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Xiao-Xiang Chen · SciRah

Researcher profile · Semantic Scholar

Xiao-Xiang Chen

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Xiao-Xiang Chen — researcher profile on SciRah

h-index: 21
Works: 96
Citations: 2,657

Most-cited papers

Modulatory Effects of 1,25-Dihydroxyvitamin D3 on Human B Cell Differentiation
Shengde Chen, G. Sims, Xiao-Xiang Chen, Yue-Ying Gu +2 more
2007Journal of Immunology1,133 citations
Semantic Scholar
Hypoxia-inducible factor-1α is a critical transcription factor for IL-10-producing B cells in autoimmune disease
Xian-Yi Meng, Bettina Grötsch, Yu-Bin Luo, K. Knaup +6 more
2018Nature Communications254 citations Open access
Semantic Scholar
Adult clinically amyopathic dermatomyositis with rapid progressive interstitial lung disease: a retrospective cohort study
S. Ye, Xiao-Xiang Chen, Xiao-Ye Lu, Mei-fang Wu +7 more
2007Clinical Rheumatology225 citations Open access
Semantic Scholar
L-arginine metabolism inhibits arthritis and inflammatory bone loss
S. Cao, Yi-Xuan Li, R. Song, Xian-Yi Meng +15 more
2023Annals of the Rheumatic Diseases98 citations Open access
Semantic Scholar
Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthritis.
N. Hannemann, Shan Cao, D. Eriksson, A. Schnelzer +14 more
2019Journal of Clinical Investigation78 citations Open access
Semantic Scholar
Dynamic changes in serum IL-6, IL-8, and IL-10 predict the outcome of ICU patients with severe COVID-19.
Jia Li, L. Rong, R. Cui, Jiaqi Feng +3 more
2021Annals of Palliative Medicine53 citations Open access
Semantic Scholar
High fat diet increases melanoma cell growth in the bone marrow by inducing osteopontin and interleukin 6
Guang-Di Chen, Yu-Bin Luo, D. Eriksson, Xian-Yi Meng +5 more
2016OncoTarget48 citations Open access
Semantic Scholar
Anti-α-Internexin Autoantibody from Neuropsychiatric Lupus Induce Cognitive Damage via Inhibiting Axonal Elongation and Promote Neuron Apoptosis
Xiao-Ye Lu, Xiao-Xiang Chen, Li-Dong Huang, Chang-Qing Zhu +2 more
2010PLoS ONE44 citations Open access
Semantic Scholar
Signal Transducer and Activator of Transcription 3 Hyperactivation Associates With Follicular Helper T Cell Differentiation and Disease Activity in Rheumatoid Arthritis
Jun Deng, Chao-Fan Fan, Xin Gao, Qunxiong Zeng +18 more
2018Frontiers in Immunology42 citations Open access
Semantic Scholar
Increased expression of the type I interferon-inducible gene, lymphocyte antigen 6 complex locus E, in peripheral blood cells is predictive of lupus activity in a large cohort of Chinese lupus patients
J. Tang, Yue-Ying Gu, M. Zhang, S. Ye +6 more
2008Lupus37 citations
Semantic Scholar
Intratumor Heterogeneity Correlates With Reduced Immune Activity and Worse Survival in Melanoma Patients
Zhen Lin, Xian-Yi Meng, Jinming Wen, J. M. Corral +5 more
2020Frontiers in Oncology32 citations Open access
Semantic Scholar
Some Plasmin-Induced Antibodies Bind to Cardiolipin, Display Lupus Anticoagulant Activity and Induce Fetal Loss in Mice1
Xiao-Xiang Chen, Yue-Ying Gu, Shu-Jie Li, J. Qian +4 more
2007Journal of Immunology31 citations Open access
Semantic Scholar
Lymphocyte mass cytometry identifies a CD3-CD4+ cell subset with a potential role in psoriasis.
