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K. E. Lundin · SciRah

Researcher profile · Semantic Scholar

K. E. Lundin

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K. E. Lundin — researcher profile on SciRah

h-index: 20
Works: 52
Citations: 1,040

Most-cited papers

Oligonucleotide Therapies: The Past and the Present
K. E. Lundin, O. Gissberg, C. Edvard Smith
2015Human Gene Therapy194 citations Open access
Semantic Scholar
Biological activity and biotechnological aspects of peptide nucleic acid.
K. E. Lundin, L. Good, R. Strömberg, A. Gräslund +1 more
2006Advances in Genetics103 citations
Semantic Scholar
Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model.
Burcu Bestas, Pedro M. D. Moreno, K. Blomberg, D. K. Mohammad +17 more
2014Journal of Clinical Investigation43 citations Open access
Semantic Scholar
LNA effects on DNA binding and conformation: from single strand to duplex and triplex structures
Y. V. Pabón-Martínez, You Xu, A. Villa, K. E. Lundin +8 more
2017Scientific Reports36 citations Open access
Semantic Scholar
Formulation and delivery of splice-correction antisense oligonucleotides by amino acid modified polyethylenimine.
E. Zaghloul, Joana R. Viola, G. Zuber, C. Edvard Smith +1 more
2010Molecular Pharmaceutics36 citations
Semantic Scholar
A synthetic snRNA m3G-CAP enhances nuclear delivery of exogenous proteins and nucleic acids
Pedro M. D. Moreno, Malgorzata Wenska, K. E. Lundin, O. Wrange +2 more
2009Nucleic Acids Research35 citations Open access
Semantic Scholar
Gene Transfer to Mouse Heart and Skeletal Muscles Using a Minicircle Expressing Human Vascular Endothelial Growth Factor
Sofia Stenler, Agneta B. Andersson, Oscar E. Simonson, K. E. Lundin +5 more
2009Journal of Cardiovascular Pharmacology34 citations
Semantic Scholar
Susceptibility to infections, without concomitant hyper-IgE, reported in 1976, is caused by hypomorphic mutation in the phosphoglucomutase 3 (PGM3) gene
K. E. Lundin, A. Hamasy, P. H. Backe, L. Moens +10 more
2015Clinical Immunology33 citations Open access
Semantic Scholar
Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA
Pedro M. D. Moreno, S. Geny, Y. V. Pabon, Helen Bergquist +11 more
2013Nucleic Acids Research32 citations Open access
Semantic Scholar
Zorro locked nucleic acid induces sequence‐specific gene silencing
R. Ge, Juhana E. Heinonen, Mathias G. Svahn, Abdalla J. Mohamed +2 more
2007The FASEB Journal30 citations
Semantic Scholar
Next-generation bis-locked nucleic acids with stacking linker and 2′-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes
S. Geny, Pedro M. D. Moreno, T. Krzywkowski, O. Gissberg +15 more
2016Nucleic Acids Research29 citations Open access
Semantic Scholar
Micro-minicircle Gene Therapy: Implications of Size on Fermentation, Complexation, Shearing Resistance, and Expression
Sofia Stenler, O. Wiklander, Maria Badal-Tejedor, Janne J. Turunen +8 more
2014Molecular Therapy: Nucleic Acids29 citations Open access
Semantic Scholar
Optimizing anti-gene oligonucleotide ‘Zorro-LNA’ for improved strand invasion into duplex DNA
E. Zaghloul, A. Madsen, Pedro M. D. Moreno, I. Oprea +7 more
2010Nucleic Acids Research28 citations Open access
Semantic Scholar
Cooperative strand invasion of supercoiled plasmid DNA by mixed linear PNA and PNA-peptide chimeras.
K. E. Lundin, R. Ge, M. Svahn, E. Törnquist +3 more
2004Biomolecular Engineering24 citations Open access
Semantic Scholar
Increased stability and specificity through combined hybridization of peptide nucleic acid (PNA) and locked nucleic acid (LNA) to supercoiled plasmids for PNA-anchored "Bioplex" formation.
K. E. Lundin, Maroof Hasan, Pedro M. D. Moreno, E. Törnquist +4 more
2005Biomolecular Engineering23 citations
Semantic Scholar
Nanotechnology approaches for gene transfer
K. E. Lundin, Oscar E. Simonson, Pedro M. D. Moreno, E. Zaghloul +3 more
2009Genetica22 citations
