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R. Light · SciRah

Researcher profile · Semantic Scholar

R. Light

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R. Light — researcher profile on SciRah

h-index: 23
Works: 68
Citations: 2,043

Most-cited papers

Proportional assist ventilation. Results of an initial clinical trial.
M. Younes, A. Puddy, D. Roberts, R. Light +4 more
1992American Review of Respiratory Disease247 citations
Semantic Scholar
Double-blind randomised controlled trial of monoclonal antibody to human tumour necrosis factor in treatment of septic shock. NORASEPT II Study Group.
E. Abraham, A. Anzueto, G. Gutierrez, S. Tessler +15 more
1998The Lancet219 citations
Semantic Scholar
hemofiltration reverses left ventricular dysfunction during sepsis in dogs.
A. Gómez, R. Wang, Helmut Unruh, R. Light +4 more
1990Anesthesiology193 citations
Semantic Scholar
Early predictors of mortality for hospitalized patients suffering cardiopulmonary arrest.
D. Roberts, K. Landolfo, R. Light, K. Dobson
1990Chest137 citations
Semantic Scholar
Epidemiology and clinical spectrum of blastomycosis diagnosed at Manitoba hospitals.
Tracy L. Crampton, R. Light, G. Berg, M. Meyers +3 more
2002Clinical Infectious Diseases125 citations
Semantic Scholar
Intrapulmonary oxygen consumption in experimental pneumococcal pneumonia.
R. Light
1988Journal of applied physiology104 citations
Semantic Scholar
The clinical evaluation committee in a large multicenter phase 3 trial of drotrecogin alfa (activated) in patients with severe sepsis (PROWESS): Role, methodology, and results*
J. Dhainaut, P. Laterre, S. LaRosa, H. Levy +10 more
2003Critical Care Medicine96 citations
Semantic Scholar
Prophylaxis of recurrent urinary tract infection in female patients. Efficacy of low-dose, thrice-weekly therapy with trimethoprim-sulfamethoxazole.
G. Harding, F. J. Buckwold, T. Marrie, L. Thompson +2 more
1979Journal of the American Medical Association (JAMA)62 citations
Semantic Scholar
Effect of indomethacin on arterial oxygenation in critically ill patients with severe bacterial pneumonia.
P. Hanly, K. Dobson, D. Roberts, R. Light
1987The Lancet60 citations
Semantic Scholar
Pathophysiology of gas exchange and pulmonary perfusion in pneumococcal lobar pneumonia in dogs.
R. Light, S. Mink, L. Wood
1981Journal of applied physiology: respiratory, environmental and exercise physiology53 citations
Semantic Scholar
Pulmonary pathophysiology of pneumococcal pneumonia.
R. Light
1999Seminars in Respiratory Infections50 citations
Semantic Scholar
Effect of PEEP on gas exchange and pulmonary perfusion in canine lobar pneumonia.
S. Mink, R. Light, T. Cooligan, L. Wood
1981Journal of applied physiology: respiratory, environmental and exercise physiology43 citations
Semantic Scholar
The effects of decreasing low-molecular weight hemoglobin components of hemoglobin-based oxygen carriers in swine with hemorrhagic shock.
J. Rice, N. Philbin, R. Light, F. Arnaud +11 more
2008Journal of Trauma34 citations
Semantic Scholar
Effect of Continuous Arteriovenous Hemofiltration Combined with Systemic Vasopressor Therapy on Depressed Left Ventricular Contractility and Tissue Oxygen Delivery in Canine Escherichia coli Sepsis
S. Mink, P. Jha, R. Wang, J. Yang +3 more
1995Anesthesiology33 citations
Semantic Scholar
Effects of E. coli sepsis and myocardial depressant factor on interval-force relations in dog ventricle.
P. Jha, H. Jacobs, D. Bose, R. Wang +3 more
1993American Journal of Physiology32 citations
Semantic Scholar
Effect of alveolar hypoxia on pulmonary fluid filtration in in situ dog lungs.
L. Homik, Z. Bshouty, R. Light, Magdy Younes
1988Journal of applied physiology31 citations
Semantic Scholar
The effects of methoxamine and epinephrine on survival and regional distribution of cardiac output in dogs with prolonged ventricular fibrillation.
Daniel Roberts, K. Landolfo, K. Dobson, R. Light
1990Chest30 citations
