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J. Hardcastle · SciRah

Researcher profile · Semantic Scholar

J. Hardcastle

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J. Hardcastle — researcher profile on SciRah

h-index: 39
Works: 207
Citations: 10K

Most-cited papers

Randomised controlled trial of faecal-occult-blood screening for colorectal cancer.
J. Hardcastle, J. Chamberlain, M. Robinson, S. M. Moss +4 more
1989The Lancet2,812 citations
Semantic Scholar
Randomised, controlled trial of faecal occult blood screening for colorectal cancer. Results for first 107,349 subjects.
J. Hardcastle, J. Chamberlain, J. Sheffield, T. W. Balfour +6 more
1989The Lancet318 citations
Semantic Scholar
Effect of faecal occult blood screening on mortality from colorectal cancer: results from a randomised controlled trial
J. Scholefield, S. Moss, F. Sufi, C. Mangham +1 more
2002Gut316 citations Open access
Semantic Scholar
Effect of aspirin and non-steroidal anti-inflammatory drugs on colorectal adenomas: case-control study of subjects participating in the Nottingham faecal occult blood screening programme.
R. F. A. Logan, Julian Little, P. G. Hawtin, J. Hardcastle
1993British medical journal285 citations Open access
Semantic Scholar
Inhibition of organ invasion by the matrix metalloproteinase inhibitor batimastat (BB-94) in two human colon carcinoma metastasis models.
S. Watson, T. Morris, Graham Robinson, M. Crimmin +2 more
1995Cancer Research181 citations
Semantic Scholar
A prospective multicenter evaluation of new fecal occult blood tests in patients undergoing colonoscopy
P. Greenberg, L. Bertario, R. Gnauck, O. Kronborg +6 more
2000American Journal of Gastroenterology127 citations
Semantic Scholar
Gastrimmune raises antibodies that neutralize amidated and glycine-extended gastrin-17 and inhibit the growth of colon cancer.
S. Watson, D. Michaeli, S. Grimes, T. Morris +4 more
1996Cancer Research112 citations
Semantic Scholar
Faecal calprotectin levels in a high risk population for colorectal neoplasia
O. Kronborg, M. Ugstad, P. Fuglerud, B. Johne +5 more
2000Gut99 citations Open access
Semantic Scholar
Colorectal adenomas and diet: a case-control study of subjects participating in the Nottingham faecal occult blood screening programme.
Julian Little, R. Logan, P. G. Hawtin, J. Hardcastle +1 more
1993British Journal of Cancer78 citations Open access
Semantic Scholar
Psychiatric morbidity and screening for colorectal cancer
M. Parker, M. Robinson, J. Scholefield, J. Hardcastle
2002Journal of Medical Screening66 citations Open access
Semantic Scholar
Population screening for colorectal cancer: Comparison between guaiac and immunological faecal occult blood tests
M. Robinson, C. G. Marks, P. Farrands, W. Thomas +1 more
1994British Journal of Surgery64 citations
Semantic Scholar
Endoscopic screening of relatives of patients with colorectal cancer
L. Hunt, P. Rooney, J. Hardcastle, N. Armitage
1998Gut46 citations Open access
Semantic Scholar
An idiotypic replica of carcinoembryonic antigen inducing cellular and humoral responses directed against human colorectal tumours
L. Durrant, G. Denton, E. Jacobs, M. Mee +5 more
1992International Journal of Cancer46 citations
Semantic Scholar
Five‐year prospective study of DNA tumor ploidy and colorectal cancer survival
Mark A. S. Chapman, J. Hardcastle, N. Armitage
1995Cancer44 citations Open access
Semantic Scholar
The management of acute sigmoid volvulus in Nottingham.
D. Baker, P. Wardrop, H. Burrell, J. Hardcastle
