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F. Szoka · SciRah

Researcher profile · Semantic Scholar

F. Szoka

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F. Szoka — researcher profile on SciRah

h-index: 67
Works: 205
Citations: 24K

Most-cited papers

Soluble Polymer Carriers for the Treatment of Cancer: The Importance of Molecular Architecture
M. E. Fox, F. Szoka, J. Fréchet
2009Accounts of Chemical Research691 citations Open access
Semantic Scholar
Lipid-based Nanoparticles for Nucleic Acid Delivery
Wei-Jun Li, F. Szoka
2007Pharmaceutical Research633 citations
Semantic Scholar
A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas
Cameron C. Lee, Elizabeth R. Gillies, M. E. Fox, S. Guillaudeu +3 more
2006Proceedings of the National Academy of Sciences of the United States of America604 citations Open access
Semantic Scholar
Cancer Nanomedicines: So Many Papers and So Few Drugs!
V. Venditto, F. Szoka
2012Advanced Drug Delivery Reviews529 citations Open access
Semantic Scholar
BCAA catabolism in brown fat controls energy homeostasis through SLC25A44
T. Yoneshiro, Qiang Wang, Kazuki Tajima, M. Matsushita +32 more
2019Nature464 citations Open access
Semantic Scholar
Anticancer therapeutics: targeting macromolecules and nanocarriers to hyaluronan or CD44, a hyaluronan receptor.
Virginia M Platt, F. Szoka
2008Molecular Pharmaceutics447 citations Open access
Semantic Scholar
Nucleic acid delivery: the missing pieces of the puzzle?
J. Nguyen, F. Szoka
2012Accounts of Chemical Research344 citations Open access
Semantic Scholar
Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency
David N. Nguyen, Theodore L. Roth, P. J. Li, P. Chen +10 more
2019Nature Biotechnology278 citations Open access
Semantic Scholar
The neonatal Fc receptor, FcRn, as a target for drug delivery and therapy
Jonathan T. Sockolosky, F. Szoka
2015Advanced Drug Delivery Reviews228 citations Open access
Semantic Scholar
Dependence of Pharmacokinetics and Biodistribution on Polymer Architecture: Effect of Cyclic Versus Linear Polymers
Norased Nasongkla, Bo Chen, Nichole Macaraeg, M. E. Fox +2 more
2009Journal of the American Chemical Society214 citations Open access
Semantic Scholar
Quantification of Plasmid DNA Copies in the Nucleus after Lipoplex and Polyplex Transfection
Richard N. Cohen, M. van der Aa, Nichole Macaraeg, Ai-Ping Lee +1 more
2009Journal of Controlled Release208 citations Open access
Semantic Scholar
PEGylated dendrimers with core functionality for biological applications.
S. Guillaudeu, M. E. Fox, Y. Haidar, Edward E. Dy +2 more
2008Bioconjugate chemistry185 citations
Semantic Scholar
The Effect of Polymer Backbone Chemistry on the Induction of the Accelerated Blood Clearance in Polymer Modified Liposomes
Paul H. Kierstead, H. Okochi, V. Venditto, Tracy C Chuong +3 more
2015Journal of Controlled Release182 citations Open access
Semantic Scholar
Macrophage-Based Cell Therapies: The Long and Winding Road
S. Lee, S. Kivimae, Aaron Dolor, F. Szoka
2016Journal of Controlled Release170 citations Open access
Semantic Scholar
Designer lipids for drug delivery: from heads to tails
Aditya G. Kohli, Paul H. Kierstead, V. Venditto, Colin L. Walsh +1 more
2014Journal of Controlled Release152 citations Open access
Semantic Scholar
The Influence of Polymer Topology on Pharmacokinetics: Differences Between Cyclic and Linear PEGylated Poly(acrylic Acid) Comb Polymers
Bo Chen, K. Jerger, J. Fréchet, F. Szoka
2009Journal of Controlled Release151 citations Open access
Semantic Scholar
Synthesis and In Vivo Antitumor Efficacy of PEGylated Poly(L-lysine) Dendrimer-Camptothecin Conjugates
M. E. Fox, S. Guillaudeu, J. Fréchet, K. Jerger +2 more
2009Molecular Pharmaceutics142 citations Open access
Semantic Scholar
Low‐pH‐sensitive poly(ethylene glycol) (PEG)‐stabilized plasmid nanolipoparticles: effects of PEG chain length, lipid composition and assembly conditions on gene delivery