Ru-Ru Guo, Ting Zhang, Xin-Yu Meng, Zhen Lin +8 more
2019JCI Insight29 citations Open access
Semantic Scholar
Adipogenic niches for melanoma cell colonization and growth in bone marrow.
Juan-Juan Wang, Guang-Di Chen, Shan Cao, Ming-chun Zhao +3 more
2017Laboratory investigation; a journal of technical methods and pathology28 citations Open access
Semantic Scholar
Endothelial Response to Type I Interferon Contributes to Vasculopathy and Fibrosis and Predicts Disease Progression of Systemic Sclerosis
Hanlin Yin, O. Distler, Li-Chong Shen, Xiaojiang Xu +13 more
2023Arthritis & Rheumatology27 citations Open access
Semantic Scholar
Efficacy and safety of a selective URAT1 inhibitor SHR4640 in Chinese subjects with hyperuricemia: a randomized controlled phase II study.
Yanwei Lin, Xiao-Xiang Chen, Hui-Hua Ding, P. Ye +24 more
2021Rheumatology27 citations
Semantic Scholar
Sustained low‐dose interleukin‐2 therapy alleviates pathogenic humoral immunity via elevating the Tfr/Tfh ratio in lupus
Kaili Liang, Jing He, Yun-Bo Wei, Qunxiong Zeng +14 more
2021Clinical & Translational Immunology27 citations Open access
Semantic Scholar
DNaseI Protects against Paraquat-Induced Acute Lung Injury and Pulmonary Fibrosis Mediated by Mitochondrial DNA
Li Guo, Yu-Zhen Li, Yi Chen, Xiao-Xiang Chen +3 more
2015BioMed Research International26 citations Open access
Semantic Scholar
A Role for Receptor-Interacting Protein Kinase-1 in Neutrophil Extracellular Trap Formation in Patients with Systemic Lupus Erythematosus: a Preliminary Study
Ru-Ru Guo, Y. Tu, Shao-Wei Xie, Xue-Song Liu +4 more
2018Cellular Physiology and Biochemistry24 citations Open access
Semantic Scholar
Hypoxia‐inducible factor‐1α regulates the interleukin‐6 production by B cells in rheumatoid arthritis
Chao-Fan Fan, Jia Li, Yixuan Li, Yuyan Jin +10 more
2023Clinical & Translational Immunology23 citations Open access
Semantic Scholar
Bioinspired Rotation Microneedles for Accurate Transdermal Positioning and Ultraminimal-Invasive Biomarker Detection with Mechanical Robustness
Yi-Lin Cai, Shiyi Huang, Zhi-Nan Zhang, Jiazhen Zhang +3 more
2022Research23 citations Open access
Semantic Scholar
Clinical phenotypes and prognostic factors of adult-onset Still’s disease: data from a large inpatient cohort
Rui Li, Xiao-Lei Liu, Guangliang Chen, G. Tang +4 more
2021Arthritis Research & Therapy21 citations Open access
Semantic Scholar
A multicenter, randomized, double-blind clinical trial of combination therapy with Anbainuo, a novel recombinant human TNFRII:Fc fusion protein, plus methotrexate versus methotrexate alone or Anbainuo alone in Chinese patients with moderate to severe rheumatoid arthritis
Xiao-Xiang Chen, Qing Dai, A. Huang, Hua-xiang Wu +8 more
2012Clinical Rheumatology21 citations
Semantic Scholar
AOSD Endotypes based on immune cell profiles: patient stratification with hierarchical clustering analysis.
Ru-Ru Guo, Xue-Song Liu, Yixuan Li, Xin-Yu Meng +3 more
2022Rheumatology19 citations
Semantic Scholar
Bile Acids Elevated in Chronic Periaortitis Could Activate Farnesoid-X-Receptor to Suppress IL-6 Production by Macrophages
Shan Cao, Xin-Yu Meng, Yixuan Li, Li Sun +3 more
2021Frontiers in Immunology18 citations Open access
Semantic Scholar
Fra-2/AP-1 regulates melanoma cell metastasis by downregulating Fam212b
