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Y. Peterson · SciRah

Researcher profile · Semantic Scholar

Y. Peterson

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Y. Peterson — researcher profile on SciRah

h-index: 29
Works: 71
Citations: 3,297

Most-cited papers

The Diverse Roles of Arrestin Scaffolds in G Protein–Coupled Receptor Signaling
Y. Peterson, L. Luttrell
2017Pharmacological Reviews398 citations Open access
Semantic Scholar
Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis
S. Saddoughi, S. Gencer, Y. Peterson, Katherine E. Ward +15 more
2012EMBO Molecular Medicine275 citations Open access
Semantic Scholar
Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo.
M. Gotta, Yan Dong, Y. Peterson, S. M. Lanier +1 more
2003Current Biology259 citations Open access
Semantic Scholar
The conformational signature of arrestin3 predicts its trafficking and signaling functions
Mi-Hye Lee, K. Appleton, Erik G. Strungs, Joshua Kwon +4 more
2016Nature169 citations Open access
Semantic Scholar
Selective Interaction of AGS3 with G-proteins and the Influence of AGS3 on the Activation State of G-proteins*
Michael L. Bernard, Y. Peterson, Peter Chung, J. Jourdan +1 more
2001Journal of Biological Chemistry148 citations Open access
Semantic Scholar
Quantitative Analysis of Mitochondrial Morphology and Membrane Potential in Living Cells Using High-Content Imaging, Machine Learning, and Morphological Binning
A. Leonard, R. Cameron, J. Speiser, B. Wolf +4 more
2014Biochimica et Biophysica Acta144 citations Open access
Semantic Scholar
Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation
S. Selvam, R. DePalma, Joshua J. Oaks, N. Oleinik +7 more
2015Science Signaling135 citations Open access
Semantic Scholar
Stabilization of the GDP-bound Conformation of Giα by a Peptide Derived from the G-protein Regulatory Motif of AGS3*
Y. Peterson, Michael L. Bernard, Hongzheng Ma, S. Hazard +2 more
2000Journal of Biological Chemistry135 citations Open access
Semantic Scholar
Characterization of Isoenzyme-Selective Inhibitors of Human Sphingosine Kinases
P. Gao, Y. Peterson, Ryan A. Smith, Charles D. Smith
2012PLoS ONE113 citations Open access
Semantic Scholar
AGS3 Inhibits GDP Dissociation from Gα Subunits of the Gi Family and Rhodopsin-dependent Activation of Transducin*
M. Natochin, B. Lester, Y. Peterson, Michael L. Bernard +2 more
2000Journal of Biological Chemistry104 citations Open access
Semantic Scholar
The β2-Adrenoceptor Agonist Formoterol Stimulates Mitochondrial Biogenesis
Lauren P. Wills, Richard E. Trager, G. Beeson, Christopher C. Lindsey +3 more
2012Journal of Pharmacology and Experimental Therapeutics100 citations Open access
Semantic Scholar
Development of Allosteric Hydrazide-Containing Class I Histone Deacetylase Inhibitors for Use in Acute Myeloid Leukemia
Jesse J. McClure, Cheng Zhang, Elizabeth S. Inks, Y. Peterson +2 more
2016Journal of Medicinal Chemistry83 citations Open access
Semantic Scholar
The Chemical Relationship Among Beta-Lactam Antibiotics and Potential Impacts on Reactivity and Decomposition
Jonathan W Turner, Alyssa K Muraoka, Michael Bedenbaugh, Blaine C. Childress +3 more
2022Frontiers in Microbiology77 citations Open access
Semantic Scholar
Receptor- and Nucleotide Exchange-independent Mechanisms for Promoting G Protein Subunit Dissociation*
M. Ghosh, Y. Peterson, S. M. Lanier, A. Smrcka
2003Journal of Biological Chemistry73 citations Open access
Semantic Scholar
Class I HDAC Inhibitors Display Different Antitumor Mechanism in Leukemia and Prostatic Cancer Cells Depending on Their p53 Status
Xiao-Yang Li, Y. Peterson, Elizabeth S. Inks, Richard A. Himes +4 more
2018Journal of Medicinal Chemistry69 citations Open access
Semantic Scholar
A Novel Protein Geranylgeranyltransferase-I Inhibitor with High Potency, Selectivity, and Cellular Activity*
Y. Peterson, P. Kelly, C. Weinbaum, P. Casey
2006Journal of Biological Chemistry68 citations Open access
Semantic Scholar
Interaction of Activator of G-protein Signaling 3 (AGS3) with LKB1, a Serine/Threonine Kinase Involved in Cell Polarity and Cell Cycle Progression
