Cordone, Nicolo’ Messano, Chang-Qing Zhang +4 more
2019Redox Biology39 citations Open access
Semantic Scholar
13-HODE, 9-HODE and ALOX15 as potential players in Rett syndrome OxInflammation.
A. Pecorelli, C. Cervellati, V. Cordone, F. Amicarelli +2 more
2019Free Radical Biology & Medicine34 citations Open access
Semantic Scholar
Relevance of 4‐F4t‐neuroprostane and 10‐F4t‐neuroprostane to neurological diseases
C. Signorini, C. De Felice, T. Durand, J. Galano +9 more
2018Free Radical Biology & Medicine34 citations Open access
Semantic Scholar
4-hydroxynonenal protein adducts: Key mediator in Rett syndrome oxinflammation.
G. Valacchi, A. Pecorelli, C. Cervellati, J. Hayek
2017Free Radical Biology & Medicine33 citations Open access
Semantic Scholar
Rett syndrome: An autoimmune disease?
C. De Felice, S. Leoncini, C. Signorini, Alessio Cortelazzo +5 more
2016Autoimmunity Reviews33 citations
Semantic Scholar
Impaired mitochondrial quality control in Rett Syndrome.
I. Crivellari, A. Pecorelli, V. Cordone, S. Marchi +4 more
2021Archives of Biochemistry and Biophysics29 citations Open access
Semantic Scholar
MECP2 Duplication Syndrome: Evidence of Enhanced Oxidative Stress. A Comparison with Rett Syndrome
C. Signorini, C. De Felice, S. Leoncini, R. Møller +9 more
2016PLoS ONE29 citations Open access
Semantic Scholar
Proteomic profiling reveals mitochondrial alterations in Rett syndrome.
Vittoria Cicaloni, A. Pecorelli, Laura Tinti, M. Rossi +8 more
2020Free Radical Biology & Medicine28 citations Open access
Semantic Scholar
Proteomic analysis of 4-hydroxynonenal and nitrotyrosine modified proteins in RTT fibroblasts.
A. Pecorelli, C. Cervellati, Alessio Cortelazzo, F. Cervellati +8 more
2016International Journal of Biochemistry and Cell Biology24 citations
Semantic Scholar
Persistent Unresolved Inflammation in the Mecp2-308 Female Mutated Mouse Model of Rett Syndrome
Alessio Cortelazzo, C. De Felice, B. De Filippis, L. Ricceri +9 more
2017Mediators of Inflammation22 citations Open access
Semantic Scholar
Isoprostanoids in Clinical and Experimental Neurological Disease Models
C. Signorini, C. De Felice, J. Galano, C. Oger +6 more
2018Antioxidants20 citations Open access
Semantic Scholar
Lactonase Activity and Lipoprotein-Phospholipase A2 as Possible Novel Serum Biomarkers for the Differential Diagnosis of Autism Spectrum Disorders and Rett Syndrome: Results from a Pilot Study
J. Hayek, C. Cervellati, I. Crivellari, A. Pecorelli +1 more
2017Oxidative Medicine and Cellular Longevity20 citations Open access
Semantic Scholar
Proteomic analysis of the Rett syndrome experimental model mecp2Q63X mutant zebrafish.
Alessio Cortelazzo, T. Pietri, C. De Felice, S. Leoncini +6 more
2017Journal of Proteomics19 citations Open access
Semantic Scholar
Alteration of serum lipid profile, SRB1 loss, and impaired Nrf2 activation in CDKL5 disorder
A. Pecorelli, G. Belmonte, I. Meloni, F. Cervellati +11 more
2015Free Radical Biology & Medicine19 citations Open access
Semantic Scholar
Altered Bone Status in Rett Syndrome
A. Pecorelli, V. Cordone, M. L. Schiavone, C. Caffarelli +5 more
2021Life18 citations Open access
Semantic Scholar
Inflammatory protein response in CDKL5-Rett syndrome: evidence of a subclinical smouldering inflammation
Alessio Cortelazzo, C. De Felice, S. Leoncini, C. Signorini +6 more
2016Inflammation Research18 citations Open access
Semantic Scholar
Antibody Recognition in multiple sclerosis and rett syndrome using a collection of linear and cyclic N‐glucosylated antigenic probes
F. Real-Fernández, M. Di Pisa, G. Rossi, N. Auberger +11 more
2015Biopolymers18 citations
Semantic Scholar
Methyl-CpG-binding protein 2 (MECP2) mutation type is associated with bone disease severity in Rett syndrome
C. Caffarelli, S. Gonnelli, M. D. T. Pitinca, Silvia Camarri +3 more
2020BMC Medical Genetics17 citations Open access
Semantic Scholar
Increased isoprostanoid levels in brain from murine model of Krabbe disease - Relevance of isoprostanes, dihomo-isoprostanes and neuroprostanes to disease severity.