Guang-Di Chen, Rui Li, Xiao-Xiang Chen, Juan-Juan Wang +8 more
2020Cell Death and Differentiation18 citations Open access
Semantic Scholar
Low Circulating Monocytes Is in Parallel With Lymphopenia Which Predicts Poor Outcome in Anti-melanoma Differentiation-Associated Gene 5 Antibody-Positive Dermatomyositis-Associated Interstitial Lung Disease
Xia Lv, Yuyan Jin, Danting Zhang, Yixuan Li +7 more
2022Frontiers in Medicine17 citations Open access
Semantic Scholar
Epidemiology of Takayasu arteritis in Shanghai: A hospital‐based study and systematic review
Ying Sun, Mengmeng Yin, Li-Li Ma, X. Dai +44 more
2021International Journal of Rheumatic Diseases17 citations
Semantic Scholar
An on‐Demand Oxygen Nano‐vehicle Sensitizing Protein and Nucleic Acid Drug Augment Immunotherapy
Sidi Zhang, Xing-Hui Wang, Xiaojing Chen, Duohuo Shu +10 more
2025Advances in Materials16 citations
Semantic Scholar
Distinct Metabolism of Bone Marrow Adipocytes and their Role in Bone Metastasis
Yixuan Li, S. Cao, Anastasia Gaculenko, Yifan Zhan +2 more
2022Frontiers in Endocrinology16 citations Open access
Semantic Scholar
RIPK1 downregulation enhances neutrophil extracellular traps in psoriasis
Xin-Yu Meng, Ru-Ru Guo, Chao-Fan Fan, Yixuan Li +3 more
2022Advances in Dermatology and Allergology16 citations Open access
Semantic Scholar
Severe pulmonary arterial hypertension secondary to lupus in the emergency department: proactive intense care associated with a better short‐term survival
Yi Chen, Li Guo, Yu-Zhen Li, Guang-liang Chen +2 more
2015International Journal of Rheumatic Diseases16 citations Open access
Semantic Scholar
Low-dose imatinib in the treatment of severe systemic sclerosis: a case series of six Chinese patients and literature review
Li Guo, Xiao-Xiang Chen, Yue-Ying Gu, He-jian Zou +1 more
2012Clinical Rheumatology16 citations
Semantic Scholar
Associations between glucocorticoids, antiphospholipid antibodies and femur head necrosis in patients with SLE: a directed acyclic graph-based multicentre study
Sheng-Bao Chen, Qianying Cai, Yanjun Xu, Qiong Fu +11 more
2021Therapeutic Advances in Musculoskeletal Disease15 citations Open access
Semantic Scholar
on Human B Cell Differentiation 3 DModulatory Effects of 1,25-Dihydroxyvitamin
Sheng Chen, G. Sims, Xiao-Xiang Chen, Yue-Ying Gu +2 more
200714 citations
Semantic Scholar
Evaluation of interferon‐gamma release assay (T‐SPOT.TB™) for diagnosis of tuberculosis infection in rheumatic disease patients
B. Jiang, Hui-Hua Ding, Li Zhou, Xiao-Xiang Chen +2 more
2016International Journal of Rheumatic Diseases13 citations Open access
Semantic Scholar
A randomized, controlled trial of efficacy and safety of Anbainuo, a bio-similar etanercept, for moderate to severe rheumatoid arthritis inadequately responding to methotrexate
Xiao-Xiang Chen, Zhan-Guo Li, Hua-xiang Wu, Dong-Bao Zhao +10 more
2016Clinical Rheumatology12 citations
Semantic Scholar
Dynamic changes in serum IL-6, IL-8, and IL-10 are associated with the outcome of patients with severe COVID-19 in ICU
Jia Li, L. Rong, R. Cui, Jiaqi Feng +4 more
20209 citations Open access
Semantic Scholar
Improved synergetic therapy efficiency of cryoablation and nanoparticles for MCF-7 breast cancer.
