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Dun-Rui Wang · SciRah

Researcher profile · Semantic Scholar

Dun-Rui Wang

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Dun-Rui Wang — researcher profile on SciRah

h-index: 19
Works: 67
Citations: 976

Most-cited papers

The nucleic acid binding activity of nucleolar protein B23.1 resides in its carboxyl-terminal end.
Dun-Rui Wang, A. Baumann, A. Szebeni, M. Olson
1994Journal of Biological Chemistry114 citations Open access
Semantic Scholar
CD70 as a target for chimeric antigen receptor T cells in head and neck squamous cell carcinoma
Y. Park, Lin-Chun Jin, Katie B Bennett, Dun-Rui Wang +5 more
2018Oral Oncology64 citations Open access
Semantic Scholar
The Expression of Glyceraldehyde-3-Phosphate Dehydrogenase Associated Cell Cycle (GACC) Genes Correlates with Cancer Stage and Poor Survival in Patients with Solid Tumors
Dun-Rui Wang, Daniel R. Moothart, D. Lowy, X. Qian
2013PLoS ONE60 citations Open access
Semantic Scholar
cProSite: A web based interactive platform for online proteomics, phosphoproteomics, and genomics data analysis
Dun-Rui Wang, X. Qian, Y. Du, Beatriz Sánchez-Solana +12 more
2023bioRxiv59 citations Open access
Semantic Scholar
CDK5 is a major regulator of the tumor suppressor DLC1
B. Tripathi, X. Qian, Philipp Mertins, Dun-Rui Wang +3 more
2014Journal of Cell Biology58 citations Open access
Semantic Scholar
Expression of the receptor for hyaluronic acid mediated motility (RHAMM) is associated with poor prognosis and metastasis in non-small cell lung carcinoma
Dun-Rui Wang, N. Narula, S. Azzopardi, Roger S. Smith +6 more
2016OncoTarget47 citations Open access
Semantic Scholar
Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression
Soyoung Choi, Dun-Rui Wang, Xiang Chen, Laura H. Tang +12 more
2019Molecular Cancer46 citations Open access
Semantic Scholar
DLC1 is the principal biologically-relevant down-regulated DLC family member in several cancers
Dun-Rui Wang, X. Qian, Megha Rajaram, M. Durkin +1 more
2016OncoTarget41 citations Open access
Semantic Scholar
Defining a novel 75-kDa phosphoprotein associated with SS-A/Ro and identification of distinct human autoantibodies.
Dun-Rui Wang, Jill P. Buyon, Wei-Guo Zhu, Edward K. L. Chan
1999Journal of Clinical Investigation41 citations Open access
Semantic Scholar
Tumor-infiltrating myeloid cells activate Dll4/Notch/TGF-β signaling to drive malignant progression
Hidetaka Ohnuki, Kan Jiang, Dun-Rui Wang, O. Salvucci +4 more
2014Cancer Research40 citations Open access
Semantic Scholar
Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1
B. Tripathi, T. Grant, X. Qian, Ming Zhou +7 more
2017Journal of Cell Biology37 citations Open access
Semantic Scholar
MicroRNA-375 as a biomarker for malignant transformation in oral lesions.
Amani M. Harrandah, S. Fitzpatrick, M. H. Smith, Dun-Rui Wang +2 more
2016Oral surgery, oral medicine, oral pathology and oral radiology35 citations
Semantic Scholar
17-β-Estradiol Increases Expression of 52-kDa and 60-kDa SS-A/Ro Autoantigens in Human Keratinocytes and Breast Cancer Cell Line MCF-7
Dun-Rui Wang, E. K. Chan
199633 citations Open access
Semantic Scholar
Studies characterizing 60 kda autoantibodies in subjects with schizophrenia.
Xiao-Fen Wang, Dun-Rui Wang, Weiguo Zhu, K. Delrahim +2 more
2003Biological Psychiatry31 citations
Semantic Scholar
Leucine zipper domain of 52 kDa SS-A/Ro promotes protein dimer formation and inhibits in vitro transcription activity.
Dun-Rui Wang, J. Buyon, Zheng Yang, F. Di Donato +2 more
2001Biochimica et Biophysica Acta28 citations
Semantic Scholar
High levels of truncated RHAMM cooperate with dysfunctional p53 to accelerate the progression of pancreatic cancer
A. Lin, Jennifer Feng, Xiang Chen, Dun-Rui Wang +7 more
2021bioRxiv23 citations Open access
Semantic Scholar
Molecular and Cellular Pathobiology Inactivation of the Dlc 1 Gene Cooperates with Downregulation of p 15 INK 4 b and p 16 Ink 4 a , Leading to Neoplastic Transformation and Poor Prognosis in Human Cancer
