Researcher profile · Semantic Scholar

S. Shin

h-index: 21
Works: 36
Citations: 1,619

Most-cited papers

Resveratrol Protects Mitochondria against Oxidative Stress through AMP-Activated Protein Kinase-Mediated Glycogen Synthase Kinase-3β Inhibition Downstream of Poly(ADP-ribose)polymerase-LKB1 Pathway
S. Shin, I. Cho, S. G. Kim
2009Molecular Pharmacology213 citations
Semantic Scholar
Role of the Nrf2-ARE Pathway in Liver Diseases
S. Shin, Ji Hye Yang, S. Ki
2013Oxidative Medicine and Cellular Longevity209 citations Open access
Semantic Scholar
Isorhamnetin protects against oxidative stress by activating Nrf2 and inducing the expression of its target genes.
Ji Hye Yang, Bo-Ye-On Shin, Jae Yun Han, Mi Gwang Kim +6 more
2014Toxicology and Applied Pharmacology137 citations
Semantic Scholar
Role of sestrin2 in the regulation of proinflammatory signaling in macrophages.
Ji Hye Yang, Kyu Min Kim, Mi Gwang Kim, Kyuhwa Seo +7 more
2015Free Radical Biology & Medicine103 citations
Semantic Scholar
Methylglyoxal Induces Mitochondrial Dysfunction and Cell Death in Liver
Kyuhwa Seo, S. Ki, S. Shin
2014Toxicological Research91 citations Open access
Semantic Scholar
Inhibition of Arachidonic Acid and Iron-Induced Mitochondrial Dysfunction and Apoptosis by Oltipraz and Novel 1,2-Dithiole-3-thione Congeners
S. Shin, S. G. Kim
2009Molecular Pharmacology90 citations
Semantic Scholar
Resveratrol inhibits LXRα-dependent hepatic lipogenesis through novel antioxidant Sestrin2 gene induction.
So-Hee Jin, Ji Hye Yang, Bo-Ye-On Shin, Kyuhwa Seo +3 more
2013Toxicology and Applied Pharmacology88 citations
Semantic Scholar
The Antioxidant Effects of Isorhamnetin Contribute to Inhibit COX-2 Expression in Response to Inflammation: A Potential Role of HO-1
Kyuhwa Seo, Ji Hye Yang, Sang Chan Kim, S. Ku +2 more
2013Inflammation85 citations
Semantic Scholar
Regulation of Toll-like receptor-mediated Sestrin2 induction by AP-1, Nrf2, and the ubiquitin-proteasome system in macrophages.
Mi Gwang Kim, Ji Hye Yang, Kyu Min Kim, Chang-Ho Jang +4 more
2015Toxicological Sciences75 citations Open access
Semantic Scholar
Sestrin2-AMPK activation protects mitochondrial function against glucose deprivation-induced cytotoxicity.
Kyuhwa Seo, S. Ki, S. Shin
2015Cellular Signalling57 citations
Semantic Scholar
Functional Induction of P-glycoprotein in the Blood-Brain Barrier of Streptozotocin-Induced Diabetic Rats: Evidence for the Involvement of Nuclear Factor-κB, a Nitrosative Stress-Sensitive Transcription Factor, in the Regulation
H. Maeng, Mi-Hwa Kim, Hyo-Eon Jin, S. Shin +5 more
2007Drug Metabolism And Disposition57 citations
Semantic Scholar
Resveratrol attenuates methylglyoxal-induced mitochondrial dysfunction and apoptosis by Sestrin2 induction.
Kyuhwa Seo, Suho Seo, Jae Yun Han, S. Ki +1 more
2014Toxicology and Applied Pharmacology50 citations
Semantic Scholar
Sestrin2 inhibits hypoxia-inducible factor-1α accumulation via AMPK-mediated prolyl hydroxylase regulation.
Kyuhwa Seo, Suho Seo, S. Ki, S. Shin
2016Free Radical Biology & Medicine46 citations
Semantic Scholar
Isorhamnetin Inhibits Reactive Oxygen Species-Dependent Hypoxia Inducible Factor (HIF)-1α Accumulation.
Suho Seo, Kyuhwa Seo, S. Ki, S. Shin
2016Biological and Pharmaceutical Bulletin45 citations Open access
Semantic Scholar
Inhibitory Effect of Sestrin 2 on Hepatic Stellate Cell Activation and Liver Fibrosis
Ji Hye Yang, Kyu Min Kim, S. Cho, S. Shin +10 more
2019Antioxidants and Redox Signaling34 citations
Semantic Scholar
5-Fluorouracil inhibits cell migration by induction of Sestrin2 in colon cancer cells
Kyuhwa Seo, S. Ki, E. Park, S. Shin
2017Archives of pharmacal research27 citations
Semantic Scholar
Induction of Lipin1 by ROS-Dependent SREBP-2 Activation
Kyuhwa Seo, S. Shin
2017Toxicological Research26 citations Open access
Semantic Scholar
Sestrin2: A Promising Therapeutic Target for Liver Diseases.
Kyu Min Kim, Ji Hye Yang, S. Shin, I. Cho +1 more
