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M. Morbidelli · SciRah

Researcher profile · Semantic Scholar

M. Morbidelli

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M. Morbidelli — researcher profile on SciRah

h-index: 78
Works: 808
Citations: 24K

Most-cited papers

Perfusion mammalian cell culture for recombinant protein manufacturing - A critical review.
Jean-Marc Bielser, Moritz K. F. Wolf, J. Souquet, H. Broly +1 more
2018Biotechnology Advances237 citations Open access
Semantic Scholar
Bioprocessing in the Digital Age: The Role of Process Models
H. Narayanan, Martin F. Luna, Moritz Stosch, M. N. Cruz Bournazou +4 more
2019Biotechnology Journal218 citations Open access
Semantic Scholar
Bottle-grade polyethylene furanoate from ring-opening polymerisation of cyclic oligomers
Jan-Georg Rosenboom, Diana Kay Hohl, P. Fleckenstein, G. Storti +1 more
2018Nature Communications183 citations Open access
Semantic Scholar
Current trends in the production of biodegradable bioplastics: The case of polyhydroxyalkanoates.
João Medeiros Garcia Alcântara, Francesco Distante, G. Storti, D. Moscatelli +2 more
2020Biotechnology Advances113 citations Open access
Semantic Scholar
A new generation of predictive models: The added value of hybrid models for manufacturing processes of therapeutic proteins
H. Narayanan, M. Sokolov, M. Morbidelli, A. Butté
2019Biotechnology and Bioengineering109 citations
Semantic Scholar
Hybrid‐EKF: Hybrid model coupled with extended Kalman filter for real‐time monitoring and control of mammalian cell culture
H. Narayanan, Lars Behle, Martin F. Luna, M. Sokolov +3 more
2020Biotechnology and Bioengineering76 citations Open access
Semantic Scholar
Oligonucleotides: Current trends and innovative applications in the synthesis, characterization and purification.
M. Catani, Chiara De Luca, João Medeiros Garcia Alcântara, Nicolò Manfredini +7 more
2020Biotechnology Journal62 citations Open access
Semantic Scholar
Hybrid modeling for biopharmaceutical processes: advantages, opportunities, and implementation
H. Narayanan, M. von Stosch, F. Feidl, M. Sokolov +2 more
2023Frontiers in Chemical Engineering60 citations Open access
Semantic Scholar
Hybrid Models for the simulation and prediction of chromatographic processes for protein capture.
H. Narayanan, Toby Seidler, Martin F. Luna, M. Sokolov +2 more
2021Journal of Chromatography A60 citations Open access
Semantic Scholar
Sequential Multivariate Cell Culture Modeling at Multiple Scales Supports Systematic Shaping of a Monoclonal Antibody Toward a Quality Target.
M. Sokolov, M. Morbidelli, A. Butté, J. Souquet +1 more
2018Biotechnology Journal58 citations
Semantic Scholar
A new flow cell and chemometric protocol for implementing in‐line Raman spectroscopy in chromatography
F. Feidl, Simone Garbellini, Sebastian Vogg, M. Sokolov +4 more
2019Biotechnology progress (Print)56 citations
Semantic Scholar
Guaiacol hydrodeoxygenation as a model for lignin upgrading. Role of the support surface features on Ni-based alumina-silica catalysts
F. Broglia, L. Rimoldi, D. Meroni, S. De Vecchi +2 more
2019Fuel55 citations
Semantic Scholar
Integration and digitalization in the manufacturing of therapeutic proteins
H. Narayanan, Mattia Sponchioni, M. Morbidelli
2022Chemical Engineering and Science53 citations
Semantic Scholar
Understanding mAb aggregation during low pH viral inactivation and subsequent neutralization
Ruben Wälchli, Mariana Ressurreição, Sebastian Vogg, F. Feidl +8 more
2019Biotechnology and Bioengineering52 citations
Semantic Scholar
Modern trends in downstream processing of biotherapeutics through continuous chromatography: The potential of Multicolumn Countercurrent Solvent Gradient Purification
Chiara De Luca, Simona Felletti, Giulio Lievore, T. Chenet +4 more
2020Trends in Analytical Chemistry (TrAC)51 citations Open access
Semantic Scholar
Development of a shake tube‐based scale‐down model for perfusion cultures