J. Blumer, Michael L. Bernard, Y. Peterson, J. Nezu +4 more
2003Journal of Biological Chemistry63 citations Open access
Semantic Scholar
Identification of selected therapeutic agents as inhibitors of carboxylesterase 1: potential sources of metabolic drug interactions.
Hao-Jie Zhu, D. I. Appel, Y. Peterson, Zichao Wang +1 more
2010Toxicology60 citations
Semantic Scholar
The Arrestin-selective Angiotensin AT1 Receptor Agonist [Sar1,Ile4,Ile8]-AngII Negatively Regulates Bradykinin B2 Receptor Signaling via AT1-B2 Receptor Heterodimers*
Parker C Wilson, Mi-Hye Lee, K. Appleton, H. El-Shewy +4 more
2013Journal of Biological Chemistry56 citations Open access
Semantic Scholar
Design of hydrazide-bearing HDACIs based on panobinostat and their p53 and FLT3-ITD dependency in anti-leukemia activity
Xiao-Yang Li, Yu-Qi Jiang, Y. Peterson, Tong-Qiang Xu +8 more
2020Journal of Medicinal Chemistry54 citations Open access
Semantic Scholar
Identification of Structural Features in the G-protein Regulatory Motif Required for Regulation of Heterotrimeric G-proteins*
Y. Peterson, S. Hazard, S. Graber, S. M. Lanier
2002Journal of Biological Chemistry51 citations Open access
Semantic Scholar
Bax and Bcl-xL exert their regulation on different sites of the ceramide channel.
Meenu N. Perera, Shang H. Lin, Y. Peterson, A. Bielawska +3 more
2012Biochemical Journal49 citations
Semantic Scholar
Comparison of the Deacylase and Deacetylase Activity of Zinc-Dependent HDACs
Jesse J. McClure, Elizabeth S. Inks, Cheng Zhang, Y. Peterson +6 more
2017ACS Chemical Biology44 citations Open access
Semantic Scholar
Structural and pharmacological basis for the induction of mitochondrial biogenesis by formoterol but not clenbuterol
R. Cameron, Y. Peterson, C. Beeson, R. Schnellmann
2017Scientific Reports39 citations Open access
Semantic Scholar
The Discovery of Geranylgeranyltransferase-I Inhibitors with Novel Scaffolds by the Means of Quantitative Structure-Activity Relationship Modeling, Virtual Screening, and Experimental Validation
Y. Peterson, X. Wang, P. Casey, A. Tropsha
2009Journal of Medicinal Chemistry38 citations Open access
Semantic Scholar
Prediction and In Vitro Evaluation of Selected Protease Inhibitor Antiviral Drugs as Inhibitors of Carboxylesterase 1: A Potential Source of Drug-Drug Interactions
J. A. Rhoades, Y. Peterson, Hao-Jie Zhu, D. I. Appel +2 more
2012Pharmaceutical Research34 citations
Semantic Scholar
High-Throughput Screening for Novel Inhibitors of Neisseria gonorrhoeae Penicillin-Binding Protein 2
A. Fedarovich, Kevin A. Djordjevic, Shauna M. Swanson, Y. Peterson +2 more
2012PLoS ONE31 citations Open access
Semantic Scholar
Frizzled-5: A High Affinity Receptor for Secreted Frizzled-Related Protein-2 Activation of Nuclear Factor of Activated T-Cells c3 Signaling to Promote Angiogenesis
Y. Peterson, Patrick Nasarre, Ingrid V Bonilla, Eleanor G. Hilliard +4 more
2017Angiogenesis30 citations Open access
Semantic Scholar
Genetic variants of VEGFA and FLT4 are determinants of survival in renal cell carcinoma patients treated with sorafenib
D. Crona, A. Skol, Veli-Matti Leppänen, Dylan M Glubb +7 more
2018Cancer Research29 citations Open access
Semantic Scholar
Receptor-interacting Ser/Thr kinase 1 (RIPK1) and myosin IIA–dependent ceramidosomes form membrane pores that mediate blebbing and necroptosis
Rose Nganga, N. Oleinik, Jisun Kim, S. Selvam +11 more
2018Journal of Biological Chemistry28 citations Open access
Semantic Scholar
β2-adrenoceptor agonists in the regulation of mitochondrial biogenesis
Y. Peterson, R. Cameron, Lauren P. Wills, Richard E. Trager +3 more
2013Bioorganic & Medicinal Chemistry Letters28 citations Open access
Semantic Scholar
Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis
Alhaji H. Janneh, M. Kassir, F. C. Atilgan, H. Lee +15 more
2022Cell Reports27 citations Open access
Semantic Scholar
High-throughput respirometric assay identifies predictive toxicophore of mitochondrial injury
Lauren P. Wills, G. Beeson, Richard E. Trager, Christopher C. Lindsey +3 more
