Jonatan Caroli

Most-cited papers

1. The scaffolding function of LSD1 controls DNA methylation in mouse ESCs

   Sandhya Malla, Kanchan Kumari, C. García-Prieto, Jonatan Caroli +21 more

   2024Nature Communications20 citations Open access

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2. Uncoupling Histone Modification Crosstalk by Engineering Lysine Demethylase LSD1

   Kwangwoon Lee, Marco Barone, Amanda L. Waterbury, Hanjie Jiang +13 more

   2024Nature Chemical Biology19 citations

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3. Fine-tuned KDM1A alternative splicing regulates human cardiomyogenesis through an enzymatic-independent mechanism

   V. Astro, G. Ramírez-Calderón, Roberta Pennucci, Jonatan Caroli +13 more

   2022iScience11 citations Open access

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4. Rationally Guided Improvement of NOV1 Dioxygenase for the Conversion of Lignin-Derived Isoeugenol to Vanillin

   M. De Simone, L. Alvigini, Lur Alonso-Cotchico, Vânia Brissos +6 more

   2022Biochemistry9 citations Open access

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5. Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity

   R. Fioravanti, V. Rodriguez, Jonatan Caroli, U. Chianese +10 more

   2022Journal of Enzyme Inhibition and Medicinal Chemistry6 citations Open access

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6. Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance

   Amanda L. Waterbury, Jonatan Caroli, Olivia Zhang, Paloma R. Tuttle +8 more

   2025Nature Communications5 citations Open access

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7. Uncovering a Mutation-Independent Therapeutic Strategy against Inherited Retinal Diseases: Development of Class I HDAC/LSD1 Hybrid Inhibitors.

   Gabriele Carullo, I. Piano, Giulia Salamone, Francesca Corsi +17 more

   2025ACS Chemical Neuroscience1 citations

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8. Tranylcypromine-Based LSD1 Inhibitors as Useful Agents to Reduce Viability of

   Emanuele Fabbrizi, G. Hailu, A. Ganesan, Rossella Fioravanti +12 more

   2025ACS Infectious Diseases1 citations Open access

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9. The catalytic-independent function of LSD1 modulates the epigenetic landscape of mouse embryonic stem cells

   Sandhya Malla, K. Kumari, Carlos Martinez-Gamero, C. García-Prieto +14 more

   2023bioRxiv1 citations Open access

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10. Evolution of human IL4I1 preference for aromatic amino acids from a broad-specificity L-amino acid oxidase ancestor.

    Marta Massari, Jonatan Caroli, Marco Malatesta, Sara Marchese +3 more

    2026Proceedings of the National Academy of Sciences of the United States of America0 citations Open access

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11. LSD1 serine 166 is a phosphorylation switch for chromatin landscaping, gene activation, and tissue remodeling

    Mukund Sharma, Anna Aakula, O. Denisova, E. Ceccacci +16 more

    2025bioRxiv0 citations Open access

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12. The NPAC-LSD2 complex in nucleosome demethylation.

    Jonatan Caroli, A. Mattevi

    2023The Enzymes0 citations

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