2015Biological and Pharmaceutical Bulletin25 citations Open access
Semantic Scholar
Oxidized Metabolites of Oltipraz Exert Cytoprotective Effects against Arachidonic Acid through AMP-Activated Protein Kinase-Dependent Cellular Antioxidant Effect and Mitochondrial Protection
Young Nam Kwon, S. Shin, I. Cho, S. G. Kim
2009Drug Metabolism And Disposition25 citations
Semantic Scholar
Cudrania Tricuspidata Extract and Its Major Constituents Inhibit Oxidative Stress-Induced Liver Injury
S. Cho, Ji Hye Yang, Kyuhwa Seo, S. Shin +11 more
2019Journal of Medicinal Food24 citations
Semantic Scholar
meso-Dihydroguaiaretic Acid from Machilus thunbergii Down-Regulates TGF-β1 Gene Expression in Activated Hepatic Stellate Cells via Inhibition of AP-1 Activity
Eun Young Park, S. Shin, C. Ma, Y. Kim +1 more
2005Planta Medica24 citations
Semantic Scholar
Compound C Increases Sestrin2 Expression via Mitochondria-Dependent ROS Production.
Kyuhwa Seo, Suho Seo, S. Ki, S. Shin
2016Biological and Pharmaceutical Bulletin19 citations Open access
Semantic Scholar
The Role of Lipin-1 in the Regulation of Fibrogenesis and TGF-β Signaling in Hepatic Stellate Cells.
Chang-Ho Jang, Kyu Min Kim, Ji Hye Yang, S. Cho +4 more
2016Toxicological Sciences19 citations
Semantic Scholar
Synthesis of Novel FTY720 Analogs with Anticancer Activity through PP2A Activation
Jitendra Shrestha, S. Ki, S. Shin, Seon Woong Kim +6 more
2018Molecules15 citations Open access
Semantic Scholar
A Novel Mechanism of PPARγ Regulation of TGFβ1: Implication in Cancer Biology
C. Lee, Hyung Don Kim, S. Shin, S. G. Kim
2008PPAR Research15 citations Open access
Semantic Scholar
CCAAT/enhancer binding protein activation by PD98059 contributes to the inhibition of AhR-mediated 3-methylcholanthrene induction of CYP1A1
S. Shin, I. Cho, S. G. Kim
2005Xenobiotica; the fate of foreign compounds in biological systems6 citations
Semantic Scholar
Synthesis and Biological Evaluation of PF-543 Derivative Containing Aliphatic Side Chain.
Seon Woong Kim, Taeho Lee, Y. Oh, S. Shin +4 more
2019Chemical and pharmaceutical bulletin5 citations Open access
Semantic Scholar
Synthesis and Biological Evaluation of FTY720 (Fingolimod) Derivatives with Aromatic Head Group as Anticancer Agents.
Taeho Lee, H. Moon, Seon Woong Kim, Jitendra Shrestha +5 more
2018Chemical and pharmaceutical bulletin5 citations Open access
Semantic Scholar
Potential role of mitochondrial ROS in Sestrin2 degradation
Kyuhwa Seo, Suho Seo, S. Ki, S. Shin
2017Biotechnology and Bioprocess Engineering2 citations
Semantic Scholar
Synthesis of FTY720 (Fingolimod) Derivatives Containing Serine Structure
Y. Oh, Taeho Lee, S. Shin, Jitendra Shrestha +3 more
20181 citations
Semantic Scholar
5-Fluorouracil inhibits cell migration by induction of Sestrin2 in colon cancer cells
Kyuhwa Seo, S. Ki, E. Park, S. Shin
2016Archives of pharmacal research1 citations
Semantic Scholar
Oxidized Metabolites of Oltipraz Exert Cytoprotective Effects against Arachidonic Acid through AMPK-dependent Cellular Antioxidant Effect and Mitochondrial Protection
Young Nam Kwon, S. Shin, I. Cho, Ge-On Sang
20091 citations
Semantic Scholar
イソラムネチンは活性酸素種依存性の低酸素誘導因子(HIF)‐1α蓄積を阻害する
Suho Seo, Seo Kyuhwa, Ki Sung Hwan, S. Shin
20160 citations
Semantic Scholar
The AMPK activation by sauchinone, a Saururus chinensis lignan, enables hepatocytes to protect against the toxicity induced by iron overload
S. Shin, Young Woo Kim, Sang Geon Kim
20090 citations
Semantic Scholar
N,N-DIMETHYLFORAMIDE IN COMBINATION WITH CARBON TETRACHLORIDE PROMOTES HEPATIC INJURY WITH LIPID PEROXIDATION
Tae Hyun Kim, Youngwoo Kim, S. Shin, I. Yu +1 more
20090 citations
Semantic Scholar
Inhibition of arachidonic acid‐induced ER stress and mitochondrial dysfunction by novel dithiolethiones
S. Shin, Sang Geon Kim
20080 citations
Semantic Scholar

S. G. Kim

×8

Suho Seo×6

Kyu Min Kim×5

S. Ku×4

Taeho Lee×4

D. Baek×4

Eun-Young Park×4

Mi Gwang Kim×3