Wei-Jun Li, Z. Huang, J. A. Mackay, S. Grube +1 more
2005Journal of Gene Medicine141 citations
Semantic Scholar
Digesting a path forward – the utility of collagenase tumor treatment for improved drug delivery
Aaron Dolor, F. Szoka
2018Molecular Pharmaceutics133 citations Open access
Semantic Scholar
Disterolphospholipids: Non-exchangeable Lipids and Their Application to Liposomal Drug Delivery
Z. Huang, M. Jaafari, F. Szoka
2009Angewandte Chemie127 citations Open access
Semantic Scholar
Sterol-Modified Phospholipids: Cholesterol and Phospholipid Chimeras with Improved Biomembrane Properties
Z. Huang, F. Szoka
2008Journal of the American Chemical Society119 citations Open access
Semantic Scholar
Barriers to carrier mediated drug and gene delivery to brain tumors.
Grace H. Huynh, D. Deen, F. Szoka
2006Journal of Controlled Release115 citations
Semantic Scholar
Periplasmic production via the pET expression system of soluble, bioactive human growth hormone
Jonathan T. Sockolosky, F. Szoka
2012Protein Expression and Purification103 citations Open access
Semantic Scholar
Design, synthesis, and biological evaluation of a robust, biodegradable dendrimer.
Derek G. van der Poll, Heidi M. Kieler-Ferguson, W. C. Floyd, S. Guillaudeu +3 more
2010Bioconjugate chemistry101 citations Open access
Semantic Scholar
Improving the distribution of Doxil® in the tumor matrix by depletion of tumor hyaluronan
Aditya G. Kohli, S. Kivimae, Matthew R. Tiffany, F. Szoka
2014Journal of Controlled Release81 citations Open access
Semantic Scholar
Inverse-phosphocholine lipids: A remix of a common phospholipid
E. K. Perttu, Aditya G. Kohli, F. Szoka
2012Journal of the American Chemical Society75 citations Open access
Semantic Scholar
Antitumor Effect of Folate-Targeted Liposomal Doxorubicin in KB Tumor-Bearing Mice after Intravenous Administration
Kareen Riviere, Z. Huang, K. Jerger, Nichole Macaraeg +1 more
2010Journal of drug targeting (Print)70 citations Open access
Semantic Scholar
Facile synthesis of multivalent nitrilotriacetic acid (NTA) and NTA conjugates for analytical and drug delivery applications.
Z. Huang, Joshua I. Park, Douglas S. Watson, Peter Hwang +1 more
2006Bioconjugate chemistry68 citations
Semantic Scholar
Tris-Nitrilotriacetic Acids of Sub-nanomolar Affinity Toward Hexahistidine Tagged Molecules
Z. Huang, Peter Hwang, Douglas S. Watson, Li-Min Cao +1 more
2009Bioconjugate chemistry61 citations Open access
Semantic Scholar
Engineering neonatal Fc receptor-mediated recycling and transcytosis in recombinant proteins by short terminal peptide extensions
Jonathan T. Sockolosky, Matthew R. Tiffany, F. Szoka
2012Proceedings of the National Academy of Sciences of the United States of America60 citations Open access
Semantic Scholar
Intravitreal Administration of HA-1077, a ROCK Inhibitor, Improves Retinal Function in a Mouse Model of Huntington Disease
Mei Li, D. Yasumura, Aye Aye K. Ma, M. Matthes +6 more
2013PLoS ONE57 citations Open access
Semantic Scholar
Antibody Response to Polyhistidine-Tagged Peptide and Protein Antigens Attached to Liposomes via Lipid-Linked Nitrilotriacetic Acid in Mice
Douglas S. Watson, Virginia M Platt, Li-Min Cao, V. Venditto +1 more
2010Clinical and Vaccine Immunology55 citations Open access
Semantic Scholar
Efficient synthesis of an aldehyde functionalized hyaluronic acid and its application in the preparation of hyaluronan-lipid conjugates.
D. Ruhela, Kareen Riviere, F. Szoka
2006Bioconjugate chemistry54 citations
Semantic Scholar
Anti-tumor activity of liposome encapsulated fluoroorotic acid as a single agent and in combination with liposome irinotecan
Kareen Riviere, Heidi M. Kieler-Ferguson, K. Jerger, F. Szoka
2011Journal of Controlled Release51 citations Open access
Semantic Scholar
Characterization of the Colloidal Properties, In vitro Antifungal Activity, Antileishmanial Activity and Toxicity in Mice of a Distigmasterylhemisuccinoyl-glycerophosphocholine Liposome-Intercalated Amphotericin B