1994Journal of the Royal College of Surgeons of Edinburgh41 citations
Semantic Scholar
Ki‐ras MUTATIONS IN ADENOMAS: A CHARACTERISTIC OF CANCER‐BEARING COLORECTAL MUCOSA
Robert G. Morris, L. Curtis, P. Romanowski, J. Hardcastle +4 more
1996Journal of Pathology40 citations
Semantic Scholar
The effect of calcium supplements on rectal mucosal proliferation.
N. Armitage, P. Rooney, K. Gifford, P. Clarke +1 more
1995British Journal of Cancer38 citations Open access
Semantic Scholar
Colorectal cancer screening and quality of life
D. Whynes, A. Neilson, M. Robinson, J. Hardcastle
1994Quality of Life Research37 citations
Semantic Scholar
Anti‐gastrin antibodies raised by gastrimmune inhibit growth of the human colorectal tumour AP5
Susan A. Watson, D. Michaeli, S. Grimes, T. Morris +6 more
1995International Journal of Cancer35 citations
Semantic Scholar
Screening of average-risk individuals for colorectal cancer. WHO Collaborating Centre for the Prevention of Colorectal Cancer.
S. Winawer, J. St. John, John H. Bond, J. Hardcastle +4 more
1990Bulletin of the World Health Organization34 citations
Semantic Scholar
Expression of CCKB/gastrin receptor isoforms in gastro‐intestinal tumour cells
S. Watson, P. Clarke, Andrew M. Smith, A. Varró +4 more
1998International Journal of Cancer32 citations Open access
Semantic Scholar
Two phase III trials of tauromustine (TCNU) in advanced colorectal cancer.
John F. Smyth, J. Hardcastle, G. Denton, D. Alderson +6 more
1995Annals of Oncology32 citations Open access
Semantic Scholar
A prospective evaluation of the effect of tumor cell DNA content on recurrence in colorectal cancer
N. Armitage, K. C. Ballantyne, P. Clarke, D. Evans +2 more
1991Cancer30 citations Open access
Semantic Scholar
Pre‐clinical evaluation of the Gastrimmune immunogen alone and in combination with 5‐fluorouracil/leucovorin in a rat colorectal cancer model
Susan A. Watson, Dov Michael, T. Justin, S. Grimes +4 more
1998International Journal of Cancer29 citations Open access
Semantic Scholar
Screening for colorectal carcinoma: An analysis of the sensitivity of Haemoccult
W. Thomas, G. Pye, J. Hardcastle, A. Walker
1992British Journal of Surgery29 citations
Semantic Scholar
Alkaline gastro-oesophageal reflux: dual probe pH monitoring.
S. Iftikhar, Sally Ledingham, D. Evans, S. Yusuf +3 more
1995Gut28 citations Open access
Semantic Scholar
Gastric carcinoid expresses the gastrin autocrine pathway
A. Smith, Susan A. Watson, M. Caplin, P. Clarke +3 more
1998British Journal of Surgery26 citations
Semantic Scholar
A hepatic invasive human colorectal xenograft model.
Susan A. Watson, T. Morris, David M. Crosbee, J. Hardcastle
1993European Journal of Cancer25 citations
Semantic Scholar
Change towards earlier stage at presentation of colorectal cancer
Michael Robinson, W. Thomas, J. Hardcastle, J. Chamberlain +1 more
1993British Journal of Surgery23 citations
Semantic Scholar
Role of dietary restriction in Haemoccult® screening for colorectal cancer
W. Thomas, G. Pye, J. Hardcastle, J. Chamberlain +1 more
1989British Journal of Surgery23 citations
Semantic Scholar
Comparison of coloscreen self‐test® and Haemoccult® faecal occult blood tests in the detection of colorectal cancer in symptomatic patients
G. Pye, J. Jackson, W. Thomas, J. Hardcastle
1990British Journal of Surgery21 citations
Semantic Scholar
Biodistribution of a monoclonal antibody‐methotrexate conjugate (791T/36‐MTX) in patients with colorectal cancer
K. C. Ballantyne, A. Perkins, M. Pimm, M. Garnett +4 more
1988International journal of cancer. Supplement = Journal international du cancer. Supplement21 citations