C. Signorini, V. Cardile, G. Pannuzzo, A. Graziano +8 more
2019Free Radical Biology & Medicine17 citations Open access
Semantic Scholar
NLRP3 Inflammasome-Mitochondrion loop in Autism Spectrum Disorder.
A. Vallese, V. Cordone, Francesca Ferrara, A. Guiotto +5 more
2024Free Radical Biology & Medicine16 citations Open access
Semantic Scholar
The constitutive activation of TLR4-IRAK1- NFκB axis is involved in the early NLRP3 inflammasome response in peripheral blood mononuclear cells of Rett syndrome patients.
V. Cordone, F. Ferrara, A. Pecorelli, A. Guiotto +5 more
2022Free Radical Biology & Medicine16 citations Open access
Semantic Scholar
Immune Dysfunction in Rett Syndrome Patients Revealed by High Levels of Serum Anti-N(Glc) IgM Antibody Fraction
A. Papini, F. Nuti, F. Real-Fernández, G. Rossi +12 more
2014Journal of Immunological Research16 citations Open access
Semantic Scholar
Protective role of mirtazapine in adult female Mecp2+/− mice and patients with Rett syndrome
Javier Flores Gutiérrez, C. De Felice, Giulia Natali, S. Leoncini +3 more
2020Journal of Neurodevelopmental Disorders15 citations Open access
Semantic Scholar
Intestinal Candida parapsilosis isolates from Rett syndrome subjects bear potential virulent traits and capacity to persist within the host
F. Strati, A. Calabró, C. Donati, C. De Felice +7 more
2018BMC Gastroenterology14 citations Open access
Semantic Scholar
The complexity of Rett syndrome models: Primary fibroblasts as a disease-in-a-dish reliable approach
V. Cordone, A. Pecorelli, F. Amicarelli, J. Hayek +1 more
201913 citations Open access
Semantic Scholar
Brain protein changes in Mecp2 mouse mutant models: Effects on disease progression of Mecp2 brain specific gene reactivation.
Alessio Cortelazzo, C. De Felice, J. Guy, A. Timperio +6 more
2020Journal of Proteomics12 citations
Semantic Scholar
Abnormal N-glycosylation pattern for brain nucleotide pyrophosphatase-5 (NPP-5) in Mecp2-mutant murine models of Rett syndrome.
Alessio Cortelazzo, C. De Felice, R. Guerranti, C. Signorini +15 more
2016Neurosciences research12 citations Open access
Semantic Scholar
Breathing Abnormalities During Sleep and Wakefulness in Rett Syndrome: Clinical Relevance and Paradoxical Relationship With Circulating Pro-oxidant Markers
S. Leoncini, C. Signorini, Lidia Boasiako, V. Scandurra +5 more
2022Frontiers in Neurology11 citations Open access
Semantic Scholar
Defective proteasome biogenesis into skin fibroblasts isolated from Rett syndrome subjects with MeCP2 non-sense mutations.
D. Sbardella, G. Tundo, V. Cunsolo, G. Grasso +22 more
2020Biochimica et Biophysica Acta - Molecular Basis of Disease11 citations Open access
Semantic Scholar
Red blood cells in Rett syndrome: oxidative stress, morphological changes and altered membrane organization
L. Ciccoli, C. De Felice, S. Leoncini, C. Signorini +5 more
2015Biological chemistry11 citations
Semantic Scholar
A proteomics approach to further highlight the altered inflammatory condition in Rett syndrome.
Vittoria Cicaloni, A. Pecorelli, V. Cordone, Laura Tinti +5 more
2020Archives of Biochemistry and Biophysics10 citations Open access
Semantic Scholar
Exploring the link between scavenger receptor B1 expression and chronic obstructive pulmonary disease pathogenesis
G. Valacchi, E. Maioli, C. Sticozzi, F. Cervellati +3 more
2015Annals of the New York Academy of Sciences10 citations
Semantic Scholar
A Comparative Study of Dual-X-ray Absorptiometry and Quantitative Ultrasonography for the Evaluating Bone Status in Subjects with Rett Syndrome
C. Caffarelli, J. Hayek, M. D. Tomai Pitinca, R. Nuti +1 more
2014Calcified Tissue International10 citations
Semantic Scholar
Antiglycative Activity and RAGE Expression in Rett Syndrome
V. Cordone, A. Pecorelli, M. Benedusi, S. Santini +4 more
2019Cells9 citations Open access
Semantic Scholar
Bone status in relation to ambulatory performance in girls with Rett syndrome: a 10-year longitudinal study
C. Caffarelli, Valentina Francolini, J. Hayek, G. Valacchi +3 more
2018Pediatric Research7 citations Open access
Semantic Scholar

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