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W. MacLellan · SciRah

Researcher profile · Semantic Scholar

W. MacLellan

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W. MacLellan — researcher profile on SciRah

h-index: 44
Works: 113
Citations: 8,787

Most-cited papers

Cardiac Troponin I Is Associated With Impaired Hemodynamics, Progressive Left Ventricular Dysfunction, and Increased Mortality Rates in Advanced Heart Failure
Tamara B. Horwich, J. Patel, W. MacLellan, G. Fonarow
2003Circulation619 citations Open access
Semantic Scholar
Cardiac myocyte cell cycle control in development, disease, and regeneration.
P. Ahuja, P. Sdek, W. MacLellan
2007Physiological Reviews600 citations Open access
Semantic Scholar
Three-dimensional electrospun ECM-based hybrid scaffolds for cardiovascular tissue engineering.
Sepideh Heydarkhan‐Hagvall, K. Schenke-Layland, A. Dhanasopon, F. Rofail +5 more
2008Biomaterials440 citations Open access
Semantic Scholar
Statin therapy is associated with improved survival in ischemic and non-ischemic heart failure.
Tamara B. Horwich, W. MacLellan, G. Fonarow
2003Journal of the American College of Cardiology344 citations Open access
Semantic Scholar
Safety and Feasibility of Autologous Myoblast Transplantation in Patients With Ischemic Cardiomyopathy: Four-Year Follow-Up
N. Dib, R. Michler, F. Pagani, S. Wright +23 more
2005Circulation339 citations Open access
Semantic Scholar
Mapping the first stages of mesoderm commitment during differentiation of human embryonic stem cells
D. Evseenko, Yu-Hua Zhu, K. Schenke-Layland, Jeffrey Kuo +7 more
2010Proceedings of the National Academy of Sciences of the United States of America272 citations Open access
Semantic Scholar
Reprogrammed Mouse Fibroblasts Differentiate into Cells of the Cardiovascular and Hematopoietic Lineages
K. Schenke-Layland, Katrin E. Rhodes, E. Angelis, Yekaterina Butylkova +7 more
2008Stem Cells249 citations Open access
Semantic Scholar
Regulation of the mammalian cell cycle: a model of the G1-to-S transition.
Zhi-Lin Qu, J. Weiss, W. MacLellan
2003American Journal of Physiology - Cell Physiology189 citations
Semantic Scholar
Effects of a home-based exercise program on clinical outcomes in heart failure.
K. Dracup, L. Evangelista, M. Hamilton, V. Erickson +5 more
2007American Heart Journal157 citations Open access
Semantic Scholar
Adipose tissue-derived cells improve cardiac function following myocardial infarction.
K. Schenke-Layland, Brian M. Strem, M. Jordan, Michael T. DeEmedio +4 more
2009Journal of Surgical Research156 citations Open access
Semantic Scholar
Expression of cardiomyocytic markers on adipose tissue-derived cells in a murine model of acute myocardial injury.
Brian M. Strem, Min Zhu, Zeni C. Alfonso, Eric J Daniels +5 more
2005Cytotherapy152 citations
Semantic Scholar
Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice.
P. Ahuja, Peng Zhao, E. Angelis, Hongmei Ruan +7 more
2010Journal of Clinical Investigation150 citations Open access
Semantic Scholar
Mithramycin Is a Gene-Selective Sp1 Inhibitor That Identifies a Biological Intersection between Cancer and Neurodegeneration
Sama F. Sleiman, Brett C. Langley, M. Basso, Jill Berlin +13 more
2011Journal of Neuroscience137 citations Open access
Semantic Scholar
Overlapping Roles of Pocket Proteins in the Myocardium Are Unmasked by Germ Line Deletion of p130 plus Heart-Specific Deletion of Rb
W. MacLellan, Alejandro J. Garcia, H. Oh, P. Frenkel +3 more
2005Molecular and Cellular Biology127 citations Open access
Semantic Scholar
Hypertrophic growth in cardiac myocytes is mediated by Myc through a Cyclin D2‐dependent pathway
Weiguang Zhong, Songyan Mao, S. Tobis, E. Angelis +5 more
2006EMBO Journal121 citations Open access
Semantic Scholar
Muscle mechanoreceptor sensitivity in heart failure.
H. Middlekauff, Josephine Chiu, M. Hamilton, G. Fonarow +4 more
2004American Journal of Physiology. Heart and Circulatory Physiology120 citations