Semantic Scholar
Adding functional entities to plasmids
M. G. Svahn, K. E. Lundin, R. Ge, E. Törnquist +5 more
2004Journal of Gene Medicine22 citations
Semantic Scholar
RNA therapeutics inactivate PCSK9 by inducing a unique intracellular retention form.
Cristina S. J. Rocha, O. Wiklander, L. Larsson, Pedro M. D. Moreno +3 more
2015Journal of Molecular and Cellular Cardiology21 citations Open access
Semantic Scholar
Novel peptide‐dendrimer/lipid/oligonucleotide ternary complexes for efficient cellular uptake and improved splice‐switching activity
O. Saher, Cristina S. J. Rocha, E. Zaghloul, O. Wiklander +11 more
2018European journal of pharmaceutics and biopharmaceutics20 citations Open access
Semantic Scholar
CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression
E. Zaghloul, O. Gissberg, Pedro M. D. Moreno, Lee Siggens +7 more
2017Nucleic Acids Research20 citations Open access
Semantic Scholar
Fatty acid–spermine conjugates as DNA carriers for nonviral in vivo gene delivery
Joana R. Viola, H. Leijonmarck, Oscar E. Simonson, I. Oprea +6 more
2009Gene Therapy20 citations Open access
Semantic Scholar
Lipophilic Peptide Dendrimers for Delivery of Splice-Switching Oligonucleotides
Haneen Daralnakhla, O. Saher, Susanna Zamolo, Safa Bazaz +8 more
2021Pharmaceutics18 citations Open access
Semantic Scholar
Sugar and Polymer Excipients Enhance Uptake and Splice-Switching Activity of Peptide-Dendrimer/Lipid/Oligonucleotide Formulations
O. Saher, Taavi Lehto, O. Gissberg, Dhanu Gupta +6 more
2019Pharmaceutics18 citations Open access
Semantic Scholar
Four Novel Splice-Switch Reporter Cell Lines: Distinct Impact of Oligonucleotide Chemistry and Delivery Vector on Biological Activity
Cristina S. J. Rocha, K. E. Lundin, M. Behlke, R. Zain +2 more
2016Nucleic Acid Therapeutics16 citations
Semantic Scholar
Bioplex technology: novel synthetic gene delivery pharmaceutical based on peptides anchored to nucleic acids.
Oscar E. Simonson, M. Svahn, E. Törnquist, K. E. Lundin +1 more
2005Current pharmaceutical design16 citations
Semantic Scholar
Role of Pseudoisocytidine Tautomerization in Triplex-Forming Oligonucleotides: In Silico and in Vitro Studies
Y. Hartono, Y. Vladimir Pabon-Martinez, Arzu Uyar, J. Wengel +5 more
2017ACS Omega14 citations Open access
Semantic Scholar
Chemical Development of Therapeutic Oligonucleotides.
K. E. Lundin, O. Gissberg, C. Edvard Smith, R. Zain
2019Methods in molecular biology12 citations
Semantic Scholar
Oligonucleotide–Palladacycle Conjugates as Splice-Correcting Agents
Madhuri Hande, O. Saher, K. E. Lundin, C. Edvard Smith +2 more
2019Molecules12 citations Open access
Semantic Scholar
The ability of locked nucleic acid oligonucleotides to pre-structure the double helix: A molecular simulation and binding study
You Xu, O. Gissberg, Y. Vladimir Pabon-Martinez, J. Wengel +5 more
2019PLoS ONE11 citations Open access
Semantic Scholar
Eleven percent intact PGM3 in a severely immunodeficient patient with a novel splice-site mutation, a case report
K. E. Lundin, Qing Wang, A. Hamasy, P. Marits +6 more
2018BMC Pediatrics11 citations Open access
Semantic Scholar
Sequence‐specific inhibition of RNA polymerase III‐dependent transcription using Zorro locked nucleic acid (LNA)
R. Ge, Mathias G. Svahn, Oscar E. Simonson, Abdalla J. Mohamed +2 more
2008Journal of Gene Medicine11 citations
Semantic Scholar
Self-Assembling Supramolecular Complexes by Single-Stranded Extension from Plasmid DNA
M. Svahn, Maroof Hasan, Valeria Sigot, J. J. Valle-Delgado +3 more
2007Oligonucleotides10 citations
Semantic Scholar
Delivery, Effect on Cell Viability, and Plasticity of Modified Aptamer Constructs
O. Gissberg, E. Zaghloul, K. E. Lundin, C. Nguyen +4 more
2016Nucleic Acid Therapeutics9 citations
Semantic Scholar
Micro-minicircle Gene Therapy: Implications of Size on Fermentation, Complexation, Shearing Resistance, and Expression.
