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Prem Kumar · SciRah

Researcher profile · Semantic Scholar

Prem Kumar

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Prem Kumar — researcher profile on SciRah

h-index: 21
Works: 82
Citations: 1,902

Most-cited papers

Peripheral Chemoreceptors: Function and Plasticity of the Carotid Body
Prem Kumar, N. Prabhakar
2012Comprehensive Physiology509 citations Open access
Semantic Scholar
AMP-ACTIVATED PROTEIN KINASE MEDIATES CAROTID BODY EXCITATION BY HYPOXIA
Christopher N. Wyatt, K. J. Mustard, Selina A. Pearson, M. Dallas +5 more
2006Journal of Biological Chemistry164 citations Open access
Semantic Scholar
Absence of Ventilatory Responses to Alternating Breaths of Mild Hypoxia and Air in Infants Who Have Had Bronchopulmonary Dysplasia: Implications for the Risk of Sudden Infant Death
N. Calder, B. A. Williams, J. Smyth, A. Boon +2 more
1994Pediatric Research98 citations
Semantic Scholar
Indirect sensing of insulin‐induced hypoglycaemia by the carotid body in the rat
I. Bin-Jaliah, P. Maskell, Prem Kumar
2004Journal of Physiology95 citations Open access
Semantic Scholar
Adequate stimuli of the carotid body: more than an oxygen sensor?
Prem Kumar, I. Bin-Jaliah
2007Respiratory Physiology & Neurobiology88 citations
Semantic Scholar
Sensing hypoxia in the carotid body: from stimulus to response.
Prem Kumar
2007Essays in Biochemistry58 citations
Semantic Scholar
Postnatal development of the pattern of respiratory and cardiovascular response to systemic hypoxia in the piglet: the roles of adenosine.
B. Elnazir, Janice M. Marshall, Prem Kumar
1996Journal of Physiology55 citations Open access
Semantic Scholar
Systemic effects resulting from carotid body stimulation-invited article.
Prem Kumar
2009Advances in Experimental Medicine and Biology54 citations
Semantic Scholar
AMP-activated Protein Kinase Deficiency Blocks the Hypoxic Ventilatory Response and Thus Precipitates Hypoventilation and Apnea.
A. Mahmoud, S. Lewis, L. Juričić, U. Udoh +12 more
2016American Journal of Respiratory and Critical Care Medicine46 citations Open access
Semantic Scholar
Development of respiratory chemoreflexes in response to alternations of fractional inspired oxygen in the newborn infant.
B. A. Williams, J. Smyth, A. W. Boon, M. Hanson +2 more
1991Journal of Physiology46 citations Open access
Semantic Scholar
Ion Channel Regulation by AMPK
A. Evans, D. G. Hardie, C. Peers, C. Wyatt +9 more
2009Annals of the New York Academy of Sciences43 citations
Semantic Scholar
Long‐term facilitation of ventilation following acute continuous hypoxia in awake humans during sustained hypercapnia
H. Griffin, K. Pugh, Prem Kumar, G. Balanos
2012Journal of Physiology41 citations Open access
Semantic Scholar
The Respiratory Response of Healthy Term Infants to Breath-by-Breath Alternations in Inspired Oxygen at Two Postnatal Ages
N. Calder, B. A. Williams, Prem Kumar, M. Hanson
1994Pediatric Research40 citations
Semantic Scholar
University of Birmingham Adrenaline release evokes hyperpnoea and an increase in ventilatory CO2 sensitivity during hypoglycaemia: a role for the carotid body
Emma Thompson, C. Ray, Andrew P. Holmes, Richard L. Pye +3 more
201637 citations
Semantic Scholar
Carbon dioxide sensitivity during hypoglycaemia‐induced, elevated metabolism in the anaesthetized rat
I. Bin-Jaliah, P. Maskell, Prem Kumar
2005Journal of Physiology36 citations
Semantic Scholar
A Possible Dual Site of Action for Carbon Monoxide‐Mediated Chemoexcitation in the Rat Carotid Body
C. Barbé, F. Al-Hashem, A. F. Conway, E. Dubuis +2 more
2002Journal of Physiology34 citations Open access
Semantic Scholar
AMP-activated protein kinase couples mitochondrial inhibition by hypoxia to cell-specific Ca2+ signalling mechanisms in oxygen-sensing cells.
A. Evans, D. G. Hardie, A. Galione, C. Peers +2 more
2006Novartis Foundation symposium27 citations
Semantic Scholar
Glycogen metabolism protects against metabolic insult to preserve carotid body function during glucose deprivation
Andrew P. Holmes, Philip J. Turner, P. Carter, W. Leadbeater +4 more
2014Journal of Physiology25 citations Open access
Semantic Scholar
A respiratory response to the activation of the muscle metaboreflex during concurrent hypercapnia in man