Ping Ye, Hai-Tao Yin, Xuelian Gu, Yuan-Yuan Ye +5 more
2018Nanomedicine7 citations
Semantic Scholar
Recent progress in nanomaterials for the detection of rheumatoid arthritis-related biomarkers: A clinical perspective
Nan Sheng, Rui Song, Yan Ye, Anqi Wu +3 more
Nano Biomedicine and Engineering7 citations Open access
Semantic Scholar
Synovial CXCL3+FOSL2+ Macrophages Mediate Inflammation via FOSL2/AP-1 in Rheumatoid Arthritis: A Single-Cell Transcriptome Analysis
Yi-Wei Wu, Jinming Yang, Meng-Ke Chen, Xiao-Xiang Chen +1 more
2025International Journal of Molecular Sciences6 citations
Semantic Scholar
Enhancing the treatment potential of IL-17 antagonism in lupus nephritis: finding the right partner
Ying-Ying Gao, Guo-Yuan Peng, Xin Liu, Xiaochen Ren +2 more
2025Frontiers in Immunology5 citations Open access
Semantic Scholar
Efficacy of Combination Therapy With Pirfenidone and Low-Dose Cyclophosphamide for Refractory Interstitial Lung Disease Associated With Connective Tissue Disease: A Case-Series of Seven Patients.
Li-Chong Shen, Q. Yan, Xiao-Xiang Chen
2019Archives of Rheumatology5 citations Open access
Semantic Scholar
[Variations within OLF1/EBF-associated zinc finger protein gene confer susceptibility to lupus nephritis in Chinese population].
Dong Liang, Xiu-Qin Huang, N. Shen, Han Mao +9 more
2005Zhonghua yi xue za zhi5 citations
Semantic Scholar
IL-6R blockade combined with immunosuppressants alleviates adult-onset Still’s disease through immune remodeling: a mass cytometry study
Ru-Ru Guo, Ting Zhang, Yi-Xuan Li, Xue-Song Liu +5 more
2025Journal of Translational Medicine4 citations Open access
Semantic Scholar
Iguratimod attenuated fibrosis in systemic sclerosis via targeting early growth response 1 expression
Li-Chong Shen, Hanlin Yin, Li Sun, Zhi-Liang Zhang +10 more
2023Arthritis Research & Therapy4 citations Open access
Semantic Scholar
Engineered CRISPRa System for Precise and Multiplex Gene Regulation Using a Hybrid dCas12a Variant and Hairpin-Spacer crRNAs.
Yuqing Ke, Shuang Zhang, Ying-Ying Gao, Xiao-Xiang Chen +4 more
2024Analytical Chemistry3 citations
Semantic Scholar
Zr-NMOF tagged with heterobifunctionalized aptamers for highly sensitive, multiplexed and rapid imaging mass cytometry.
Kaiwen Bao, Xiao-Xiang Chen, Rui Chen, Ying-Ying Gao +8 more
2024Nanoscale3 citations
Semantic Scholar
Elevated Serum D-Dimer May Reflect the Presence of Gut Inflammation in Spondyloarthritis
Jiaqi Feng, Jia Li, Yixuan Li, Yuebo Jin +2 more
2022Frontiers in Medicine3 citations Open access
Semantic Scholar
SAT0001 L-ARGININE SUPPLEMENTATION AMELIORATES BONE EROSION IN RHEUMATOID ARTHRITIS THROUGH INHIBITION OF RANKL/RANK/TRAF6 PATHWAY AND REPROGRAMMING OSTEOCLAST METABOLISM
S. Cao, Xiao-Xiang Chen, G. Schett, A. Bozec
2020Annals of the Rheumatic Diseases3 citations Open access
Semantic Scholar

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Yue-Ying Gu×8
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Xin-Yu Meng — researcher profile on SciRah

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Shun-le Chen×6

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Yixuan Li — researcher profile on SciRah

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Xue-Song Liu×5

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