M. Iman, Z. Huang, F. Szoka, M. Jaafari
2011International journal of pharmaceutics50 citations Open access
Semantic Scholar
Clinical developments of chemotherapeutic nanomedicines: polymers and liposomes for delivery of camptothecins and platinum (II) drugs.
Heidi M. Kieler-Ferguson, J. Fréchet, F. Szoka
2013Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology49 citations
Semantic Scholar
Influence of multivalent nitrilotriacetic acid lipid-ligand affinity on the circulation half-life in mice of a liposome-attached his6-protein
Virginia M Platt, Z. Huang, Li-Min Cao, Matthew R. Tiffany +2 more
2010Bioconjugate chemistry49 citations Open access
Semantic Scholar
Synthesis, characterization, and evaluation of ionizable lysine-based lipids for siRNA delivery.
Colin L. Walsh, J. Nguyen, Matthew R. Tiffany, F. Szoka
2013Bioconjugate chemistry46 citations Open access
Semantic Scholar
An intramolecular cyclization reaction is responsible for the in vivo inefficacy and apparent pH insensitive hydrolysis kinetics of hydrazone carboxylate derivatives of doxorubicin.
Cameron C. Lee, Andrew T Cramer, F. Szoka, J. Fréchet
2006Bioconjugate chemistry44 citations
Semantic Scholar
Encapsulation, controlled release, and antitumor efficacy of cisplatin delivered in liposomes composed of sterol-modified phospholipids
Heidi M. Kieler-Ferguson, Darren Chan, Jonathan T. Sockolosky, L. Finney +3 more
2017European Journal of Pharmaceutical Sciences43 citations Open access
Semantic Scholar
Role of lipid structure in the humoral immune response in mice to covalent lipid-peptides from the membrane proximal region of HIV-1 gp41
Douglas S. Watson, F. Szoka
2009Vaccine41 citations Open access
Semantic Scholar
Unsaturated cationic ortho esters for endosome permeation in gene delivery.
Hai-Gang Chen, Huizhen Zhang, C. McCallum, F. Szoka +1 more
2007Journal of Medicinal Chemistry41 citations
Semantic Scholar
Fusion of a Short Peptide that Binds Immunoglobulin G to a Recombinant Protein Substantially Increases Its Plasma Half-Life in Mice
Jonathan T. Sockolosky, S. Kivimae, F. Szoka
2014PLoS ONE39 citations Open access
Semantic Scholar
Phosphatase-Triggered Fusogenic Liposomes for Cytoplasmic Delivery of Cell-Impermeable Compounds
J. P. Michael Motion, J. Nguyen, F. Szoka
2012Angewandte Chemie38 citations Open access
Semantic Scholar
Development of a flow‐through USP 4 apparatus drug release assay for the evaluation of amphotericin B liposome
Jie Tang, Santhana Srinivasan, W. Yuan, Ming Ran +8 more
2019European journal of pharmaceutics and biopharmaceutics37 citations
Semantic Scholar
Development of a Flow-Through USP-4 Apparatus Drug Release Assay to Evaluate Doxorubicin Liposomes
W. Yuan, Rui Kuai, Zhipeng Dai, Yue Yuan +6 more
2016AAPS Journal37 citations
Semantic Scholar
HIV TAT peptide modifies the distribution of DNA nanolipoparticles following convection-enhanced delivery.
J. A. MacKay, Wei-Jun Li, Z. Huang, Edward E. Dy +5 more
2008Molecular Therapy36 citations Open access
Semantic Scholar
Synthesis and Properties of Star-Comb Polymers and Their Doxorubicin Conjugates
Bo Chen, Derek G. van der Poll, K. Jerger, W. C. Floyd +2 more
2011Bioconjugate chemistry35 citations Open access
Semantic Scholar
Matrix modification for enhancing the transport properties of the human cartilage endplate to improve disc nutrition
Aaron Dolor, Sara L. Sampson, A. Lazar, J. Lotz +2 more
2019PLoS ONE33 citations Open access
Semantic Scholar
Molecular motors as drug delivery vehicles.
Richard N. Cohen, Mark J. Rashkin, Xin Wen, F. Szoka
2005Drug Discovery Today : Technologies32 citations
Semantic Scholar

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J. Fréchet×11
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K. Jerger×6
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M. E. Fox×5
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Jonathan T. Sockolosky

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