Semantic Scholar
How often is a positive faecal occult blood test the result of coeliac disease?
R. Logan, G. Howarth, J. West, Kate Shepherd +2 more
2003European Journal of Gastroenterology and Hepathology19 citations
Semantic Scholar
Screening for colorectal cancer with an immunological faecal occult blood test: 2‐Year follow‐up
M. Robinson, C. G. Marks, P. Farrands, K. Bostock +1 more
1996British Journal of Surgery19 citations
Semantic Scholar
Intraoperative testing of anastomotic integrity after stapled anterior resection for cancer.
C. Griffith, J. Hardcastle
1990Journal of the Royal College of Surgeons of Edinburgh19 citations
Semantic Scholar
Predeposit autologous blood transfusion in patients with colorectal cancer: A feasibility study
S. Harrison, Robert J. C. Steele, A. K. Johnston, J. Jones +2 more
1992British Journal of Surgery18 citations
Semantic Scholar
A comparison of an anti‐gastrin antibody and cytotoxic drugs in the therapy of human gastric ascites in SCID mice
S. Watson, D. Michaeli, S. Grimes, T. Morris +5 more
1999International Journal of Cancer17 citations Open access
Semantic Scholar
Cost savings in mass population screening for colorectal cancer resulting from the early detection and excision of adenomas.
D. Whynes, Andrew R. Walker, J. Hardcastle
1992Health Economics16 citations
Semantic Scholar
Effect of subject age on costs of screening for colorectal cancer.
D. Whynes, Arthur Walker, J. Hardcastle
1992Journal of Epidemiology and Community Health15 citations Open access
Semantic Scholar
Trends in Incidence and Mortality
J. Hardcastle
199314 citations
Semantic Scholar
Hartmann's Procedure: An Appraisal
R. Whiston, N. Armitage, D. Wilcox, J. Hardcastle
1993Journal of the Royal Society of Medicine14 citations Open access
Semantic Scholar
Rehydration of guaiac-based faecal occult blood tests in mass screening for colorectal cancer. An economic perspective.
A. Walker, D. Whynes, J. Hardcastle
1991Scandinavian Journal of Gastroenterology14 citations
Semantic Scholar
Wheat fibre, lactulose and rectal mucosal proliferation in individuals with a family history of colorectal cancer
P. Rooney, L. Hunt, P. Clarke, K. Gifford +2 more
1994British Journal of Surgery13 citations
Semantic Scholar
Differential expression of the lewis Y antigen defined by monoclonal antibody C14/1/46/10 in colonic polyps
A. Waldock, Ian O. Ellis, N. Armitage, D. Turner +2 more
1989Cancer13 citations Open access
Semantic Scholar
Asymptomatic Colorectal Neoplasia and Fecal Characteristics
J. Little, R. Owen, F. Fernandez, P. G. Hawtin +4 more
2002Diseases of the Colon & Rectum12 citations
Semantic Scholar
Renal colic: A diagnostic and therapeutic review
A. Holdgate, J. Hardcastle
199912 citations
Semantic Scholar
Individuals with a strong family history of colorectal cancer demonstrate abnormal rectal mucosal proliferation
P. Rooney, M. Robinson, P. Clarke, J. Hardcastle +1 more
1993British Journal of Surgery12 citations
Semantic Scholar
Screening for colorectal cancer: A critical review
J. Hardcastle, G. Pye
2005World Journal of Surgery10 citations
Semantic Scholar
Screening high-risk groups for colorectal neoplasia.
J. Hardcastle, T. Justin
1996American Journal of Gastroenterology10 citations
Semantic Scholar
Summary of a working party on the surveillance of premalignant lesions.
A. Axon, P. Boyle, R. Riddell, S. Grandjouan +2 more
1994American Journal of Gastroenterology10 citations
Semantic Scholar

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