Samuel Hsiao

Most-cited papers

1. A phase 2, randomized, double‐blind, placebo‐controlled study to evaluate the efficacy and safety of soticlestat as adjunctive therapy in pediatric patients with Dravet syndrome or Lennox–Gastaut syndrome (ELEKTRA)

   C. Hahn, Yu-Wu Jiang, V. Villanueva, M. Żołnowska +4 more

   2022Epilepsia74 citations Open access

   Semantic Scholar

   Save

2. Efficacy, safety, and tolerability of soticlestat as adjunctive therapy for the treatment of seizures in patients with Dup15q syndrome or CDKL5 deficiency disorder in an open-label signal-finding phase II study (ARCADE).

   S. Demarest, S. Jeste, Nitin Agarwal, Dimitrios Arkilo +3 more

   2023Epilepsy & Behavior20 citations Open access

   Semantic Scholar

   Save

3. Investigation of the absolute bioavailability, mass balance, metabolism, and excretion of the cholesterol 24‐hydroxylase inhibitor soticlestat in healthy volunteers

   Wei Yin, T. E. Ballard, Sean Xiaochun Zhu, Samuel Hsiao +8 more

   2023British Journal of Clinical Pharmacology9 citations Open access

   Semantic Scholar

   Save

4. Soticlestat as an adjunctive therapy in children and young adults with Dravet syndrome

   Joseph Sullivan, Kette D. Valente, V. Villanueva, A. Strzelczyk +11 more

   2026Epilepsia7 citations Open access

   Semantic Scholar

   Save

5. Oveporexton for Narcolepsy Type 1 - Results from Two Phase 3 Trials.

   Y. Dauvilliers, Emmanuel Mignot, Jakub Antczak, I. Arnulf +34 more

   2026New England Journal of Medicine1 citations Open access

   Semantic Scholar

   Save

6. 0737 Efficacy and Safety of Oveporexton (TAK-861), an Oral Orexin Receptor 2 Agonist, for Narcolepsy Type 1 Treatment: A Pooled Analysis of Phase 3 Studies

   Emmanuel Mignot, Y. Dauvilliers, R. Del Río Villegas, R. Khatami +11 more

   2026SLEEPJ1 citations

   Semantic Scholar

   Save

7. Human Abuse Potential Study of the Novel Antiepileptic Drug Soticlestat in Recreational Drug Users

   Kerri A Schoedel, Elizabeth Hanson, Mahnaz Asgharnejad, Samuel Hsiao +2 more

   2025Drug and Alcohol Dependence1 citations

   Semantic Scholar

   Save

8. Efficacy of Soticlestat Treatment by Seizure Type in Patients with Dravet Syndrome or Lennox–Gastaut Syndrome in a Phase 2, Randomized, Placebo-controlled Study (ELEKTRA) (P11-1.002)

   V. Murthy, D. Dlugos, Yasir Khan, Samuel Hsiao +2 more

   2023Wednesday, April 261 citations

   Semantic Scholar

   Save

9. The First Light: Efficacy and Safety of a Multi-dose Study of Oveporexton (TAK-861), an Oral Orexin Receptor Two Agonist for the Treatment of Narcolepsy Type One (S3.010)

   G. Plazzi, Emmanuel Mignot, I. Arnulf, R. Del Río Villegas +11 more

   2026Neurology0 citations

   Semantic Scholar

   Save

10. 0736 Effect of the Oral Orexin Receptor 2 Agonist Oveporexton (TAK-861) on Quality of Life in Individuals with NT1: A Pooled Analysis of Phase 3 Studies

    R. Del Río Villegas, S. Sivam, Alice Cai, Ye-Ting Du +4 more

    2026SLEEPJ0 citations

    Semantic Scholar

    Save