X. Qian, M. Durkin, Dun-Rui Wang, B. Tripathi +5 more
201223 citations
Semantic Scholar
Cancer-associated point mutations in the DLC1 tumor suppressor and other Rho-GAPs occur frequently and are associated with decreased function
Dun-Rui Wang, X. Qian, Beatriz Sánchez-Solana, B. Tripathi +2 more
2020Cancer Research21 citations Open access
Semantic Scholar
Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein
B. Tripathi, Meghan F Anderman, D. Bhargava, Luciarita Boccuzzi +9 more
2021Nature Communications19 citations Open access
Semantic Scholar
Targeting the SHP2 phosphatase promotes vascular damage and inhibition of tumor growth
Yuyi Wang, O. Salvucci, Hidetaka Ohnuki, Andy D. Tran +8 more
2020bioRxiv19 citations Open access
Semantic Scholar
SRC and ERK cooperatively phosphorylate DLC1 and attenuate its Rho-GAP and tumor suppressor functions
B. Tripathi, Meghan F Anderman, X. Qian, Ming Zhou +3 more
2019Journal of Cell Biology16 citations Open access
Semantic Scholar
Identification of Eph receptor signaling as a regulator of autophagy and a therapeutic target in colorectal carcinoma
M. Diprima, Dun-Rui Wang, Alix Tröster, D. Maric +7 more
2019Molecular Oncology16 citations Open access
Semantic Scholar
DLC1 deficiency and YAP signaling drive endothelial cell contact inhibition of growth and tumorigenesis
Lisa Ritchey, Taekyu Ha, A. Otsuka, K. Kabashima +4 more
2019Oncogene15 citations Open access
Semantic Scholar
Expression of the Receptor for Hyaluronic Acid Mediated Motility (RHAMM) in Endometrial Cancer is Associated with Adverse Histologic Parameters and Tumor Progression
Nina Schatz-Siemers, Yao-Tseng Chen, Zheng-Ming Chen, Dun-Rui Wang +2 more
2019Applied immunohistochemistry & molecular morphology (Print)14 citations Open access
Semantic Scholar
Effects of DLC1 Deficiency on Endothelial Cell Contact Growth Inhibition and Angiosarcoma Progression.
D. Sanchez‐Martin, A. Otsuka, K. Kabashima, Taekyu Ha +4 more
2018Journal of the National Cancer Institute14 citations Open access
Semantic Scholar
The pro-oncogenic noncanonical activity of a RAS•GTP:RanGAP1 complex facilitates nuclear protein export
B. Tripathi, N. Hirsh, X. Qian, Marian E. Durkin +11 more
2024Nature Cancer13 citations Open access
Semantic Scholar
The tumor suppressor activity of DLC1 requires the interaction of its START domain with Phosphatidylserine, PLCD1, and Caveolin-1
Beatriz Sánchez-Solana, Dun-Rui Wang, X. Qian, Parthibane Velayoudame +3 more
2021Molecular Cancer13 citations Open access
Semantic Scholar
Cloning and expression of mouse 60 kDa ribonucleoprotein SS-A/Ro
Dun-Rui Wang, J. Buyon, E. L. Chan
2004Molecular Biology Reports13 citations
Semantic Scholar
Abstract 3912: cProSite: A web based interactive platform for on-line proteomics and phosphoproteomics data analysis
Dun-Rui Wang, X. Qian, Y. Du, Beatriz Sánchez-Solana +8 more
2022Cancer Research8 citations
Semantic Scholar
Inactivation of the Dlc1 gene cooperates with down-regulation of p15INK4b and p16Ink4a leading to neoplastic transformation and poor prognosis in human cancer
X. Qian, Marian E. Durkin, Dun-Rui Wang, B. Tripathi +5 more
2012Cancer Research6 citations Open access
Semantic Scholar
Targeting the epigenome and the integrated stress response to normalize colorectal cancer subclonal plasticity and progression
Lili Li, Taekyu Ha, Jing-Xin Feng, M. Diprima +6 more
2026Cell Death and Disease2 citations Open access
Semantic Scholar
Induced clustering of SHP2-depleted tumor cells in vascular islands restores sensitivity to MEK/ERK inhibition
Yuyi Wang, Hidetaka Ohnuki, Andy D. Tran, Dun-Rui Wang +9 more
2025Journal of Clinical Investigation2 citations Open access
Semantic Scholar
Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis
Tian-Tian Zhang, Sha Li, Y. Tan, Xiang Chen +16 more
2024Cancer Letters2 citations Open access
Semantic Scholar
Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis
Tian-Tian Zhang, Sha Li, Y. Tan, J. Na +12 more
2023bioRxiv2 citations Open access
Semantic Scholar
Single-cell lineage tracing identifies hemogenic endothelial cells in the adult mouse bone marrow
Jing-Xin Feng, Mei-Ting Yang, Lili Li, C. Li +7 more
2025bioRxiv1 citations
Semantic Scholar
Abstract 4387: Identification of new drug combinations that cooperatively target KRAS-dependent nuclear protein export to treat mutant KRAS-driven pancreatic adenocarcinoma
B. Tripathi, S. M. Shahin, X. Qian, Marian E. Durkin +4 more
2025Cancer Research1 citations
Semantic Scholar
Bone marrow hemogenic endothelial cells contribute multilineage hematopoietic progenitors in adult mice
Jing-Xin Feng, Meiting Yang, C. Li, F. Livak +3 more
2022bioRxiv1 citations Open access
Semantic Scholar
Abstract 4359: Several cancer types are associated with increased expression and activity of the ECT2 RhoGEF and decreased expression and activity of the DLC1 RhoGAP, leading to increased RhoA activity
Dun-Rui Wang, X. Qian, M. Durkin, A. Papageorge +1 more
2018Molecular and Cellular Biology / Genetics1 citations
Semantic Scholar
Abstract 1574: CDK5 negatively regulates Rho by phosphorylating and activating the Rho-GAP and tumor suppressor functions of DLC1
B. Tripathi, X. Qian, Philipp Mertins, Dun-Rui Wang +3 more
20141 citations
Semantic Scholar
Abstract 4473: Advancing new rational drug combinations to treat mutant KRAS-driven pancreatic adenocarcinoma.
B. Tripathi, S. M. Shahin, E. Van Meter, Marian E. Durkin +5 more
2026Cancer Research0 citations
Semantic Scholar
Single-cell lineage tracing identifies hemogenic endothelial cells in the adult mouse bone marrow
Jing-Xin Feng, Mei-Ting Yang, Lili Li, C. Li +7 more
2026eLife0 citations Open access
Semantic Scholar
Abstract A010: Advancing new rational drug combinations to treat mutant KRAS-driven pancreatic adenocarcinoma
B. Tripathi, S. M. Shahin, E. Van Meter, Marian E. Durkin +5 more
2026Cancer Research0 citations
Semantic Scholar
Abstract 2089: A pro-oncogenic RAS-GTP:RAN-GAP complex facilitates nuclear protein export and has clinical implications
B. Tripathi, N. Hirsh, David Hansen, X. Qian +12 more
2024Cancer Research0 citations
Semantic Scholar
Abstract 1727: Cytoplasmic EZH2 and the DLC1 tumor suppressor are regulated by the CRM1 nuclear export protein and by specific complex formation between mutant KRAS and RAN-GAP
B. Tripathi, N. Hirsh, David Hansen, X. Qian +7 more
2023Cancer Research0 citations
Semantic Scholar
Abstract B023: RHAMMB promotes pancreatic cancer metastasis
Xiang Chen, Tian-Tian Zhang, Seung-Koo Lee, Dun-Rui Wang +4 more
2022Cancer Research0 citations
Semantic Scholar
Abstract 5848: Inhibition of the CRM1 nuclear export protein can treat mutant KRAS tumors through stabilizing the DLC1 tumor suppressor protein
B. Tripathi, N. Hirsh, X. Qian, Dun-Rui Wang +5 more
2022Cancer Research0 citations
Semantic Scholar
Abstract PO-060: N-terminal RHAMM cooperates with dysfunctional p53 to accelerate the progression of pancreatic cancer
A. Lin, Jennifer Feng, Xiang Chen, Dun-Rui Wang +7 more
2021Preclinical Models0 citations
Semantic Scholar
Abstract 2508: Targeting mutantKRAStumors by inhibiting cytoplasmic EZH2, which directly methylates and destabilizes the DLC1 tumor suppressor protein
B. Tripathi, D. Bhargava, X. Qian, Dun-Rui Wang +6 more
2021Molecular and Cellular Biology/Genetics0 citations
Semantic Scholar
Abstract 2137: A high proportion of protein phosphorylation sites identified in CPTAC breast cancer and lung adenocarcinoma may result from direct phosphorylation by CDK1
Dun-Rui Wang, X. Qian, Sara Eng, L. M. Miller Jenkins +2 more
2020Clinical research0 citations
Semantic Scholar
Abstract 2586: Identification of cancer-associated RhoA mutants and analogous K-Ras mutants that induce gain-of function despite low GTP binding
X. Qian, A. Papageorge, Dun-Rui Wang, B. Tripathi +7 more
2020Immunology0 citations
Semantic Scholar

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