2013Toxicology and Applied Pharmacology25 citations Open access
Semantic Scholar
Biasing the parathyroid hormone receptor: relating in vitro ligand efficacy to in vivo biological activity.
K. Appleton, Mi-Hye Lee, Christian Alele, Christine Alele +4 more
2013Methods in Enzymology25 citations
Semantic Scholar
Suppression of GNAI2 message in ovarian cancer
John R. Jr Raymond, K. Appleton, J. Y. Pierce, Y. Peterson
2014Journal of Ovarian Research23 citations Open access
Semantic Scholar
Time-dependent inhibition of isoprenylcysteine carboxyl methyltransferase by indole-based small molecules.
R. Baron, Y. Peterson, J. Otto, J. Rudolph +1 more
2007Biochemistry22 citations
Semantic Scholar
Small molecules targeting the NADH-binding pocket of VDAC modulate mitochondrial metabolism in hepatocarcinoma cells
Kareem A. Heslop, P. Burger, Christiana S. Kappler, A. K. Solanki +7 more
2022Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie21 citations Open access
Semantic Scholar
Effects of pharmacologic inhibition of protein geranylgeranyltransferase type I on aqueous humor outflow through the trabecular meshwork.
P. Rao, Y. Peterson, Toshihiro Inoue, P. Casey
2008Investigative Ophthalmology and Visual Science20 citations Open access
Semantic Scholar
Influence of cytosolic AGS3 on receptor--G protein coupling.
Hongzheng Ma, Y. Peterson, Michael L. Bernard, S. M. Lanier +1 more
2003Biochemistry18 citations
Semantic Scholar
Development of inhibitors of heterotrimeric Gαi subunits
K. Appleton, Kevin J. Bigham, Christopher C. Lindsey, S. Hazard +4 more
2014Bioorganic & Medicinal Chemistry17 citations Open access
Semantic Scholar
Dual inhibitors of LSD1 and spermine oxidase.
Steven L. Holshouser, Matthew Dunworth, Tracy Murray-Stewart, Y. Peterson +5 more
2019MedChemComm16 citations Open access
Semantic Scholar
Selective targeting of CD38 hydrolase and cyclase activity as an approach to immunostimulation
Thomas Z. Benton, Catherine M. Mills, J. Turner, Megan J. Francis +6 more
2021RSC Advances13 citations Open access
Semantic Scholar
A human iPSC-derived hepatocyte screen identifies compounds that inhibit production of Apolipoprotein B
Jui-Tung Liu, Caren Doueiry, Yu-Lin Jiang, Josef Blaszkiewicz +9 more
2023Communications Biology12 citations Open access
Semantic Scholar
Development of a Novel Humanized Monoclonal Antibody to Secreted Frizzled-Related Protein-2 that Inhibits Triple Negative Breast Cancer and Angiosarcoma Growth in vivo
Denise I. Garcia, Patrick Nasarre, Ingrid V Bonilla, Eleanor G. Hilliard +7 more
2019Annals of Surgical Oncology12 citations Open access
Semantic Scholar
A High-Content, Live-Cell, and Real-Time Approach to the Quantitation of Ligand-Induced β-Arrestin2 and Class A/Class B GPCR Mobilization
A. Leonard, K. Appleton, L. Luttrell, Y. Peterson
2013Microscopy and Microanalysis11 citations Open access
Semantic Scholar
Docking optimization, variance and promiscuity for large-scale drug-like chemical space using high performance computing architectures.
Richard E. Trager, Paul Giblock, Sherwin Soltani, Amit A. Upadhyay +2 more
2016Drug Discovery Today9 citations
Semantic Scholar
Hydrophilic Anilinogeranyl Diphosphate Prenyl Analogues Are Ras Function Inhibitors
M. J. Roberts, J. Troutman, K. Chehade, H. Cha +8 more
20069 citations
Semantic Scholar
Hydrophilic anilinogeranyl diphosphate prenyl analogues are Ras function inhibitors.
M. J. Roberts, J. Troutman, K. Chehade, H. Cha +8 more
2006Biochemistry8 citations
Semantic Scholar
Neuropilin-2b facilitates resistance to tyrosine kinase inhibitors in non–small cell lung cancer
A. Dimou, C. Nasarre, Y. Peterson, Rose Pagano +7 more
2020Journal of Thoracic and Cardiovascular Surgery7 citations Open access
Semantic Scholar
Extracorporeal Removal of Thermosensitive Liposomal Doxorubicin from Systemic Circulation after Tumor Delivery to Reduce Toxicities
Anjan Motamarry, A. M. Wolfe, K. Ramajayam, Sanket Pattanaik +6 more
2022Cancers5 citations Open access
Semantic Scholar

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