Semantic Scholar
A randomized, double-blind comparison of methoxamine and epinephrine in human cardiopulmonary arrest.
W. Patrick, J. Freedman, T. Mcewen, R. Light +2 more
1995American Journal of Respiratory and Critical Care Medicine29 citations
Semantic Scholar
Early but not delayed continuous arteriovenous hemofiltration improves cardiovascular function in sepsis in dogs
S. Mink, Xing Li, D. Bose, M. Gu +3 more
1999Intensive Care Medicine27 citations Open access
Semantic Scholar
Effect of pneumococcal lobar pneumonia on canine lung mechanics.
S. Mink, R. Light, L. Wood
1981Journal of applied physiology: respiratory, environmental and exercise physiology27 citations
Semantic Scholar
Lysozyme: a mediator of myocardial depression and adrenergic dysfunction in septic shock in dogs.
S. Mink, H. Jacobs, D. Bose, K. Duke +3 more
2003Journal of Molecular and Cellular Cardiology26 citations
Semantic Scholar
Effect of increased afterload on right ventricular function in newborn pigs.
J. Belik, R. Light
1989Journal of applied physiology25 citations
Semantic Scholar
Effect of cyclooxygenase blockade on gas exchange and hemodynamics in Pseudomonas pneumonia.
P. Hanly, A. Sienko, R. Light
1987Journal of applied physiology24 citations
Semantic Scholar
Role of prostacyclin and thromboxane in the circulatory changes of acute bacteremic Pseudomonas pneumonia in dogs.
P. Hanly, A. Sienko, R. Light
1988American Review of Respiratory Disease21 citations
Semantic Scholar
Management and Outcomes of Acute Respiratory Distress Syndrome Caused by Blastomycosis
Ilan S. Schwartz, J. Embil, Atul Sharma, S. Goulet +1 more
2016Medicine18 citations Open access
Semantic Scholar
N,N′-DIACETYLCHITOBIOSE, AN INHIBITOR OF LYSOZYME, REVERSES MYOCARDIAL DEPRESSION AND LESSENS NOREPINEPHRINE REQUIREMENTS IN ESCHERICHIA COLI SEPSIS IN DOGS
S. Mink, Krika Kasian, H. Jacobs, Zhao-Qin Cheng +1 more
2007Shock18 citations Open access
Semantic Scholar
Lysozyme binding to endocardial endothelium mediates myocardial depression by the nitric oxide guanosine 3',5' monophosphate pathway in sepsis.
S. Mink, R. Bose, D. Roberts, H. Jacobs +4 more
2005Journal of Molecular and Cellular Cardiology18 citations
Semantic Scholar
Histamine H3 activation depresses cardiac function in experimental sepsis.
Xing Li, Gregg M. Eschun, D. Bose, H. Jacobs +3 more
1998Journal of applied physiology18 citations
Semantic Scholar
The Effect of Unilateral PEEP on Gas Exchange and Pulmonary Perfusion in Canine Lobar Pneumonia
R. Light, S. Mink, L. Wood
1981Anesthesiology18 citations Open access
Semantic Scholar
Indomethacin and acetylsalicylic acid reduce intrapulmonary shunt in experimental pneumococcal pneumonia.
R. Light
1986American Review of Respiratory Disease17 citations
Semantic Scholar
A blinding headache.
J. Embil, M. Kramer, S. Kinnear, R. Light
1997The Lancet15 citations
Semantic Scholar
Lysozyme, a mediator of sepsis that produces vasodilation by hydrogen peroxide signaling in an arterial preparation.
S. Mink, Krika Kasian, Luis E. Santos-Martinez, H. Jacobs +3 more
2008American Journal of Physiology. Heart and Circulatory Physiology14 citations
Semantic Scholar
Characterization of membrane N-glycan binding sites of lysozyme for cardiac depression in sepsis
H. Jacobs, S. Mink, K. Duke, D. Bose +4 more
2004Intensive Care Medicine14 citations
Semantic Scholar
Tumour necrosis factor-α, but not septic plasma depresses cardiac myofilament contraction
M. Gu, R. Bose, D. Bose, Juan Yang +4 more
199814 citations Open access
Semantic Scholar
Lysozyme, a mediator of sepsis that intrinsically generates hydrogen peroxide to cause cardiovascular dysfunction.
S. Mink, H. Jacobs, Zhao-Qin Cheng, Krika Kasian +2 more
2009American Journal of Physiology. Heart and Circulatory Physiology12 citations
Semantic Scholar
Effect of sodium nitroprusside and diethylcarbamazine on hypoxic pulmonary vasoconstriction and regional distribution of pulmonary blood flow in experimental pneumonia.