Moritz K. F. Wolf, V. Lorenz, D. Karst, J. Souquet +2 more
2018Biotechnology and Bioengineering51 citations
Semantic Scholar
Hybrid Models Based on Machine Learning and an Increasing Degree of Process Knowledge: Application to Capture Chromatographic Step
H. Narayanan, Martin F. Luna, M. Sokolov, P. Arosio +2 more
2021Industrial & Engineering Chemistry Research48 citations Open access
Semantic Scholar
Improved Performance in Mammalian Cell Perfusion Cultures by Growth Inhibition
Moritz K. F. Wolf, Aurélie Closet, Monika Bzowska, Jean-Marc Bielser +3 more
2018Biotechnology Journal48 citations Open access
Semantic Scholar
Perfusion cell culture for the production of conjugated recombinant fusion proteins reduces clipping and quality heterogeneity compared to batch-mode processes.
Jean-Marc Bielser, Loïc Chappuis, Yashi Xiao, J. Souquet +2 more
2019Journal of Biotechnology45 citations
Semantic Scholar
Hybrid Models Based on Machine Learning and an Increasing Degree of Process Knowledge: Application to Cell Culture Processes
H. Narayanan, Martin F. Luna, M. Sokolov, A. Butté +1 more
2022Industrial & Engineering Chemistry Research44 citations
Semantic Scholar
Combining Mechanistic Modeling and Raman Spectroscopy for Monitoring Antibody Chromatographic Purification
F. Feidl, Simone Garbellini, Martin F. Luna, Sebastian Vogg +4 more
2019Processes43 citations Open access
Semantic Scholar
Current status and future challenges in continuous biochromatography
Sebastian Vogg, Thomas Müller-Späth, M. Morbidelli
2018Current Opinion in Chemical Engineering43 citations
Semantic Scholar
From batch to continuous chromatographic purification of a therapeutic peptide through multicolumn countercurrent solvent gradient purification.
Chiara De Luca, Simona Felletti, Giulio Lievore, A. Buratti +7 more
2020Journal of Chromatography A40 citations Open access
Semantic Scholar
Semi‐continuous scale‐down models for clone and operating parameter screening in perfusion bioreactors
Jean-Marc Bielser, Jakub Domaradzki, J. Souquet, H. Broly +1 more
2019Biotechnology progress (Print)38 citations
Semantic Scholar
Effect of SiO2 Nanoparticles on the Performance of PVdF-HFP/Ionic Liquid Separator for Lithium-Ion Batteries
S. Caimi, Antoine Klaue, Hua Wu, M. Morbidelli
2018Nanomaterials38 citations Open access
Semantic Scholar
Model assisted comparison of Protein A resins and multi-column chromatography for capture processes.
Daniel Baur, J. Angelo, S. Chollangi, Xuan-Kuo Xu +5 more
2018Journal of Biotechnology38 citations
Semantic Scholar
Decision Tree‐PLS (DT‐PLS) algorithm for the development of process: Specific local prediction models
H. Narayanan, M. Sokolov, A. Butté, M. Morbidelli
2019Biotechnology progress (Print)36 citations
Semantic Scholar
Biotechnology and Bioengineering
Moritz K. F. Wolf, Andrea Müller, J. Souquet, H. Broly +1 more
201936 citations
Semantic Scholar
Continuous Biopharmaceutical Processes
D. Pfister, Lucrèce Nicoud, M. Morbidelli
201835 citations Open access
Semantic Scholar
Modeling the nonlinear behavior of a bioactive peptide in reversed-phase gradient elution chromatography.
Chiara De Luca, Simona Felletti, Marco Macis, W. Cabri +7 more
2019Journal of Chromatography A32 citations Open access
Semantic Scholar
Design space and robustness analysis of batch and counter-current frontal chromatography processes for the removal of antibody aggregates.
Sebastian Vogg, Thomas Müller-Späth, M. Morbidelli
2020Journal of Chromatography A30 citations
Semantic Scholar
Cell culture process metabolomics together with multivariate data analysis tools opens new routes for bioprocess development and glycosylation prediction
P. Zürcher, M. Sokolov, David Brühlmann, Raphael Ducommun +6 more
2020Biotechnology progress (Print)30 citations
Semantic Scholar
A two-step procedure for the design of perfusion bioreactors
Moritz K. F. Wolf, Anna Pechlaner, V. Lorenz, D. Karst +3 more
2019Biochemical engineering journal30 citations Open access