Christos K. Lykidis, Prem Kumar, L. Vianna, M. White +1 more
2010Experimental Physiology25 citations Open access
Semantic Scholar
Moderate inhibition of mitochondrial function augments carotid body hypoxic sensitivity
Andrew P. Holmes, Philip J. Turner, K. Buckler, Prem Kumar
2015Pflügers Archiv: European Journal of Physiology21 citations Open access
Semantic Scholar
Interactions between K+ and beta 2‐adrenoreceptors in determining muscle vasodilatation induced in the rat by systemic hypoxia
R. Mian, Janice M. Marshall, Prem Kumar
1990Experimental Physiology21 citations
Semantic Scholar
Is Carotid Body Physiological O2 Sensitivity Determined by a Unique Mitochondrial Phenotype?
Andrew P. Holmes, C. Ray, A. Coney, Prem Kumar
2018Frontiers in Physiology19 citations Open access
Semantic Scholar
Bicarbonate-sensitive soluble and transmembrane adenylyl cyclases in peripheral chemoreceptors
A. R. Nunes, Andrew P. Holmes, Vedangi Sample, Prem Kumar +4 more
2013Respiratory Physiology & Neurobiology19 citations Open access
Semantic Scholar
Sensing hypoxia: carotid body mechanisms and reflexes in health and disease.
Prem Kumar, N. Prabhakar
2007Respiratory Physiology & Neurobiology19 citations
Semantic Scholar
G-Protein-Coupled Receptor (GPCR) Signaling in the Carotid Body: Roles in Hypoxia and Cardiovascular and Respiratory Disease
Hayyaf S Aldossary, A. Alzahrani, Demitris Nathanael, Eyas A. Alhuthail +5 more
2020International Journal of Molecular Sciences18 citations Open access
Semantic Scholar
Ecto‐5′‐nucleotidase (CD73) regulates peripheral chemoreceptor activity and cardiorespiratory responses to hypoxia
Andrew P. Holmes, C. Ray, Selina A. Pearson, A. Coney +1 more
2017Journal of Physiology18 citations Open access
Semantic Scholar
How sweet it is: sensing low glucose in the carotid body
Prem Kumar
2007Journal of Physiology18 citations Open access
Semantic Scholar
Calcium oscillations induced by ATP in human umbilical cord smooth muscle cells
F. Meng, W. To, J. Kirkman-Brown, Prem Kumar +1 more
2006Journal of Cellular Physiology18 citations
Semantic Scholar
Mitochondrial Succinate Metabolism and Reactive Oxygen Species Are Important but Not Essential for Eliciting Carotid Body and Ventilatory Responses to Hypoxia in the Rat
Agnieszka Swiderska, A. Coney, A. Alzahrani, Hayyaf S Aldossary +4 more
2021Antioxidants16 citations Open access
Semantic Scholar
Ecto-5'-Nucleotidase, Adenosine and Transmembrane Adenylyl Cyclase Signalling Regulate Basal Carotid Body Chemoafferent Outflow and Establish the Sensitivity to Hypercapnia.
Andrew P. Holmes, A. R. Nunes, M. J. Cann, Prem Kumar
2015Advances in Experimental Medicine and Biology16 citations Open access
Semantic Scholar
The drive to breathe and sudden infant death syndrome
M. Hanson, N. Calder, Takanori Watanabe, Prem Kumar
1993Acta paediatrica16 citations
Semantic Scholar
β-Adrenoceptor blockade prevents carotid body hyperactivity and elevated vascular sympathetic nerve density induced by chronic intermittent hypoxia
A. Alzahrani, Lily L. Cao, Hayyaf S Aldossary, Demitris Nathanael +6 more
2020Pflügers Archiv: European Journal of Physiology15 citations Open access
Semantic Scholar
Ion channel regulation by the Lkb1‐AMPK signalling pathway: the key to carotid body activation by hypoxia and metabolic homeostasis at the whole body level
A. M. Evans, C. Peers, C. Wyatt, Prem Kumar +1 more
2012Advances in Experimental Medicine and Biology14 citations Open access
Semantic Scholar
A student practical to conceptualize the importance of Poiseuille's law and flow control in the cardiovascular system.
Andrew P. Holmes, C. Ray, Prem Kumar, A. Coney
2020Advances in Physiology Education13 citations Open access
Semantic Scholar
The impact of acute and chronic catecholamines on respiratory responses to hypoxic stress in the rat
D. Hauton, Andrew P. Holmes, O. Ziff, Prem Kumar
2013Pflügers Archiv: European Journal of Physiology13 citations
Semantic Scholar
Adrenaline activation of the carotid body: Key to CO2 and pH homeostasis in hypoglycaemia and potential pathological implications in cardiovascular disease.
Andrew P. Holmes, C. Ray, E. Thompson, Z. Alshehri +2 more
2019Respiratory Physiology & Neurobiology10 citations Open access
Semantic Scholar