R. Light
1996American Journal of Respiratory and Critical Care Medicine12 citations
Semantic Scholar
Compression of the left main bronchus between a descending thoracic aortic aneurysm and an enlarged right pulmonary artery.
Charles Penner, Bruce Maycher, R. Light
1994Chest11 citations
Semantic Scholar
Tumour necrosis factor-alpha, but not septic plasma depresses cardiac myofilament contraction.
M. Gu, R. Bose, D. Bose, J. Yang +4 more
1998Canadian Journal of Anaesthesia-journal Canadien D Anesthesie9 citations
Semantic Scholar
The pulmonary vascular effects of dopamine, dobutamine, and isoproterenol in unilobar pulmonary edema in dogs.
R. Light, J. Ali, Peter H. Breen, Lawrence D. H. Wood
1988Journal of Surgical Research9 citations
Semantic Scholar
The physiology of recovery in experimental pneumococcal pneumonia.
R. Light, S. Mink, T. Cooligan, L. Wood
1983Clinical and investigative medicine. Medecine clinique et experimentale9 citations
Semantic Scholar
Trimethoprim Alone in the Treatment and Prophylaxis of Urinary Tract Infection
R. Light, A. Ronald, G. Harding, J. Dikkema +2 more
19819 citations
Semantic Scholar
Sepsis causes presynaptic histamine H3 and alpha2-adrenergic dysfunction in canine myocardium.
Zao-Qin Cheng, D. Bose, H. Jacobs, R. Light +1 more
2002Cardiovascular Research8 citations Open access
Semantic Scholar
The effect of repeated intermittent hypoxia on pulmonary vasoconstriction in the newborn.
Jaques Belik, Anna Sieńko, R. Light
1990Canadian Journal of Physiology and Pharmacology8 citations
Semantic Scholar
Plasma volume expansion in canine pneumococcal pneumonia: its effects on respiratory gas exchange and pneumonia size.
T. Cooligan, R. Light, L. Wood, S. Mink
1982American Review of Respiratory Disease8 citations
Semantic Scholar
Lysozyme, a mediator of sepsis, impairs the cardiac neural adrenergic response by nonendothelial release of NO and inhibitory G protein signaling.
S. Mink, Zhao-Qin Cheng, R. Bose, H. Jacobs +4 more
2007American Journal of Physiology. Heart and Circulatory Physiology7 citations
Semantic Scholar
Central Hemodynamic and Regional Blood Flow Changes in the Newborn with Right Ventricular Hypertension
J. Belik, K. Baron, R. Light
1989Pediatric Research7 citations
Semantic Scholar
Lung mechanics, gas exchange, pulmonary perfusion, and hemodynamics in a canine model of acutePseudomonas pneumonia
P. Hanly, R. Light
2007Lung6 citations
Semantic Scholar
Effects of prostaglandin E1 on the pulmonary vascular pressure-flow relationship in canine pulmonary hypertension
J. Ducas, R. Light, L. Girling, Usha Schick +1 more
19886 citations
Semantic Scholar
Naloxone for septic shock.
A. M. A. Soulioti, D. Roberts, R. Light
19885 citations
Semantic Scholar
Hyperventilation in the Newborn Piglet Does Not Increase Whole Body Oxygen Consumption as Seen in Mature Animals
J. Belik, R. Light
1988Pediatric Research4 citations
Semantic Scholar

Frequent co-authors

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S. Mink×21
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H. Jacobs×14
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D. Bose×11
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Zhao-Qin Cheng×7
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L. Wood — researcher profile on SciRah

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R. Bose — researcher profile on SciRah

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D. Roberts — researcher profile on SciRah

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Krika Kasian×4

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Krika Kasian — researcher profile on SciRah

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R. Wang — researcher profile on SciRah

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K. Dobson — researcher profile on SciRah

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J. Embil — researcher profile on SciRah