Semantic Scholar
Model‐assisted process characterization and validation for a continuous two‐column protein A capture process
Daniel Baur, J. Angelo, S. Chollangi, Thomas Müller-Späth +4 more
2018Biotechnology and Bioengineering30 citations Open access
Semantic Scholar
Insight into the Synthesis Process of an Industrial Ziegler–Natta Catalyst
Antoine Klaue, Matthias Kruck, Nic Friederichs, F. Bertola +2 more
2019Industrial & Engineering Chemistry Research28 citations Open access
Semantic Scholar
Expansion processes for cell-based therapies.
Ernesto Scibona, M. Morbidelli
2019Biotechnology Advances24 citations
Semantic Scholar
Proteomic analysis of micro-scale bioreactors as scale-down model for a mAb producing CHO industrial fed-batch platform.
Vania Bertrand, Sebastian Vogg, T. Villiger, Matthieu Stettler +3 more
2018Journal of Biotechnology22 citations
Semantic Scholar
Core-Shell Morphology of Redispersible Powders in Polymer-Cement Waterproof Mortars
S. Caimi, Elias Timmerer, M. Banfi, G. Storti +1 more
2018Polymers21 citations Open access
Semantic Scholar
Model based strategies towards protein A resin lifetime optimization and supervision.
F. Feidl, Martin F. Luna, Matevz Podobnik, Sebastian Vogg +8 more
2020Journal of Chromatography A20 citations Open access
Semantic Scholar
Polyacrylonitrile Nanoparticle‐Derived Hierarchical Structure for CO2 Capture
Anna Beltzung, Antoine Klaue, C. Colombo, Hua Wu +2 more
201819 citations
Semantic Scholar
Experimental Design of the Multicolumn Countercurrent Solvent Gradient Purification (MCSGP) Unit for the Separation of PEGylated Proteins
Tae Keun Kim, C. Botti, J. Angelo, Xuan-Kuo Xu +4 more
2021Industrial & Engineering Chemistry Research18 citations Open access
Semantic Scholar
Calixarene-immobilized monolithic cryogels for preparative protein chromatography.
Idris Guven, O. Gezici, M. Bayrakci, M. Morbidelli
2018Journal of Chromatography A18 citations Open access
Semantic Scholar
Process Intensification for the Purification of Peptidomimetics: The Case of Icatibant through Multicolumn Countercurrent Solvent Gradient Purification (MCSGP)
Chiara De Luca, Simona Felletti, D. Bozza, Giulio Lievore +7 more
202117 citations
Semantic Scholar
Biotechnology and Bioengineering
Vania Bertrand, D. Karst, A. Bachmann, Katia Cantalupo +2 more
201917 citations
Semantic Scholar
Synthesis of Cyclic (Ethylene Furanoate) Oligomers via Cyclodepolymerization
P. Fleckenstein, Jan-Georg Rosenboom, G. Storti, M. Morbidelli
201817 citations
Semantic Scholar
Experimental Evaluation of the Impact of Intrinsic Process Parameters on the Performance of a Continuous Chromatographic Polishing Unit (MCSGP).
Sebastian Vogg, Nicole Ulmer, J. Souquet, H. Broly +1 more
2019Biotechnology Journal16 citations
Semantic Scholar
Effect of the charge interactions on the composition behavior of acrylamide/acrylic acid copolymerization in aqueous medium
Eric J. Fischer, D. Cuccato, G. Storti, M. Morbidelli
201815 citations Open access
Semantic Scholar
Reaction kinetics and simulations of ring-opening polymerization for the synthesis of polybutylene terephthalate
Jan-Georg Rosenboom, Laura De Lorenzi, G. Storti, M. Morbidelli
2018Polymer14 citations Open access
Semantic Scholar
Analysis and optimal design of batch and two‐column continuous chromatographic frontal processes for monoclonal antibody purification
Ce Shi, Sebastian Vogg, Dong-Qiang Lin, Mattia Sponchioni +1 more
2020Biotechnology and Bioengineering13 citations Open access
Semantic Scholar
Perfusion Cell Culture Processes for Biopharmaceuticals
Moritz K. F. Wolf, Jean-Marc Bielser, M. Morbidelli
202012 citations
Semantic Scholar

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J. Souquet×13
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A. Butté×13
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M. Sokolov×11
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M. Catani — researcher profile on SciRah