Are Multiple Mitochondrial Related Signalling Pathways Involved in Carotid Body Oxygen Sensing?
Andrew P. Holmes, Agnieszka Swiderska, Demitris Nathanael, Hayyaf S Aldossary +3 more
2022Frontiers in Physiology9 citations Open access
Semantic Scholar
The respiratory responses to the combined activation of the muscle metaboreflex and the ventilatory chemoreflex.
Christos K. Lykidis, Prem Kumar, G. Balanos
2009Advances in Experimental Medicine and Biology9 citations
Semantic Scholar
Key roles for AMP-activated protein kinase in the function of the carotid body?
Christopher N. Wyatt, Selina A. Pearson, Prem Kumar, C. Peers +2 more
2008Advances in Experimental Medicine and Biology9 citations
Semantic Scholar
Adrenaline increases carotid body CO2 sensitivity: an in vivo study.
P. Maskell, C. Rusius, K. Whitehead, Prem Kumar
2006Advances in Experimental Medicine and Biology9 citations
Semantic Scholar
AMP‐activated protein kinase: function and dysfunction in health and disease
Prem Kumar, C. Peers
2006Journal of Physiology7 citations Open access
Semantic Scholar
Mild Chronic Intermittent Hypoxia in Wistar Rats Evokes Significant Cardiovascular Pathophysiology but No Overt Changes in Carotid Body-Mediated Respiratory Responses.
C. Ray, B. Dow, Prem Kumar, A. Coney
2015Advances in Experimental Medicine and Biology6 citations
Semantic Scholar
LKB1 is the gatekeeper of carotid body chemosensing and the hypoxic ventilatory response
S. MacMillan, Andrew P. Holmes, M. Dallas, A. Mahmoud +5 more
2022Communications Biology5 citations Open access
Semantic Scholar
Comments on point: counterpoint: high altitude is/is not for the birds!
Darren P. Casey, C. Imray, M. Wilson, A. Flouris +13 more
2011Journal of applied physiology5 citations
Semantic Scholar
Elevation of Metabolic Rate by Pyrogen Administration Does Not Affect the Gain of Respiratory Peripheral Chemoreflexes in Unanesthetized Kittens
Takanori Watanabe, Prem Kumar, M. Hanson
1998Pediatric Research5 citations Open access
Semantic Scholar
The interaction between low glucose and hypoxia in the in vitro, rat carotid body.
Andrew P. Holmes, D. Hauton, Prem Kumar
2012Advances in Experimental Medicine and Biology4 citations
Semantic Scholar
A role for TRP channels in carotid body chemotransduction?
Prem Kumar, Selina A. Pearson, Yuchun Gu
20064 citations
Semantic Scholar
Analyzing Angiotensin II Receptor Type 1 Clustering in PC12 Cells in Response to Hypoxia Using Direct Stochastic Optical Reconstruction Microscopy (dSTORM).
Hayyaf S Aldossary, D. Nieves, Deirdre M. Kavanagh, Dylan Owen +4 more
2023Advances in Experimental Medicine and Biology3 citations
Semantic Scholar
The carotid body in cardiovascular disease: more chicken and egg than horse and cart?
Prem Kumar
2012Journal of Physiology3 citations Open access
Semantic Scholar
Peripheral Chemoreceptors in Mammals: Structure, Function and Transduction
Prem Kumar
20093 citations
Semantic Scholar

Frequent co-authors

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Andrew P. Holmes×16
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Andrew P. Holmes — researcher profile on SciRah
C. Ray×12
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C. Ray — researcher profile on SciRah
A. Coney×11
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A. Coney — researcher profile on SciRah
C. Peers×7
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C. Peers — researcher profile on SciRah

Hayyaf S Aldossary

×5

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Hayyaf S Aldossary — researcher profile on SciRah

Selina A. Pearson×4

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Selina A. Pearson — researcher profile on SciRah

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M. Hanson — researcher profile on SciRah

D. G. Hardie×4

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D. G. Hardie — researcher profile on SciRah

Christopher N. Wyatt×3

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Christopher N. Wyatt — researcher profile on SciRah

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M. Dallas — researcher profile on SciRah

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A. Evans — researcher profile on SciRah

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N. Calder — researcher profile on SciRah