Semantic Scholar
Human Adipose Stem Cells: A Potential Cell Source for Cardiovascular Tissue Engineering
Sepideh Heydarkhan‐Hagvall, K. Schenke-Layland, Jin Q. Yang, Sanaz Heydarkhan +4 more
2008Cells Tissues Organs119 citations
Semantic Scholar
Collagen IV Induces Trophoectoderm Differentiation of Mouse Embryonic Stem Cells
K. Schenke-Layland, E. Angelis, Katrin E. Rhodes, Sepideh Heydarkhan‐Hagvall +2 more
2007Stem Cells115 citations Open access
Semantic Scholar
Systems-based approaches to cardiovascular disease
W. MacLellan, Yi-Bin Wang, A. Lusis
2012Nature Reviews Cardiology102 citations Open access
Semantic Scholar
Analysis of oxygen transport in a diffusion‐limited model of engineered heart tissue
David A. Brown, W. MacLellan, H. Laks, J. Dunn +2 more
2007Biotechnology and Bioengineering102 citations
Semantic Scholar
Divergent Mitochondrial Biogenesis Responses in Human Cardiomyopathy
P. Ahuja, J. Wanagat, Zhihua Wang, Yi-Bin Wang +5 more
2013Circulation101 citations Open access
Semantic Scholar
Feasibility and Safety of Autologous Myoblast Transplantation in Patients with Ischemic Cardiomyopathy
N. Dib, P. McCarthy, Ann Campbell, M. Yeager +13 more
2005Cell Transplantation96 citations Open access
Semantic Scholar
Optimized preservation of extracellular matrix in cardiac tissues: implications for long-term graft durability.
K. Schenke-Layland, Jian-Song Xie, Sepideh Heydarkhan‐Hagvall, S. Hamm-Alvarez +3 more
2007Annals of Thoracic Surgery84 citations Open access
Semantic Scholar
Recapitulation of the embryonic cardiovascular progenitor cell niche
K. Schenke-Layland, A. Nsair, B. van Handel, E. Angelis +6 more
2011Biomaterials77 citations Open access
Semantic Scholar
Gene editing to prevent ventricular arrhythmias associated with cardiomyocyte cell therapy
S. Marchianò, Kenta Nakamura, H. Reinecke, L. Neidig +25 more
2023Cell Stem Cell76 citations Open access
Semantic Scholar
Increased degradation of extracellular matrix structures of lacrimal glands implicated in the pathogenesis of Sjögren's syndrome.
K. Schenke-Layland, Jian-Song Xie, E. Angelis, B. Starcher +4 more
2008Matrix Biology75 citations Open access
Semantic Scholar
Identification of the Critical Extracellular Matrix Proteins that Promote Human Embryonic Stem Cell Assembly
D. Evseenko, K. Schenke-Layland, G. Dravid, Yu-Hua Zhu +5 more
2009Stem Cells and Development70 citations
Semantic Scholar
Altered proteome biology of cardiac mitochondria under stress conditions.
Jun Zhang, David A. Liem, Michael Mueller, Yueju Wang +10 more
2008Journal of Proteome Research65 citations Open access
Semantic Scholar
The use of three-dimensional nanostructures to instruct cells to produce extracellular matrix for regenerative medicine strategies
K. Schenke-Layland, F. Rofail, Sanaz Heydarkhan, J. Gluck +7 more
2009Biomaterials64 citations Open access
Semantic Scholar
Quantitative second harmonic generation imaging of cartilage damage
K. Brockbank, W. MacLellan, Jian-Song Xie, S. Hamm-Alvarez +2 more
2008Cell and Tissue Banking64 citations
Semantic Scholar
Elevated Serum Levels of the CXCR3 Chemokine ITAC Are Associated With the Development of Transplant Coronary Artery Disease
J. Kao, J. Kobashigawa, M. Fishbein, W. MacLellan +3 more
2003Circulation64 citations Open access
Semantic Scholar
Regulation of RNA polymerase III transcription during hypertrophic growth
S. Goodfellow, Fiona Innes, Louise E. Derblay, W. MacLellan +2 more
2006EMBO Journal63 citations Open access
Semantic Scholar
Cardiomyopathy is associated with structural remodelling of heart valve extracellular matrix.
K. Schenke-Layland, U. Stock, A. Nsair, Jian-Song Xie +7 more
2009European Heart Journal61 citations Open access
Semantic Scholar
Hypertrophy and heart failure in mice overexpressing the cardiac sodium-calcium exchanger.
Kenneth P. Roos, M. Jordan, Michael C. Fishbein, M. Ritter +8 more
2007Journal of Cardiac Failure60 citations Open access