Sofia Stenler, O. Wiklander, Maria Badal-Tejedor, Janne J. Turunen +8 more
2014Molecular Therapy: Nucleic Acids7 citations Open access
Semantic Scholar
Anti-gene oligonucleotide clamps invade dsDNA and downregulate huntingtin expression
Tea Umek, K. E. Lundin, M. Mowoe, Yitong Hao +8 more
2024Molecular Therapy: Nucleic Acids6 citations Open access
Semantic Scholar
Chemical Modifications and Design Influence the Potency of Huntingtin Anti-Gene Oligonucleotides
O. Saher, E. Zaghloul, Tea Umek, Daniel W. Hagey +8 more
2023Nucleic Acid Therapeutics6 citations Open access
Semantic Scholar
Oligonucleotides Targeting DNA Repeats Downregulate Huntingtin Gene Expression in Huntington's Patient-Derived Neural Model System
Tea Umek, T. Olsson, O. Gissberg, O. Saher +8 more
2021Nucleic Acid Therapeutics6 citations Open access
Semantic Scholar
LNA effects on DNA binding and conformation: from single strand to duplex and triplex structures
Y. V. Pabón-Martínez, You Xu, Alessandra Villa, K. E. Lundin +8 more
2017Scientific Reports6 citations Open access
Semantic Scholar
Oligonucleotide Binding to Non-B-DNA in MYC
Tea Umek, K. Sollander, Helen Bergquist, J. Wengel +3 more
2019Molecules5 citations Open access
Semantic Scholar
2′-O-(N-(Aminoethyl)carbamoyl)methyl Modification Allows for Lower Phosphorothioate Content in Splice-Switching Oligonucleotides with Retained Activity
D. Honcharenko, Cristina S. J. Rocha, K. E. Lundin, Jyotirmoy Maity +8 more
2022Nucleic Acid Therapeutics4 citations Open access
Semantic Scholar
Repeatable, Inducible Micro-RNA-Based Technology Tightly Controls Liver Transgene Expression
I. Oprea, Joana R. Viola, Pedro M. D. Moreno, Oscar E. Simonson +6 more
2014Molecular Therapy: Nucleic Acids3 citations Open access
Semantic Scholar
Fast and efficient synthesis of Zorro-LNA type 3'-5'-5'-3' oligonucleotide conjugates via parallel in situ stepwise conjugation.
O. Gissberg, M. Jezowska, E. Zaghloul, N. I. Bungsu +4 more
2016Organic and biomolecular chemistry2 citations
Semantic Scholar
Cell-penetrating peptide-conjugated, splice-switching oligonucleotides mitigate the phenotype in BTK/Tec double deficient X-linked agammaglobulinemia model
Burcu Bestas, H. Y. Estupiñán, Qing Wang, Shabnam Kharazi +18 more
2025RSC Chemical Biology1 citations Open access
Semantic Scholar
Temperature-Assisted Cyclic Hybridization (TACH): An Improved Method for Supercoiled DNA Hybridization
I. Oprea, Oscar E. Simonson, Pedro M. D. Moreno, Joana R. Viola +2 more
2010Molecular Biotechnology1 citations
Semantic Scholar
Building biologically active nucleic acid nanocomplexes.
C. Edvard Smith, K. E. Lundin, Oscar E. Simonson, Pedro M. D. Moreno +3 more
2008Nucleic Acids Symposium Series1 citations Open access
Semantic Scholar
Syddansk Universitet Role of Pseudoisocytidine Tautomerization in Triplex-Forming Oligonucleotides In Silico and in Vitro Studies
Y. Hartono, Y. V. Pabón-Martínez, Arzu Uyar, J. Wengel +5 more
20170 citations
Semantic Scholar
University of Southern Denmark Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes Geny,
S. Geny, Pedro M. D. Moreno, T. Krzywkowski, O. Gissberg +18 more
20160 citations
Semantic Scholar
MICRO-MINICIRCLE VECTORS FOR SPLICE-SWITCHING IN MOUSE MODEL OF DUCHENNE MUSCULAR DYSTROPHY
Sofia Stenler, S. el Andaloussi, S. Hammond, A. Goyenvalle +5 more
20150 citations
Semantic Scholar
695. Splice-Correction of X-Linked Agammaglobulinemia in a Human BAC-Transgenic Mouse Model Using Oligonucleotides
Burcu Bestas, Pedro M. D. Moreno, E. Blomberg, D. K. Mohammad +5 more
20150 citations Open access
Semantic Scholar
Personalized therapy for X-linked agammaglobulinemia (XLA) by oligonucleotide-induced splice-correction
Burcu Bestas, Moreno Pmd., Blomberg Kem., D. K. Mohammad +14 more
20140 citations
Semantic Scholar

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