Semantic Scholar
Single-cell imaging and transcriptomic analyses of endogenous cardiomyocyte dedifferentiation and cycling
Yi-Qiang Zhang, Nuria Gago-López, Ning Li, Zhen-He Zhang +5 more
2019Cell Discovery57 citations Open access
Semantic Scholar
Influence of Systematically Varied Nano-Scale Topography on Cell Morphology and Adhesion
Sepideh Heydarkhan‐Hagvall, Chang-Hwan Choi, J. Dunn, Sanaz Heydarkhan +3 more
2007Cell Communication & Adhesion52 citations Open access
Semantic Scholar
THY-1 Receptor Expression Differentiates Cardiosphere-Derived Cells with Divergent Cardiogenic Differentiation Potential
Nuria Gago-López, Obinna Awaji, Yi-Qiang Zhang, Christopher Ko +4 more
2014Stem Cell Reports51 citations Open access
Semantic Scholar
Heart failure is associated with impaired anti-inflammatory and antioxidant properties of high-density lipoproteins.
J. Kim, S. Hama, G. Hough, M. Navab +4 more
2013American Journal of Cardiology44 citations
Semantic Scholar
Abcc6 deficiency causes increased infarct size and apoptosis in a mouse cardiac ischemia-reperfusion (I/R) model
I. Mungrue, Peng Zhao, Yu-Cheng Yao, H. Meng +8 more
2011Arteriosclerosis, Thrombosis and Vascular Biology44 citations Open access
Semantic Scholar
A Cyclin D2–Rb Pathway Regulates Cardiac Myocyte Size and RNA Polymerase III After Biomechanical Stress in Adult Myocardium
E. Angelis, Alejandro J. Garcia, Shing S. Chan, K. Schenke-Layland +6 more
2008Circulation Research39 citations Open access
Semantic Scholar
Lymphocytic infiltration leads to degradation of lacrimal gland extracellular matrix structures in NOD mice exhibiting a Sjögren’s syndrome-like exocrinopathy
K. Schenke-Layland, Jian-Song Xie, M. Magnusson, E. Angelis +5 more
2009Experimental Eye Research37 citations Open access
Semantic Scholar
Coordination of cell growth and cell division: a mathematical modeling study
Zhi-Lin Qu, J. Weiss, W. MacLellan
2004Journal of Cell Science37 citations Open access
Semantic Scholar
Induced Pluripotent Stem Cells for Regenerative Cardiovascular Therapies and Biomedical Discovery
A. Nsair, W. MacLellan
2011Advanced Drug Delivery Reviews36 citations Open access
Semantic Scholar
Hybrid coaxial electrospun nanofibrous scaffolds with limited immunological response created for tissue engineering
J. Gluck, P. Rahgozar, N. Ingle, Fironia Rofail +7 more
2011Journal of Biomedical Materials Research. Part B - Applied biomaterials34 citations Open access
Semantic Scholar
Epigenetic regulation of cardiac myocyte differentiation
Kyohei Oyama, Danny El-Nachef, Yi-Qiang Zhang, P. Sdek +1 more
2014Frontiers in Genetics31 citations Open access
Semantic Scholar
The Role of E2F-1 and Downstream Target Genes in Mediating Ischemia/Reperfusion Injury In Vivo
E. Angelis, Peng Zhao, Rui Zhang, J. Goldhaber +1 more
2011Journal of Molecular and Cellular Cardiology26 citations Open access
Semantic Scholar
Cyclooxygenase products sensitize muscle mechanoreceptors in humans with heart failure.
H. Middlekauff, Josephine Chiu, M. Hamilton, G. Fonarow +4 more
2008American Journal of Physiology. Heart and Circulatory Physiology25 citations
Semantic Scholar
The role of cytoprotective cytokines in cardiac ischemia/reperfusion injury.
C. Anderson, Sepideh Heydarkhan‐Hagvall, K. Schenke-Layland, Jin-Quan Yang +8 more
2008Journal of Surgical Research24 citations
Semantic Scholar
Modulation of gene expression in neonatal rat cardiomyocytes by surface modification of polylactide-co-glycolide substrates.
David A. Brown, R. Beygui, W. MacLellan, H. Laks +2 more
2005Journal of Biomedical Materials Research. Part A24 citations
Semantic Scholar
Cyclin Dependent Kinase 2 Signaling Regulates Myocardial Ischemia/Reperfusion Injury
David A. Liem, Peng Zhao, E. Angelis, Shing S. Chan +6 more
2008Journal of Molecular and Cellular Cardiology23 citations Open access
Semantic Scholar

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